公开(公告)号：USD749214S1

公开(公告)日：2016-02-09

申请号：US29508605

申请日：2014-11-07

Applicant: NIPRO CORPORATION

Designer： Masayuki Uenishi ,  Hiroyuki Nakagami ,  Tomohiro Uchimura ,  Shingo Sakamoto

公开(公告)号：US20150306260A1

公开(公告)日：2015-10-29

申请号：US14650247

申请日：2013-12-05

Applicant: NIPRO CORPORATION

Inventor： Yoshihiko Sano ,  Toshiaki Masuda ,  Takeshi Yamaguchi

IPC: A61L2/08

CPC classification number: A61L2/081 ,  A61L2/0035 ,  A61L2202/181 ,  A61L2202/22

Abstract: A medical device made of an ester resin, such as a hollow-fiber-type blood treatment device, is put into a packaging material made of a gas-impermeable material, and, with at least a reducing gas, such as hydrogen gas, being further enclosed therein, the packaging material is hermetically sealed to provide a medical device package. The medical device package is exposed to radiation to sterilize the inside thereof. In the medical device package, an oxygen scavenger may be further enclosed. The reducing gas may be mixed with an inert gas and enclosed as a mixed gas. As a result, it becomes possible to effectively suppress the generation of by-products, such as acetic acid, from the ester resin.

Abstract translation: 将由诸如中空纤维型血液处理装置的酯树脂制成的医疗装置放入由不透气材料制成的包装材料中，并且至少使用诸如氢气的还原气体 进一步包封在其中，包装材料被密封以提供医疗装置包装。 医疗器械包被暴露于辐射以对其内部进行灭菌。 在医疗器械包装中，可以进一步封闭除氧剂。 还原气体可以与惰性气体混合并作为混合气体封闭。 结果，能够有效地抑制来自酯树脂的乙酸等副产物的产生。

公开(公告)号：US20150272889A1

公开(公告)日：2015-10-01

申请号：US14679447

申请日：2015-04-06

Applicant: Nipro Corporation

Inventor： Yohei Hoashi ,  Hirofumi Takeuchi

IPC: A61K9/20 ,  A61K9/00

CPC classification number: A61K9/2018 ,  A61K9/0053 ,  A61K9/0056 ,  A61K9/2009 ,  A61K9/2095 ,  A61K47/02 ,  A61K47/26

Abstract: It is an object to provide an orally disintegrating tablet produced by dry granulation and compression, having a hardness of 40 N or more, a disintegration time of 30 seconds or shorter, a friability of 0.1% or less, and an excellent feeling upon ingestion, that is capable of disintegrating with a small amount of water, having a rapid disintegration time, and being maintained stably in a tablet form, which could not been achieved by conventional procedures. Disclosed is an orally disintegrating tablet produced by dry granulation which contains a medicinal ingredient with silica, and sugar alcohol or/and sugar.

Abstract translation: 本发明的目的是提供通过干法制粒和压缩制备的口腔崩解片，其硬度为40N以上，崩解时间为30秒以下，脆性为0.1％以下，摄取时的感觉优异， 能够以少量的水分解，具有快速的崩解时间，并且以通过常规方法不能实现的片剂形式稳定地保持。 公开了一种通过干法制粒生产的口腔崩解片剂，其含有药用成分与二氧化硅，糖醇或糖和糖。

公开(公告)号：US20150234047A1

公开(公告)日：2015-08-20

申请号：US14408392

申请日：2013-06-14

Applicant: NIPRO CORPORATION

Inventor： Ryoichi Fukasawa ,  Shigenori Tominaga

IPC: G01S17/02

CPC classification number: G01S17/026 ,  G01N21/3581 ,  G01N21/3586 ,  G01N21/85

Abstract: A foreign matter detecting apparatus includes an oscillating unit, an optical system, a receiving unit, a scanning mechanism, and an operator. The oscillating unit generates a terahertz pulse wave and emits the terahertz pulse wave as irradiation light. The optical system guides the irradiation light to the first part of the container and condenses reflected light from the container. The receiving unit outputs a signal corresponding to the condensed reflected light and also measures an echo. The scanning mechanism scans a position of the irradiation light guided on the first part in a two-dimensional manner. The operator detects foreign matter in powder in a container based on at least one of a time waveform signal, a reflection image, a power spectrum, a tomographic image, and a frequency image. The time waveform signal is output from the receiving unit in chronological order.

Abstract translation: 异物检测装置包括振荡单元，光学系统，接收单元，扫描机构和操作者。 振荡单元产生太赫兹脉冲波并发射太赫兹脉冲波作为照射光。 光学系统将照射光引导到容器的第一部分并且冷凝来自容器的反射光。 接收单元输出与聚光反射光相对应的信号，并测量回波。 扫描机构以二维方式扫描在第一部分上引导的照射光的位置。 基于时间波形信号，反射图像，功率谱，断层图像和频率图像中的至少一个，操作者在容器中检测粉末中的异物。 时间波形信号从接收单元按时间顺序输出。

公开(公告)号：US20150231312A1

公开(公告)日：2015-08-20

申请号：US14429565

申请日：2013-09-13

Applicant: Osaka University ,  Nipro Corporation ,  Ono Pharmaceutical Co., Ltd.

