摘要:
In a fuel interruption device for a fuel tank, a main valve is prevented from opening as a result of the action of an auxiliary valve during closure of the main valve; and more specifically, an auxiliary valve which is caused to move up and down by a float and a main valve which moves up and down in linkage with the up and down movement of the auxiliary valve are accommodated inside a casing which allows the inflow and outflow of liquid fuel and is provided at the end of a passage which connects the fuel tank and canister; a linking projection is provided on one of the valves, that is, either the auxiliary valve or the main valve, so that the main valve moves in linkage with the auxiliary valve in an action that is either advanced or retarded within a predetermined range, and a projection regulating groove into which the linking projection is inserted so that the projection can change its position within the range is formed in the other valve; and auxiliary valve seat and main valve seat open independently in the upper portion of the casing or in the end of the passage.
摘要:
Disclosed is a DNA fragment comprising a base sequence coding for a peptide occurring in human atrium cordis and having diuretic action or a precursor of the peptide, plasmids containing the DNA fragment, microorganisms transformed with the plasmid, and a process for production of the peptide using the transformant.Also disclosed is a new peptide consisting of 126 amino acids occurring in human atrium cordis and a precursor thereof. The peptide has notable diuretic action and hypotensive or antihypertensive actions.
摘要:
An object of the present invention is to provide a hypothermic agent for an animal, a therapeutic agent for hyperthermia in an animal, etc. The present invention provides a hypothermic agent for an animal, a therapeutic agent for hyperthermia in an animal, etc., the agents etc. comprising desacyl ghrelin or its derivative, or a pharmaceutically acceptable salt thereof as an active ingredient.
摘要:
The invention relates to a method of producing optically active 4-chloro-3-hydroxybutanal compound (2) by reacting chloroacetaldehyde with aldehyde compound (1) in the presence of optically active pyrrolidine compound (5). wherein each symbol is as defined in the specification.
摘要:
The invention relates to a method of producing optically active β-aminoaldehyde compound (3) by reacting imine compound (1-1) or sulfone compound (1-2) with aldehyde compound (2) in the presence of an optically active pyrrolidine compound. wherein each symbol is as defined in the specification.
摘要:
A compound represented by the general formula (I): (I) wherein R represents linear, branched, or cyclic alkyl or aryl; a process for producing the compound; and an antitumor agent containing the compound as an active ingredient.
摘要:
The present invention provides a novel peptide having a physiological activity. Because of having a hypotensive activity, this novel peptide is useful in treating a disease caused by hypertension. Also, an antibody to the novel peptide is provided.
摘要:
In order not to nip the clothes or skin of a subject between the joining portions of coil members when a detecting coil for a magnetic resonance diagnostic apparatus is fitted around a region of the subject such as the leg or neck, the detecting coil 100 for a magnetic resonance diagnostic apparatus, which can be separated into an upper coil member 10 and a lower coil member 20 and has an annular shape when these members 10, 20 are integrally joined, is provided at the joining portions of the lower coil member 20 with guards 27, 28 of a silicone rubber having a hardness of Hs80.
摘要:
The present invention provides a method that allows production of stereospecific and asymmetrical five-membered ring-containing compounds serving as synthetic intermediates for formation of five-membered rings of prostaglandins and the like, with high yield and excellent stereoselectivity in terms of diastereoselectivity and enantioselectivity in a short process without requiring troublesome procedures such as optical resolution. The method for producing a five-membered ring-containing compound includes a cyclization step of condensing and cyclizing an α,β-unsaturated nitro compound represented by the following chemical formula (I) with a 1,4-butanedione compound, in the presence of a catalyst formed by a compound having a pyrrolidine ring and an optically active α-carbon relative to the nitrogen on the ring, in a water-insoluble organic solvent and/or a non-oxygen atom-containing water-soluble organic solvent so as to produce the five-membered ring-containing compound represented by the following chemical formula (II).
摘要:
The present invention provides a method that allows production of stereospecific and asymmetrical five-membered ring-containing compounds serving as synthetic intermediates for formation of five-membered rings of prostaglandins and the like, with high yield and excellent stereoselectivity in terms of diastereoselectivity and enantioselectivity in a short process without requiring troublesome procedures such as optical resolution. The method for producing a five-membered ring-containing compound includes a cyclization step of condensing and cyclizing an α,β-unsaturated nitro compound represented by the following chemical formula (I) with a 1,4-butanedione compound, in the presence of a catalyst formed by a compound having a pyrrolidine ring and an optically active α-carbon relative to the nitrogen on the ring, in a water-insoluble organic solvent and/or a non-oxygen atom-containing water-soluble organic solvent so as to produce the five-membered ring-containing compound represented by the following chemical formula (II).