公开(公告)号：USRE39420E1

公开(公告)日：2006-12-05

申请号：US09678218

申请日：2000-09-29

申请人： Tomio Kimura ,  Yasuo Noguchi ,  Akira Nakao ,  Keisuke Suzuki ,  Shigeru Ushiyama ,  Akihiro Kawara ,  Masaaki Miyamoto

发明人： Tomio Kimura ,  Yasuo Noguchi ,  Akira Nakao ,  Keisuke Suzuki ,  Shigeru Ushiyama ,  Akihiro Kawara ,  Masaaki Miyamoto

IPC分类号： A61K31/40 ,  C07D207/333 ,  C07D207/335 ,  C07D207/337

CPC分类号： C07D207/333 ,  C07D207/335 ,  C07D207/337

摘要： Compounds of formula (I) and (II): [wherein R is hydrogen, halogen or alkyl; R1 is alkyl, amino or substituted amino; R2 is optionally substituted phenyl; R3 is hydrogen, halogen or optionally substituted alkyl; R4 is hydrogen, optionally substituted alkyl, cycloalkyl, aryl, or aralkyl] have valuable analgesic, anti-inflammatory, anti-pyretic and anti-allergic activities and have the ability to inhibit the production of leukotrienes and to inhibit bone resorption. They are relatively free from the side effects which generally result from the administration of compounds having these kinds of activities.

摘要翻译： 式（I）和（II）的化合物：[其中R是氢，卤素或烷基; R 1是烷基，氨基或取代的氨基; R 2是任选取代的苯基; R 3是氢，卤素或任选取代的烷基; R 4是氢，任选取代的烷基，环烷基，芳基或芳烷基]具有有价值的镇痛，抗炎，抗裂解和抗过敏活性，并且具有抑制白三烯生产的能力和 以抑制骨吸收。 它们相对没有通常由施用具有这些活性的化合物引起的副作用。

公开(公告)号：US5205817A

公开(公告)日：1993-04-27

申请号：US820859

申请日：1992-01-17

申请人： Morito Idemoto ,  Naohiko Inoue ,  Yasuo Noguchi

发明人： Morito Idemoto ,  Naohiko Inoue ,  Yasuo Noguchi

IPC分类号： A61B17/22 ,  A61B17/32 ,  A61B18/00 ,  A61M1/00

CPC分类号： A61C8/0089 ,  A61B17/320068 ,  A61B2017/22018 ,  A61B2017/320072 ,  A61B2018/00011 ,  A61B2217/005 ,  A61C3/03

摘要： A surgical instrument comprises an ultrasonic source (7) and an ultrasonic vibration transmitter (8) connected to the source (7), which generates ultrasonic mechanical vibration. The ultrasonic vibration transducer includes a plurality of ring-shaped cutting blade portions (14) provided on an outer periphery of an operational part (9) which contacts organic tissue, and a liquid passage (11) through the transducer. The liquid passage opens at a front end (12) of the operational part and at recesses (13) between the blade portions. The surgical instrument cuts or incises organic tissue by ultrasonic vibration.

摘要翻译： PCT No.PCT / JP90 / 00627 Sec。 371日期：1992年1月17日 102（e）日期1992年1月17日PCT提交1990年5月17日PCT公布。 公开号WO91 / 17716 PCT 日期：1991年11月28日。手术器械包括超声波源（7）和连接到源（7）的超声波振动发射器（8），其产生超声机械振动。 超声波振动换能器包括设置在与有机组织接触的操作部分（9）的外周上的多个环形切割刀片部分（14）和通过换能器的液体通道（11）。 液体通道在操作部分的前端（12）处和叶片部分之间的凹部（13）处打开。 手术器械通过超声波振动切割或切开有机组织。

