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公开(公告)号：US5482947A
公开(公告)日：1996-01-09
申请号：US152934
申请日：1993-11-15
Applicant: John J. Talley , Daniel P. Getman , Gary A. DeCrescenzo , Ko-Chung Lin , Michael L. Vazquez , Richard A. Mueller , Kathryn L. Reed , Robert M. Heintz , Michael Clare , John N. Freskos , Eric T. Sun
Inventor： John J. Talley , Daniel P. Getman , Gary A. DeCrescenzo , Ko-Chung Lin , Michael L. Vazquez , Richard A. Mueller , Kathryn L. Reed , Robert M. Heintz , Michael Clare , John N. Freskos , Eric T. Sun
IPC: A61K31/17 , A61K31/195 , A61K31/197 , A61K31/216 , A61K31/27 , A61K31/47 , A61K31/4709 , A61K31/496 , A61K31/5377 , A61K38/00 , C07C213/00 , C07C213/02 , C07C213/08 , C07C215/28 , C07C269/06 , C07C271/16 , C07C271/20 , C07C271/22 , C07C275/14 , C07C275/18 , C07C275/22 , C07C275/24 , C07C275/28 , C07C311/47 , C07C317/44 , C07C317/50 , C07C323/60 , C07C329/06 , C07C335/08 , C07C335/12 , C07D213/81 , C07D215/48 , C07D215/50 , C07D215/54 , C07D217/26 , C07D235/06 , C07D235/24 , C07D239/38 , C07D241/44 , C07D295/13 , C07D295/15 , C07D303/36 , C07D307/85 , C07D401/12 , C07K5/02 , C07K5/06 , C07K5/078
CPC classification number: C07K5/06191 , A61K31/17 , A61K31/195 , A61K31/197 , A61K31/216 , A61K31/27 , A61K31/47 , A61K31/4709 , A61K31/496 , A61K31/5377 , C04B35/632 , C07C213/00 , C07C213/02 , C07C213/08 , C07C269/06 , C07C271/20 , C07C271/22 , C07C275/14 , C07C275/18 , C07C275/22 , C07C275/24 , C07C275/28 , C07C311/47 , C07C317/44 , C07C317/50 , C07C323/60 , C07C329/06 , C07C335/08 , C07C335/12 , C07D213/81 , C07D215/48 , C07D215/50 , C07D215/54 , C07D217/26 , C07D235/06 , C07D235/24 , C07D239/38 , C07D241/44 , C07D295/13 , C07D295/15 , C07D303/36 , C07D307/85 , C07D401/12 , C07K5/0207 , C07K5/021 , C07K5/06026 , C07K5/06139 , A61K38/00 , C07B2200/07 , C07C2101/02 , C07C2101/04 , C07C2101/08 , C07C2101/14
Abstract: Urea-containing hydroxyethylamine compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
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公开(公告)号：USD1046353S1
公开(公告)日：2024-10-08
申请号：US29831623
申请日：2022-03-22
Applicant: Michael Clare
Designer： Michael Clare
Abstract: FIG. 1 is a front perspective view of the golf glove drying device;
FIG. 2 is a back perspective view thereof;
FIG. 3 is a back view thereof;
FIG. 4 is a right side view thereof;
FIG. 5 is a left side view thereof;
FIG. 6 is a top view thereof;
FIG. 7 is a front view thereof; and,
FIG. 8 is a bottom view thereof.
