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    INTEGRATED HYBRID HEART VALVES
    162.
    发明申请
    INTEGRATED HYBRID HEART VALVES 审中-公开
    集成杂交心脏瓣膜

    公开(公告)号：US20170000604A1

    公开(公告)日：2017-01-05

    申请号：US15199748

    申请日：2016-06-30

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin ,  Qinggang Zeng ,  Myron Howanec, JR. ,  Grace Myong Kim

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2210/0057 ,  A61F2220/0075 ,  A61F2230/0069 ,  A61F2250/001 ,  A61F2250/0018 ,  A61F2250/0048 ,  A61F2250/006 ,  A61F2250/0097

    Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander. An inflow stent frame is expandable for anchoring the valve in place, and may have an outflow end that is collapsible to a limited degree for delivery and expandable post-implant to facilitate a valve-in-valve (ViV) procedure. The hybrid heart valves eliminate earlier structural bands, which both reduces manufacturing time and facilitates a ViV procedure.

    Abstract translation: 公开了一种假体心脏瓣膜，其构造成替代原生心脏瓣膜并且具有构造成重新成形为膨胀形式以支撑可膨胀假体心脏瓣膜和/或支撑其中的可扩张假体心脏瓣膜的支撑框架及其使用方法。 假体心脏瓣膜可以被构造成当最初植入时具有大致刚性和/或抗膨胀的构造，以替代天然瓣膜（或其他假体心脏瓣膜），但是当受到向外的力（例如， 由膨胀气球或其他机械膨胀机提供。 流入支架框架是可扩张的，用于将阀固定在适当位置，并且可以具有在有限程度上可折叠的流出端，用于输送和可扩展的植入后可促进阀门（ViV）程序。 混合心脏瓣膜消除了早期的结构带，这既减少了制造时间又促进了ViV程序。

    Cardiac implant with integrated suture fasteners
    163.
    发明授权
    Cardiac implant with integrated suture fasteners 有权
    心脏植入物与综合缝合紧固件

    公开(公告)号：US09468527B2

    公开(公告)日：2016-10-18

    申请号：US14302733

    申请日：2014-06-12

    Applicant: Edwards Lifesciences Corporation

    Inventor： Salvador Marquez ,  Brian S. Conklin ,  Manouchehr A. Miraki ,  Yoon H. Kwon

    IPC: A61F2/24 ,  A61B17/04

    CPC classification number: A61F2/2445 ,  A61B17/02 ,  A61B17/0487 ,  A61B2017/0237 ,  A61B2017/0488 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2448

    Abstract: A cardiac implant system including a cardiac implant such as an annuloplasty ring, a prosthetic heart valve, or a valved conduit pre-assembled at the time of manufacture with devices for securing the implant to a heart valve annulus using knotless suture fasteners. The knotless suture fasteners may be embedded within a pliant sealing edge of the cardiac implant, or they may be positioned adjacent to the sealing edge. The knotless suture fasteners are spring-biased so as to grip onto annulus anchoring sutures pass to therethrough upon removal of a restraining device, such as a hypotube inserted within the suture fasteners. Guide tubes are assembled in line with the suture fasteners to permit introduction of suture snares that pass through the suture fasteners and through the sealing edge to facilitate capture of the pre-installed annulus anchoring sutures.

    Abstract translation: 一种心脏植入系统，其包括心脏植入物，例如瓣膜成形术环，假体心脏瓣膜或在制造时预先组装的带阀的导管，其中装置使用无缝缝合紧固件将植入物固定到心脏瓣膜环。 无缝缝合紧固件可以嵌入在心脏植入物的柔性密封边缘内，或者它们可以邻近密封边缘定位。 无缝缝合紧固件被弹簧偏置，以便在去除限制装置（例如插入缝合线紧固件内的海波管）时夹紧到环形锚固缝合线上。 引导管与缝合线紧固件一起组装，以允许引入通过缝合线紧固件并穿过密封边缘的缝合线圈，以便于捕获预先安装的环形锚定缝合线。

