公开(公告)号：US08208137B2

公开(公告)日：2012-06-26

申请号：US12696853

申请日：2010-01-29

Applicant: Min Hu ,  Alexandre M. Bratkovski ,  Jingjing Li ,  Huei Pei Kuo ,  Zhiyong Li ,  Fung Suong Ou ,  Michael Josef Stuke ,  Michael Renne Ty Tan ,  Shih-Yuan Wang ,  Wei Wu

Inventor： Min Hu ,  Alexandre M. Bratkovski ,  Jingjing Li ,  Huei Pei Kuo ,  Zhiyong Li ,  Fung Suong Ou ,  Michael Josef Stuke ,  Michael Renne Ty Tan ,  Shih-Yuan Wang ,  Wei Wu

IPC: G01J3/44

CPC classification number: G01J3/44

Abstract: An apparatus for detecting at least one molecule using Raman light detection includes a substrate for supporting a sample containing the at least one molecule, a laser source for emitting a laser beam to cause Raman light emission from the at least one molecule, a modulating element for modulating a spatial relationship between the laser beam and the substrate at an identified frequency to cause the Raman light to be emitted from the at least one molecule at the identified frequency, at least one detector for detecting the Raman light emitted from the at least one molecule, and a post-signal processing unit configured to process the detected Raman light emission at the identified frequency to detect the at least one molecule.

Abstract translation: 用于使用拉曼光检测检测至少一个分子的装置包括用于支撑含有至少一个分子的样品的基底，用于发射激光束以产生来自至少一个分子的拉曼光发射的激光源， 以识别的频率调制激光束和衬底之间的空间关系，以使所述拉曼光以所识别的频率从所述至少一个分子发射;至少一个检测器，用于检测从所述至少一个分子发射的拉曼光 以及后信号处理单元，被配置为处理所识别的频率处的所检测的拉曼光发射以检测所述至少一个分子。

公开(公告)号：US08207519B2

公开(公告)日：2012-06-26

申请号：US12763091

申请日：2010-04-19

Applicant: Janice H Nickel ,  Michael Renne Ty Tan ,  Zhiyong Li

Inventor： Janice H Nickel ,  Michael Renne Ty Tan ,  Zhiyong Li

IPC: H01L47/00 ,  H01L21/332 ,  G11C13/00

CPC classification number: H01L45/085 ,  H01L27/2463 ,  H01L45/1233 ,  H01L45/146

Abstract: A nanoscale switching device is provided, comprising: a first electrode of a nanoscale width; a second electrode of a nanoscale width; an active region disposed between the first and second electrodes, the active region having at least one non-conducting layer comprising an electronically semiconducting or nominally insulating and a weak ionic conductor switching material capable of carrying a species of dopants and transporting the dopants under an electric field; and a source layer interposed between the first electrode and the second electrode and comprising a highly reactive and highly mobile ionic species that reacts with a component in the switching material to create dopants that are capable of drifting through the non-conducting layer under an electric field, thereby controlling dopant profile by ionic modulation. A crossbar array comprising a plurality of the nanoscale switching devices is also provided, along with a process for making at least one nanoscale switching device.

Abstract translation: 提供一种纳米级切换装置，包括：纳米级宽度的第一电极; 纳米级宽度的第二电极; 有源区域，设置在第一和第二电极之间，有源区域具有至少一个非导电层，包括电子半导体或名义上绝缘的和弱离子导体开关材料，能够携带一种掺杂剂并在电气下传输掺杂剂 领域; 以及插入在所述第一电极和所述第二电极之间的源极层，并且包括高反应性和高度移动的离子物质，其与所述开关材料中的组分反应以产生能够在电场下漂移通过所述非导电层的掺杂剂 ，从而通过离子调制控制掺杂剂分布。 还提供了包括多个纳米尺度切换装置的交叉开关阵列，以及用于制造至少一个纳米级切换装置的工艺。

公开(公告)号：US20120113419A1

公开(公告)日：2012-05-10

申请号：US13383387

申请日：2009-07-30

Applicant: Shih-Yuan Wang ,  Jingjing Li ,  Huei Pei Kuo ,  David A. Fattal ,  Nobuhiko Kobayashi ,  Zhiyong Li

