中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

420 records (took 0.039 seconds)

    (E)-styryl sulfone anticancer agents
    167.
    发明申请
    (E)-styryl sulfone anticancer agents 有权
    （E） - 苯乙烯基砜抗癌剂

    公开(公告)号：US20030216535A1

    公开(公告)日：2003-11-20

    申请号：US10462919

    申请日：2003-06-16

    Applicant: Temple University - Of The Commonwealth System of Higher Education

    Inventor： E. Premkumar Reddy ,  M.V. Ramana Reddy

    IPC: C08F128/02 ,  C07C317/24

    CPC classification number: C07C317/18 ,  C07C317/10 ,  C07C317/44

    Abstract: (E)-styryl benzylsulfones of formula I are useful as anticancer agents: 1 wherein R1, R2, R3, and R4 are independently selected from the group consisting of hydrogen, fluoro, chloro, iodo, bromo, C1-C6 alkyl, C1-C4 alkoxy, nitro, cyano and trifluoromethyl, with the proviso that (a) R1, R2 , and R3 not all hydrogen when R4 is 2-chloro or 4-chloro; (b) when R1 and R3 are hydrogen and R2 is 4-bromo or 4-chloro, then R4 may not be 4-chloro, 4-fluoro or 4-bromo; (c) when R1 and R3 are hydrogen and R2 is 4-fluoro, then R4 may not be 4-fluoro or 4-bromo, (d) when R1 is hydrogen, and R4 is 2-fluoro, the R2 and R3 may not be 4-fluoro; and (e) when R1 is hydrogen and R3 is 4-hydrogen, 4-chloro, 4-bromo, 4-methyl or 4-methoxy, and R4 is 2-hydrogen, 2-chloro, or 2-fluoro; then R2 may not be 4-hydrogen, 4-chloro, 4-fluoro, or 4-bromo.

    Abstract translation: 式I的（E） - 苯乙烯基苄基砜可用作抗癌剂：其中R 1，R 2，R 3和R 4独立地选自氢，氟，氯，碘，溴，C 1 -C 6烷基，C 1 -C 4 烷氧基，硝基，氰基和三氟甲基，条件是（a）当R 4为2-氯或4-氯时，R 1，R 2和R 3不全部为氢; （b）当R 1和R 3为氢且R 2为4-溴或4-氯时，R 4可为4-氯，4-氟或4-溴; （c）当R 1和R 3为氢且R 2为4-氟时，R 4可以不是4-氟或4-溴，（d）当R 1为氢，R 4为2-氟时，R 2和R 3可为 为4-氟; 和（e）当R 1为氢且R 3为4-氢，4-氯，4-溴，4-甲基或4-甲氧基时，R 4为2-氢，2-氯或2-氟; 那么R 2可以不是4-氢，4-氯，4-氟或4-溴。

    Method and apparatus for increasing and modulating the yield shear stress of electrorheological fluids
    168.
    发明申请
    Method and apparatus for increasing and modulating the yield shear stress of electrorheological fluids 有权
    用于增加和调节电流变流体的屈服剪切应力的方法和装置

    公开(公告)号：US20030089596A1

    公开(公告)日：2003-05-15

    申请号：US10007575

    申请日：2001-11-09

    Applicant: Temple University of the Commonwealth System of Higher Education

    Inventor： Rongjia Tao ,  Yucheng Lan ,  Xiaojun Xu ,  Edward Kaczanowicz

    IPC: B01J019/08

    CPC classification number: F16F9/532 ,  C10M171/001 ,  C10N2240/20 ,  F15B21/065

    Abstract: A method for increasing and/or modulating the yield shear stress of an electrorheological fluid includes applying a sufficient electric field to the fluid to cause the formation of chains of particles, and then applying a sufficient pressure to the fluid to cause thickening or aggregation of the chains. An apparatus for increasing and/or modulating the transfer or force or torque between two working structures includes an electrorheological fluid and electrodes through which an electric field is applied to the fluid such that particles chains of particles are formed in the fluid and, upon application of pressure to the fluid, the chains thicken or aggregate and improve the force or torque transmission.

    Abstract translation: 用于增加和/或调节电流变流体的屈服剪切应力的方法包括向流体施加足够的电场以引起颗粒链的形成，然后向流体施加足够的压力以引起增稠或聚集 链条 用于增加和/或调节两个工作结构之间的转移或力或扭矩的装置包括电流变流体和电极，通过电极将电场施加到流体上，使得粒子的颗粒链在流体中形成，并且在应用 对流体的压力，链条增厚或聚集，并改善力或扭矩传递。

Patent Agency Ranking