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公开(公告)号:US20230167465A1
公开(公告)日:2023-06-01
申请号:US17799027
申请日:2021-02-22
Applicant: SUMITOMO RUBBER INDUSTRIES, LTD. , TOHOKU UNIVERSITY , KANAZAWA UNIVERSITY
Inventor: Haruhiko YAMAGUCHI , Yukino INOUE , Kazuhisa FUSHIHARA , Seiji TAKAHASHI , Toru NAKAYAMA , Satoshi YAMASHITA
CPC classification number: C12P5/007 , C12N9/1085 , C12Y205/01028 , C12Y205/01089
Abstract: The present disclosure provides a method for producing a polyisoprenoid, which makes it possible to synthesize in vitro a polyisoprenoid having an unprecedented structure, such as a 100% cis-polyisoprenoid or a polyisoprenoid containing an allylic diphosphate derivative as an initiating terminal. The present disclosure relates to a method for producing a polyisoprenoid in vitro, which employs a gene coding for a neryl diphosphate synthase and rubber particles bound to a protein encoded by the gene, or a method for producing a polyisoprenoid, which includes introducing into a plant a vector in which a gene coding for a neryl diphosphate synthase is linked to a promoter having a promoter activity that drives laticifer-specific gene expression to express a protein encoded by the gene specifically in laticifers.
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公开(公告)号:US20230067211A1
公开(公告)日:2023-03-02
申请号:US17799540
申请日:2020-12-22
Applicant: TOYODA GOSEI CO., LTD. , KYOTO UNIVERSITY , NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY
Inventor: Hideki TAMAI , Takanori NAKAI , Hideyuki IMAI , Makoto ISHIDA , Tomoki OGOSHI , Koki MAEDA , Katsuto ONISHI , Tada-Aki YAMAGISHI , Takahiro KAKUTA , Masafumi YAGYU
IPC: C08G65/26
Abstract: A polyrotaxane of high heat resistance contains a linear molecule, a cyclic molecule enclosing the linear molecule such that the cyclic molecule is skewered with the linear molecule, and 5 blocking groups disposed at both ends of the linear molecule. The cyclic molecule contains an aromatic ring having, on a side chain, a phenolic hydroxyl group. The polyrotaxane can be produced by dissolving, in a methanol-containing solvent, a linear molecule and a cyclic 10 molecule containing an aromatic ring having, on a side chain, a phenolic hydroxyl group, to yield a pseudo polyrotaxane in which the cyclic molecule encloses the linear molecule such that the cyclic molecule is skewered with the linear molecule; and dissolving the pseudo polyrotaxane and a blocking group 15 material in a solvent, to dispose blocking groups at both ends of the linear molecule.
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公开(公告)号:US20220162561A1
公开(公告)日:2022-05-26
申请号:US17601076
申请日:2020-04-03
Inventor: Kazutaka MATOBA , Katsuhiko KIDA , Taito NISHINO , Rikinari HANAYAMA , Takeshi YOSHIDA
IPC: C12N5/0775
Abstract: Provided is a composition for promoting secretion of extracellular vesicles, which comprises a compound having a structure of the formula I (wherein each substituent is as defined in the specification), a racemate thereof or a stereoisomer thereof, or a salt thereof, or a compound having a structure of the formula II (wherein each substituent is as defined in the specification), or a stereoisomer thereof, or a salt thereof, or, cucurbitacin, or a stereoisomer thereof, or a salt thereof.
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公开(公告)号:US20220141946A1
公开(公告)日:2022-05-05
申请号:US17435665
申请日:2019-03-01
Inventor: Yasunori TANAKA , Naoto KODAMA , Kazuki ONDA , Shu WATANABE , Keitaroh NAKAMURA , Shiori SUEYASU , Tomoya WATANABE
IPC: H05H1/30 , B01J19/08 , C01B33/021
Abstract: A fine particle manufacturing apparatus and a fine particle manufacturing method are provided. The apparatus includes a raw material supply part supplying a raw material; a plasma torch in which the thermal plasma flame is generated and the raw material supplied by the raw material supply part is vaporized by using the thermal plasma flame to form a mixture in a gas phase state; and a plasma generation part generating the thermal plasma flame inside the plasma torch. The plasma generation part includes a first coil encircling the plasma torch; a second coil encircling the plasma torch and disposed below the first coil; a first power supply part supplying a high-frequency electric current to the first coil; and a second power supply part supplying an amplitude-modulated high-frequency electric current to the second coil. The first coil and the second coil are arranged in the longitudinal direction of the plasma torch.
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公开(公告)号:US20210373030A1
公开(公告)日:2021-12-02
申请号:US17286355
申请日:2019-10-17
Inventor: Masashi MITA , Takashi WADA , Kengo FURUICHI , Norihiko SAKAI , Yasunori IWATA , Shinji KITAJIMA , Yusuke NAKADE
Abstract: The present invention provides: a marker for determining critical stage kidney disease by using an indicator value based on the amount of D-alanine in the blood or the amount of D-alanine and L-alanine therein; a blood analysis method which uses said marker for patients undergoing surgery or intensive care; and a blood analysis system for determining critical stage kidney disease in patients undergoing surgery or intensive care.
