公开(公告)号：US07594730B2

公开(公告)日：2009-09-29

申请号：US11547922

申请日：2005-03-11

Applicant: Adrian Podoleanu

Inventor： Adrian Podoleanu

IPC: A61B3/00 ,  A61B3/02 ,  A61B3/10

CPC classification number: G01B9/02091 ,  A61B3/102 ,  G01B9/02083

Abstract: OCT cross section images of a part of a curved object are displayed by creating a series of image points and placing each image point into a corrected image in such a way that the positions of scattering points within the image coincide with or are at least closer to their real spatial distribution within the curved object.

Abstract translation: 通过创建一系列图像点并将每个图像点放置在校正图像中，使得图像内的散射点的位置与图像中的位置一致或至少更接近于图像点来显示弯曲物体的一部分的OCT截面图像 它们在曲线对象内的实际空间分布。

公开(公告)号：US20070046948A1

公开(公告)日：2007-03-01

申请号：US11239677

申请日：2005-09-30

Applicant: Adrian Podoleanu ,  Adrian Bradu ,  Chris Dainty ,  David Merino

Inventor： Adrian Podoleanu ,  Adrian Bradu ,  Chris Dainty ,  David Merino

IPC: G01B11/02

CPC classification number: A61B3/102 ,  A61B3/1025 ,  A61B3/14

Abstract: Optical mapping apparatus for imaging an object, comprising an optical coherence tomography (OCT) system including an OCT source, an OCT reference path leading from the OCT source to an OCT receiver, an OCT object path leading from the object to the OCT coupler, an OCT depth scanner adapted to alter at least one of the OCT reference path and the OCT receiver path. A confocal system is provided including a confocal optical receiver a confocal path leading from the object to the confocal optical receiver via a confocal input aperture. An adaptive optics (AO) system is provided to correct optical aberrations in the OCT object path and the confocal path.

Abstract translation: 用于对物体成像的光学映射设备，包括包括OCT源，从OCT源引导到OCT接收器的OCT参考路径的光学相干断层摄影（OCT）系统，从对象引导到OCT耦合器的OCT对象路径， OCT深度扫描器适于改变OCT参考路径和OCT接收器路径中的至少一个。 提供了共焦系统，其包括共聚焦光学接收器，其经由共焦输入孔从物体引导到共焦光学接收器。 提供自适应光学（AO）系统来校正OCT对象路径和共焦路径中的光学像差。

公开(公告)号：US20060055938A1

公开(公告)日：2006-03-16

申请号：US11216403

申请日：2005-08-31

Applicant: Adrian Podoleanu ,  John Rogers

Inventor： Adrian Podoleanu ,  John Rogers

IPC: G01B11/02

CPC classification number: A61B3/102 ,  G01B9/0201 ,  G01B9/02091 ,  G01B2290/20 ,  G01B2290/35 ,  G01B2290/65 ,  G01N21/4795 ,  G02B17/023 ,  G02B26/06

Abstract: A method for axial scanning to be used in transmission in one of the arms of OCT interferometers, with reduced walk-off and loss. Procedures are disclosed of using the scanning delay line in conjunction with the transverse scanners to generate B and C-scan OCT images.

Abstract translation: 一种用于在OCT干涉仪的一个臂中的透射中的轴向扫描的方法，具有减小的偏离和损失。 公开了使用与横向扫描仪结合的扫描延迟线以产生B和C扫描OCT图像的程序。

公开(公告)号：US08678594B2

公开(公告)日：2014-03-25

申请号：US12958791

申请日：2010-12-02

Applicant: Adrian Podoleanu ,  Michael Leitner

Inventor： Adrian Podoleanu ,  Michael Leitner

IPC: A61B3/10 ,  A61B3/14 ,  A61B3/12 ,  A61B3/103

CPC classification number: A61B3/1225 ,  A61B3/102 ,  A61B3/103 ,  G01B9/02004 ,  G01B9/02027 ,  G01B9/02044 ,  G01B9/02065 ,  G01B9/02089 ,  G01B9/0209

Abstract: A spectral interferometry apparatus and method are disclosed, that can be used to monitor or measure an unknown length by following a characteristic of an indicating signal. The measurement is performed by adjusting an optical path difference (OPD) in an interferometer part of an interferometer configuration until sound or light or both are obtained with the desired strength and pitch. Embodiments are presented where the unknown length is the eye length. Spectral interrogation of the interferometer optical output is achieved by reading the signal of an analogue photodetector array in a spectrometer or by tuning a swept source and processing the signal of a photodetector. Sound of different pitches are produced either directly in this process, or by using a nonlinear amplifier, or a mixer. For enhanced signal, the array may be driven by a nonlinear clock or the swept source may be driven by a distorted driving signal.