公开(公告)号：US4982735A

公开(公告)日：1991-01-08

申请号：US274122

申请日：1988-11-18

申请人： Kazuhiko Yagata ,  Yasuo Noguchi

发明人： Kazuhiko Yagata ,  Yasuo Noguchi

IPC分类号： A61H31/00 ,  A61H31/02 ,  A61M16/00 ,  A61M16/06

CPC分类号： A61M16/00 ,  A61M16/0677 ,  A61H2031/025 ,  A61M2016/0021

摘要： An artificial ventilator includes a dome for covering the precordial and the sides of the thoracoabdominal of a patient, a blower to be used for applying negative and positive pressures within the dome, a regulator for adjusting a pressure, and the like. The valve switching device is controlled by a respiration detection system. In the respiration detection system, a pyrolelectric element is used as a respiratory sensor for detecting a temperature change rate caused by an inspired and expired air flow. The temperature change rate signal obtained by the sensor is compared with a threshold value set by a variable resistor, the start timings of expired air and inspired air are detected in accordance with the comparison result, and air inspiration and expiration start timing signals are outputted. Further, the artificial ventilator can be provided with various functions of forced respiration and intermittent deep breathing by means of a timer, synchronization only with air inspiration timings, reduction of frequency of respiration assistance for the intention not to use the ventilator in the near future, backup during apnea, and the like. The artificial ventilator allows a physilogical respiration assistance matching the patient's physiological intention by synchronizing with the patient' s respiration. Thus, an effort and pain in breathing with a conventional mechanical ventilation can be avoided so that the artificial ventilator is suitable for a long term use and useful for a quick recovery of respiration function of an acute respiratory failure patient.

公开(公告)号：US4832683A

公开(公告)日：1989-05-23

申请号：US60394

申请日：1987-05-15

申请人： Morito Idemoto ,  Yasuo Noguchi

发明人： Morito Idemoto ,  Yasuo Noguchi

IPC分类号： A61B17/32 ,  A61B17/56 ,  A61B18/00 ,  A61M1/00

CPC分类号： A61B17/320068 ,  A61B2017/320072 ,  A61B2017/320076 ,  A61B2018/00011 ,  A61B2217/005 ,  A61B2217/007 ,  A61M1/0062

摘要： A surgical instrument for cutting and separating biological tissue by employing ultrasonic vibration, particularly for cutting bones, separating the periosteum, and cutting and separating a coherent mass such as a calcium mass. An ultrasonic vibration-transmitting tool (5) which is connected to an ultrasonic vibration source (4) and performs mechanical vibration at the frequency of the ultrasonic waves has a spoon-shaped working portion (7) which is provided with at least one of a blade-shaped portion (25) forming a predetermined angle with respect to the direction of the mechanical vibration at the frequency of the ultrasonic waves and a blade-shaped portion (23, 24) substantially parallel with the direction of the vibration, the spoon-shaped working portion being adapted to be brought into contact with the biological tissue, and a liquid passage (21) passing through the interior of the ultrasonic vibration-transmitting tool, the liquid passage having an opening (22) which opens into the working portion. Further, by making of ceramic the whole part or the surface portion of the working portion (7) which is provided with the blade-shaped portion to be brought into contact with the biological tissue, it is possible to prevent wear deformation of the blade-shaped portion, and also to prevent transmission of electrical shocks to the nervous tissue in the event of a simple electrical fault state.

摘要翻译： PCT No.PCT / JP86 / 00361 Sec。 371日期1987年5月15日 102（e）日期1987年5月15日PCT提交1986年7月15日PCT公布。 第WO87 / 01575号公报 日期：1987年3月26日。一种手术器械，其通过采用超声振动，特别是用于切割骨骼，分离骨膜以及切割和分离诸如钙质量的相干团块来切割和分离生物组织。 与超声波振动源（4）连接并以超声波的频率进行机械振动的超声波振动传递工具（5）具有勺状加工部（7），该勺形加工部（7）具有： 相对于超声波的频率处的机械振动的方向形成预定角度的叶片形部分（25）和基本上与振动方向平行的叶片形部分（23,24） 所述液体通道具有通向所述工作部的开口部（22），所述液体通路具有与所述生物体组织接触的液体通路（21），所述液体通路（21）穿过所述超声波振动传递工具的内部。 此外，通过使设置有与生物体组织接触的刀片状部分的工作部分（7）的整个部分或表面部分制成陶瓷，可以防止刀片状部分的磨损变形， 并且还能够在简单的电气故障状态的情况下防止对神经组织的电击传播。

