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公开(公告)号:US20220409229A1
公开(公告)日:2022-12-29
申请号:US17620765
申请日:2020-06-20
Inventor: Tohru TANI , Shigeyuki NAKA , Atsushi YAMADA
IPC: A61B17/3201 , A61B18/18
Abstract: Provided is a scissors-type medical treatment tool capable of not only local tissue fixation in an incision/cutting part but also heating on side surfaces of electrodes of a forceps/tweezers type. It has been found out that a tissue part in which tissue is nipped between blades and a tissue part which is brought into abutment against side surfaces of the blades can be heated simultaneously or sequentially by optimizing arrangement of microwave application electrodes and microwave receiver electrodes in a blade pair (in particular, by causing coagulation to be performed evenly on the left and right of the blades), and the present invention has therefore been achieved.
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公开(公告)号:US20220175410A1
公开(公告)日:2022-06-09
申请号:US17554386
申请日:2021-12-17
Inventor: Tohru TANI , Shigeyuki NAKA , Atsushi YAMADA , Tsuyoshi NAKAKUBO
IPC: A61B17/3201 , A61B17/28 , A61B17/29 , A61B34/30
Abstract: A cutting device including a first contact member and at second contact member assembled so as to be openable and closable, a contact mechanism that rotates the first contact member toward the second contact member to bring the first contact member and the second contact member into contact with a target portion, and a cutting mechanism for cutting the target portion in a state where the first contact member and the second contact member are in contact with the target portion by the contact mechanism.
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公开(公告)号:US10890513B2
公开(公告)日:2021-01-12
申请号:US15759719
申请日:2016-09-14
Applicant: NATIONAL UNIVERSITY CORPORATION SHIGA UNIVERSITY OF MEDICAL SCIENCE , JAPAN VILENE COMPANY, LTD.
Inventor: Ken-ichi Mukaisho , Takanori Hattori , Takuya Iwasa , Masaaki Kawabe , Satoshi Kumagai
Abstract: Provided are a cell-holding substrate holder for preparing an observation specimen, and a cell-holding substrate kit, wherein the cell-holding substrate can be easily attached and detached. Also provided is a method of preparing an observation specimen, wherein cell organelles can be satisfactorily observed using an optical microscope, while three problems of cell detachment, drying, and loss of the three-dimensional properties can be simultaneously solved. The cell-holding substrate holder comprises (1) a support plate 1 having a cell-holding substrate arrangement portion 12 having a window portion through which water can pass; and (2) a removable sandwiching plate 2, 3 which has a window portion through which water can pass, and is capable of working in conjunction with the support plate 1 to sandwich and fix a cell-holding substrate 9 in the cell-holding substrate arrangement portion 12. The cell-holding substrate kit 10 comprises the cell-holding substrate holder and a cell-holding substrate 9. In the preparation method, cells are collected with an inorganic fiber aggregate, wet-fixed as they are, stained, and mounted with a mounting medium having a refractive index equivalent to that of the inorganic fiber.
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公开(公告)号:US20190335977A1
公开(公告)日:2019-11-07
申请号:US16343990
申请日:2017-10-24
Inventor: Atsushi YAMADA , Tohru TANI , Shigeyuki NAKA , Shigehiro MORIKAWA
Abstract: A bending and extending device 1 comprises an elastic hollow guide unit 2 and a movable part 3 to be movably inserted into the guide unit 2. The movable part 3 is constituted, either partially or entirely, of a plurality of belt-like flexible parts 30a and 30b, which extend in the axial direction of the guide unit 2 and the flexible parts 30a and 30b are connected at distal ends. The bending and extending device 1 is characterized in that, when, by the sliding operation of the flexible parts 30a and 30b, a cross-section in which a contact point T of the flexible part 30a and the inner surface of the guide unit 2 is present on an extending line Y extending from a line segment connecting the centroid P of the flexible part 30b and the axial center G of the guide unit 2 and in which the flexible part 30a and the second flexible part 30b are in contact with each other is generated, and when the cross-section is divided into two ranges by a predetermined straight line X, the centroid P of the flexible part 30b is not positioned in a range in which the contact point T is present; and the predetermined straight line X is a line that passes through the axial center G of the guide unit 2, and that orthogonally crosses the extending line Y.
