公开(公告)号：US5263940A

公开(公告)日：1993-11-23

申请号：US870521

申请日：1992-04-17

申请人： Marshall S. Kriesel

发明人： Marshall S. Kriesel

IPC分类号： A61M37/00 ,  A61M5/14 ,  A61M5/152

CPC分类号： A61M5/152 ,  A61M5/1409

摘要： An elastomeric bladder type infusion device for delivering a beneficial agent, such as a drug to a patient at substantially a constant rate. The device uniquely includes an internally disposed functional substrate which carries the beneficial agent so that it can be mixed with the fluid as the fluid is being introduced into the device to distend the bladder to make it an energy source for controllably dispensing the solution mixture to a patient.

摘要翻译： 一种用于以基本恒定的速率将有益剂例如药物递送到患者的弹性体膀胱型输注装置。 该装置独特地包括内部设置的功能性基底，其携带有益剂，使得当流体被引入装置中时，其可以与流体混合以使囊膨胀以使其成为可控地将溶液混合物分配到 患者。

公开(公告)号：US08231575B2

公开(公告)日：2012-07-31

申请号：US12456153

申请日：2009-06-12

申请人： Marshall S. Kriesel

发明人： Marshall S. Kriesel

IPC分类号： A61M37/00

CPC分类号： A61M5/148 ,  A61M5/141 ,  A61M5/14244 ,  A61M5/16877 ,  A61M5/2448 ,  A61M2005/14506 ,  A61M2205/7545 ,  A61M2209/045

摘要： A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as antibiotics, oncolytics, hormones, steroids, blood clotting agents, analgesics, and like medicinal agents from prefilled containers at a uniform rate. The dispenser uniquely includes a stored energy source that is provided in the form of a compressible-expandable elastomeric member of novel construction that provides the force necessary to continuously and uniformly expel fluid from the device reservoir. The device further includes a fluid flow control assembly that precisely controls the flow of the medicament solution to the patient.

摘要翻译： 一种紧凑的流体分配器，用于以均匀的速率从预装容器中可控地分配流体药物，例如抗生素，溶瘤剂，激素，类固醇，凝血剂，止痛剂等药物。 分配器独特地包括存储的能源，其以新颖结构的可压缩可膨胀弹性体构件的形式提供，其提供连续且均匀地排出来自装置储存器的流体所需的力。 该装置还包括流体流动控制组件，其精确地控制药物溶液向患者的流动。

公开(公告)号：US20100056995A1

公开(公告)日：2010-03-04

申请号：US12455645

申请日：2009-06-03

申请人： Marshall S. Kriesel

发明人： Marshall S. Kriesel

IPC分类号： A61M5/168 ,  A61M5/14

CPC分类号： A61M5/1407 ,  A61M5/1413 ,  A61M5/1454 ,  A61M5/16804 ,  A61M5/16881 ,  A61M39/18 ,  A61M2205/197 ,  A61M2205/583

摘要： A dispensing device for dispensing first and second medicaments to a patient that is made up of first and second stand-alone, interconnectable assemblies. The first of these assemblies comprises a fluid reservoir assembly that houses a fluid reservoir defining component while the second assembly comprises a fluid delivery and control assembly that includes an adding assembly for controllably dispensing the second medicament to the patient, a novel flow control means that functions to control the flow of medicinal fluid from the fluid reservoir of the first assembly toward the patient via a plurality of fluid flow control passageways. Because the stand-alone fluid delivery and control assembly is initially totally separate from the fluid reservoir assembly of the apparatus, the fluid flow passageways of the fluid delivery and control assembly can be effectively sterilized using conventional gamma ray sterilization techniques without adversely affecting the medicament contained within the fluid reservoir of the apparatus.