公开(公告)号：US20090240791A1

公开(公告)日：2009-09-24

申请号：US12395147

申请日：2009-02-27

申请人： Hideki Sakurai ,  Yasuo Noguchi

发明人： Hideki Sakurai ,  Yasuo Noguchi

IPC分类号： G06F15/173

CPC分类号： G06F8/65

摘要： A management node for managing a program update time refers to an update management table in which a plurality of managed nodes are classified into a plurality of groups and the sequence of program updating of the groups is defined. The management node sequentially selects the groups in accordance with the sequence of program updating in such a manner that after program updating processing has been completed in all managed nodes included in the selected group, the next group is selected. The management node refers to the update management table, transmits a program update request to each of the managed nodes included in the selected group, receives an update completion notification from the managed node, and notifies update management information storing means that the update processing has been completed in the managed node.

摘要翻译： 用于管理节目更新时间的管理节点是指将多个受管节点分类为多个组的更新管理表，并且定义组的节目更新的顺序。 管理节点按照程序更新顺序顺序地选择组，使得在包括在所选择的组中的所有被管理节点中完成节目更新处理之后，选择下一组。 管理节点参照更新管理表，向所选择的组中包含的各被管理节点发送节目更新请求，从被管理节点接收到更新完成通知，并且向更新管理信息存储单元通知更新处理已被 在受管节点中完成。

公开(公告)号：US5592660A

公开(公告)日：1997-01-07

申请号：US912525

申请日：1992-07-13

申请人： Haruo Yokota ,  Yasuo Noguchi ,  Naoki Akaboshi ,  Katsumi Hayashi ,  Seigo Hirosue

发明人： Haruo Yokota ,  Yasuo Noguchi ,  Naoki Akaboshi ,  Katsumi Hayashi ,  Seigo Hirosue

IPC分类号： G06F12/00 ,  G06F13/00 ,  G06F17/30

CPC分类号： G06Q20/108 ,  G06F17/30368 ,  Y10S707/99938

摘要： A database system including a transaction database system processing device for executing a transaction database process and a decision support database system processing device for executing a decision support process. The database system further includes a transaction database storage device, provided with the transaction database device, for retaining a transaction database created and updated by the transaction database process, a first and second database storage device, each provided with the decision support database device, and each for retaining a first and a second decision database, respectively, for use in a decision support process, a delayed updating device, provided with the decision support database device, for receiving a log created based on the transaction database at each of a predetermined time interval, and for alternatively supplying both the log received at a current predetermined time interval and the log received immediately preceding the current predetermined time interval to the first database storage device and to the second database storage device at each predetermined time interval, and a retrieving device, provided with decision support database device, for executing a retrieving process for the second decision database stored in the second database storage device when the delayed updating device supplies both logs to the first database storage device and for executing a retrieving process for the first decision database stored in the first database storage device when the delayed updating device supplies both logs to the second database storage device.

摘要翻译： 一种数据库系统，包括用于执行交易数据库处理的交易数据库系统处理装置和用于执行决策支持处理的决策支持数据库系统处理装置。 所述数据库系统还包括具有交易数据库装置的交易数据库存储装置，用于保留由交易数据库处理程序创建和更新的交易数据库;第一和第二数据库存储装置，每个提供有决策支持数据库装置;以及 每个用于分别保留用于决策支持过程的第一和第二决策数据库，具有决策支持数据库设备的延迟更新设备，用于在每个预定时间接收基于交易数据库创建的日志 并且用于将以当前预定时间间隔接收的日志和在当前预定时间间隔之前接收的日志两者提供给第一数据库存储设备，并将每个预定时间间隔提供给第二数据库存储设备;以及检索设备 提供决策支持数据库设备，用于执行 当所述延迟更新装置将所述两个日志提供给所述第一数据库存储装置时，以及为所述第一数据库存储装置中存储的所述第一判定数据库执行检索处理时，所述第二数据库存储装置中存储的所述第二判定数据库的检索处理， 设备将两个日志提供给第二个数据库存储设备。