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公开(公告)号:US20210283082A1
公开(公告)日:2021-09-16
申请号:US16972906
申请日:2019-06-06
Inventor: Takashi WADA , Kengo FURUICHI , Norihiko SAKAI , Yasunori IWATA , Akinori HARA , Yusuke NAKADE , Kenji HAMASE , Masashi MITA
IPC: A61K31/198 , A61P13/12 , A61K9/00
Abstract: The present invention pertains to a pharmaceutical composition for the prevention or treatment of kidney disease, an inflammation inhibitor for the kidneys, an inflammatory cell death inhibitor for the kidneys, or a food for the prevention or improvement of kidney disease, that include D-serine or a derivative thereof. In addition, the present invention pertains to the use of D-serine or a derivative thereof, for the production of a pharmaceutical composition for the prevention or treatment of kidney disease.
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公开(公告)号:US20200263007A1
公开(公告)日:2020-08-20
申请号:US15998647
申请日:2017-02-14
Inventor: kIYOSHI NISHIOKA , Masahiro SUZUKI , Koh-hei NITTA , Miho MAE
Abstract: Provided are a polyolefin-based resin composition having excellent antistatic performance, and a polyolefin-based resin film formed using the composition. More specifically, a polyolefin-based resin composition comprising a polyolefin-based resin, a polyalkylene carbonate resin, and a metal salt having a melting point higher than 100° C. is provided. Also provided is a polyolefin-based resin film formed using the polyolefin-based resin composition, the film being stretched at least uniaxially.
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公开(公告)号:US10323101B2
公开(公告)日:2019-06-18
申请号:US15521200
申请日:2015-10-23
Inventor: Ryohei Kakuchi , Kazuaki Ninomiya , Yoshiki Shibata , Kiyoshi Uzawa , Tomoki Ogoshi , Katsuhiro Maeda , Tomoyuki Ikai , Kenji Takahashi
Abstract: An object is to provide a method for producing a polysaccharide derivative without using a catalyst, a cocatalyst, or an active compound by esterification, etherification, or the like, from a polysaccharide such as cellulose as a source material, while maintaining a high molecular weight. Another object is to provide a method for producing a cellulose derivative in a separated condition directly from biomass containing lignocellulose. A method for producing a polysaccharide derivative of the present invention is characterized in that a reaction is carried out in a mixture comprising: a source material comprising a polysaccharide; an ionic liquid for which the pKa of a conjugate acid of an anion in DMSO is 12 to 19 and which is capable of producing a carbene; and a chain or cyclic ester compound or an epoxy compound. Preferably as a source material containing a polysaccharide, a biomass source material containing lignocellulose is used.
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公开(公告)号:US10253426B2
公开(公告)日:2019-04-09
申请号:US15445134
申请日:2017-02-28
Applicant: SHIN-ETSU CHEMICAL CO., LTD. , National Institute of Advanced Industrial Science and Technology , NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY
Inventor: Hitoshi Noguchi , Shozo Shirai , Toshiharu Makino , Masahiko Ogura , Hiromitsu Kato , Hiroyuki Kawashima , Daisuke Kuwabara , Satoshi Yamasaki , Daisuke Takeuchi , Norio Tokuda , Takao Inokuma , Tsubasa Matsumoto
IPC: C23C16/27 , C30B25/04 , H01L21/02 , C30B25/18 , C30B25/20 , C30B29/04 , H01L29/16 , H01L21/3065 , H01L21/308
Abstract: A method for manufacturing a diamond substrate, including: a first step of preparing patterned diamond on a foundation surface, a second step of growing diamond from the patterned diamond prepared in the first step to form the diamond in a pattern gap of the patterned diamond prepared in the first step, a third step of removing the patterned diamond prepared in the first step to form a patterned diamond composed of the diamond formed in the second step, and a fourth step of growing diamond from the patterned diamond formed in the third step to form the diamond in a pattern gap of the patterned diamond formed in the third step. There can be provided a method for manufacturing a diamond substrate which can sufficiently suppress dislocation defects, a high-quality diamond substrate, and a freestanding diamond substrate.
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公开(公告)号:US20180244991A1
公开(公告)日:2018-08-30
申请号:US15755359
申请日:2016-08-24
Applicant: NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY , NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
Inventor: Yusuke HIEJIMA , Hiromichi HAYASHI , Mitsuhiro KANAKUBO
IPC: C09K11/65
Abstract: An object is to provide a method of manufacturing luminescent nanocarbon with which the luminescent nanocarbon can be efficiently manufactured in large amounts. This method is to manufacture luminescent nanocarbon (Product) from a raw material aqueous solution that contains a carbon source compound and a nitrogen source compound. This method includes a reaction step of heating the raw material aqueous solution from a storage container (Reservoir) in a heating section (Furnace) to react the raw material aqueous solution at a reaction temperature of 100° C. or higher and 500° C. or lower and a cooling step of cooling a reaction solution that contains a reaction product generated in the reaction step. The cooling step is carried out in a bath (Ice bath).
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