摘要翻译： 一种用于将第一和第二药物分配给由第一和第二独立的可互连组件构成的患者的分配装置。 这些组件中的第一个包括容纳流体储存器限定部件的流体储存器组件，而第二组件包括流体递送和控制组件，流体输送和控制组件包括用于将第二药剂可控地分配给患者的添加组件， 以经由多个流体流动控制通道来控制药液从第一组件的流体储存器朝向患者的流动。 由于独立的流体输送和控制组件最初与设备的流体储存器组件完全分离，流体输送和控制组件的流体流动通道可以使用常规的γ射线消毒技术被有效地消毒，而不会对包含的药物产生不利影响 在设备的流体储存器内。

公开(公告)号：US07214128B2

公开(公告)日：2007-05-08

申请号：US11045898

申请日：2005-01-27

申请人： Marshall S. Kriesel

发明人： Marshall S. Kriesel

IPC分类号： A22C17/00

CPC分类号： A22B5/201 ,  A01K11/008 ,  A01K29/00 ,  A22B5/007

摘要： A method for measuring the physical characteristics of livestock animals such as cattle and hogs. The apparatus of the invention includes a plurality of strategically positioned cameras that are used to obtain data concerning volumetric, curvilinear (surface) and linear measurements of livestock animals such as cattle and hogs and the full carcasses thereof. In accordance with the method of the invention, the data is analyzed to provide information that substantially assists the commercial producer of livestock animals in producing a high-quality end product for the consumer while adding profitability to the enterprise.

摘要翻译： 一种用于测量牲畜和猪等牲畜的物理特性的方法。 本发明的装置包括多个策略性定位的照相机，其被用于获得关于诸如牛和猪以及其全部屠体的牲畜的体积，曲线（表面）和线性测量的数据。 根据本发明的方法，对数据进行分析，提供基本上协助畜牧业的商业生产者为消费者生产高质量终端产品的信息，同时为企业增加利润。

公开(公告)号：US07169128B2

公开(公告)日：2007-01-30

申请号：US10634487

申请日：2003-08-04

申请人： Marshall S. Kriesel ,  Alan Langerud

发明人： Marshall S. Kriesel ,  Alan Langerud

IPC分类号： A61M37/00

CPC分类号： A61M5/1454 ,  A61M5/141 ,  A61M5/14566 ,  A61M5/16804 ,  A61M5/16827

摘要： A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as antibiotics, oncolytics, hormones, steroids, blood clotting agents, analgesics, and like medicinal agents from a plurality of prefilled containers at a uniform rate. The dispenser uniquely includes a plurality of stored energy source that are provided in the form of compressible-expandable members of novel construction that provide the force necessary to continuously and uniformly expel fluid from a plurality of device reservoirs. The apparatus further includes a plurality of fluid flow control assemblies that precisely control the flow of the medicament solutions from the plurality of device reservoirs to the patient.

摘要翻译： 一种紧凑的流体分配器，用于以均匀速率从多个预充填容器中可控地分配流体药物，例如抗生素，溶瘤剂，激素，类固醇，凝血剂，止痛剂等药物。 分配器独特地包括多个存储的能量源，其以新颖结构的可压缩可扩展构件的形式提供，其提供连续且均匀地排出来自多个装置储存器的流体所需的力。 该装置还包括多个流体流量控制组件，其精确地控制药物溶液从多个装置储存器到患者的流动。

公开(公告)号：US06974373B2

公开(公告)日：2005-12-13

申请号：US10211792

申请日：2002-08-02

申请人： Marshall S. Kriesel

发明人： Marshall S. Kriesel

IPC分类号： A01K11/00 ,  A01K29/00 ,  A22B5/00 ,  A22C18/00

CPC分类号： A22B5/201 ,  A01K11/008 ,  A01K29/00 ,  A22B5/007

摘要： A method and apparatus for measuring the physical characteristics of livestock animals such as cattle and hogs. The apparatus of the invention includes a plurality of strategically positioned cameras that are used to obtain data concerning volumetric, curvilinear (surface) and linear measurements of livestock animals such as cattle and hogs and the full carcasses thereof. In accordance with the method of the invention, the data is analyzed to provide information that substantially assists the commercial producer of livestock animals in producing a high-quality end product for the consumer while adding profitability to the enterprise.