公开(公告)号：US5180363A

公开(公告)日：1993-01-19

申请号：US813053

申请日：1991-12-23

申请人： Morito Idemoto ,  Naohiko Inoue ,  Yasuo Noguchi

发明人： Morito Idemoto ,  Naohiko Inoue ,  Yasuo Noguchi

IPC分类号： A61B17/32 ,  A61B18/00 ,  A61B18/12 ,  A61F9/007 ,  A61M3/02 ,  B06B1/02 ,  B06B3/00

CPC分类号： B06B3/00 ,  A61B17/320068 ,  B06B1/0253 ,  A61B18/1206 ,  A61B2017/320072 ,  A61B2017/320076 ,  A61B2017/32008 ,  A61B2018/00011 ,  A61B2217/007 ,  A61F9/00745 ,  A61M3/0279 ,  B06B2201/76

摘要： A surgical operation device comprising an ultrasonic piezoelectric transducer for generating ultrasonic vibrations, an oscillation feedback type oscillator for supplying high-frequency power to the ultrasonic transducer, a vibration transmitter connected to the ultrasonic transducer for transmitting and amplifying mechanical vibrations at an ultrasonic frequency, a suction unit and an irrigator. The ultrasonic transducer includes a bolted Langevin type transducer. The feedback circuit of the oscillation feedback type oscillator includes an oscillation voltage detector, a phase comparator, a low pass filter, a differential amplifier, and a voltage controlled oscillator. Thus, the mechanical resonant frequency can be traced in a wide range of fluctuations of a load on the vibration transmitter during vibration and vibrations can start an appropriate mechanical resonate frequency irrespective of the load status of the vibration transmitter at the start-up.

摘要翻译： 一种外科手术装置，包括用于产生超声波振动的超声波压电换能器，用于向所述超声波换能器供给高频电力的振荡反馈型振荡器，连接到所述超声波换能器的振动发生器，用于以超声波频率发射和放大机械振动， 抽吸单元和冲洗器。 超声波换能器包括一个螺栓连接的朗格温型换能器。 振荡反馈型振荡器的反馈电路包括振荡电压检测器，相位比较器，低通滤波器，差分放大器和压控振荡器。 因此，机械谐振频率可以在振动发生器的负载波动的宽范围内进行跟踪，振动可以在启动时与振动发送器的负载状态无关地启动适当的机械谐振频率。

公开(公告)号：US5042461A

公开(公告)日：1991-08-27

申请号：US350352

申请日：1989-05-11

申请人： Naohiko Inoue ,  Yasuo Noguchi

发明人： Naohiko Inoue ,  Yasuo Noguchi

IPC分类号： A61B17/22 ,  A61B17/32 ,  A61B18/00 ,  A61B19/08 ,  A61M1/00

CPC分类号： A61B17/22012 ,  A61B46/13 ,  A61M1/0084 ,  A61B2017/22008 ,  A61B2017/22037 ,  A61B2017/32008 ,  A61B2017/320084 ,  A61M2202/068 ,  A61M2210/1067

摘要： A horn used in an ultrasonic surgical operating instrument for crushing and removing organic tissue comprises a horn body vibrated by and ultrasonic vibration source for crushing the organic tissue, a removing passage extending through the horn body, through which the crushed tissue is removed outside, a bulkhead disposed in the removing passage, and at least one through hole formed in the bulkhead. The bulkhead and the hole cooperate with each other to reduce a cross-sectional area of the removing passage.

