利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

128 条记录 (耗时 0.047 秒)

    ROLLING APPARATUS
    113.
    发明申请
    ROLLING APPARATUS 有权
    滚动装置

    公开(公告)号：US20090038713A1

    公开(公告)日：2009-02-12

    申请号：US12293189

    申请日：2007-05-16

    申请人： Koji Ueda ,  Toru Ueda ,  Naoya Seno ,  Nobuaki Mitamura

    发明人： Koji Ueda ,  Toru Ueda ,  Naoya Seno ,  Nobuaki Mitamura

    IPC分类号： C23C8/26 ,  C23C8/32

    CPC分类号： C22C38/02 ,  C21D1/06 ,  C21D1/10 ,  C21D9/40 ,  C21D2211/001 ,  C21D2211/008 ,  C22C38/04 ,  C22C38/18 ,  C23C8/26 ,  C23C8/32 ,  F16C19/06 ,  F16C19/364 ,  F16C29/0647 ,  F16C33/32 ,  F16C33/34 ,  F16C33/62 ,  F16C33/64 ,  Y02P10/253 ,  Y10S148/906

    摘要： A rolling apparatus including an external member having a raceway surface on an inner peripheral surface thereof, an internal member having a raceway surface on an outer peripheral surface thereof, and a plurality of rolling elements which are rotatably provided between the raceway surface of the external member and the raceway surface of the internal member. A surface of at least one of the internal member, the external member, and the rolling elements is subjected to carbonitriding or nitriding; an area percentage of a nitride containing Si and Mn is 1% or more and 20% or less; surface hardness is HV750 or more. When depth from the raceway surface or depth from a rolling surface of the rolling element is defined as Z and diameter of the rolling element is defined as d, hardness at Z=0.045 d is HV650 to 850, and hardness at Z=0.18 d is HV400 to 800.

    摘要翻译： 一种滚动装置，包括在其内周面上具有滚道面的外部构件，在其外周面上具有滚道面的内部构件，以及多个滚动体，其可旋转地设置在外部构件的滚道面之间 和内部构件的轨道面。 内部构件，外部构件和滚动体中的至少一个的表面经受碳氮共渗或氮化; 含有Si和Mn的氮化物的面积百分比为1％以上20％以下; 表面硬度为HV750以上。 当从滚道表面的深度或滚动体的滚动面的深度定义为Z，滚动体的直径为d时，Z = 0.045d的硬度为HV650〜850，Z = 0.18d的硬度为 HV400至800。

    Optically active 1-(fluoro-, trifluoromethyl-or trifluoromethoxy-substituted phenyl) alkylamine n-monoalkyl derivatives and process for producing same
    116.
    发明授权
    Optically active 1-(fluoro-, trifluoromethyl-or trifluoromethoxy-substituted phenyl) alkylamine n-monoalkyl derivatives and process for producing same 有权
    光学活性1-（氟 - ，三氟甲基 - 或三氟甲氧基取代的苯基）烷基胺n-单烷基衍生物及其制备方法

    公开(公告)号：US07186865B2

    公开(公告)日：2007-03-06

    申请号：US10476650

    申请日：2003-09-05

    申请人： Akihiro Ishii ,  Masatomi Kanai ,  Yokusu Kuriyama ,  Manabu Yasumoto ,  Kenjin Inomiya ,  Takashi Ootsuka ,  Koji Ueda

    发明人： Akihiro Ishii ,  Masatomi Kanai ,  Yokusu Kuriyama ,  Manabu Yasumoto ,  Kenjin Inomiya ,  Takashi Ootsuka ,  Koji Ueda