Abstract translation: 公开了一种光谱干涉测量装置和方法，其可以用于通过遵循指示信号的特性来监视或测量未知长度。 通过调整干涉仪配置的干涉仪部分中的光程差（OPD）来进行测量，直到以期望的强度和间距获得声音或光或者两者。 呈现其中未知长度是眼睛长度的实施例。 通过读取光谱仪中的模拟光电检测器阵列的信号或通过调谐扫频源并处理光电检测器的信号来实现干涉仪光输出的光谱询问。 在该过程中直接产生不同音调的声音，或者通过使用非线性放大器或混音器产生声音。 对于增强的信号，阵列可以由非线性时钟驱动，或者扫描的源可以由失真的驱动信号驱动。

公开(公告)号：US20110043661A1

公开(公告)日：2011-02-24

申请号：US12866304

申请日：2009-02-06

Applicant: Adrian Podoleanu

Inventor： Adrian Podoleanu

IPC: H04N5/262 ,  H04N5/225

CPC classification number: H04N5/232 ,  A61B3/102 ,  A61B3/14 ,  G01B9/02007 ,  G01B9/0203 ,  G01B9/02049 ,  G01B9/02069 ,  G01B9/02079 ,  G01B9/02091 ,  G01B2290/35 ,  G01B2290/70 ,  G02B21/0056 ,  G02B21/0064 ,  H04N5/2252 ,  H04N5/33

Abstract: The invention describes several embodiments of an adapter which can make use of the devices in any commercially available digital cameras to accomplish different functions, such as a fundus camera, as a microscope or as an en-face optical coherence tomography (OCT) to produce constant depth OCT images or as a Fourier domain (channelled spectrum) optical coherence tomography to produce a reflectivity profile in the depth of an object or cross section OCT images, or depth resolved volumes. The invention admits addition of confocal detection and provides simultaneous measurements or imaging in at least two channels, confocal and OCT, where the confocal channel provides an en-face image simultaneous with the acquisition of OCT cross sections, to guide the acquisition as well as to be used subsequently in the visualisation of OCT images. Different technical solutions are provided for the assembly of one or two digital cameras which together with such adapters lead to modular and portable high resolution imaging systems which can accomplish various functions with a minimum of extra components while adapting the elements in the digital camera. The cost of such adapters is comparable with that of commercial digital cameras, i.e. the total cost of such assemblies of commercially digital cameras and dedicated adapters to accomplish high resolution imaging are at a fraction of the cost of dedicated stand alone instruments. Embodiments and methods are presented to employ colour cameras and their associated optical sources to deliver simultaneous signals using their colour sensor parts to provide spectroscopic information, phase shifting inferometry in one step, depth range extension, polarisation, angular measurements and spectroscopic Fourier domain (channelled spectrum) optical coherence tomography in as many spectral bands simultaneously as the number of colour parts of the photodetector sensor in the digital camera. In conjunction with simultaneous acquistion of a confocal image, at least 4 channels can simultaneously be provided using the three color parts of conventional color cameras to deliver three OCT images in addition to the confocal image.

公开(公告)号：US20080074617A1

公开(公告)日：2008-03-27

申请号：US11547922

申请日：2005-03-11

Applicant: Adrian Podoleanu

Inventor： Adrian Podoleanu

IPC: A61B3/10

CPC classification number: G01B9/02091 ,  A61B3/102 ,  G01B9/02083

Abstract: OCT cross section images of a part of a curved object are displayed by creating a series of image points and placing each image point into a corrected image in such a way that the positions of scattering points within the image coincide with or are at least closer to their real spatial distribution within the curved object.