    DYNAMIC ANNULOPLASTY RING SIZER
    167.
    发明申请
    DYNAMIC ANNULOPLASTY RING SIZER 有权
    动态ANNULOPLASTY戒指大小

    公开(公告)号：US20160015518A1

    公开(公告)日：2016-01-21

    申请号：US14867992

    申请日：2015-09-28

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin

    IPC: A61F2/24

    CPC classification number: A61F2/2496 ,  A61B5/107 ,  A61B5/1076 ,  A61B5/6852 ,  A61B5/6869 ,  A61B90/06 ,  A61B2090/0807 ,  A61F2/2445 ,  A61F2/2472 ,  A61F2250/001 ,  A61F2250/0097

    Abstract: A dynamic, adjustable annuloplasty ring sizer can include an adjustable ring replica, which can be adjusted through a range of sizes corresponding to available prosthetic annuloplasty repair ring sizes. Actuation of an adjustment trigger on a handle portion of the ring sizer can displace tension wires that extend through a malleable shaft and through a plurality of articulating segments that form the ring replica. Displacement of the tension wires causes flexion of the joints between adjacent articulating segments, thereby reducing the overall size of the ring replica. Releasing the tension wires can allow an elastic extension wire to act on the ring replica, enlarging the ring replica to its maximum, at-rest size. In this manner, the appropriate size of annuloplasty ring prosthesis can be determined with a single device, without requiring a plurality of static ring sizers that require individual insertion and placement for the conventional trial-and-error sizing methods.

    Abstract translation: 动态，可调节瓣环成形术环形筛分器可以包括可调整的环形复制件，其可以通过对应于可用的假体瓣环成形术修复环尺寸的一系列尺寸进行调整。 在环形筛分机的手柄部分上的调节触发器的致动器可以移动延伸穿过可延展的轴并通过形成环形复制件的多个铰接段的张力线。 张力线的位移导致相邻铰接段之间的接头弯曲，从而减小环形复制体的总体尺寸。 释放张力线可以允许弹性延伸线作用在环形复制品上，将环形复制品放大到最大静止尺寸。 以这种方式，可以使用单个装置来确定瓣环成形术假体的适当尺寸，而不需要多个静态环形筛分器，其需要单独的插入和放置用于常规的试验和误差尺寸测量方法。

    COVERED HEART VALVE SIZER
    168.
    发明申请
    COVERED HEART VALVE SIZER 有权
    覆盖心脏瓣膜

    公开(公告)号：US20150005671A1

    公开(公告)日：2015-01-01

    申请号：US14315649

    申请日：2014-06-26

    Applicant: Edwards Lifesciences Corporation

    Inventor： Gerald B. Gollinger ,  William A. Maywald ,  Derrick Johnson ,  Brian S. Conklin ,  Ankita Bordoloi ,  Da-Yu Chang

    IPC: A61F2/24 ,  A61B5/107

    CPC classification number: A61F2/2496 ,  A61B5/1076

    Abstract: A heart valve sizer and sizer cover are provided for determining the size of a heart valve annulus. The valve sizer can include a handle, a shaft extending distally from the handle, a sizing element coupled to the distal end of the shaft, the sizing element being movable between a first retracted position and a second expanded position, and a sizer cover. The sizer cover can be formed from a continuous sheet of material configured to surround at least a portion of the sizing element of the heart valve sizer so as to guard against entanglement of the sizing element with structures of a human heart.

    Abstract translation: 提供心脏瓣膜分流器和筛分器盖以确定心脏瓣膜环的尺寸。 阀门分级器可以包括手柄，从手柄向远侧延伸的轴，连接到轴的远端的定尺寸元件，该尺寸元件可在第一缩回位置和第二扩张位置之间移动，以及筛分器盖。 分级器盖可以由连续的材料片形成，其被配置为围绕心脏瓣膜分选器的施胶元件的至少一部分，以防止施胶元件与人心脏的结构的缠结。

    DYNAMIC ANNULOPLASTY RING SIZER
    169.
    发明申请
    DYNAMIC ANNULOPLASTY RING SIZER 有权
    动态ANNULOPLASTY戒指大小

    公开(公告)号：US20140277421A1

    公开(公告)日：2014-09-18

    申请号：US14187084

    申请日：2014-02-21

    Applicant: EDWARDS LIFESCIENCES CORPORATION

    Inventor： Brian S. Conklin

    IPC: A61F2/24

    CPC classification number: A61F2/2496 ,  A61B5/107 ,  A61B5/1076 ,  A61B5/6852 ,  A61B5/6869 ,  A61B90/06 ,  A61B2090/0807 ,  A61F2/2445 ,  A61F2/2472 ,  A61F2250/001 ,  A61F2250/0097

