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公开(公告)号：US11814617B2
公开(公告)日：2023-11-14
申请号：US16756482
申请日：2018-10-19
Inventor： James Scott Drouillard , Kevin Alan Miller , Celine Caroline Aperce , Taylor Marie Horne , Tara Jo Ellerman , Gina Rae Herren
CPC classification number: C12N1/20 , A01N63/20 , A23K30/18 , C12N1/205 , C12R2001/01
Abstract: The present invention relates to methods of producing ensiled plant materials using the anaerobic bacterium Megasphaera elsdenii and ensiled plant materials thereof.
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公开(公告)号：US11751943B2
公开(公告)日：2023-09-12
申请号：US16477490
申请日：2018-01-26
Applicant: Kansas State University Research Foundation
Inventor： Punit Prakash , Austin Pfannenstiel
CPC classification number: A61B18/1815 , A61B1/018 , A61B1/2676 , A61B2018/00023 , A61B2018/00541 , A61B2018/00577 , A61B2018/00642 , A61B2018/00785 , A61B2018/00791 , A61B2018/00982 , A61B2018/1823 , A61B2018/1838 , A61B2018/1853 , A61B2018/1861
Abstract: A novel monitoring method evaluates tissue ablation progress. An antenna in a distal portion of an ablation applicator sends and receives electrical information from the target tissue during ablation. The information is used to determine ablation progress. A related ablation monitoring system includes a power monitor and processor operable to evaluate ablation progress based on reflected electrical properties during the ablation. The invention has particular benefits when used in endoscopic-based microwave ablation.
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13.发明公开公开(公告)号：US20230258640A1
公开(公告)日：2023-08-17
申请号：US18051422
申请日：2022-10-31
Applicant: HAWKEYE BIO, LIMITED , THE UNIVERSITY OF KANSAS , KANSAS STATE UNIVERSITY RESEARCH FOUNDATION
Inventor： Paul W. DEMPSEY , Spencer HANTULA , Cristina-Mihaela Sandu APARICIO , Stefan H. BOSSMANN , Christopher M. SORENSEN , Obdulia COVARRUBIAS-ZAMBRANO , Jose COVARRUBIAS
IPC: G01N33/573 , G01N33/543 , G01N33/542 , G01N33/533 , G01N33/551
CPC classification number: G01N33/573 , G01N33/54346 , G01N33/542 , G01N33/533 , G01N33/551
Abstract: Provided herein are graphene biosensors and related core particles, compositions methods and systems in which more than one pristine graphene sheet is coated with a coating layer of an organic or inorganic material to provide a core graphene particle, to which detectable components comprising a detectable moiety and a peptide linkage are attached through binding of the peptide linkage.
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公开(公告)号：US20230191436A1
公开(公告)日：2023-06-22
申请号：US17559326
申请日：2021-12-22
Inventor： Andrew W. Harmon , Ajay Sharda , Jonathan Fabula
CPC classification number: B05B12/084 , A01M7/0089 , B05B1/20 , B05B12/12 , A01C23/047
Abstract: An agricultural system can include a first nozzle assembly positioned along a boom assembly and configured to selectively dispense an agricultural product therefrom. An airflow detection system can be configured to capture data indicative of one or more airflow sources. A computing system can be communicatively coupled to the first nozzle assembly and the airflow detection system. The computing system can be configured to receive, from the airflow detection system, the data associated with the one or more airflow sources and generate a first nozzle vector for the first nozzle assembly based at least in part on the data from the airflow detection system.
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公开(公告)号：US20230189785A1
公开(公告)日：2023-06-22
申请号：US17559368
申请日：2021-12-22
Inventor： Andrew W. Harmon , Ajay Sharda , Jonathan Fabula
CPC classification number: A01M7/0089 , A01M7/0042 , B05B12/082 , G05B15/02 , B05B12/12 , B05B12/085 , B05B1/20
Abstract: A method for an agricultural application operation is provided herein. The method includes receiving a target application condition for an agricultural product to be exhausted from a nozzle assembly through an input device. The method also includes receiving an agricultural product flow condition and data related to boom movement from a sensing system. In addition, the method includes receiving a first duty cycle from a computing system. The method further includes determining a detected application condition based on the agricultural product flow condition, the data related to boom movement, and the first duty cycle with the computing system. Lastly, the method includes generating a duty cycle command based on a comparison of the target application condition to the detected application condition with the computing system.