摘要翻译： 一种用于测量牲畜和猪等牲畜的物理特性的方法和装置。 本发明的装置包括多个策略性定位的照相机，其被用于获得关于诸如牛和猪以及其全部屠体的牲畜的体积，曲线（表面）和线性测量的数据。 根据本发明的方法，对数据进行分析，提供基本上协助畜牧业的商业生产者为消费者生产高质量终端产品的信息，同时为企业增加利润。

公开(公告)号：US06416495B1

公开(公告)日：2002-07-09

申请号：US09686650

申请日：2000-10-10

申请人： Marshall S. Kriesel ,  Thomas N. Thompson

发明人： Marshall S. Kriesel ,  Thomas N. Thompson

IPC分类号： A61M3700

CPC分类号： A61M5/152 ,  A61M5/14276 ,  A61M5/145 ,  A61M5/1723 ,  A61M2205/3523 ,  A61M2205/36 ,  A61M2209/045 ,  F03G7/005 ,  Y10S977/777 ,  Y10S977/905

摘要： An implantable fluid delivery apparatus for infusing medicinal fluids into a patient that includes a novel basal delivery system that includes a heat responsive polymer gel material which upon being heated by heater foil uniquely functions as an internal energy source for expelling basal doses of medicinal fluids from the device. The apparatus also includes a bolus delivery system that includes a magnetically responsive polymer gel which, upon being stimulated by an electro-magnet will delivery precise bolus doses of medicinal fluids to the patient.

摘要翻译： 一种用于将药液注入患者体内的可植入液体递送装置，其包括新的基础递送系统，其包括热响应性聚合物凝胶材料，所述热响应性聚合物凝胶材料在被加热器箔加热时独特地用作内部能量源，用于将基础剂量的药液从 设备。 该装置还包括推注递送系统，其包括磁响应聚合物凝胶，其在被电磁体刺激时将向患者递送精确的推注剂量的药液。

公开(公告)号：US06126637A

公开(公告)日：2000-10-03

申请号：US61087

申请日：1998-04-15

申请人： Marshall S. Kriesel ,  Thomas N. Thompson

发明人： Marshall S. Kriesel ,  Thomas N. Thompson

IPC分类号： A61M5/152 ,  A61M5/158 ,  A61M37/00

CPC分类号： A61M5/152 ,  A61M2005/1581 ,  A61M2209/045

摘要： A fluid delivery device having a self-contained stored energy membrane for defining in conjunction with a base a fluid reservoir and for expelling fluids from the reservoir. The device includes novel reservoir filling syringe and filling adapter for conveniently filling the fluid reservoir of the device. Additionally, the device includes a unique crushable or collapsible needle cover which surrounds and protects the infusion cannula until time of use and then readily deforms as the device is connected to the patient so as to permit the needle to cleanly penetrate the patient's skin. The needle cover maintains the cannula in a substantially aseptic condition and enables self-administration by patients, such as young patients or needle adverse patients, which does not require their consciously inserting a needle into the skin.

摘要翻译： 具有独立存储的能量膜的流体输送装置，用于与基底结合限定流体储存器并且用于从储存器排出流体。 该装置包括新颖的储存器填充注射器和填充适配器，用于方便地填充装置的流体储存器。 此外，该装置包括独特的可压溃或可折叠的针罩，其围绕并保护输注套管直到使用时间，并且随着装置连接到患者而容易地变形，从而允许针干净地穿透患者的皮肤。 针盖将插管保持在基本上无菌的状态，并且能够使患者（例如年轻患者或针头不利患者）自行管理，这不需要有意识地将针插入皮肤。

公开(公告)号：US5906592A

公开(公告)日：1999-05-25

申请号：US907564

申请日：1997-08-08

申请人： Marshall S. Kriesel ,  Farhad Kazemzadeh ,  Matthew B. Kriesel ,  William W. Feng ,  Steve C Barber ,  William J. Kluck

发明人： Marshall S. Kriesel ,  Farhad Kazemzadeh ,  Matthew B. Kriesel ,  William W. Feng ,  Steve C Barber ,  William J. Kluck

IPC分类号： A61M5/14 ,  A61M5/142 ,  A61M5/152 ,  A61M5/158 ,  A61M37/00

CPC分类号： A61M5/1409 ,  A61M5/1413 ,  A61M5/14248 ,  A61M5/152 ,  A61M2005/1581 ,  A61M2205/197 ,  A61M5/1407 ,  Y10S128/12

