公开(公告)号：US10550401B2

公开(公告)日：2020-02-04

申请号：US15802843

申请日：2017-11-03

Applicant: Monsanto Technology LLC

Inventor： Stanislaw Flasinski ,  Barrett C. Foat ,  Mohammed Oufattole ,  Randall W. Shultz ,  Xiaoping Wei ,  Wei Wu ,  Shiaw-Pyng Yang

IPC: C12N15/82

Abstract: The invention provides DNA molecules and constructs, including their nucleotide sequences, useful for modulating gene expression in plants and plant cells. Transgenic plants, plant cells, plant parts, seeds, and commodity products comprising the DNA molecules operably linked to heterologous transcribable polynucleotides are also provided, as are methods of their use.

公开(公告)号：US10457958B2

公开(公告)日：2019-10-29

申请号：US16047187

申请日：2018-07-27

Applicant: Monsanto Technology LLC

Inventor： James A. Baum ,  Thomas Cerruti ,  Stanislaw Flasinski ,  Xiaoran Fu ,  Arlene R. Howe ,  Sara Ann Salvador

IPC: C12N15/82 ,  C07K14/325 ,  A01N47/08 ,  A01N63/02

Abstract: Engineered Cry1Da amino acid sequences are provided that exhibit improved Lepidopteran insecticidal activity and an enhanced Lepidopteran spectrum compared to the naturally occurring Cry1Da protein toxin. Polynucleotide sequences intended for use in expression of the improved proteins in plants are also provided. Particular embodiments provide compositions containing insect inhibitory amounts of the engineered proteins, as well as recombinant plants, plant parts, and seeds containing polynucleotide constructs encoding one or more of the improved engineered proteins.

公开(公告)号：US20190323028A1

公开(公告)日：2019-10-24

申请号：US16404513

申请日：2019-05-06

Applicant: Monsanto Technology LLC

Inventor： Wen C. Burns ,  Catherine A. Chay ,  Cheryl L. Cloninger ,  Mingqi Deng ,  Stanislaw Flasinski ,  Kunsheng Wu

IPC: C12N15/82

Abstract: The invention provides corn event MON 87411, and plants, plant cells, seeds, plant parts, and commodity products comprising event MON 87411. The invention also provides polynucleotides specific for event MON 87411 and plants, plant cells, seeds, plant parts, and commodity products comprising polynucleotides specific for event MON 87411. The invention also provides methods related to event MON 87411.

公开(公告)号：US20190249190A1

公开(公告)日：2019-08-15

申请号：US16391748

申请日：2019-04-23

Applicant: Monsanto Technology LLC

Inventor： David J. Bowen ,  Catherine Chay ,  Artem Evdokimov ,  Stanislaw Flasinski ,  Uma R. Kesanapalli ,  Megan N. Schroder ,  Rachael N. Slightom ,  Nengbing Tao ,  Andrew M. Wollacott

IPC: C12N15/82 ,  C07K14/32

Abstract: The present invention discloses a genus of insect inhibitory proteins that exhibit properties directed to controlling Lepidopteran and/or Hemipteran crop pests, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.

公开(公告)号：US10316331B2

公开(公告)日：2019-06-11

申请号：US15486804

申请日：2017-04-13

Applicant: Monsanto Technology LLC

Inventor： David J. Bowen ,  Catherine Chay ,  Artem Evdokimov ,  Stanislaw Flasinski ,  Uma R. Kesanapalli ,  Megan N. Schroder ,  Rachael N. Slightom ,  Nengbing Tao ,  Andrew M. Wollacott

IPC: C07K14/32 ,  C12N15/82 ,  A01H5/00

Abstract: The present invention discloses a genus of insect inhibitory proteins that exhibit properties directed to controlling Lepidopteran and/or Hemipteran crop pests, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.

