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公开(公告)号:US10398890B2
公开(公告)日:2019-09-03
申请号:US14331283
申请日:2014-07-15
Applicant: MEDTRONIC, INC.
Inventor: Martin T. Gerber , Michael D. Baudino
Abstract: Leads having distal electrodes may be used in application of test stimulation for purposes of implanting a lead having a fixation element distal to an electrode array. The fixation element is proximal the distal electrode. Accordingly, the distal electrode may be advanced beyond a distal end of an introducer while the fixation element may be retained in a retracted configuration by the introducer. If the test signals applied by the distal electrode indicate that the distal electrode is in the desired location of the patient, a series of markings on the lead may be used to facilitate placement of the electrode array at the location previously occupied by the distal electrode; i.e. the desired location of the patient. The electrodes of the electrode array may then be used to provide therapy to the patient.
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公开(公告)号:US10357757B2
公开(公告)日:2019-07-23
申请号:US14645394
申请日:2015-03-11
Applicant: Medtronic, Inc.
Inventor: Martin T. Gerber , Christopher M. Hobot
Abstract: A stacked sorbent assembly for use in sorbent dialysis. The stacked sorbent assembly contains two or more interchangeable sorbent pouches that allow for fluid to freely pass into and through the sorbent materials, while keeping the sorbent materials inside the sorbent pouches. Any of the pouches in the sorbent cartridge can be reused and/or recharged.
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公开(公告)号:US20190134289A1
公开(公告)日:2019-05-09
申请号:US16148218
申请日:2018-10-01
Applicant: Medtronic, Inc.
Inventor: Bryant J. Pudil , Martin T. Gerber , Christopher M. Hobot
IPC: A61M1/16
Abstract: The invention relates to systems and methods for performing dialysis with closed-loop control of sodium and bicarbonate concentrations in the dialysate. The system and methods can use one or more conductivity sensors in a dialysate flow path to determine a water addition rate and a bicarbonate addition rate resulting in a dialysate having desired sodium and bicarbonate concentrations.
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公开(公告)号:US20190134288A1
公开(公告)日:2019-05-09
申请号:US16240831
申请日:2019-01-07
Applicant: Medtronic, Inc.
Inventor: Orhan Soykan , VenKatesh R. Manda , Martin T. Gerber , Christopher M. Hobot
IPC: A61M1/16 , A61B5/0452 , A61B5/145 , A61M1/14 , A61B5/0205 , A61B5/0402
Abstract: A medical monitoring device for monitoring electrical signals from the body of a subject is described. The medical monitoring device monitors electrical signals originating from a cardiac cycle of the subject and associates each cardiac cycle with a time index. The medical monitoring device applies a forward computational procedure to generate a risk score indicative of hyperkalemia, hypokalemia or arrhythmia of the subject. The medical monitoring device can adjust the forward computational procedure based upon clinical data obtained from the subject.
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公开(公告)号:US10245365B2
公开(公告)日:2019-04-02
申请号:US16003245
申请日:2018-06-08
Applicant: Medtronic, Inc.
Inventor: Martin T. Gerber , Christopher M. Hobot
Abstract: An apparatus and method for replenishing urease in a sorbent cartridge for use in sorbent dialysis. The sorbent cartridge is configured to allow an amount of urease to be added to the sorbent cartridge. A urease solution can be injected into the sorbent cartridge to replenish the urease containing module, or solid urease can be added to the sorbent cartridge. The sorbent module can also comprise other, rechargeable, sorbent materials for removing toxins other than urea from spent dialysate.
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公开(公告)号:US10207041B2
公开(公告)日:2019-02-19
申请号:US15263582
申请日:2016-09-13
Applicant: Medtronic, Inc.
Inventor: Orhan Soykan , VenKatesh R. Manda , Martin T. Gerber , Christopher M. Hobot
IPC: A61B5/0205 , A61B5/0452 , A61M1/16 , A61B5/0402 , A61B5/145 , A61M1/14 , A61B5/04 , A61B5/00
Abstract: A medical monitoring device for monitoring electrical signals from the body of a subject is described. The medical monitoring device monitors electrical signals originating from a cardiac cycle of the subject and associates each cardiac cycle with a time index. The medical monitoring device applies a forward computational procedure to generate a risk score indicative of hyperkalemia, hypokalemia or arrhythmia of the subject. The medical monitoring device can adjust the forward computational procedure based upon clinical data obtained from the subject.