Inventor： Shih-Yuan Wang ,  Jingjing Li ,  Huei Pei Kuo ,  David A. Fattal ,  Nobuhiko Kobayashi ,  Zhiyong Li

IPC: G01J3/44 ,  B82Y99/00

CPC classification number: G01N21/658 ,  B82Y15/00 ,  G01J3/44

Abstract: Embodiments of the present invention are directed to nanowire-based systems for performing surface-enhanced Raman spectroscopy. In one embodiment, a system comprises a substrate (102) having a surface and a plurality of tapered nanowires (104) disposed on the surface. Each nanowire has a tapered end directed away from the surface. The system also includes a plurality of nanoparticles (110) disposed near the tapered end of each nanowire. When each nanowire is illuminated with light of a pump wavelength, Raman excitation light is emitted from the tapered end of the nanowire to interact with the nanoparticles and produce enhanced Raman scattered light from molecules located in close proximity to the nanoparticles.

Abstract translation: 本发明的实施方案涉及用于进行表面增强拉曼光谱的基于纳米线的系统。 在一个实施例中，系统包括具有表面的基板（102）和设置在表面上的多个锥形纳米线（104）。 每个纳米线具有远离表面的锥形端。 该系统还包括在每个纳米线的锥形端附近设置的多个纳米颗粒（110）。 当每个纳米线被泵浦波长的光照射时，拉曼激发光从纳米线的锥形端发射以与纳米颗粒相互作用，并从位于紧邻纳米颗粒的分子产生增强的拉曼散射光。

公开(公告)号：US20120105841A1

公开(公告)日：2012-05-03

申请号：US12915148

申请日：2010-10-29

Applicant: Min Hu ,  Michael Josef Stuke ,  Zhiyong Li ,  Wei Wu ,  Fung Suong Ou ,  Shih-Yuan Wang ,  Lars Helge Thylen

Inventor： Min Hu ,  Michael Josef Stuke ,  Zhiyong Li ,  Wei Wu ,  Fung Suong Ou ,  Shih-Yuan Wang ,  Lars Helge Thylen

IPC: G01J3/44

CPC classification number: G01J3/44 ,  G01N21/658

Abstract: An apparatus for performing surface enhanced Raman spectroscopy (SERS) includes a substrate and a plurality of nano-pillars, each of the plurality of nano-pillars having a first end attached to the substrate, a second end located distally from the substrate, and a body portion extending between the first end and the second end, in which the plurality of nano-pillars are arranged in an array on the substrate, and in which each of the plurality of nano-pillars is formed of a polymer material that is functionalized to expand in the presence of a fluid to cause gaps between the plurality of nano-pillars to shrink when the fluid is supplied onto the nano-pillars.

Abstract translation: 用于进行表面增强拉曼光谱（SERS）的设备包括基底和多个纳米柱，多个纳米柱中的每一个具有连接到基底的第一端，位于远离基底的第二端，以及 主体部分在所述第一端和所述第二端之间延伸，其中所述多个纳米柱以阵列布置在所述基底上，并且所述多个纳米柱中的每一个由聚合物材料形成，所述聚合物材料被官能化为 在存在流体的情况下膨胀，以便当将流体供应到纳米支柱上时，使多个纳米柱之间的间隙收缩。

公开(公告)号：US20120105840A1

公开(公告)日：2012-05-03

申请号：US12914655

申请日：2010-10-28

Applicant: Michael Josef Stuke ,  Shih-Yuan Wang ,  Zhiyong Li

Inventor： Michael Josef Stuke ,  Shih-Yuan Wang ,  Zhiyong Li

IPC: G01J3/44 ,  B82Y15/00

CPC classification number: B82Y15/00 ,  G01N21/65 ,  G01N21/658

Abstract: A sensing device that produces a Raman signal includes micro-rods or nano-rods arranged on a substrate in a two-dimensional (2D) array, each of the rods having a length in a single row being substantially the same, with the rod length of each row being different from the rod length of each other row. Each row of rods has a respective resonant vibration frequency that varies from row to row. A source of vibration energy, operatively connected to the substrate, excites vibration in each of the rods such that a responding row resonates when an exciting frequency approaches the resonant vibration frequency of the responding row. A method includes exposing the 2D array to a light source and analyzing Raman scattering at each rod of the 2D array to render a Raman map.