    IPC分类号： C07C211/00

    CPC分类号： C07C209/62 ,  C07B2200/07 ,  C07C211/29 ,  C07C217/58 ,  C07C249/02 ,  C07C251/24

    摘要： An optically active 1-(fluoro-, trifluoromethyl- or trifluoromethoxy-substituted phenyl)alkylamine N-monoalkyl derivative represented by the formula 4 is produced by a process including (a) reacting an optically active secondary amine, represented by the formula 1, with an alkylation agent R2—X, in the presence of a base, thereby converting the secondary amine into an optically active tertiary amine represented by the formula 3; and (b) subjecting the tertiary amine to a hydrogenolysis, thereby producing the N-monoalkyl derivative, wherein R represents a fluorine atom, trifluoromethyl group or trifluoromethoxy group, n represents an integer of from 1 to 5, each of R1 and R2 independently represents an alkyl group having a carbon atom number of from 1 to 6, Me represents a methyl group, Ar represents a phenyl group or 1- or 2-naphthyl group, * represents a chiral carbon, and X represents a leaving group.

    摘要翻译： 由式4表示的光学活性1-（氟 - ，三氟甲基 - 或三氟甲氧基取代的苯基）烷基胺N-单烷基衍生物通过以下方法制备，该方法包括：（a）使由式1表示的光学活性仲胺与式 烷基化剂R 2 -X在碱的存在下，由此将仲胺转化成由式3表示的光学活性叔胺; 和（b）使叔胺进行氢解，从而制备N-单烷基衍生物，其中R表示氟原子，三氟甲基或三氟甲氧基，n表示1〜5的整数，R 1 独立地表示碳原子数1〜6的烷基，Me表示甲基，Ar表示苯基或1-或2-萘基， *表示手性碳，X表示离去基团。

    Working machine
    117.
    发明申请
    Working machine 审中-公开
    工作机

    公开(公告)号：US20060265915A1

    公开(公告)日：2006-11-30

    申请号：US11414380

    申请日：2006-05-01

    申请人： Yutaka Toji ,  Yoichiro Yamazaki ,  Hidekazu Oka ,  Koji Ueda

    发明人： Yutaka Toji ,  Yoichiro Yamazaki ,  Hidekazu Oka ,  Koji Ueda

    IPC分类号： E02F5/02

    CPC分类号： E02F9/2242 ,  E02F9/2253 ,  E02F9/2292 ,  E02F9/2296

    摘要： A working machine includes a hydraulic control apparatus. In a straight travel valve of the hydraulic control apparatus, a communication path and a control valve that opens and closes the communication path are provided. During a combined operation of traveling operation and working operation, a working pressure and a traveling pressure are taken in as pilot pressures on either side. During a small traveling operation in which the traveling operation amount is small, the communication path is unconditionally closed. During a large traveling operation in which the traveling operation amount is large, if the working pressure is higher than the traveling pressure, the communication path is open, and if the working pressure is lower than the traveling pressure, the communication path is closed.

    摘要翻译： 工作机械包括液压控制装置。 在液压控制装置的直动式阀中，设置有开闭通气路的连通路和控制阀。 在行驶操作和工作操作的组合操作中，工作压力和行驶压力作为任一侧的先导压力。 在行驶操作量小的小行驶操作中，通信路径无条件地关闭。 在行驶操作量大的大型行驶操作中，如果工作压力高于行驶压力，则连通路径打开，并且如果工作压力低于行驶压力，则连通路径关闭。

    Process for producing 2'-deoxy-2'-fluorouridine
    118.
    发明申请
    Process for producing 2'-deoxy-2'-fluorouridine 失效
    制备2'-脱氧-2'-氟尿苷的方法

    公开(公告)号：US20060247433A1

    公开(公告)日：2006-11-02

    申请号：US10552463

    申请日：2004-04-09

    申请人： Akihiro Ishii ,  Takashi Ootsuka ,  Masatomi Kanai ,  Yokusu Kuriyama ,  Manabu Yasumoto ,  Kenjin Inomiya ,  Koji Ueda

    发明人： Akihiro Ishii ,  Takashi Ootsuka ,  Masatomi Kanai ,  Yokusu Kuriyama ,  Manabu Yasumoto ,  Kenjin Inomiya ,  Koji Ueda