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公开(公告)号:US20170290623A1
公开(公告)日:2017-10-12
申请号:US15512647
申请日:2015-07-13
Inventor: Shinya MIKI , Megumi ADACHI , Toru TANI , Shigeyuki NAKA , Tomoharu SHIMIZU
CPC classification number: A61B18/1445 , A61B17/320068 , A61B18/1402 , A61B2017/00849 , A61B2017/320069 , A61B2017/320082 , A61B2018/0013 , A61B2018/00601 , A61B2018/00607 , A61B2018/0097 , A61B2018/1412 , A61B2018/1452 , A61B2018/1462 , A61L31/088 , A61L31/10 , A61L2420/08
Abstract: There is provided an energy device for surgical operation capable of suppressing fixation of body tissue, wherein a coating layer is formed on an outer periphery of a base material constituting an operational area portion transmitting energy in an energy device for surgical operation operating in the operational area portion, and is comprised of a base coating formed on the base material and an outermost coating formed on the base coating. The base coating is made from silicon oxide or a compound containing silicon oxide, and the outermost coating is made from polysiloxane or a compound containing polysiloxane or a compound containing a partly fluorinated polysiloxane, and the coating layer has a good adhesiveness and is applicable to a complicated form.
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公开(公告)号:US20250018188A1
公开(公告)日:2025-01-16
申请号:US18276689
申请日:2023-01-27
Inventor: Saburo MIKATA , Takayoshi ABE , Hisakazu OGITA
IPC: A61N1/36
Abstract: An electric potential therapy device includes a negative voltage applying means, an electrostatic charge removing means, and a controller that controls the negative voltage applying means and the electrostatic charge removing means in a predetermined therapy time in which a therapy cycle is repeated a plurality of times, the therapy cycle consisting of a first and second period. The negative voltage applying means includes a negative voltage generator and an application electrode. The negative voltage generated by the negative voltage generator is applied to the living body through the application electrode. The controller charges the living body to a negative potential in the first period by controlling the negative voltage applying means to apply the negative voltage to the living body, and puts the living body into a non-charged state by controlling the electrostatic charge removing means to remove electrostatic charges from inside the living body in the second period.
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公开(公告)号:US20230337899A1
公开(公告)日:2023-10-26
申请号:US18143451
申请日:2023-05-04
Inventor: Atsushi YAMADA , Tohru TANI
CPC classification number: A61B1/0052 , A61B1/00087 , A61B1/00133 , A61B34/30 , A61B1/0057 , A61B2034/302 , A61B2034/305 , A61B2034/301
Abstract: A movable elongated structure includes a distal end side tube, a base end side tube, traction wires, and a wiring aid routed by the traction wires arranged between the distal end side tube and the base end side tube, wherein the wiring aid guides the pair of traction wires from a pair of base end side wire lumens provided in the base end side tube to be introduced into a pair of distal end side wire lumens provided in the distal end side tube.
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公开(公告)号:US11414693B2
公开(公告)日:2022-08-16
申请号:US16615705
申请日:2018-05-24
Inventor: Shin-Ya Morita
Abstract: Disclosed is a method for quantifying phosphatidylinositol in a sample, comprising the following step: (1) treating the sample with phospholipase D and inositol dehydrogenase; and a kit for quantifying phosphatidylinositol, containing phospholipase D and inositol dehydrogenase.
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公开(公告)号:US20210381008A1
公开(公告)日:2021-12-09
申请号:US17262400
申请日:2019-07-26
Inventor: Hiroshi KAWAMOTO , Yasutoshi AGATA , Seiji NAGANO , Koji TERADA , Kyoko MASUDA
IPC: C12N15/90 , C12N5/0783 , C07K14/725 , A61K35/17
Abstract: Provided is a method for producing a cell incorporating an antigen specific receptor gene, which comprises the step of introducing an exogenous TCR or CAR gene into a material cell so that the introduced gene is expressed under the T cell receptor expression control system of the material cell.
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公开(公告)号:US20180340869A1
公开(公告)日:2018-11-29
申请号:US15759719
申请日:2016-09-14
Inventor: Ken-ichi MUKAISHO
IPC: G01N1/31 , G01N1/30 , G01N33/483 , G02B21/34
Abstract: Provided are a cell-holding substrate holder for preparing an observation specimen, and a cell-holding substrate kit, wherein the cell-holding substrate can be easily attached and detached. Also provided is a method of preparing an observation specimen, wherein cell organelles can be satisfactorily observed using an optical microscope, while three problems of cell detachment, drying, and loss of the three-dimensional properties can be simultaneously solved. The cell-holding substrate holder comprises (1) a support plate 1 having a cell-holding substrate arrangement portion 12 having a window portion through which water can pass; and (2) a removable sandwiching plate 2, 3 which has a window portion through which water can pass, and is capable of working in conjunction with the support plate 1 to sandwich and fix a cell-holding substrate 9 in the cell-holding substrate arrangement portion 12. The cell-holding substrate kit 10 comprises the cell-holding substrate holder and a cell-holding substrate 9. In the preparation method, cells are collected with an inorganic fiber aggregate, wet-fixed as they are, stained, and mounted with a mounting medium having a refractive index equivalent to that of the inorganic fiber.
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