Abstract translation: 通过创建一系列图像点并将每个图像点放置在校正图像中，使得图像内的散射点的位置与图像中的位置一致或至少更接近于图像点来显示弯曲物体的一部分的OCT截面图像 它们在曲线对象内的实际空间分布。

公开(公告)号：US08619184B2

公开(公告)日：2013-12-31

申请号：US12866304

申请日：2009-02-06

Applicant: Adrian Podoleanu

Inventor： Adrian Podoleanu

IPC: H04N5/225

CPC classification number: H04N5/232 ,  A61B3/102 ,  A61B3/14 ,  G01B9/02007 ,  G01B9/0203 ,  G01B9/02049 ,  G01B9/02069 ,  G01B9/02079 ,  G01B9/02091 ,  G01B2290/35 ,  G01B2290/70 ,  G02B21/0056 ,  G02B21/0064 ,  H04N5/2252 ,  H04N5/33

Abstract: An adapter which can make use of the devices in any commercially available digital cameras to accomplish different functions, the invention admits addition of confocal detection and provides simultaneous measurements or imaging in at least two channels, confocal and OCT, where the confocal channel provides an en-face image simultaneous with the acquisition of OCT cross sections, to guide the acquisition as well as to be used subsequently in the visualization of OCT images. Different technical solutions are provided for the assembly of one or two digital cameras which together with such adapters lead to modular and portable high resolution imaging systems which can accomplish various functions with a minimum of extra components while adapting the elements in the digital camera.

Abstract translation: 可以使用任何市售数码相机中的装置来实现不同功能的适配器，本发明允许加入共聚焦检测，并且在至少两个通道，共聚焦和OCT中提供同时测量或成像，其中共聚焦通道提供en 同时采集OCT横截面，以指导采集以及随后在OCT图像的可视化中使用。 提供了不同的技术解决方案，用于组装一个或两个数字照相机，这些数字照相机与这些适配器一起导致模块化和便携式的高分辨率成像系统，其可以在使数字照相机中的元件适应的同时以最小额外的成分完成各种功能。

公开(公告)号：US08472027B2

公开(公告)日：2013-06-25

申请号：US13178695

申请日：2011-07-08

Applicant: Adrian Podoleanu

Inventor： Adrian Podoleanu

IPC: G01B9/02

CPC classification number: A61B3/102 ,  A61B5/0064 ,  A61B5/0066 ,  A61B5/0073 ,  A61B5/441 ,  A61B5/7203 ,  A61B5/7257 ,  G01B9/02044 ,  G01B9/02069 ,  G01B9/02091 ,  G01N21/4795

Abstract: A spectral interferometry apparatus and method is provided to supply unambiguous profiles (A-scans free of mirror terms) of the reflectivity versus optical path difference and make difference between the positive and negative optical path difference or provide output in a selected interval of optical path differences. The apparatus comprises object optics that transfer a beam from an optical source to a target object (55) to produce an object beam and reference optics that produce a reference beam. Displacing means (57) are provided to produce a gap (g) between the object beam (41′) and the reference beam (42′). Optical spectrum dispersing means (7) such as a grating or a prism receive the two relatively displaced beams, and disperse their spectral content onto a reading element such as a CCD. The combination of the displacing means and the optical spectrum dispersing means creates an intrinsic optical delay between the wavetrains of the object beam and the reference beam which can be used with the optical path difference in the interferometer to generate a channelled spectrum for the optical path difference in the interferometer on the reading element.

Abstract translation: 提供了一种光谱干涉测量装置和方法来提供反射率相对于光程差的明确分布（无镜像的A扫描），并使得在正和负光程差之间产生差异，或者在所选择的光程差间隔中提供输出 。 该装置包括将光束从光源传输到目标物体（55）以产生物体光束和产生参考光束的参考光学器件的物体光学器件。 设置位移装置（57）以在物体光束（41'）和参考光束（42'）之间产生间隙（g）。 诸如光栅或棱镜的光谱分散装置（7）接收两个相对移动的光束，并将其光谱含量分散到诸如CCD的读取元件上。 位移装置和光谱分散装置的组合在物体光束的波长与参考光束之间产生固有的光学延迟，该参考光束可与干涉仪中的光程差用于产生用于光程差的通道光谱 在干涉仪上读取元件。