    IPC分类号： C07H19/12

    CPC分类号： C07H19/067 ,  Y02P20/55

    摘要： 1-β-D-Arabinofuranosyluracil in 3′,5′-hydroxyl-protected form is reacted with a trifluoromethanesulfonylating agent in the presence of an organic base to convert it into a 2′-triflate form, and then it is reacted with a fluorinating agent containing “a salt or complex formed by an organic base and hydrofluoric acid” to produce 2′-deoxy-2′-fluorouridine in 3′,5′-hydroxyl-protected form. A deprotecting agent is further caused to act thereon to obtain 2′-deoxy-2′-fluorouridine. The 2′-deoxy-2′-fluorouridine obtained can efficiently be purified by temporarily converting it into a 3′,5′-diacetyl form, recrystallizing the 3′,5′-diacetyl form, and then deacetylating it. Thus, high-purity 2′-deoxy-2′-fluorouridine can be produced.

    摘要翻译： 3'，5'-羟基保护形式的1-β-D-阿拉伯呋喃糖尿嘧啶在有机碱的存在下与三氟甲磺酰化剂反应，将其转化为2,3-三氟甲磺酸酯形式，然后与氟化 含有“由有机碱和氢氟酸形成的盐或络合物”的试剂以产生3'，5'-羟基保护形式的2'-脱氧-2'-氟尿苷。 进一步使脱保护剂作用于其上，得到2'-脱氧-2'-氟尿苷。 所得到的2'-脱氧-2'-氟尿苷可以通过暂时转化为3'，5'-二乙酰基形式，重结晶3'，5'-二乙酰基形式，然后脱乙酰化而有效地纯化。 因此，可以制备高纯度2'-脱氧-2'-氟尿苷。

    Process for producing trifluoromethyl-substituted 2-alkoxyacetophenone derivatives
    119.
    发明申请
    Process for producing trifluoromethyl-substituted 2-alkoxyacetophenone derivatives 失效
    制备三氟甲基取代的2-烷氧基苯乙酮衍生物的方法

    公开(公告)号：US20060128976A1

    公开(公告)日：2006-06-15

    申请号：US11347390

    申请日：2006-02-06

    申请人： Akihiro Ishii ,  Masatomi Kanai ,  Yokusu Kuriyama ,  Manabu Yasumoto ,  Kenjin Inomiya ,  Takashi Ootsuka ,  Koji Ueda

    发明人： Akihiro Ishii ,  Masatomi Kanai ,  Yokusu Kuriyama ,  Manabu Yasumoto ,  Kenjin Inomiya ,  Takashi Ootsuka ,  Koji Ueda

    IPC分类号： C07D317/00 ,  C07D309/00

    CPC分类号： C07D317/22 ,  C07C43/315 ,  C07C45/57 ,  C07C45/59 ,  C07C45/60 ,  C07C49/84 ,  C07D317/16 ,  C07C49/80

    摘要： A process for producing a brominated acetal (represented by the formula 3) includes (a) brominating a trifluoromethyl-substituted acetophenone by Br2 in the presence of an alkylene diol. It is optional to produce a trifluoromethyl-substituted 2-alkoxyacetophenone derivative (represented by the formula 9) by (b) reacting the brominated acetal with a metal alkoxide, thereby converting the brominated acetal into an ether; and (c) hydrolyzing the ether in the presence of an acid catalyst to remove an acetal group from the ether, thereby producing the 2-alkoxyacetophenone derivative. Alternatively, the 2-alkoxyacetophenone can be produced by (a) reacting a trifluoromethyl-substituted phenacyl halide with an acetalization agent, thereby converting the phenacyl halide into an acetal; (b) reacting the acetal with a metal alkoxide, thereby converting the acetal into an ether; and (c) hydrolyzing the ether in the presence of an acid catalyst to remove the acetal group from the ether.