摘要： An apparatus for accurately infusing fluids into a patient at specific rates over an extended period of time and the method for making same. The apparatus includes one or more dispensers of a low profile, laminate or layered construction each having a stored energy source in the form of a distendable membrane or an elastomeric cellular mass, which in cooperation with the base, defined a fluid chamber having a fluid inlet and a fluid outlet. The apparatus further includes, in lieu of a rigid ullage, a high novel, conformable ullage made of yieldable materials. The conformable ullage uniquely conforms to the shape of elastomeric membrane as the membrane returns to its less distended configuration. This arrangement will satisfy even the most stringent delivery tolerance requirements and will elegantly overcome the limitations of materials selection encountered in devices embodying the rigid ullage construction. Additionally, with the novel ullage construction, the ullage can be located either between the base and the fluid to be delivered, or alternatively, can be located between the elastomeric membrane and the fluid to be delivered. Further, a plurality of subreservoirs can be associated with a single ullage thereby making it possible to incorporate a wide variety of delivery profiles within a single device.

摘要翻译： 一种用于在更长时间内以特定速率准确地将流体注入患者体内的装置及其制造方法。 该设备包括一个或多个低分布，层压或分层结构的分配器，每个分配器具有可膨胀膜或弹性体泡沫体形式的储存能源，其与基底配合，限定了具有流体入口 和流体出口。 该装置还包括代替刚性缺损的由可屈服材料制成的高度新颖的，适合的缺口。 随着膜返回到较少膨胀的构型，适形的填充与弹性膜的形状完全一致。 这种布置将满足最严格的交货公差要求，并且将优雅地克服在体现刚性空间结构的装置中遇到的材料选择的限制。 另外，随着新颖的空白结构，空白可以位于基底和要输送的流体之间，或者可以位于弹性膜和要输送的流体之间。 此外，多个子储存器可以与单个空白相关联，从而使得可以在单个装置内并入多种递送曲线。

公开(公告)号：US5776103A

公开(公告)日：1998-07-07

申请号：US541184

申请日：1995-10-11

申请人： Marshall S. Kriesel ,  Farhad Kazemzadeh ,  Matthew B. Kriesel ,  William W. Feng ,  Steve C. Barber ,  William J. Kluck

发明人： Marshall S. Kriesel ,  Farhad Kazemzadeh ,  Matthew B. Kriesel ,  William W. Feng ,  Steve C. Barber ,  William J. Kluck

IPC分类号： A61M5/142 ,  A61M5/145 ,  A61M5/152 ,  A61M5/158 ,  A61M31/00 ,  A61M37/00

CPC分类号： A61M5/158 ,  A61M31/002 ,  A61M5/152 ,  A61M2005/14513 ,  A61M2005/1581 ,  A61M2205/197 ,  A61M2209/045 ,  A61M5/14248 ,  Y10S128/12

摘要： An apparatus for accurately infusing fluids into a patient at specific rates over an extended period of time. The apparatus is of a low profile, laminate or layered construction having a stored energy source in the form of a distendable membrane, which, in cooperation with the base of the apparatus, defines one or more fluid reservoirs, each having a fluid inlet and a fluid outlet. The apparatus further includes, a novel, conformable ullage made of yieldable materials which uniquely conforms to the shape of the elastomeric membrane as the membrane returns to its less distended configuration. This arrangement will satisfy even the most stringent medicament delivery tolerance requirements and will elegantly overcome the limitations of materials selection encountered in devices embodying solely a rigid ullage construction. Additionally, in one form of the invention, the infusion cannula of the apparatus is connected to the base of the apparatus in a novel manner which permits expeditious subdermal delivery of liquid medicaments to the patient via a cannula which extends generally perpendicularly from the base.

摘要翻译： 一种用于在较长时间内以特定速率准确地将流体输入患者体内的装置。 该装置具有薄型，层压或分层结构，其具有可膨胀膜形式的储存能量源，其与装置的底部协作限定一个或多个流体储存器，每个具有流体入口和 流体出口。 该装置还包括一种由可屈服材料制成的新颖的，顺应性的填充物，当薄膜返回到其较不膨胀的构型时，其完全符合弹性体膜的形状。 这种布置将满足甚至最严格的药物输送公差要求，并且将优雅地克服仅体现在刚性结构构造的装置中遇到的材料选择的限制。 另外，在本发明的一种形式中，该设备的输液插管以新颖的方式连接到设备的底座上，该新颖方式允许液体药物通过大体上垂直于基部垂直延伸的套管迅速向皮肤递送液体药物。