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公开(公告)号:US10667754B2
公开(公告)日:2020-06-02
申请号:US16163661
申请日:2018-10-18
Inventor: Peter Starr , Steven Bailey , Mauli Agrawal
IPC: G01L9/00 , A61B5/00 , A61B5/0215 , A61B5/103 , A61M1/10 , A61B5/1473 , A61B7/02 , A61F2/24 , B29C65/48 , A61B5/145 , A61B17/00 , A61M1/12 , A61B5/03 , B29L31/00
Abstract: A thin-film, diaphragm based device is disclosed which can be used to perform an array of sensing and actuating operations where a very thin profile is desired, such as in millimeter, micrometer, or nanometer tight spaces.
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132.
公开(公告)号:US10660586B2
公开(公告)日:2020-05-26
申请号:US16443360
申请日:2019-06-17
Inventor: Hak Choy , Steve Jiang , Robert Timmerman , Arnold Pompos
Abstract: Radiation therapy systems and their components, including secondary radiation shields. At least some versions of the disclosed systems combine a radiation delivery device, a primary radiation shielding device, and a secondary shielding layer into an integrated, modular unit. This is accomplished by using a small direct beam shield capable of blocking a primary beam from a radiation delivery device. In turn, a thinner shielding layer can be used to surround the radiation delivery device and primary shielding device, enabling a single modular unit to be delivered to an installation site. In some embodiments, a bed may be disposed within the secondary shielding layer. In some embodiments, the system is configured to provide up to 4-pi (4π) steradians of radiation coverage to the bed from the radiation delivery device.
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公开(公告)号:US20200147151A1
公开(公告)日:2020-05-14
申请号:US16481187
申请日:2018-01-30
Inventor: Herbert L. DUPONT , Zhi-Dong JIANG
IPC: A61K35/742 , A61K47/26
Abstract: The present disclosure provides human fecal microbiota compositions, including fresh, frozen, and lyophilized compositions, for the treatment of disorders associated with dysfunctional microbiota, such as recurrent Clostridium difficile infection. In particular, the fecal microbiota composition comprises a cryoprotectant sugar, such as mannitol.
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公开(公告)号:US20200087451A1
公开(公告)日:2020-03-19
申请号:US16570337
申请日:2019-09-13
Inventor: Jinming GAO , Gang HUANG , Tian ZHAO , Baran D. SUMER , Xiankai SUN
Abstract: The present disclosure relates to polymers which contain a hydrophobic and hydrophilic segment which is sensitive to pH as well as a metal chelating group. In some aspects, the metal chelating group is chelated to a metal ion capable of positron emission. In some aspects, the polymers form a micelle which is sensitive to pH and results in a change in fluorescence based upon the particular pH. In some aspects, the disclosure also provides methods of using the polymers for the imaging of cellular or extracellular environment or delivering a drug.
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公开(公告)号:US10589096B2
公开(公告)日:2020-03-17
申请号:US15496444
申请日:2017-04-25
Inventor: Nitin Tandon
Abstract: This invention relates generally to systems and methods for multifocal direct brain stimulation to enhance cognitive processing, such as but not limited to stimulation-induced modulation of memory.
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136.
公开(公告)号:US20200078395A1
公开(公告)日:2020-03-12
申请号:US16563439
申请日:2019-09-06
Inventor: Charles Y.C. PAK , Khashayar SAKHAEE , Orson W. MOE
Abstract: Disclosed is the use of an effervescent preparation of calcium and magnesium with additional citric acid in a defined ratio to reduce serum C-carboxy-terminal telopeptide (CTX), increase urinary Mg, increase FEMg, increase urinary citrate, reduce urinary ammonium, and decrease putative serum fibroblast growth factor 23 (FGF23) in subjects taking proton pump inhibitors.
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公开(公告)号:US10578763B2
公开(公告)日:2020-03-03
申请号:US15818911
申请日:2017-11-21
Inventor: Jeffrey Gabelmann , Mark Allen Oerkfitz , Thomas David Hosbach , Mukul M. Sharma , Ali Yilmaz , Carlos Torres-Verdin
Abstract: Systems and methods for assessing physical properties of a geological formation are disclosed. The systems and methods may use electrodes that include two conductive portions separated by an isolation gap positioned along a casing in a wellbore in the formation. The electrodes may be sequentially energized to provide excitation stimulus into the formation while the remaining, non-energized electrodes may substantially simultaneously receive excitation responses to the excitation stimulus from the formation. The excitation responses may be assessed to determine one or more physical properties of fractures in the formation.
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公开(公告)号:US10576284B2
公开(公告)日:2020-03-03
申请号:US15590590
申请日:2017-05-09
Inventor: Dane W Grasse , Robert L Rennaker, II
Abstract: Systems and methods for stimulating tissue. Exemplary embodiments include systems and methods configured to maintain one electrode at a fixed voltage potential and switching a second electrode between different fixed voltage potentials.
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公开(公告)号:US20200055954A1
公开(公告)日:2020-02-20
申请号:US16441350
申请日:2019-06-14
Inventor: Ningyan ZHANG , Zhiqiang AN
IPC: C07K16/32 , G01N33/574 , A61N5/10 , A61K45/06 , A61K39/395 , A61F7/10
Abstract: Isolated or recombinant anti-HER3 monoclonal antibodies are provided. In some cases, antibodies of the embodiments can be used for the detection, diagnosis and/or therapeutic treatment of human diseases, such as cancer.
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公开(公告)号:US20200046751A1
公开(公告)日:2020-02-13
申请号:US16353737
申请日:2019-03-14
Inventor: William S. Korinek , James D. Lechleiter , Theodore E. Liston
IPC: A61K31/7076 , A61K31/52
Abstract: The present invention relates to compounds and methods of use thereof for treatment of certain disorders and conditions, for example brain injuries such as stroke or traumatic brain injuries.
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