公开(公告)号：US20060262360A1

公开(公告)日：2006-11-23

申请号：US11134798

申请日：2005-05-20

Applicant: John Dalrymple ,  James Chang

Inventor： John Dalrymple ,  James Chang

IPC: H04N1/46

CPC classification number: H04N1/6033

Abstract: Systems and methods for utilizing metadata embedded in a color measurement target to uniquely identify the target through color measurement. A color measurement target is used for color calibration, color characterization, color adjustment and/or color correction of a color output device and includes a collection of color patches imaged by the output device, wherein metadata is embedded directly into the color patches of the color measurement target to uniquely identify the target through color measurement. The metadata-bearing patches in the target are used to communicate information through color measurement, and can contribute to the color characterization.

公开(公告)号：US20060211770A1

公开(公告)日：2006-09-21

申请号：US11083261

申请日：2005-03-16

Applicant: Chin-Ming Chang ,  James Chang ,  Rhett Schiffman ,  R. Jordan ,  Joan-En Chang-Lin

Inventor： Chin-Ming Chang ,  James Chang ,  Rhett Schiffman ,  R. Jordan ,  Joan-En Chang-Lin

IPC: A61K31/557 ,  A61K31/14

CPC classification number: A61K31/5575 ,  A01N33/12 ,  A61K9/0048 ,  A61K31/14 ,  A61K31/165 ,  A61K31/557 ,  A61K47/02 ,  A61K47/12

Abstract: A composition comprising from 0.005% to 0.02% bimatoprost by weight and from 100 ppm to 250 ppm benzalkonium chloride, wherein said composition is an aqueous liquid which is formulated for ophthalmic administration is disclosed herein. A method which is useful in treating glaucoma or ocular hypertension related thereto is also disclosed herein.

公开(公告)号：US20060173060A1

公开(公告)日：2006-08-03

申请号：US11395019

申请日：2006-03-31

Applicant: James Chang ,  Patrick Hughes

Inventor： James Chang ,  Patrick Hughes

IPC: A61K31/4166 ,  A61K9/50 ,  A61K9/16

CPC classification number: A61K31/4166

Abstract: Biocompatible microparticles include an ophthalmically active alpha-2 adrenergic receptor agonist and a biodegradable polymer. The microparticles include oil-in-water emulsified microparticles which can be used to treat an ocular condition, such as glaucoma.

公开(公告)号：US20050244473A1

公开(公告)日：2005-11-03

申请号：US11117879

申请日：2005-04-29

Applicant: Patrick Hughes ,  Lon Spada ,  Hiroshi Sugimoto ,  Wendy Blanda ,  James Chang

Inventor： Patrick Hughes ,  Lon Spada ,  Hiroshi Sugimoto ,  Wendy Blanda ,  James Chang

IPC: A61K9/00 ,  A61K31/13 ,  A61F2/00

CPC classification number: A61K9/0051

Abstract: Biocompatible intraocular implants include an anti-excitotoxic agent and a biodegradable polymer that is effective to facilitate release of the anti-excitotoxic agent into an eye for an extended period of time. The therapeutic agents of the implants may be associated with a biodegradable polymer matrix, such as a matrix that is substantially free of a polyvinyl alcohol. The implants may be placed in an eye to treat or reduce the occurrence of one or more ocular conditions, such as retinal damage, including glaucoma and proliferative vitreoretinopathy.

Abstract translation: 生物相容性眼内植入物包括抗兴奋性毒性剂和可生物降解的聚合物，其有效促进抗兴奋性毒性剂长时间释放到眼睛中。 植入物的治疗剂可以与可生物降解的聚合物基质相关，例如基本上不含聚乙烯醇的基质。 植入物可以放置在眼睛中以治疗或减少一种或多种眼部病症的发生，例如视网膜损伤，包括青光眼和增生性玻璃体视网膜病变。

公开(公告)号：US20050156700A1

公开(公告)日：2005-07-21

申请号：US11079717

申请日：2005-03-15

Applicant: James Chang

Inventor： James Chang

IPC: H01F17/00 ,  H01L23/522 ,  H01L27/02 ,  H01L27/08 ,  H03B5/12 ,  H03B5/36 ,  H03D7/16 ,  H03D7/18 ,  H03G1/00 ,  H03H11/12 ,  H03J1/00 ,  H03J3/04 ,  H03J3/08 ,  H03J3/18 ,  H03L7/10 ,  H03L7/23 ,  H04B1/26

CPC classification number: H03L7/23 ,  H01F17/0006 ,  H01F17/0013 ,  H01F2017/0053 ,  H01F2021/125 ,  H01L23/5227 ,  H01L27/0248 ,  H01L27/08 ,  H01L2924/0002 ,  H01L2924/3011 ,  H03B5/364 ,  H03D7/161 ,  H03D7/18 ,  H03G1/0029 ,  H03H11/1291 ,  H03J1/0075 ,  H03J3/04 ,  H03J3/08 ,  H03J3/185 ,  H03J2200/10 ,  H03L7/10 ,  H01L2924/00

