Enhanced efficacy antiperspirant compositions containing strontium or calcium
    13.
    发明申请
    Enhanced efficacy antiperspirant compositions containing strontium or calcium 有权
    含有锶或钙的增效功效止汗组合物

    公开(公告)号:US20050036967A1

    公开(公告)日:2005-02-17

    申请号:US10641305

    申请日:2003-08-14

    摘要: Disclosed are enhanced efficacy antiperspirant compositions containing a strontium salt and/or a calcium salt. In particular, there is disclosed an antiperspirant composition comprising a dermatologically acceptable carrier vehicle, about 8% to about 22% (USP) of an aluminum-zirconium chlorohydrate-gly antiperspirant salt, wherein the antiperspirant salt has an HPLC peak 5 area of at least 33%, and about 0.5% to about 15%, preferably about 1% to about 6%, by weight, of a water soluble salt selected from the group consisting of a water soluble strontium salt, a water soluble calcium salt and a mixture thereof It has been found that the inclusion of a strontium salt and/or a calcium salt boosts the efficacy of a high peak 5 antiperspirant salt. As a preferred feature, the antiperspirant salt and the water soluble salt are dissolved in at least a portion of the carrier vehicle.

    摘要翻译: 公开了含有锶盐和/或钙盐的增强功效止汗组合物。 特别地,公开了一种止汗组合物,其包含皮肤病学上可接受的载体载体,约8%至约22%(USP)的一种水合氯化锆-Gan止汗剂盐,其中该止汗剂盐具有至少至少5个HPLC峰面积 33%,和约0.5%至约15%,优选约1%至约6%的选自水溶性锶盐,水溶性钙盐及其混合物的水溶性盐 已经发现,包含锶盐和/或钙盐提高了高峰5止汗剂盐的功效。 作为优选的特征,止汗剂盐和水溶性盐溶解在载体载体的至少一部分中。

    Stabilized antiperspirant compositions containing aluminum-zirconium salts with low M:Cl ratio
    14.
    发明授权
    Stabilized antiperspirant compositions containing aluminum-zirconium salts with low M:Cl ratio 有权
    含有低M:Cl比的铝 - 锆盐的稳定的止汗组合物

    公开(公告)号:US06726901B2

    公开(公告)日:2004-04-27

    申请号:US10142140

    申请日:2002-05-09

    IPC分类号: A61K732

    摘要: Disclosed is an anhydrous topical antiperspirant composition comprising a dermatologically acceptable carrier and a perspiration reducing effective amount of a particulate antiperspirant salt suspended in the carrier. The antiperspirant salt comprises an aluminum-zirconium chlorohydrate having a metal to chloride ratio between about 0.9 and about 1.3. The composition also includes, separate from the antiperspirant salt, a stabilizing basic material in an amount sufficient to prevent degradation of the antiperspirant composition or to minimize acid odor. Also disclosed is a method of reducing perspiration from human skin by applying the aforementioned topical composition.

    摘要翻译: 公开了一种无水局部止汗组合物,其包含皮肤病学可接受的载体和降低汗液的有效量的悬浮在载体中的颗粒止汗盐。 止汗盐包含金属氯化物比为约0.9至约1.3的水合氯化铝锆。 组合物还包括与止汗盐分开的稳定的碱性物质,其量足以防止止汗组合物的降解或使酸气味最小化。 还公开了通过应用上述局部组合物来减少人皮肤出汗的方法。

    Enhanced efficacy antiperspirant compositions containing strontium or calcium
    16.
    发明授权
    Enhanced efficacy antiperspirant compositions containing strontium or calcium 有权
    含有锶或钙的增效功效止汗组合物

    公开(公告)号:US06923952B2

    公开(公告)日:2005-08-02

    申请号:US10641305

    申请日:2003-08-14

    摘要: Disclosed are enhanced efficacy antiperspirant compositions containing a strontium salt and/or a calcium salt. In particular, there is disclosed an antiperspirant composition comprising a dermatologically acceptable carrier vehicle, about 8% to about 22% (USP) of an aluminum-zirconium chlorohydrate-gly antiperspirant salt, wherein the antiperspirant salt has an HPLC peak 5 area of at least 33%, and about 0.5% to about 15%, preferably about 1% to about 6%, by weight, of a water soluble salt selected from the group consisting of a water soluble strontium salt, a water soluble calcium salt and a mixture thereof. It has been found that the inclusion of a strontium salt and/or a calcium salt boosts the efficacy of a high peak 5 antiperspirant salt. As a preferred feature, the antiperspirant salt and the water soluble salt are dissolved in at least a portion of the carrier vehicle.

    摘要翻译: 公开了含有锶盐和/或钙盐的增强功效止汗组合物。 特别地,公开了一种止汗组合物,其包含皮肤病学上可接受的载体载体,约8%至约22%(USP)的一种水合氯化锆-Gan止汗剂盐,其中该止汗剂盐具有至少至少5个HPLC峰面积 33%,和约0.5%至约15%,优选约1%至约6%的选自水溶性锶盐,水溶性钙盐及其混合物的水溶性盐 。 已经发现,包含锶盐和/或钙盐提高了高峰5止汗剂盐的功效。 作为优选的特征,止汗剂盐和水溶性盐溶解在载体载体的至少一部分中。

    Aluminum-zirconium antiperspirant salts made with zirconium salts having low Zr:Cl ratio
    17.
    发明授权
    Aluminum-zirconium antiperspirant salts made with zirconium salts having low Zr:Cl ratio 有权
    由Zr:Cl比低的锆盐制成的铝 - 锆止汗盐

    公开(公告)号:US06663854B1

    公开(公告)日:2003-12-16

    申请号:US10175250

    申请日:2002-06-19

    IPC分类号: A61K732

    CPC分类号: A61K8/28 A61Q15/00 C01G25/006

    摘要: Disclosed are enhanced efficacy aluminum-zirconium chlorohydrate antiperspirant salts having a metal (Al+Zr) to chloride ratio of about 0.9 to about 1.2, preferably about 0.9 to about 1.1, most preferably about 0.9 to about 1.0. To achieve the highest possible antiperspirant efficacy, these salts are made with or include a zirconium hydroxychloride of the formula Zr(OH)4−bClb wherein b is about 2.8 to about 4.0, preferably about 3.2 to about 4.0, so that the Zr:Cl ratio in said zirconium hydroxychloride is about 0.36 to about 0.25, preferably about 0.31 to about 0.25. The present invention also embraces methods of making such antiperspirant salts and aqueous solutions of such antiperspirant salts. The present invention further embraces topical compositions comprising a dermatologically acceptable carrier and a perspiration reducing effective amount of an aluminum-zirconium antiperspirant salt as described above.

    摘要翻译: 公开了具有约0.9至约1.2,优选约0.9至约1.1,最优选约0.9至约1.0的金属(Al + Zr)与氯化物之比的铝 - 锆氯化水合物止汗剂盐。 为了达到最高的止汗效力,这些盐由式Zr(OH)4-bClb的羟基氯化锆制成,其中b为约2.8至约4.0,优选约3.2至约4.0,使得Zr:Cl 所述羟基氯化锆中的比例为约0.36至约0.25,优选约0.31至约0.25。 本发明还包括制备这种止汗剂盐和这种止汗剂盐的水溶液的方法。 本发明还包括如上所述的包含皮肤病学可接受的载体和减少汗的有效量的铝 - 锆止汗盐的局部组合物。