公开(公告)号：US10881777B2

公开(公告)日：2021-01-05

申请号：US16154755

申请日：2018-10-09

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Thomas E. Meyer ,  David B. Lura ,  Martin T. Gerber

IPC: A61M1/16 ,  A61M1/14 ,  A61M1/28 ,  A61M1/34 ,  B01D15/08 ,  B01D15/36

Abstract: A blood based solute monitoring system for measuring at least one blood solute species that has a first recirculation flow path in fluid communication with a dialyzer. The first recirculation flow path is configured to allow a fluid to recirculate through a dialyzer such that the concentration of at least one solute species in the fluid becomes equilibrated to the solute species concentration of the blood in a blood compartment of the dialyzer. The blood solute monitoring system has at least one sensor to measure a fluid characteristic.

公开(公告)号：US10850016B2

公开(公告)日：2020-12-01

申请号：US13757728

申请日：2013-02-01

Applicant: Medtronic, Inc.

Inventor： Thomas E. Meyer ,  David B. Lura ,  Bryant J. Pudil ,  Martin T. Gerber ,  Mark F. Daniels

IPC: A61M1/16 ,  A61M1/34 ,  A61M1/36

Abstract: Systems and methods for cleaning and disinfecting a medical therapy device that delivers any one of hemodialysis, hemodiafiltration and hemofiltration. The system has a base module that has at least one segment of a controlled compliant flow path and at least one pair of jumpered ports configured on the base module. One or more components have connections connectable to the jumpered ports of the base module to provide for fluid communication between the segment of the controlled compliant flow path in the base module and a flow path defined by the one or more components. The base module is connected to the one or more components that define a flow path configurable for carrying out in part at least one function performed during any one of hemodialysis, hemodiafiltration or hemofiltration.

公开(公告)号：US10758659B2

公开(公告)日：2020-09-01

申请号：US15666609

申请日：2017-08-02

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber ,  Christopher M. Hobot

IPC: A61M1/28 ,  A61M1/16 ,  A61M1/34 ,  G16H20/17

Abstract: The invention relates to systems and methods for optimizing a peritoneal dialysate prescription based on one or more fluid characteristics sensed from a filtrate removed from a patient. The systems and methods include sensors, flow paths, and processors to adjust a peritoneal dialysate prescription and deliver peritoneal dialysis therapy to a patient based on the adjusted prescription. The method can include the steps of removing fluid from a peritoneal cavity of a patient; sampling one or more characteristics of the removed fluid; and adjusting a peritoneal dialysate prescription based on the one or more characteristics of the removed fluid. The system can include a peritoneal dialysate effluent line; at least one concentrate source fluidly connectable to the peritoneal dialysate flow path; and at least one sensor positioned in the peritoneal dialysate effluent line.

公开(公告)号：US20200261888A1

公开(公告)日：2020-08-20

申请号：US16691924

申请日：2019-11-22

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Martin T. Gerber ,  Christopher M. Hobot

IPC: B01J20/34 ,  A61M1/16 ,  B01J20/02

Abstract: The invention relates to devices, systems, and methods for precision recharging of sorbent materials in a sorbent module. The devices, systems, and methods use manufacturing characteristics of the sorbent module to set recharge parameters used in recharging the sorbent material.

公开(公告)号：US20200179677A1

公开(公告)日：2020-06-11

申请号：US16790414

申请日：2020-02-13

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber

IPC: A61N1/05

Abstract: The disclosure is directed to securing electrodes of a medical lead adjacent to a target tissue site. The medical lead may include one or more threaded fixation structures disposed circumferentially about the outer surface of the lead body, or elongated member, that resembles a “screw” or “auger.” During implantation, a clinician may rotate the entire lead to “screw” the lead into the tissue of the patient until electrodes of the lead reside adjacent to a target tissue. In this manner, the threaded fixation structure secures the lead within the patient to resist lead migration and improper therapy and provide a fine adjustment for depth of placement. The threaded fixation structure may be disposed on a portion of the lead proximal to or distal to the electrodes of the lead or over the portion of the lead that includes the electrodes.

公开(公告)号：US10668202B2

公开(公告)日：2020-06-02

申请号：US16597086

申请日：2019-10-09

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Martin T. Gerber ,  David B. Lura ,  Thomas E. Meyer

IPC: A61M1/16 ,  B01D15/18 ,  B01D15/22 ,  B01J39/12 ,  B01J20/06 ,  B01J20/08 ,  B01J20/20 ,  B01J20/02 ,  B01J20/28 ,  G01N30/60

Abstract: Parallel modules for in-line recharging of sorbent materials using alternate duty cycles for a sorbent cartridge. The sorbent cartridge can have two or more modules contained therein having connectors connecting each of the modules. One or more of the modules can be reusable and the sorbent materials therein can be recharged.

公开(公告)号：US20200155748A1

公开(公告)日：2020-05-21

申请号：US16674532

申请日：2019-11-05

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber ,  Christopher M. Hobot

IPC: A61M1/28 ,  G16H20/40

Abstract: The invention relates to devices, systems, and methods for measuring dialysis adequacy in patients undergoing peritoneal dialysis treatment. The devices, systems, and methods use one or more flow sensors and one or more solute sensors to measure the concentration of a uremic solute and volume of the peritoneal dialysate removed from the patient, and to calculate the dialysis adequacy based on the measured peritoneal dialysate concentration and volume.

公开(公告)号：US10583235B2

公开(公告)日：2020-03-10

申请号：US15582830

申请日：2017-05-01

Applicant: Medtronic, Inc.

Inventor： Christopher M. Hobot ,  Martin T. Gerber

IPC: A61M1/16 ,  A61K33/00 ,  A61K33/06 ,  A61K31/7004

Abstract: Systems and methods of generating a customized dialysate solution are provided. The system and methods use stock concentrates, with the addition of spikes to generate a customized dialysate solution based on the needs of the patient.

公开(公告)号：US10532141B2

公开(公告)日：2020-01-14

申请号：US15840102

申请日：2017-12-13

Applicant: Medtronic, Inc.

Inventor： Thomas E. Meyer ,  David B. Lura ,  Bryant J. Pudil ,  Martin T. Gerber

IPC: A61M1/16 ,  A61M1/34 ,  A61M1/36

Abstract: Systems and methods for controlling fluid movement and volumes of fluid between a subject and a controlled compliant flow path. The controlled compliant flow path has a means for selectively metering in and metering out fluid from the controlled compliant flow path. An extracorporeal flow path is in fluid communication with the controlled compliant flow path across a semi-permeable membrane where the extracorporeal flow path has a first terminal end and a second terminal end.

公开(公告)号：US20190321536A1

公开(公告)日：2019-10-24

申请号：US16455822

申请日：2019-06-28

Applicant: Medtronic, Inc.

Inventor： VenKatesh R. Manda ,  Martin T. Gerber ,  Christopher M. Hobot

IPC: A61M1/28 ,  A61M1/16 ,  C02F1/00 ,  C02F1/02 ,  C02F1/28 ,  C02F1/32 ,  A61K31/716 ,  A61K33/00 ,  A61K33/06 ,  A61K31/19 ,  A61K33/14 ,  A61K31/7004 ,  A61L2/00 ,  C02F1/44 ,  C02F1/42

Abstract: Systems and methods of generating peritoneal dialysate are provided. The systems and methods use a water purification module, a sterilization module and concentrates to prepare a bolus of peritoneal dialysate from source water for use with an non-integrated cycler.