Abstract: An integrated receiver with channel selection and image rejection substantially implemented on a single CMOS integrated circuit is described. A receiver front end provides programable attenuation and a programable gain low noise amplifier. Frequency conversion circuitry advantageously uses LC filters integrated onto the substrate in conjunction with image reject mixers to provide sufficient image frequency rejection. Filter tuning and inductor Q compensation over temperature are performed on chip. The filters utilize multi track spiral inductors with shields to increase circuit Q. The filters are tuned using local oscillators to tune a substitute filter, and frequency scaling during filter component values to those of the filter being tuned. In conjunction with filtering, frequency planning provides additional image rejection. The advantageous choice of local oscillator signal generation methods on chip is by PLL out of band local oscillation and by direct synthesis for in band local oscillator. The VCOs in the PLLs are centered using a control circuit to center the tuning capacitance range. A differential crystal oscillator is advantageously used as a frequency reference. Differential signal transmission is advantageously used throughout the receiver. ESD protection is provided by a pad ring and ESD clamping structure that maintains signal integrity. Also provided are shunts at each pin to discharge ESD build up. The shunts utilize a gate boosting structure to provide sufficient small signal RF performance, and minimal parasitic loading.

Abstract translation: 描述了基本上在单个CMOS集成电路上实现的具有信道选择和图像抑制的集成接收机。 接收机前端提供可编程衰减和可编程增益低噪声放大器。 频率转换电路有利地使用集成到衬底上的LC滤波器与图像抑制混合器结合，以提供足够的图像频率抑制。 过滤器调谐和电感Q补偿温度在芯片上执行。 滤波器利用具有屏蔽的多轨螺旋电感器来增加电路Q.使用本地振荡器调谐滤波器以调整替代滤波器，以及在滤波器组件值期间频率缩放至正被调谐的滤波器的滤波器。 结合滤波，频率规划提供了额外的镜像抑制。 片上本地振荡器信号产生方法的有利选择是通过PLL带外本地振荡和通过频带本地振荡器的直接合成。 PLL中的VCO使用控制电路居中，使调谐电容范围居中。 差分晶体振荡器有利地用作频率参考。 差分信号传输有利地用于整个接收机。 ESD保护由保护信号完整性的焊盘环和ESD钳位结构提供。 还提供每个引脚上的分流器，以放电ESD积聚。 分流器利用栅极升压结构来提供足够的小信号RF性能和最小的寄生负载。

公开(公告)号：US20050031697A1

公开(公告)日：2005-02-10

申请号：US10911966

申请日：2004-08-05

Applicant: Joseph Vehige ,  James Chang ,  Richard Graham ,  Robert Lyons ,  Teresa Kuan ,  Chin-Ming Chang

Inventor： Joseph Vehige ,  James Chang ,  Richard Graham ,  Robert Lyons ,  Teresa Kuan ,  Chin-Ming Chang

IPC: A61K9/00 ,  A61K31/00 ,  A61K9/14

CPC classification number: A61K31/407 ,  A61K9/0048 ,  A61K31/00 ,  A61K47/38

Abstract: The present invention provides for compositions for administering a therapeutically effective amount of a therapeutic component. The compositions may include an ophthalmically acceptable carrier component; a therapeutically effective amount of a therapeutic component; and a retention component which may be effective to reduce wettability, induce viscosity, increase muco-adhesion, increase meniscus height on a cornea of an eye and/or increase physical apposition to a cornea of an eye of a composition.

Abstract translation: 本发明提供了用于施用治疗有效量的治疗成分的组合物。 组合物可以包括眼科可接受的载体组分; 治疗有效量的治疗成分; 以及可以有效地降低润湿性，诱导粘度，增加粘膜粘附，增加眼睛角膜上的弯液面高度和/或增加与组合物的眼睛的角膜的物理连接的保留组分。

公开(公告)号：US06636374B1

公开(公告)日：2003-10-21

申请号：US09556887

申请日：2000-04-19

Applicant: Ban Hok Goh ,  Nan Ling Goh ,  Tze Ming Jimmy Pang ,  Kah Liang Gan ,  LaiKein James Chang

Inventor： Ban Hok Goh ,  Nan Ling Goh ,  Tze Ming Jimmy Pang ,  Kah Liang Gan ,  LaiKein James Chang

IPC: G11B2102

CPC classification number: G11B5/54 ,  G11B19/20 ,  G11B21/12

Abstract: A system for hardware intelligent speed monitoring and auto-retract is disclosed. The system contains a monitoring device that monitors the TACH (Tachometer) output of motor driver. The device provides a trigger to the signal processor and a retract mechanism to retract the actuator when the spindle motor speed is unexpectedly much higher or lower than normal speed. The system DSP (Digital Signal Processor) is unaware of such occurrence.