Inventor： Yoshiki Sawa ,  Shigeru Miyagawa ,  Satsuki Fukushima ,  Atsuhiro Saito ,  Yoshiki Sakai ,  Kazuhisa Matsuda ,  Takayuki Maruyama

IPC: A61L31/16 ,  A61L31/14 ,  A61K9/00 ,  A61K9/16 ,  A61K31/4406 ,  A61K31/343

CPC classification number: A61L31/16 ,  A61F2/2481 ,  A61K9/0024 ,  A61K9/16 ,  A61K9/1647 ,  A61K31/343 ,  A61K31/4406 ,  A61K47/42 ,  A61L17/005 ,  A61L17/12 ,  A61L17/145 ,  A61L31/06 ,  A61L31/10 ,  A61L31/146 ,  A61L31/148 ,  A61L2300/412 ,  A61L2300/622 ,  A61L2430/20 ,  C08L89/00 ,  C08L89/06 ,  C08L67/04

Abstract: Provided is an advanced heart failure treatment material, as a myocardial/cardiovascular regeneration device, that self-assembles, which can improve the universality and be used in an emergency by commercialization with no need of cell-culturing (cell-free) by controlling stem cells, and has a high therapeutic effect on the fundamental treatment of intractable cardiovascular diseases, in particular, advanced heart failure, in which not only the saving of lives but also improving the patient's quality of life (QOL) are urgent issues. The advanced heart failure treatment material includes a pharmaceutical agent, an agent holding for the pharmaceutical agent, and a myocardial support device.

Abstract translation: 提供了一种先进的心力衰竭治疗材料，作为心肌/心血管再生装置，可自我组装，可以通过商业化提高普遍性并在紧急情况下使用，无需细胞培养（无细胞），通过控制茎 对于顽固性心血管疾病，特别是晚期心力衰竭的基础治疗具有很高的治疗效果，其中不仅挽救生命，而且改善患者的生活质量（QOL）是迫切的问题。 先进的心力衰竭治疗材料包括药剂，用于药剂的药剂和心肌支持装置。

公开(公告)号：US09101749B2

公开(公告)日：2015-08-11

申请号：US14348486

申请日：2012-10-02

Applicant: NIPRO CORPORATION

Inventor： Hiroyuki Nakagami ,  Tatsuya Kudo ,  Tomohiro Uchimura

IPC: A61M5/178 ,  A61M39/06 ,  A61M25/00

CPC classification number: A61M39/0613 ,  A61M25/0017 ,  A61M25/0097 ,  A61M39/06 ,  A61M2039/062 ,  A61M2039/064

Abstract: An indwelling catheter including: a hollow catheter base having a tip and a back end, the back end being able to receive and connect a male connector; a tube provided at the tip of the catheter base; a flexible hemostasis valve installed inside the catheter base; a pusher installed at a back of the hemostasis valve; and a pusher guide installed between the pusher and the catheter base. The pusher has a hollow constitution whose taper reduces in diameter facing its tip. The pusher guide is able to restrict a position of the pusher at a first position where the pusher does not push open the hemostasis valve and a second position where the taper of the pusher is positioned inside the hemostasis valve and pushes open the hemostasis valve.

Abstract translation: 一种留置导管，包括：具有尖端和后端的中空导管基座，所述后端能够容纳并连接阳连接器; 设置在导管基座的尖端处的管; 安装在导管底座内的柔性止血阀; 安装在止血阀背面的推动器; 以及安装在推动器和导管基座之间的推动器引导件。 推动器具有中空构造，其锥形直径朝向其尖端减小。 推动器引导件能够在推动器不推动止血阀的第一位置和推动器的锥形位于止血阀内部并且推动止血阀的第二位置处限制推动器的位置。

公开(公告)号：USD721171S1

公开(公告)日：2015-01-13

申请号：US29459687

申请日：2013-07-02

Applicant: Nipro Corporation

Designer： Koichi Murai

公开(公告)号：US08926645B2

公开(公告)日：2015-01-06

申请号：US13864859

申请日：2013-04-17

Applicant: Nipro Corporation

Inventor： Kohzo Ishikura ,  Tomohiro Uchimura ,  Ken Suzuki

IPC: A61B17/34 ,  A61B5/151 ,  A61B5/15

CPC classification number: A61B5/15144 ,  A61B5/1411 ,  A61B5/150022 ,  A61B5/150412 ,  A61B5/150519 ,  A61B5/150549 ,  A61B5/150618 ,  A61B5/150717 ,  A61B5/150916 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/1513 ,  A61B5/15142

Abstract: A disposable lancing device including: a lancet housed in a housing and urged by a spring member such that a puncture member provided at a distal end of the lancet is adapted to extend out from the housing so as to carry out a puncturing operation; a locking ring disposed within the housing such that the lancet is allowed to displace in an extension direction through the locking ring; a locking protrusion provided to the lancet and adapted to be engaged by the locking ring so as to hold the lancet in a puncture-ready position located deep in the housing with the spring member being compressed; and an operating member adapted to carry out the puncturing operation by rotating the locking ring so as to disengage the locking protrusion from the locking ring and displace the lancet in the extension direction by means of the spring member.