公开(公告)号：US20180291395A1

公开(公告)日：2018-10-11

申请号：US15944114

申请日：2018-04-03

Applicant: MONSANTO TECHNOLOGY LLC

Inventor： David J. Bowen ,  Catherine A. Chay ,  Todd A. Ciche ,  Stanislaw Flasinski ,  Arlene R. Howe ,  Krishnakumar Sridharan

IPC: C12N15/82 ,  C07K14/415 ,  C07K14/47 ,  C07K14/32 ,  C07K14/245 ,  C07K14/27 ,  C07K14/26

Abstract: A pesticidal protein class exhibiting toxic activity against Coleopteran and Lepidopteran pest species is disclosed, and includes, but is not limited to, TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Coleopteran and Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using the TIC7040, TIC7042, TIC7381, TIC7382, TIC7383, TIC7386, TIC7388, and TIC7389 pesticidal proteins are also provided.

公开(公告)号：US10017549B2

公开(公告)日：2018-07-10

申请号：US13950439

申请日：2013-07-25

Applicant: Monsanto Technology LLC

Inventor： James A. Baum ,  Stanislaw Flasinski ,  Gregory R. Heck ,  Stephen R. Penn ,  Uma Rao Sukuru ,  Xiaohong Shi

IPC: C07K14/325 ,  A01N63/00 ,  C12N15/82

CPC classification number: C07K14/325 ,  A01N63/00 ,  C12N15/8286 ,  Y02A40/162

Abstract: A novel Bacillus thuringiensis crystal protein exhibiting insect inhibitory activity is disclosed. Growth of Lygus insects is significantly inhibited by providing the novel crystal protein in Lygus insect diet. Polynucleotides encoding the crystal protein, transgenic plants and microorganisms that contain the polynucleotides, isolated peptides derived from the crystal protein, and antibodies directed against the crystal protein are also provided. Methods of using the crystal protein and polynucleotides encoding the crystal protein to control Hemipteran insects are also disclosed.

公开(公告)号：US20180127772A1

公开(公告)日：2018-05-10

申请号：US15848837

申请日：2017-12-20

Applicant: Monsanto Technology LLC

Inventor： James A. Baum ,  Thomas A. Cerruti ,  Crystal L. Dart ,  Leigh H. English ,  Stanislaw Flasinski ,  Xiaoran Fu ,  Victor M. Guzov ,  Arlene R. Howe ,  Jay P. Morgenstern ,  James K. Roberts ,  Sara A. Salvador ,  Jinling Wang

IPC: C12N15/82

CPC classification number: C07K14/325 ,  A01N63/02 ,  C07K2319/00 ,  C12N15/62 ,  C12N15/8286 ,  Y02A40/162

Abstract: Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.

公开(公告)号：US09951347B2

公开(公告)日：2018-04-24

申请号：US15046914

申请日：2016-02-18

Applicant: Monsanto Technology LLC

Inventor： Stanislaw Flasinski

IPC: C12N15/82

CPC classification number: C12N15/8216 ,  C12N15/8279

Abstract: The invention provides novel recombinant DNA molecules and constructs useful for modulating gene expression in plants, plant cells, seeds, and progeny plants. Plant regulatory elements comprising sequences from the Ubq10 gene of C. lacryma-jobi, as well as variants and fragments thereof having gene regulatory activity, are provided. The invention also provides transgenic plants, plant cells, plant parts, seeds, and progeny plants comprising the recombinant DNA molecules of the invention, along with methods of their use.

公开(公告)号：US20180057833A1

公开(公告)日：2018-03-01

申请号：US15668668

申请日：2017-08-03

Applicant: Monsanto Technology LLC

Inventor： Stanislaw Flasinski

IPC: C12N15/82 ,  C07K14/415 ,  C12N15/113 ,  C12N15/11

CPC classification number: C12N15/8216 ,  C07K14/415 ,  C12N15/11 ,  C12N15/113 ,  C12N15/8201 ,  C12N15/8222 ,  C12N15/8225 ,  C12N15/8227 ,  C12N15/8231 ,  C12N15/8234 ,  C12N15/8241 ,  C12N15/8261 ,  C12N15/8274 ,  C12N15/8279

Abstract: The present invention provides novel DNA molecules and constructs, including their nucleotide sequences, useful for modulating gene expression in plants and plant cells. The invention also provides transgenic plants, plant cells, plant parts, seeds, and commodity products comprising the DNA molecules operably linked to heterologous transcribable polynucleotides, along with methods of their use.