Abstract translation: 产生拉曼信号的感测装置包括以二维（2D）阵列布置在基底上的微棒或纳米棒，每根棒具有基本上相同的长度，其中棒长度 每行的距离与每隔一行的杆长度不同。 每排棒具有相应的谐振振动频率，其逐行变化。 可操作地连接到基板的振动能量源激发每个杆中的振动，使得当激励频率接近响应行的谐振振动频率时，响应行谐振。 一种方法包括将2D阵列暴露于光源并分析2D阵列的每个杆处的拉曼散射以呈现拉曼图。

公开(公告)号：US20120092660A1

公开(公告)日：2012-04-19

申请号：US12905891

申请日：2010-10-15

Applicant: Wei Wu ,  Zhiyong Li ,  Shih-Yuan Wang ,  Michael Josef Stuke ,  Lars Helge Thylen ,  Fung Suong Ou ,  Min Hu

Inventor： Wei Wu ,  Zhiyong Li ,  Shih-Yuan Wang ,  Michael Josef Stuke ,  Lars Helge Thylen ,  Fung Suong Ou ,  Min Hu

IPC: G01J3/44

CPC classification number: G01N21/658

Abstract: An apparatus for performing SERS includes a substrate and flexible nano-fingers, each of the nano-fingers having a first end attached to the substrate, a free second end, and a body portion extending between the first end and the second end, in which the nano-fingers are arranged in an array on the substrate. The apparatus also includes an active material layer disposed on each of the second ends of the plurality of nano-fingers, in which the nano-fingers are to be in a substantially collapsed state in which the active layers on at least two of the nano-fingers contact each other under dominant attractive forces between the plurality of nano-fingers and in which the active material layers are to repel each other when the active material layers are electrostatically charged.

Abstract translation: 用于执行SERS的装置包括基底和柔性纳米指，每个纳米指具有连接到基底的第一端，自由的第二端和在第一端和第二端之间延伸的主体部分，其中 纳米手指以阵列排列在基板上。 该装置还包括设置在多个纳米手指的每个第二端上的活性材料层，其中纳米指状物将处于基本上塌陷的状态，其中在至少两个纳米手指上的活性层， 手指在多个纳米手指之间的主导吸引力下彼此接触，并且当活性材料层被静电充电时，活性材料层将彼此排斥。

公开(公告)号：US20110317160A1

公开(公告)日：2011-12-29

申请号：US13254897

申请日：2009-03-13

Applicant: Zhiyong Li ,  Min Hu

Inventor： Zhiyong Li ,  Min Hu

IPC: G01J3/44 ,  B29C35/02 ,  C23F1/02 ,  B29C70/00

CPC classification number: G01N21/554 ,  B82Y30/00 ,  G01N21/553 ,  G01N21/658

Abstract: Broad band structures for surface enhanced Raman spectroscopy are disclosed herein. Each embodiment of the structure is made up of a metal layer, and a dielectric layer established on at least a portion of the metal layer. The dielectric layer has a controlled thickness that varies from at least one portion of the dielectric layer to at least another portion of the dielectric layer. Nanostructures are established on the dielectric layer at least at the portion and the other portion, the nanostructures thus being configured to exhibit variable plasmon resonances.

Abstract translation: 本文公开了用于表面增强拉曼光谱的宽带结构。 结构的每个实施例由金属层和建立在金属层的至少一部分上的电介质层组成。 电介质层具有从电介质层的至少一部分到电介质层的至少另一部分变化的受控厚度。 至少在部分和另一部分，在电介质层上建立纳米结构，因此纳米结构被构造成表现出可变的等离子体共振。

公开(公告)号：US20110267609A1

公开(公告)日：2011-11-03

申请号：US12771824

申请日：2010-04-30

Applicant: Wei WU ,  Min Hu ,  Fung Suong Ou ,  Zhiyong Li

Inventor： Wei WU ,  Min Hu ,  Fung Suong Ou ,  Zhiyong Li

IPC: G01J3/44

CPC classification number: G01N21/658 ,  B82Y15/00

Abstract: An apparatus for performing Surface Enhanced Raman Spectroscopy (SERS) includes a reflective layer positioned above the substrate, a plurality of tapered nanowires disposed above the reflective layer, each of the plurality of tapered nanowires having a tapered end directed away from the reflective layer.