公开(公告)号：US20120062898A1

公开(公告)日：2012-03-15

申请号：US13178695

申请日：2011-07-08

Applicant: Adrian PODOLEANU

Inventor： Adrian PODOLEANU

IPC: G01B9/02

CPC classification number: A61B3/102 ,  A61B5/0064 ,  A61B5/0066 ,  A61B5/0073 ,  A61B5/441 ,  A61B5/7203 ,  A61B5/7257 ,  G01B9/02044 ,  G01B9/02069 ,  G01B9/02091 ,  G01N21/4795

Abstract: A spectral interferometry apparatus and method is provided to supply unambiguous profiles (A-scans free of mirror terms) of the reflectivity versus optical path difference and make difference between the positive and negative optical path difference or provide output in a selected interval of optical path differences. The apparatus comprises object optics that transfer a beam from an optical source to a target object (55) to produce an object beam and reference optics that produce a reference beam. Displacing means (57) are provided to produce a gap (g) between the object beam (41′) and the reference beam (42′). Optical spectrum dispersing means (7) such as a grating or a prism receive the two relatively displaced beams, and disperse their spectral content onto a reading element such as a CCD. The combination of the displacing means and the optical spectrum dispersing means creates an intrinsic optical delay between the wavetrains of the object beam and the reference beam which can be used with the optical path difference in the interferometer to generate a channelled spectrum for the optical path difference in the interferometer on the reading element.

Abstract translation: 提供了一种光谱干涉测量装置和方法来提供反射率相对于光程差的明确分布（无镜像的A扫描），并使得在正和负光程差之间产生差异，或者在所选择的光程差间隔中提供输出 。 该装置包括将光束从光源传输到目标物体（55）以产生物体光束和产生参考光束的参考光学器件的物体光学器件。 设置位移装置（57）以在物体光束（41'）和参考光束（42'）之间产生间隙（g）。 诸如光栅或棱镜的光谱分散装置（7）接收两个相对移动的光束，并将其光谱含量分散到诸如CCD的读取元件上。 位移装置和光谱分散装置的组合在物体光束的波长与参考光束之间产生固有的光学延迟，该参考光束可与干涉仪中的光程差用于产生用于光程差的通道光谱 在干涉仪上读取元件。

公开(公告)号：US20120013909A1

公开(公告)日：2012-01-19

申请号：US12958791

申请日：2010-12-02

Applicant: Adrian Podoleanu ,  Michael Leitner

Inventor： Adrian Podoleanu ,  Michael Leitner

IPC: G01J3/45 ,  A61B3/10

CPC classification number: A61B3/1225 ,  A61B3/102 ,  A61B3/103 ,  G01B9/02004 ,  G01B9/02027 ,  G01B9/02044 ,  G01B9/02065 ,  G01B9/02089 ,  G01B9/0209

Abstract: A spectral interferometry apparatus and method are disclosed, that can be used to monitor or measure an unknown length by following a characteristic of an indicating signal. The measurement is performed by adjusting an optical path difference (OPD) in an interferometer part of an interferometer configuration until sound or light or both are obtained with the desired strength and pitch. Embodiments are presented where the unknown length is the eye length. Spectral interrogation of the interferometer optical output is achieved by reading the signal of an analogue photodetector array in a spectrometer or by tuning a swept source and processing the signal of a photodetector. Sound of different pitches are produced either directly in this process, or by using a nonlinear amplifier, or a mixer. For enhanced signal, the array may be driven by a nonlinear clock or the swept source may be driven by a distorted driving signal.

Abstract translation: 公开了一种光谱干涉测量装置和方法，其可以用于通过遵循指示信号的特性来监视或测量未知长度。 通过调整干涉仪配置的干涉仪部分中的光程差（OPD）来进行测量，直到以期望的强度和间距获得声音或光或者两者。 呈现其中未知长度是眼睛长度的实施例。 通过读取光谱仪中的模拟光电检测器阵列的信号或通过调谐扫频源并处理光电检测器的信号来实现干涉仪光输出的光谱询问。 在该过程中直接产生不同音调的声音，或者通过使用非线性放大器或混音器产生声音。 对于增强的信号，阵列可以由非线性时钟驱动，或者扫描的源可以由失真的驱动信号驱动。