Abstract translation: 一种一次性穿刺装置，包括：容纳在壳体中并由弹簧构件推动的刺血针，使得设置在所述柳叶刀的前端的穿刺构件适于从所述壳体延伸出来，以进行穿刺操作; 锁定环，其设置在所述壳体内，使得所述柳叶刀能够沿延伸方向移动通过所述锁定环; 锁定突起，其设置在所述柳叶刀上，并且适于与所述锁定环接合，以将所述柳叶刀保持在位于所述壳体内的穿刺准备位置，同时所述弹簧构件被压缩; 以及操作构件，其适于通过旋转所述锁定环来执行所述穿刺操作，以使所述锁定突起与所述锁定环脱离并且借助于所述弹簧构件沿所述延伸方向移位所述柳叶刀。

公开(公告)号：US20140326635A1

公开(公告)日：2014-11-06

申请号：US14363070

申请日：2012-12-07

Applicant: Nipro Corporation

Inventor： Kazuaki Uetake

IPC: A61J1/03

CPC classification number: A61J1/035 ,  A61J7/04 ,  A61J2205/30 ,  B65D75/327 ,  B65D2575/3263 ,  B65D2575/3281

Abstract: A medicine packaging PTP sheet capable of protecting a pocket from pressurization by external force in a combined state in which the medicine packaging PTP sheet has a first sheet in which a pocket capable of accommodating a medicine and a projecting convex portion each are projected from the upper surface and a second sheet which is attached to the lower surface of the first sheet and blocks an opening of the pocket. A first distance L1 from the upper surface of the first sheet to the projection end of the convex portion is longer than a second distance L2 from the upper surface of the first sheet to the projection end of the pocket.

Abstract translation: 一种医药包装PTP片，其能够以组合状态保护口袋免受外力加压，其中药物包装PTP片具有第一片，其中可以容纳药物的口袋和突出的凸起部分从上部突出 表面和第二片，其附接到第一片的下表面并且阻挡口袋的开口。 从第一片的上表面到凸部的突出端的第一距离L1比从第一片的上表面到袋的突出端的第二距离L2长。

公开(公告)号：US20040188281A1

公开(公告)日：2004-09-30

申请号：US10800885

申请日：2004-03-15

Applicant: NIPRO CORPORATION

Inventor： Masanobu Iwasa ,  Minoru Honda ,  Masaki Ikenoue ,  Kenji Omori

IPC: B65D025/08 ,  B65D085/00

CPC classification number: A61J1/1412 ,  A61J1/10 ,  A61J1/1406 ,  A61J1/1462 ,  A61J1/1487 ,  A61J1/18 ,  A61J1/2024 ,  A61J1/2093 ,  A61J2205/30 ,  B32B1/00

Abstract: A medicine bag, which includes a bag body having a medicine storage chamber that stores a medicine in such a way that the medicine is visually confirmed through a light-transmission portion provided in at least one part of the bag body, the bag body having a weak seal portion that divides the medicine storage chamber into a plurality of division spaces, and the sealing of the weak seal portion adjacent to a specific division space being removed by increasing the internal pressure of that division space, including: a cover sheet which is peelably attached to the bag body; and a requisitely-used portion which is used in the process shortly before the medicine is administered, in which the cover sheet includes: a light-shielding portion which shields from the light the medicine stored in at least one division space by covering a predetermined part of the light-transmission portion; and a continuously-formed portion which is continuously formed in the light-shielding portion and is placed so that the requisitely-used portion is prevented from being used with the cover sheet kept attached.

Abstract translation: 一种药袋，其具有袋体，所述袋体具有药剂储存室，所述药剂储存室以通过设置在所述袋体的至少一部分的透光部目视确认所述药物的方式存储药物，所述袋体具有 将药剂储存室分割为多个分隔空间的弱密封部，通过增加该分隔空间的内压来除去与特定分隔空间相邻的弱密封部的密封，包括：可剥离的覆盖片 附在袋体上; 以及在药物被施用之前不久使用的必要使用部分，其中所述覆盖片包括：遮光部，其通过覆盖预定部分遮挡光存储在至少一个分割空间中的药物 的光传输部分; 以及连续地形成在遮光部分中的连续形成部分，并且被放置成防止被保护的部分与被保持附着的盖板一起使用。