Abstract translation: 用于进行表面增强拉曼光谱（SERS）的设备包括位于衬底上方的反射层，设置在反射层上方的多个锥形纳米线，多个锥形纳米线中的每一个具有远离反射层的锥形端。

公开(公告)号：US08048377B1

公开(公告)日：2011-11-01

申请号：US10795730

申请日：2004-03-08

Applicant: Zhang-Lin Zhou ,  Zhiyong Li ,  Sean Xiao-An Zhang

Inventor： Zhang-Lin Zhou ,  Zhiyong Li ,  Sean Xiao-An Zhang

IPC: G01N27/00 ,  C12M1/00 ,  G01N21/75

CPC classification number: G01N33/54373 ,  B82Y15/00 ,  B82Y30/00 ,  Y10S977/70 ,  Y10S977/742 ,  Y10S977/745 ,  Y10S977/842

Abstract: The present invention is drawn toward a chemical or biological sensor that can comprise a semi-conducting nanowire and a chemical or biological sensing molecule tethered to the semi-conducting nanowire through a spacer group including a hydrophilic reactive group. In one embodiment, the semi-conducting nanowire can be part of an array of like or similar semi-conducting nanowires. Electrical leads can provide an electrical current to the array, and a signal measurement apparatus can be electrically coupled to the array, and can be configured for detecting changes in the electrical current of the array.

Abstract translation: 本发明涉及化学或生物传感器，其可以包括通过包括亲水反应性基团的间隔基团连接到半导体纳米线的半导体纳米线和化学或生物传感分子。 在一个实施例中，半导体纳米线可以是类似或类似的半导体纳米线阵列的一部分。 电引线可以向阵列提供电流，并且信号测量装置可以电耦合到阵列，并且可以被配置为检测阵列的电流的变化。

公开(公告)号：US20110253966A1

公开(公告)日：2011-10-20

申请号：US12763091

申请日：2010-04-19

Applicant: Janice H. Nickel ,  Michael Renne Ty Tan ,  Zhiyong Li

Inventor： Janice H. Nickel ,  Michael Renne Ty Tan ,  Zhiyong Li

IPC: H01L45/00 ,  H01L21/02 ,  H01L27/24

CPC classification number: H01L45/085 ,  H01L27/2463 ,  H01L45/1233 ,  H01L45/146

Abstract: A nanoscale switching device is provided, comprising: a first electrode of a nanoscale width; a second electrode of a nanoscale width; an active region disposed between the first and second electrodes, the active region having at least one non-conducting layer comprising an electronically semiconducting or nominally insulating and a weak ionic conductor switching material capable of carrying a species of dopants and transporting the dopants under an electric field; and a source layer interposed between the first electrode and the second electrode and comprising a highly reactive and highly mobile ionic species that reacts with a component in the switching material to create dopants that are capable of drifting through the non-conducting layer under an electric field, thereby controlling dopant profile by ionic modulation. A crossbar array comprising a plurality of the nanoscale switching devices is also provided, along with a process for making at least one nanoscale switching device.

Abstract translation: 提供一种纳米级切换装置，包括：纳米级宽度的第一电极; 纳米级宽度的第二电极; 有源区域，设置在第一和第二电极之间，有源区域具有至少一个非导电层，包括电子半导体或名义上绝缘的和弱离子导体开关材料，能够携带一种掺杂剂并在电气下传输掺杂剂 领域; 以及插入在所述第一电极和所述第二电极之间的源极层，并且包括高反应性和高度移动的离子物质，其与所述开关材料中的组分反应以产生能够在电场下漂移通过所述非导电层的掺杂剂 ，从而通过离子调制控制掺杂剂分布。 还提供了包括多个纳米尺度切换装置的交叉开关阵列，以及用于制造至少一个纳米级切换装置的工艺。