Longer broken lines represent stitching. The shorter broken lines represent portions of the golf glove drying device that form no part of the claimed design.-
公开(公告)号：US20080103311A1
公开(公告)日：2008-05-01
申请号：US12000244
申请日：2007-12-11
Applicant: John Tally , Daniel Getman , Gary DeCrescenzo , Kathryn Reed , Ko-Chung Lin , John Freskos , Michael Clare , Donald Rogier , Robert Heintz , Michael Vazquez , Richard Mueller
Inventor： John Tally , Daniel Getman , Gary DeCrescenzo , Kathryn Reed , Ko-Chung Lin , John Freskos , Michael Clare , Donald Rogier , Robert Heintz , Michael Vazquez , Richard Mueller
IPC: C07D217/00 , C07C233/00
CPC classification number: C07D401/12 , C07D211/60 , C07D217/26
Abstract: N-heterocyclic moiety containing hydroxyethylamino compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
Abstract translation: 含有羟基乙基氨基化合物的N-杂环部分作为逆转录病毒蛋白酶抑制剂是有效的，特别是作为HIV蛋白酶的抑制剂。
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公开(公告)号：US07312333B2
公开(公告)日：2007-12-25
申请号：US11331344
申请日：2006-01-13
Applicant: John J. Talley , Daniel P. Getman , Gary A. DeCrescenzo , Kathryn L. Reed , Ko-Chung Lin , John N. Freskos , Michael Clare , Donald J. Rogier, Jr. , Robert M. Heintz , Michael L. Vazquez , Richard A. Mueller
Inventor： John J. Talley , Daniel P. Getman , Gary A. DeCrescenzo , Kathryn L. Reed , Ko-Chung Lin , John N. Freskos , Michael Clare , Donald J. Rogier, Jr. , Robert M. Heintz , Michael L. Vazquez , Richard A. Mueller
IPC: C07D471/00
CPC classification number: C07D401/12 , C07D207/16 , C07D211/60 , C07D217/26
Abstract: N-heterocyclic moiety containing hydroxyethylamine compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
Abstract translation: 含有羟基胺化合物的N-杂环部分作为逆转录病毒蛋白酶抑制剂是有效的，特别是作为HIV蛋白酶抑制剂。
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公开(公告)号：US07112683B2
公开(公告)日：2006-09-26
申请号：US10932331
申请日：2004-09-02
Applicant: Deborah E. Bertenshaw , Daniel P. Getman , Robert M. Heintz , John J. Talley , Kathryn L. Reed , Robert A. Chrusciel , Michael Clare
Inventor： Deborah E. Bertenshaw , Daniel P. Getman , Robert M. Heintz , John J. Talley , Kathryn L. Reed , Robert A. Chrusciel , Michael Clare
IPC: C07D221/18 , C07D221/22
CPC classification number: C07D333/48 , C07D231/12 , C07D233/56 , C07D249/08 , C07D279/12 , C07D335/02 , C07D409/12
Abstract: The present invention relates to cyclic sulfone moiety-containing hydroxyethylamine protease inhibitor compounds and pharmaceutical or method of use therefor, particularly as an inhibitor of HIV protease.
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Patent Agency Ranking
公开(公告)号：US20050119257A1
公开(公告)日：2005-06-02
申请号：US10932331
申请日：2004-09-02
Applicant: Deborah Bertenshaw , Daniel Getman , Robert Heintz , John Talley , Kathryn Reed , Robert Chrusciel , Michael Clare
Inventor： Deborah Bertenshaw , Daniel Getman , Robert Heintz , John Talley , Kathryn Reed , Robert Chrusciel , Michael Clare
IPC: A61K31/38 , A61K31/381 , A61K31/382 , A61K31/415 , A61K31/425 , A61K31/4433 , A61K31/445 , A61K31/54 , A61P31/12 , A61P43/00 , C07D279/12 , C07D283/00 , C07D333/48 , C07D335/02 , C07D409/12 , C07D417/12 , C07D521/00 , C07D417/02 , C07D49/02
CPC classification number: C07D333/48 , C07D231/12 , C07D233/56 , C07D249/08 , C07D279/12 , C07D335/02 , C07D409/12
Abstract: The present invention relates to cyclic sulfone moiety-containing hydroxyethylamine protease inhibitor compounds and pharmaceutical or method of use therefor, particularly as an inhibitor of HIV protease.
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公开(公告)号：US06833366B1
公开(公告)日：2004-12-21
申请号：US10657932
申请日：2003-09-09
Applicant: Thomas Rogers , Michael Clare , Hwang-Fun Lu , Mark Russell , James W. Malecha , Ish Kumar Khanna , Thomas Penning , Srinivasan Raj Nagarajan
Inventor： Thomas Rogers , Michael Clare , Hwang-Fun Lu , Mark Russell , James W. Malecha , Ish Kumar Khanna , Thomas Penning , Srinivasan Raj Nagarajan
IPC: A61K3133
CPC classification number: C07D213/74 , C07D239/14 , C07D401/12
Abstract: The present invention relates to a class of compounds represented by the Formula 1. or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula 1, and methods of selectively inhibiting or antagonizing the &agr;v&bgr;3 and/or the &agr;v&bgr;5 integrin.
