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    Compositions and methods relating to breast specific genes and proteins
    12.
    发明申请
    Compositions and methods relating to breast specific genes and proteins 审中-公开
    与乳腺特异性基因和蛋白质有关的组成和方法

    公开(公告)号：US20050048559A1

    公开(公告)日：2005-03-03

    申请号：US10958863

    申请日：2004-10-05

    Applicant: Susana Salceda ,  Roberto Macina ,  Herve Recipon ,  Robert Cafferkey ,  Yongming Sun ,  Chenghua Liu

    Inventor： Susana Salceda ,  Roberto Macina ,  Herve Recipon ,  Robert Cafferkey ,  Yongming Sun ,  Chenghua Liu

    IPC: A61K38/00 ,  C07K14/47 ,  C12N15/12 ,  G01N33/574 ,  C12Q1/68 ,  C07H21/04

    CPC classification number: C07K14/47 ,  A61K38/00 ,  G01N33/57415

    Abstract: The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic breast cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating breast cancer and non-cancerous disease states in breast tissue, identifying breast tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered breast tissue for treatment and research.

    Abstract translation: 本发明涉及存在于正常和肿瘤性乳腺细胞中的新鉴定的核酸和多肽，包括核酸和多肽的片段，变体和衍生物。 本发明还涉及本发明多肽的抗体，以及本发明多肽的激动剂和拮抗剂。 本发明还涉及包含本发明的核酸，多肽，抗体，变体，衍生物，激动剂和拮抗剂以及使用这些组合物的方法的组合物。 这些用途包括识别，诊断，监测，分期，成像和治疗乳腺组织中的乳腺癌和非癌性疾病状态，鉴定乳腺组织，监测和鉴定和/或设计本发明多肽的激动剂和拮抗剂。 用途还包括基因治疗，转基因动物和细胞的生产，以及用于治疗和研究的工程乳腺组织的生产。

    UV STERILIZATION CHAMBER FOR A HUMIDIFIER
    15.
    发明申请
    UV STERILIZATION CHAMBER FOR A HUMIDIFIER 审中-公开
    一种除湿器紫外杀菌室

    公开(公告)号：US20130175711A1

    公开(公告)日：2013-07-11

    申请号：US13608875

    申请日：2012-09-10

    Applicant: Francis C. NUTTER ,  Zhijing Wang ,  Robert Zhao ,  Edison Lu ,  Yongming Sun ,  Sean Wang ,  Christopher S. Kanel

    Inventor： Francis C. NUTTER ,  Zhijing Wang ,  Robert Zhao ,  Edison Lu ,  Yongming Sun ,  Sean Wang ,  Christopher S. Kanel

    IPC: F24F13/00 ,  C02F1/32

    CPC classification number: F24F13/00 ,  C02F1/32 ,  F24F6/02 ,  F24F6/043 ,  F24F13/20 ,  F24F2003/1667 ,  F24F2006/006 ,  F24F2006/008

    Abstract: A UV sterilization chamber is provided to a humidifier having a water reservoir, a humidifying element and a pathway for directing water provided by the water reservoir to the humidifying element of the humidifier. The pathway is provided in a humidifier base, over which a humidifier enclosure is removably placed. The UV sterilization chamber includes a serpentine portion of the pathway and a UV radiation source positioned for illuminating the portion of the pathway with UV light. Upwardly-directed projections in the base border a perimeter of the pathway; and a downwardly-directed projection of the UV radiation source extends between the upwardly-directed projections when the enclosure is mated with the base, thereby locating the UV radiation source over the portion of the pathway. A switch disables the UV radiation source when the enclosure is removed from the base.

    Abstract translation: UV加压器设置在具有储水器，加湿元件和用于将由储水器提供的水引导到加湿器的加湿元件的通道的加湿器中。 该通道设置在加湿器基座中，加湿器外壳可移除地放置在该加湿器基座上。 UV消毒室包括路径的蛇形部分和定位成用UV光照射路径部分的UV辐射源。 在基部边界中的向上指向的突起在通路的周边; 并且当外壳与基座配合时，UV辐射源的向下指向的突出部在向上指向的突起之间延伸，从而将UV辐射源定位在路径的该部分上。 当外壳从基座上拆下时，开关会禁用紫外线辐射源。

    Compositions, splice variants and methods relating to ovarian specific genes and proteins
    16.
    发明授权
    Compositions, splice variants and methods relating to ovarian specific genes and proteins 有权

    公开(公告)号：US08460880B2

    公开(公告)日：2013-06-11

    申请号：US12383449

    申请日：2009-03-24

    Applicant: Roberto A. Macina ,  Leah R. Turner ,  Yongming Sun ,  Shu-Hui Liu ,  Huei-Mei Chen

    Inventor： Roberto A. Macina ,  Leah R. Turner ,  Yongming Sun ,  Shu-Hui Liu ,  Huei-Mei Chen

    IPC: G01N33/53

    CPC classification number: C07K14/82 ,  C07K14/47 ,  G01N33/57449

    Abstract: The present invention relates to newly identified nucleic acid molecules and polypeptides present in normal and neoplastic ovarian cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions containing the nucleic acid molecules, polypeptides, antibodies, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating ovarian cancer and non-cancerous disease states in ovarian, identifying ovarian tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered ovarian tissue for treatment and research.

    Compositions and methods relating to breast specific genes and proteins
    20.
    发明授权
    Compositions and methods relating to breast specific genes and proteins 失效
    与乳腺特异性基因和蛋白质有关的组成和方法

    公开(公告)号：US07208267B2

    公开(公告)日：2007-04-24

    申请号：US09989890

    申请日：2001-11-21

    Applicant: Susana Salceda ,  Roberto Macina ,  Herve E. Recipon ,  Jason Pluta ,  Yongming Sun ,  Chenghua Liu

    Inventor： Susana Salceda ,  Roberto Macina ,  Herve E. Recipon ,  Jason Pluta ,  Yongming Sun ,  Chenghua Liu

    IPC: C12Q1/68 ,  C12N15/00 ,  C12N5/00 ,  C12N15/11 ,  C12N15/12 ,  C12P21/02 ,  A61K31/711 ,  A61K31/713

    CPC classification number: C07K14/47 ,  A61K38/00 ,  A61K39/00 ,  A61K2039/505 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/112 ,  C12Q2600/136

    Abstract: The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic breast cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating breast cancer and non-cancerous disease states in breast tissue, identifying breast tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered breast tissue for treatment and research.

    Abstract translation: 本发明涉及存在于正常和肿瘤性乳腺细胞中的新鉴定的核酸和多肽，包括核酸和多肽的片段，变体和衍生物。 本发明还涉及本发明多肽的抗体，以及本发明多肽的激动剂和拮抗剂。 本发明还涉及包含本发明的核酸，多肽，抗体，变体，衍生物，激动剂和拮抗剂以及使用这些组合物的方法的组合物。 这些用途包括识别，诊断，监测，分期，成像和治疗乳腺组织中的乳腺癌和非癌性疾病状态，鉴定乳腺组织，监测和鉴定和/或设计本发明多肽的激动剂和拮抗剂。 用途还包括基因治疗，转基因动物和细胞的生产，以及用于治疗和研究的工程乳腺组织的生产。

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