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公开(公告)号:US20180289880A1
公开(公告)日:2018-10-11
申请号:US16003245
申请日:2018-06-08
Applicant: Medtronic, Inc.
Inventor: Martin T. Gerber , Christopher M. Hobot
IPC: A61M1/16
CPC classification number: A61M1/1696
Abstract: An apparatus and method for replenishing urease in a sorbent cartridge for use in sorbent dialysis. The sorbent cartridge is configured to allow an amount of urease to be added to the sorbent cartridge. A urease solution can be injected into the sorbent cartridge to replenish the urease containing module, or solid urease can be added to the sorbent cartridge. The sorbent module can also comprise other, rechargeable, sorbent materials for removing toxins other than urea from spent dialysate.
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公开(公告)号:US10071323B2
公开(公告)日:2018-09-11
申请号:US14626281
申请日:2015-02-19
Applicant: MEDTRONIC, INC
Inventor: Bryant J. Pudil , Martin T. Gerber , David B. Lura , Thomas E. Meyer
CPC classification number: B01D15/203 , A61M1/1621 , A61M1/1696 , A61M1/367 , A61M2202/0468 , A61M2205/128 , A61M2205/3334 , B01D15/10 , B01J20/3416 , B01J20/3425 , B01J20/3433 , B01J20/3475 , B01J2220/62
Abstract: This disclosure generally relates to at least one reusable module of a sorbent cartridge in a sorbent dialysis system and a method of using the same. One of the drawbacks of a conventional sorbent dialysis system is the high cost. In one aspect of the invention, the sorbent cartridge contains at least one module for optionally recharging sorbent materials in-line with an optional bypass and conduits for the sorbent cartridge. The sorbent cartridge can have two or more modules that are connected to one another through connectors. The modules can be reusable and the sorbent materials contained in the modules can be recharged.
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公开(公告)号:US10046164B2
公开(公告)日:2018-08-14
申请号:US13968290
申请日:2013-08-15
Applicant: Medtronic, Inc.
Inventor: Martin T. Gerber
Abstract: In some examples, a chronic implantable neurostimulator supports trial and chronic modes of operation. In addition, in some examples, the neurostimulator can alternatively include one or more sensors that may or may not function differently in trial and chronic modes. The device may be designed to be used as both a trial neurostimulator and a permanent, or chronic, neurostimulator. A trial neurostimulation period can be used to evaluate the efficacy of the therapy. A percutaneous or implantable trial neurostimulator is used for the trial neurostimulation period. In most cases, the trial period is successful, in which case the trial stimulator is explanted and replaced with a permanent, i.e., “chronic,” implantable stimulator. In accordance with the disclosure, an implantable neurostimulator supports both trial neurostimulation and chronic neurostimulation in the event trial stimulation is successful.
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公开(公告)号:US20180193546A1
公开(公告)日:2018-07-12
申请号:US15914791
申请日:2018-03-07
Applicant: Medtronic, Inc.
Inventor: Martin T. Gerber , Christopher M. Hobot
CPC classification number: A61M1/28 , A61B5/14507 , A61B5/6866 , A61M1/1601 , A61M1/1609 , A61M1/287 , A61M2205/3306 , A61M2205/3324 , A61M2205/50 , A61M2205/75 , G01N21/78 , G01N21/80 , G01N2021/7773 , G01N2021/7783 , G01N2021/7786 , G01N2800/06
Abstract: The invention relates to a testing system and related methods for detecting peritonitis or infection in peritoneal dialysate removed from a patient. The testing system can include a fluid sensor apparatus in a fluid line of a peritoneal dialysis cycler through which spent peritoneal dialysate can be pumped. The fluid sensor apparatus can detect one or more markers associated with peritonitis or infection.
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