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Patent Agency Ranking
公开(公告)号：US20230167159A1
公开(公告)日：2023-06-01
申请号：US17906825
申请日：2021-03-22
Applicant: Kansas State University Research Foundation
Inventor： Waithaka Mwangi , Huldah Sang
IPC: C07K14/165 , C12N15/86
CPC classification number: C07K14/165 , C12N15/86 , C12N2770/20034 , A61K2039/53
Abstract: A new species of coronavirus, SARS-CoV-2, is the cause of a worldwide pandemic and has resulted in hundreds of thousands of deaths. The present disclosure provides immunological compositions and methods related to the production and administration of such compositions to reduce the severity of, incidence of and transmissibility of SARS-CoV-2.
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公开(公告)号：US11600399B2
公开(公告)日：2023-03-07
申请号：US17270537
申请日：2019-08-23
Applicant: Kansas State University Research Foundation
Inventor： Walter McNeil , Amir Bahadori , Diego Laramore
Abstract: Microsized devices operable to emit neutrons in a selective manner are provided. The devices are configured so that the rate of neutron emission can be varied, either actively or passively. The devices comprise an a-particle emitting material and a neutron producing target material that when aligned and/or positioned a predetermined distance apart emit neutrons. The rate of neutron emission can be slowed or stopped by taking the materials out of alignment and/or attenuating the α-particles being directed toward the neutron producing target material.
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公开(公告)号：US20220356492A1
公开(公告)日：2022-11-10
申请号：US17635036
申请日：2020-08-14
Applicant: Kansas State University Research Foundation
Inventor： Kristopher Silver , Yoonseong Park
Abstract: Nucleic acid delivery vehicles for delivering nucleic acid, e.g., for RNAi to cells that are typically refractory to RNAi by using extracellular vesicles (EVs) from cultured beetle cells as delivery vehicles. Instead of using high levels of long dsRNA and transfection reagents to accomplish suppression of an mRNA target in cells that don't respond to treatment with naked dsRNA, this approach applies the dsRNA to cultured beetle cells, collects nucleic-acid loaded EVs from the culture, then treats our target cells with the intracellularly loaded EVs, which results in significant enhancement of the RNAi response and greater suppression of transcript levels.
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公开(公告)号：US20220073999A1
公开(公告)日：2022-03-10
申请号：US17514724
申请日：2021-10-29
Inventor： Mei He
IPC: C12Q1/6886 , A61K47/69 , G01N33/574 , G01N33/543 , B03C1/015 , B03C1/30 , B01L3/00 , A61K49/00
Abstract: Methods for producing engineered exosomes and other vesicle-like biological targets, including allowing a target vesicle-like structure to react and bind with immunomagnetic particles; capturing the immunomagnetic particle/vesicle complex by applying a magnetic field; further engineering the captured vesicles by surface modifying with additional active moieties or internally loading with active agents; and releasing the engineered vesicle-like structures, such as by photolytically cleaving a linkage between the particle and engineered vesicle-like structures, thereby releasing intact vesicle-like structures which can act as delivery vehicles for therapeutic treatments.
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公开(公告)号：US20220024877A1
公开(公告)日：2022-01-27
申请号：US17277631
申请日：2019-09-20
Inventor： Stefan H. Bossmann , Madumali Kalubowilage , Man Zhang , Anjana Delpe-Acharige , Kayla Eschliman , Frank Wolschendorf , Olaf Kutsch , Alex Dalecki , Whitney Narmore
IPC: C07D231/42 , C07D231/22 , A61K45/06 , A61P31/04
Abstract: Heterocyclic compounds with a novel pyrazole thioamide-based NNSN structural motif, having highly effective zinc- or copper-activated toxicity against microbial infections at micromolar or nanomolar minimum inhibitory concentrations (MIC), and methods of making and using same.
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