Abstract translation: 公开了一种用于硬件智能速度监测和自动缩回的系统。 该系统包含监控电机驱动器的TACH（转速表）输出的监控装置。 当主轴电机速度意外地高于或低于正常速度时，该装置向信号处理器提供触发器和一个缩回机构以使致动器缩回。 系统DSP（数字信号处理器）不知道这种情况。

公开(公告)号：US6016437A

公开(公告)日：2000-01-18

申请号：US138455

申请日：1998-08-21

Applicant: Hosheng Tu ,  Chi-Wu James Chang

Inventor： Hosheng Tu ,  Chi-Wu James Chang

IPC: A61B5/042 ,  A61B18/14 ,  A61B5/04

CPC classification number: A61B5/0422 ,  A61B18/1492 ,  A61B5/6853 ,  A61B5/6858 ,  A61B2017/003 ,  A61B2018/00148 ,  A61B2018/00154 ,  A61B2018/0016 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2018/00839 ,  A61B2018/00898 ,  A61B2018/1467 ,  A61B2562/0209 ,  A61B2562/043

Abstract: A cardiovascular catheter probe system suitable for electrophysiology mapping and radiofrequency ablation of cardiac tissue comprises a plurality of catheter shafts having a proximal end, a distal handle, and a lumen extending therebetween, wherein a distal portion of the shaft is deflectable and inflatable; the wavy soft distal section is inflatable to conform intimately to the irregular intracardiac tissue surface, wherein conducting electrodes are secured on the hills of said inflatable wavy soft shaft.

Abstract translation: 适用于心脏组织的电生理学测绘和射频消融的心血管导管探针系统包括多个导管轴，其具有近端，远端手柄和在其间延伸的内腔，其中所述轴的远端部分是可偏转和可充气的; 波状柔软的远端部分可充气以与不规则的心脏内组织表面紧​​密配合，其中导电电极固定在所述可充气的波浪软轴的山丘上。

公开(公告)号：US5013908A

公开(公告)日：1991-05-07

申请号：US276629

申请日：1988-11-28

Applicant: James Chang

Inventor： James Chang

IPC: G01M11/08 ,  G08B13/12

CPC classification number: G01M11/083 ,  G08B13/124 ,  G08B13/186

Abstract: A fiber optic detection system comprising an array of fiber optic elements is presented. Each fiber optic element is uniquely encoded using a plurality of discrete ferquencies, digital codes or other encoding techniques. When a break occurs in one or more fiber optic elements, the missing light frequencies or digital codes are sensed, thereby indicating the break. Preferably, the fiber optic elements are arranged in a grid pattern so that precise location of the break can be made.

Abstract translation: 提出了一种包括光纤元件阵列的光纤检测系统。 每个光纤元件使用多个离散傅里叶变换，数字代码或其他编码技术进行唯一编码。 当在一个或多个光纤元件中发生中断时，感测到丢失的光频率或数字码，从而指示断开。 优选地，光纤元件以网格图案布置，使得可以进行断裂的精确位置。

公开(公告)号：US08722097B2

公开(公告)日：2014-05-13

申请号：US11371118

申请日：2006-03-08

Applicant: James Chang ,  Patrick Hughes ,  Chin-Ming Chang

Inventor： James Chang ,  Patrick Hughes ,  Chin-Ming Chang

IPC: A61K9/50 ,  B01J13/02 ,  B01J13/04

CPC classification number: A61K31/5575 ,  A61K9/0048 ,  A61K9/0051 ,  A61K9/107 ,  A61K9/1075 ,  A61K9/146 ,  A61K9/1647 ,  A61K9/1694 ,  A61K31/165 ,  A61K47/34 ,  B01J13/04 ,  B01J13/06

Abstract: Biocompatible microparticles include an ophthalmically active cyclic lipid component and a biodegradable polymer that is effective, when placed into the subconjunctival space, in facilitating release of the cyclic lipid component into the anterior and posterior segments of an eye for an extended period of time. The cyclic lipid component can be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. Or, the cyclic lipid component can be encapsulated by the polymeric component. The present microparticles include oil-in-water emulsified microparticles. The subconjunctivally administered microparticles can be used to treat or to reduce at least one symptom of an ocular condition, such as glaucoma or age related macular degeneration.

Abstract translation: 生物相容的微粒包括眼科活性的环状脂质组分和可生物降解的聚合物，当放置在结膜下空间中时，有效地促进环状脂质成分延长眼睛部分的时间。 环状脂质组分可与可生物降解的聚合物基质相结合，例如两种可生物降解聚合物的基质。 或者，环状脂质组分可以被聚合物组分包封。 本发明的微粒包括水包油乳化微粒。 结膜下施用的微粒可用于治疗或减少眼部疾病如青光眼或年龄相关性黄斑变性的至少一种症状。