公开(公告)号：US5011471A

公开(公告)日：1991-04-30

申请号：US399549

申请日：1989-08-16

申请人： Kazuoki Miyazaki ,  Yasuo Noguchi ,  Naohiko Inoue ,  Morito Idemoto

发明人： Kazuoki Miyazaki ,  Yasuo Noguchi ,  Naohiko Inoue ,  Morito Idemoto

IPC分类号： A61M3/00 ,  A61B17/22 ,  A61B17/32 ,  A61B19/08 ,  A61M1/00

CPC分类号： A61B17/22012 ,  A61B46/13 ,  A61M1/0084 ,  A61B2017/22008 ,  A61B2017/22037 ,  A61B2017/32008 ,  A61B2017/320084 ,  A61M2202/068 ,  A61M2210/1067

摘要： An excretions treating apparatus comprises a horn (54) which is vibrated by ultrasonics, a pump (6) for pumping cleaning liquid into a passage defined between the horn (54) and a protection cover (13) covering the horn (54), and a suction passage (25) formed in the horn (54). The excrements in a rectum crushed and emulsified by the ultrasonic vibration of the horn (54) and the cleaning liquid is evacuated by a suction pump (12) through the suction passage.

摘要翻译： PCT No.PCT / JP88 / 01319 Sec。 371日期1989年8月16日 102（e）日期1989年8月16日PCT提交1988年12月23日PCT公布。 出版物WO89 / 0561200 日本1996年6月29日。排泄物处理装置包括通过超声波振动的喇叭（54），用于将清洁液体泵送到限定在喇叭（54）和保护盖（13）之间的通道中的泵（6） 喇叭（54）和形成在喇叭（54）中的吸入通道（25）。 通过喇叭（54）的超声波振动粉碎和乳化的直肠中的排泄物和清洁液体通过抽吸通道由抽吸泵（12）抽真空。

公开(公告)号：US4843432A

公开(公告)日：1989-06-27

申请号：US1220

申请日：1987-01-07

申请人： Toshiaki Mizushima ,  Shigeo Ozaki ,  Yukimasa Shinohara ,  Tomoo Tsunenari ,  Yasufumi Takada ,  Yasuo Noguchi

发明人： Toshiaki Mizushima ,  Shigeo Ozaki ,  Yukimasa Shinohara ,  Tomoo Tsunenari ,  Yasufumi Takada ,  Yasuo Noguchi

IPC分类号： G03B21/11 ,  G03G15/00 ,  G03G15/22

CPC分类号： G03G15/6538 ,  G03B21/118 ,  G03G15/223

摘要： An image recording apparatus of this invention includes a microfilm feeder for moving images on a microfilm to a read position; a printer section for forming an image on the microfilm located at the read position on a sheet; a plurality of bin trays for stacking the sheets delivered from the printer section; a sorter for distributing the sheets delivered from the printer section to the bin trays; a case mark detector for detecting a case mark formed in correspondence with a specific one of images of each case on the microfilm; and a CPU for controlling the sorter in accordance with an output from the case mark detector so that different bin trays hold the sheets, on which images of each objective case are formed, in units of cases; and an input unit for inputting a copy set number. The CPU also controls the printer section so as to repeat an operation for sequentially recording the images of each objective case in a predetermined order in units of sets.

摘要翻译： 本发明的图像记录装置包括用于将微缩胶片上的图像移动到读取位置的微缩胶片进给器; 打印机部分，用于在位于纸张上的读取位置的微缩胶卷上形成图像; 用于堆叠从打印机部分传送的纸张的多个纸盘托盘; 分配器，用于将从打印机部分传送的纸张分配到纸盘托盘; 用于检测与微缩胶卷上的每种情况的特定图像相对应地形成的案例标记的案例标记检测器; 以及CPU，用于根据来自盒子标记检测器的输出来控制分类器，使得不同的纸盘托盘以壳体为单位保持形成有每个物镜的图像的纸张; 以及用于输入复印件编号的输入单元。 CPU还控制打印机部分，以重复以套为单位的预定顺序顺序地记录每个目标盒的图像的操作。