-
公开(公告)号：US11609328B2
公开(公告)日：2023-03-21
申请号：US16411951
申请日：2019-05-14
发明人： Guy Satat , Ramesh Raskar
摘要： A light source may illuminate a scene that is obscured by fog. Light may reflect back to a time-resolved light sensor. For instance, the light sensor may comprise avalanche photodiodes that are not single-photon sensitive. The light sensor may perform a raster scan. The imaging system may determine reflectance and depth of the fog-obscured target. The imaging system may perform a probabilistic algorithm that exploits the fact that times of arrival of photons reflected from fog have a Gamma distribution that is different than the Gaussian distribution of times of arrival of photons reflected from the target. The imaging system may adjust frame rate locally depending on local density of fog, as indicated by a local Gamma distribution determined in a prior step. The imaging system may perform one or more of spatial regularization, temporal regularization, and deblurring.
-
公开(公告)号：US11605834B2
公开(公告)日：2023-03-14
申请号：US17118359
申请日：2020-12-10
发明人： Jeremiah Allen Johnson , Yang Shao-Horn , Robinson Anandakathir , Mao Chen , Shuting Feng , Livia Giordano , Mingjun Huang , Wenxu Zhang
IPC分类号： H01M10/0565 , C07C311/13 , H01M10/0568 , H01M10/052 , C07C311/48 , C07C311/15
摘要： A class of sulfonimide salts for solid-state electrolytes can be synthesized based on successive SNAr reactions of fluorinated phenyl sulfonimides: Fluorinated Aryl Sulfonimide Tags (FAST). The chemical and electrochemical oxidative stability of these FAST salts as well as other properties like solubility, Lewis basicity, and conductivity can be tuned by introducing different numbers and types of nucleophilic functional groups to the FAST salt scaffold.
-
13.发明授权公开(公告)号：US11603597B2
公开(公告)日：2023-03-14
申请号：US16450847
申请日：2019-06-24
摘要： Systems and methods for electrochemically producing chemical products are provided. In certain cases, the systems and methods described herein are capable of producing chemical products such as hydrogen peroxide in solutions with relatively low concentrations of electrolyte or other dissolved species at high efficiencies and/or low energetic cost. In some cases, redox mediators are used to spatially decouple direct electrochemical processes from the production of the chemical product.
-
公开(公告)号：US11603396B2
公开(公告)日：2023-03-14
申请号：US17548247
申请日：2021-12-10
发明人： Robert Alexander Wesselhoeft , Daniel G. Anderson , Shinichiro Fuse , Brian Goodman , Allen T. Horhota , Raffaella Squilloni
摘要： Circular RNA and transfer vehicles, along with related compositions and methods are described herein. In some embodiments, the inventive circular RNA comprises group I intron fragments, spacers, an IRES, duplex forming regions, and an expression sequence. In some embodiments, the expression sequence encodes a chimeric antigen receptor (CAR). In some embodiments, circular RNA of the invention has improved expression, functional stability, immunogenicity, ease of manufacturing, and/or half-life when compared to linear RNA. In some embodiments, inventive methods and constructs result in improved circularization efficiency, splicing efficiency, and/or purity when compared to existing RNA circularization approaches.
-
公开(公告)号：US11602886B2
公开(公告)日：2023-03-14
申请号：US16773313
申请日：2020-01-27
发明人： Anastasios John Hart , Sebastian William Pattinson , Meghan Elizabeth Huber , Jongwoo Lee , Ricardo Roberts
摘要： Wearable and implantable devices that are used to support human anatomy and are formed using additive manufacturing are provided. Systems and methods for performing additive manufacturing allow for the formulation of a mesh material that has localized stiffness and slack in regions to best serve the needs of the patient. For example, regions of the mesh material can be designed to rigidly support portions of human anatomy, such as injured tissue, while regions of the mesh material adjacent to the injured tissue can be designed to closely mimic movement of the relevant human anatomy. For example, the mesh material can be formed in a manner such that it does not fold in those regions, and therefore is not obtrusive. The present disclosure allows for control of toolpaths when printing fibers used to form the devices. Other devices, as well as systems and methods for creating the same, are also provided.