    Abstract: A dynamic, adjustable annuloplasty ring sizer can include an adjustable ring replica, which can be adjusted through a range of sizes corresponding to available prosthetic annuloplasty repair ring sizes. Actuation of an adjustment trigger on a handle portion of the ring sizer can displace tension wires that extend through a malleable shaft and through a plurality of articulating segments that form the ring replica. Displacement of the tension wires causes flexion of the joints between adjacent articulating segments, thereby reducing the overall size of the ring replica. Releasing the tension wires can allow an elastic extension wire to act on the ring replica, enlarging the ring replica to its maximum, at-rest size. In this manner, the appropriate size of annuloplasty ring prosthesis can be determined with a single device, without requiring a plurality of static ring sizers that require individual insertion and placement for the conventional trial-and-error sizing methods.

    Abstract translation: 动态，可调节瓣环成形术环形筛分器可以包括可调整的环形复制件，其可以通过对应于可用的假体瓣环成形术修复环尺寸的一系列尺寸进行调整。 在环形筛分机的手柄部分上的调节触发器的致动器可以移动延伸穿过可延展的轴并通过形成环形复制件的多个铰接段的张力线。 张力线的位移导致相邻铰接段之间的接头弯曲，从而减小环形复制体的总体尺寸。 释放张力线可以允许弹性延伸线作用在环形复制品上，将环形复制品放大到最大静止尺寸。 以这种方式，可以使用单个装置来确定瓣环成形术假体的适当尺寸，而不需要多个静态环形筛分器，其需要单独的插入和放置用于常规的试验和误差尺寸测量方法。

    SIDE-ENTRY KNOTLESS SUTURE ANCHORING CLAMPS AND DEPLOYMENT TOOLS
    170.
    发明申请
    SIDE-ENTRY KNOTLESS SUTURE ANCHORING CLAMPS AND DEPLOYMENT TOOLS 有权
    侧进式无缝安装夹具及配件工具

    公开(公告)号：US20130282028A1

    公开(公告)日：2013-10-24

    申请号：US13920983

    申请日：2013-06-18

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin ,  Louis A. Campbell ,  Salvador Marquez ,  Donald E. Bobo, Jr.

    IPC: A61B17/04

    CPC classification number: A61B17/0487 ,  A61B17/0401 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0414 ,  A61B2017/0416 ,  A61B2017/0464 ,  A61B2017/0488 ,  A61B2017/0496 ,  A61F2/24 ,  A61F2/2409 ,  A61F2/2442

    Abstract: Suture locking clamps for securing prostheses such as heart valves or annuloplasty rings with sutures and without knots improve the ease of implantation. The clamps have opposed clamp halves separated by a slot opening to one side and surrounded by a biasing member such as one or more C-clip springs. Sutures pass laterally into the slot which is held open by a retention member positioned between the clamp halves. The locking clamp slides along the sutures into position, the tension of the sutures is adjusted, and the retention member removed to allow the biasing member to clamp the sutures between the clamp halves. A delivery tool used to deliver and deploy the locking clamps contains a number of clamps within a delivery tube in a stack and bonded together for safety and a common retention member. The tool has a longitudinal channel on one side for entry of sutures.

    Abstract translation: 用于固定假体（例如心脏瓣膜或带有缝线和瓣环的瓣环成形术环）的缝合线锁定件提高了植入的容易性。 夹具具有相对的夹具半部，该半部由通向一侧的狭槽分开，并被诸如一个或多个C形夹弹簧的偏置构件包围。 缝合线横向穿过狭槽，狭槽由位于夹子半部之间的保持构件保持打开。 锁定夹具沿着缝合线滑动到适当位置，调节缝合线的张力，并且移除保持构件以允许偏置构件将缝合线夹在夹具半部之间。 用于传送和展开锁定夹具的输送工具在堆叠中的输送管内包含多个夹具，并且为了安全而将其粘合在一起并具有公共保持构件。 该工具在一侧具有用于进入缝合线的纵向通道。

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