Abstract translation: 本发明涉及一类由式1表示的化合物或其药学上可接受的盐，包含式1的化合物的药物组合物，以及选择性抑制或拮抗阿尔法博三唑和/或阿尔法肽5整联蛋白的方法。
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公开(公告)号：US06617324B1
公开(公告)日：2003-09-09
申请号：US10114297
申请日：2002-04-02
Applicant: Ashok S. Naraian , Michael Clare , Paul W. Collins , Joyce Zuowu Crich , Rajesh Devraj , Daniel L. Flynn , Lifeng Geng , Matthew J. Graneto , Cathleen E. Hanau , Gunnar J. Hanson , Susan J. Hartmann , Michael Hepperle , He Huang , Francis J. Koszyk , Shuyuan Liao , Suzanne Metz , Richard A. Partis , Thao D. Perry , Shashidhar N. Rao , Shaun Raj Selness , Michael S. South , Michael A. Stealey , John Jeffrey Talley , Michael L. Vazquez , Richard M. Weier , Xiangdong Xi , Ish K. Khanna , Yi Yu
Inventor： Ashok S. Naraian , Michael Clare , Paul W. Collins , Joyce Zuowu Crich , Rajesh Devraj , Daniel L. Flynn , Lifeng Geng , Matthew J. Graneto , Cathleen E. Hanau , Gunnar J. Hanson , Susan J. Hartmann , Michael Hepperle , He Huang , Francis J. Koszyk , Shuyuan Liao , Suzanne Metz , Richard A. Partis , Thao D. Perry , Shashidhar N. Rao , Shaun Raj Selness , Michael S. South , Michael A. Stealey , John Jeffrey Talley , Michael L. Vazquez , Richard M. Weier , Xiangdong Xi , Ish K. Khanna , Yi Yu
IPC: A61K31496
CPC classification number: C07D409/14 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/14 , C07D413/14 , C07D417/14 , C07D453/02 , C07D471/04 , C07D473/00 , C07D487/04
Abstract: A class of pyrazole derivatives described for use in treating p38 kinase mediated disorders. Compounds of particular interest are defined by Formula IA wherein R1, R2, R3 and R4 are as described in the specification.
Abstract translation: 一类描述用于治疗p38激酶介导的病症的吡唑衍生物。 特别感兴趣的化合物由式IA定义，其中R1，R2，R3和R4如说明书中所述。
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公开(公告)号：US06506759B1
公开(公告)日：2003-01-14
申请号：US09699515
申请日：2000-10-31
Applicant: John J. Talley , Daniel P. Getman , Gary A. DeCrescenzo , Kathryn L. Reed , Ko-Chung Lin , John Nicholas Freskos , Michael Clare , Donald Joseph Rogier, Jr. , Robert M. Heintz , Michael L. Vazquez , Richard A. Mueller
Inventor： John J. Talley , Daniel P. Getman , Gary A. DeCrescenzo , Kathryn L. Reed , Ko-Chung Lin , John Nicholas Freskos , Michael Clare , Donald Joseph Rogier, Jr. , Robert M. Heintz , Michael L. Vazquez , Richard A. Mueller
IPC: A01N4360
CPC classification number: C07D401/12 , C07D207/16 , C07D211/60 , C07D217/26
Abstract: N-heterocyclic moiety containing hydroxyethylamine compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
Abstract translation: 含有羟基胺化合物的N-杂环部分作为逆转录病毒蛋白酶抑制剂是有效的，特别是作为HIV蛋白酶抑制剂。
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公开(公告)号：US6087496A
公开(公告)日：2000-07-11
申请号：US283718
申请日：1999-04-01
Applicant: Ashok Anantanarayan , Michael Clare , Lifeng Geng , Gunnar J. Hanson , Richard A. Partis , Michael A. Stealey , Richard M. Weier
Inventor： Ashok Anantanarayan , Michael Clare , Lifeng Geng , Gunnar J. Hanson , Richard A. Partis , Michael A. Stealey , Richard M. Weier
IPC: A61K31/44 , A61K31/445 , A61K31/5377 , C07D401/04 , C07D401/14 , C07D403/04 , C07D413/04
CPC classification number: C07D401/04 , C07D401/14
Abstract: A class of pyrazole derivatives is described for use in treating p38 kinase mediated disorders. Compounds of particular interest are defined by Formula I: ##STR1## wherein R.sup.1, R.sup.2, Ar.sup.1 and HetAr.sup.2 are as described in the specification.
Abstract translation: 描述了一类吡唑衍生物用于治疗p38激酶介导的病症。 特别感兴趣的化合物由式I定义：其中R1，R2，Ar1和HetAr2如说明书中所述。
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