    摘要翻译： 制备溴化缩醛的方法（由式3表示）包括（a）在亚烷基二醇的存在下用Br 2 H 3溴化三氟甲基取代的苯乙酮。 （b）使溴化缩醛与金属醇盐反应，从而将溴化缩醛转化成醚，任选地制备三氟甲基取代的2-烷氧基苯乙酮衍生物（由式9表示） 和（c）在酸催化剂的存在下水解醚，以从乙醚中除去缩醛基，从而制备2-烷氧基苯乙酮衍生物。 或者，2-烷氧基苯乙酮可以通过以下方法制备：（a）使三氟甲基取代的苯甲酰甲基卤化物与缩醛化剂反应，从而将苯甲酰甲酰卤转化成缩醛; （b）使缩醛与金属醇盐反应，从而将缩醛转化成醚; 和（c）在酸催化剂存在下水解该醚，以从乙醚中除去缩醛基。

    Process for producing trifluoromethyl- substituted 2- alkoxyacetophenone derivatives
    120.
    发明授权
    Process for producing trifluoromethyl- substituted 2- alkoxyacetophenone derivatives 有权
    制备三氟甲基取代的2-烷氧基苯乙酮衍生物的方法

    公开(公告)号：US07053248B2

    公开(公告)日：2006-05-30

    申请号：US10473399

    申请日：2003-08-08

    申请人： Akihiro Ishii ,  Masatomi Kanai ,  Yokusu Kuriyama ,  Manabu Yasumoto ,  Kenjin Inomiya ,  Takashi Ootsuka ,  Koji Ueda

    发明人： Akihiro Ishii ,  Masatomi Kanai ,  Yokusu Kuriyama ,  Manabu Yasumoto ,  Kenjin Inomiya ,  Takashi Ootsuka ,  Koji Ueda

    IPC分类号： C07C45/61

    CPC分类号： C07D317/22 ,  C07C43/315 ,  C07C45/57 ,  C07C45/59 ,  C07C45/60 ,  C07C49/84 ,  C07D317/16 ,  C07C49/80

    摘要： A process for producing a brominated acetal (represented by the formula 3) includes (a) brominating a trifluoromethyl-substituted acetophenone by Br2 in the presence of an alkylene diol. It is optional to produce a trifluoromethyl-substituted 2-alkoxyacetophenone derivative (represented by the formula 9) by (b) reacting the brominated acetal with a metal alkoxide, thereby converting the brominated acetal into an ether; and (c) hydrolyzing the ether in the presence of an acid catalyst to remove an acetal group from the ether, thereby producing the 2-alkoxyacetophenone derivative. Alternatively, the 2-alkoxyacetophenone can be produced by (a) reacting a trifluoromethyl-substituted phenacyl halide with an acetalization agent, thereby converting the phenacyl halide into an acetal; (b) reacting the acetal with a metal alkoxide, thereby converting the acetal into an ether; and (c) hydrolyzing the ether in the presence of an acid catalyst to remove the acetal group from the ether.

    摘要翻译： 制备溴化缩醛的方法（由式3表示）包括（a）在亚烷基二醇的存在下用Br 2 H 3溴化三氟甲基取代的苯乙酮。 （b）使溴化缩醛与金属醇盐反应，从而将溴化缩醛转化成醚，任选地制备三氟甲基取代的2-烷氧基苯乙酮衍生物（由式9表示） 和（c）在酸催化剂的存在下水解醚，以从乙醚中除去缩醛基，从而制备2-烷氧基苯乙酮衍生物。 或者，2-烷氧基苯乙酮可以通过以下方法制备：（a）使三氟甲基取代的苯甲酰甲基卤化物与缩醛化剂反应，从而将苯甲酰甲酰卤转化成缩醛; （b）使缩醛与金属醇盐反应，从而将缩醛转化成醚; 和（c）在酸催化剂存在下水解该醚，以从乙醚中除去缩醛基。