-
16.发明授权公开(公告)号：US11602716B2
公开(公告)日：2023-03-14
申请号：US17681413
申请日：2022-02-25
摘要： The removal of acid gases (e.g., non-carbon dioxide acid gases) using sorbents that include salts in molten form, and related systems and methods, are generally described.
-
公开(公告)号：US20230074840A1
公开(公告)日：2023-03-09
申请号：US17554314
申请日：2021-12-17
申请人： The Broad Institute, Inc. , Massachusetts Institute of Technology , President and Fellows of Harvard College
IPC分类号： C12Q1/6832 , C12N15/11 , C12N9/22 , C12N15/113 , C12Q1/6816
摘要： The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered DNA-targeting systems comprising a novel DNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA. Methods for making and using and uses of such systems, methods, and compositions and products from such methods and uses are also disclosed and claimed.
-
公开(公告)号：US20230061974A1
公开(公告)日：2023-03-02
申请号：US17939528
申请日：2022-09-07
IPC分类号： A61K47/18 , A61K9/19 , A61K31/7088 , A61K9/00 , C12N15/88 , C08G73/02 , A61K9/12 , A61K47/32 , A61K47/34 , C08G63/685
摘要： Provided herein are branched poly(beta-amino esters) (PBAE) useful as vehicles for the delivery of therapeutic agents, such as nucleic acids. The disclosed polymers form stable compositions, and are suitable for the delivery of therapeutic agents via nebulization. Compositions of the disclosed polymers are capable of delivering therapeutic agents such as mRNA to lung epithelial cells.
-
公开(公告)号：US11594885B2
公开(公告)日：2023-02-28
申请号：US17185248
申请日：2021-02-25
发明人： Brice MacLaren , James Macomber , Megan Richardson
摘要： In one aspect, a method to determine a capacity of a microgrid includes applying a current test load to the microgrid and measuring a current through an energy storage device, the current indicating a charging status of the energy storage device based on a current load being applied to the microgrid through activated power outlets being served by the microgrid and the current test load, the energy storage device being integrated with the microgrid. The method also includes, responsive to a determination that the measured current based on the current load being applied to the microgrid and the current test load indicates that the energy storage device is discharging, determining the capacity of the microgrid, wherein the capacity is the current load being applied to the microgrid through activated power outlets and a test load applied to the microgrid immediately preceding the current test load.
-
公开(公告)号：US11593512B2
公开(公告)日：2023-02-28
申请号：US16612993
申请日：2018-05-11
发明人： Zhizhuo Zhang , Manolis Kellis , Dianbo Liu , Anne Kim , Lauren Huang , Sandeep Nuckchady
IPC分类号： G06F21/62 , G16H10/40 , G16H50/30 , G16H50/70 , G06F16/23 , G16B30/10 , G16B20/20 , G16B20/40 , G16B50/40 , G06F9/455 , G06F21/60 , G06Q50/26 , H04L9/30
摘要： Described herein are a secure system for sharing private data and related systems and methods for incentivizing and validating private data sharing. In some embodiments, private data providers may register to selectively share private data under controlled sharing conditions. The private data may be cryptographically secured using encryption information corresponding to one or more secure execution environments. To demonstrate to the private data providers that the secure execution environment is secure and trustworthy, attestations demonstrating the security of the secure execution environment may be stored in a distributed ledger (e.g., a public blockchain). Private data users that want access to shared private data may publish applications for operating on the private data to a secure execution environment and publish, in a distributed ledger, an indication that the application is available to receive private data. The distributed ledger may also store sharing conditions under which the private data will be shared.
-
-
-
-
-
-
-
-
-
搜索结果
6544 条记录 (耗时 0.075 秒)