公开(公告)号：US20210309693A1

公开(公告)日：2021-10-07

申请号：US17267666

申请日：2019-06-27

Applicant: AMOREPACIFIC CORPORATION

Inventor： Yong Deog HONG ,  Hyun Woo JEONG

IPC: C07J17/00 ,  A61K8/63 ,  A23L33/105 ,  A61Q19/00 ,  A61K9/00

Abstract: The present specification relates to (20S,24R)-6-O-β-D-glucopyranosyl(1->2)-β-D-glucopyranoside-dammar-3-one-20,24-epoxy-6a,12b,25-triol, which is a novel ginsenoside, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof. The novel ginsenoside exhibits excellent anti-inflammatory effects.

公开(公告)号：US20180312894A1

公开(公告)日：2018-11-01

申请号：US15770019

申请日：2016-10-21

Applicant: AMOREPACIFIC CORPORATION

Inventor： Gi Baeg NAM ,  Dong Hyun KIM ,  Yong Deog HONG ,  Cheng Yi ZHANG ,  Jun Seong PARK

IPC: C12P33/16 ,  C12P33/20 ,  C12N9/42

CPC classification number: C12P33/16 ,  C07H17/00 ,  C07J17/00 ,  C12N9/24 ,  C12N9/2437 ,  C12P19/44 ,  C12P33/20 ,  C12Y302/01004 ,  C12Y302/01015 ,  C12Y302/0104

Abstract: The present invention relates to a method for selectively producing compound K and compound Y, which are originally present in ginseng in a trace amount, from saponins of ginseng, and more specifically to a method capable of obtaining desired target compounds, that is, compound K and compound Y, in high yields, by treating saponins, obtained from ginseng, with particular enzymes to structurally convert the saponins.

公开(公告)号：US20170239159A1

公开(公告)日：2017-08-24

申请号：US15519334

申请日：2014-10-16

Applicant: AMOREPACIFIC CORPORATION

Inventor： Yong Deog HONG ,  Kyum Son KIM ,  Jun Seong PARK ,  Sang Hoon HAN

IPC: A61K8/49 ,  G01N33/50 ,  A61K8/37 ,  A61Q19/00 ,  A61Q19/08

CPC classification number: A61K8/498 ,  A61K8/375 ,  A61K2800/74 ,  A61Q19/00 ,  A61Q19/008 ,  A61Q19/08 ,  G01N33/5023 ,  G01N33/5044 ,  G01N33/80 ,  G01N2800/20

Abstract: The present invention relates to a composition containing a material for regulating the expression of ABH antigens and, more specifically, to a composition capable of: controlling sebum production and alleviating skin trouble by regulating the expression of ABH antigens; preventing skin pore enlargement by providing antioxidant effects; and defending against skin irritation production.

公开(公告)号：US20220218778A1

公开(公告)日：2022-07-14

申请号：US17570765

申请日：2022-01-07

Applicant: AMOREPACIFIC CORPORATION

Inventor： Hyun Woo JEONG ,  Si Young CHO ,  Yong Deog HONG ,  Wanki KIM ,  Miyoung PARK

IPC: A61K36/82 ,  A61K31/352 ,  A61K9/20 ,  A61K9/16 ,  A61K9/00 ,  A61P3/04

Abstract: The present disclosure relates to a composition for reducing body fat, which contains a green tea extract containing 4 wt % or more of gallocatechin gallate based on the total weight of the extract as an active ingredient, and a method for preparing the same. The composition according to the present disclosure provides a superior effect of reducing body fat as the green tea extract containing gallocatechin gallate is contained as an active ingredient. Accordingly, it can provide substances effective for treating obesity through various researches.

公开(公告)号：US20210275621A1

公开(公告)日：2021-09-09

申请号：US17179054

申请日：2021-02-18

Applicant: AMOREPACIFIC CORPORATION

Inventor： Hyungsu KIM ,  Si Young CHO ,  A Young KIM ,  Wonseok PARK ,  Yong Deog HONG

IPC: A61K36/82 ,  A61K31/353 ,  A61P35/00 ,  A61P15/12 ,  A23L33/00 ,  A23L33/105 ,  A23L2/52

Abstract: The present disclosure relates to a method for preventing, alleviating, improving or treating female hormone regulation disorder or symptoms, which contains a green tea extract with contents of ingredients changed. Specifically, the method according to an aspect of the present disclosure includes a step of administering an effective amount of a green tea extract, which contains (−)-gallocatechin gallate (GCG) and (−)-epigallocatechin gallate (EGCG) at specific contents, to a subject in need thereof, and may exhibit an effect of preventing, alleviating, improving or treating female hormone regulation disorder or symptoms.

公开(公告)号：US20210093651A1

公开(公告)日：2021-04-01

申请号：US17031147

申请日：2020-09-24

Applicant: AMOREPACIFIC CORPORATION

Inventor： Yong Deog HONG ,  Hyun Woo JEONG

IPC: A61K31/704 ,  A61K36/258 ,  A61K8/97 ,  A61K8/63 ,  A61P17/00 ,  A61Q19/08

Abstract: The present disclosure relates to a composition comprising (20S,24R)-6-O-β-D-glucopyranosyl(1→2)-β-D-glucopyranoside-dammar-3-one-20,24-epoxy-6a,12b,25-triol, which is a novel ginsenoside, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof as an active ingredient. In addition, it relates to a method for improving skin elasticity or skin wrinkles, which comprises administering an effective amount of (20S,24R)-6-O-β-D-glucopyranosyl(1→2)-β-D-glucopyranoside-dammar-3-one-20,24-epoxy-6a,12b,25-triol, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof to a subject in need thereof. The novel ginsenoside, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof has a superior effect of improving skin elasticity and skin wrinkles.

公开(公告)号：US20200121580A1

公开(公告)日：2020-04-23

申请号：US16656082

申请日：2019-10-17

Applicant: AMOREPACIFIC CORPORATION

Inventor： Yong Deog HONG ,  Hyun Woo JEONG

IPC: A61K8/63 ,  A61Q19/02

Abstract: The present specification relates to a composition containing novel (20S,24R)-6-O-β-D-glucopyranosyl(1→2)-β-D-glucopyranoside-dammar-3-one-20,24-epoxy-6a,12b,25-triol, a pharmaceutically acceptable salt thereof, a hydrate or a solvate thereof as an active ingredient. The composition exhibits an excellent skin brightening effect.

公开(公告)号：US20180320212A1

公开(公告)日：2018-11-08

申请号：US15769995

申请日：2016-10-21

Applicant: AMOREPACIFIC CORPORATION

Inventor： Gi Baeg NAM ,  Dong Hyun KIM ,  Yong Deog HONG ,  Jun Seong PARK

IPC: C12P33/16

CPC classification number: C12P33/16 ,  C07H17/00 ,  C07J17/00 ,  C12P19/44 ,  C12Y302/01004

Abstract: The present invention relates to a method for selectively producing ginsenoside Rd, which is originally present in ginseng in a trace amount, from panaxadiol-type saponins of ginseng, and more specifically to a method capable of obtaining a desired target compound, that is, ginsenoside Rd, in high yields, by treating a panaxadiol-type saponin obtained from ginseng, with particular enzymes to structurally convert the saponins.

公开(公告)号：US20180318198A1

公开(公告)日：2018-11-08

申请号：US15772272

申请日：2016-10-26

Applicant: AMOREPACIFIC CORPORATION

Inventor： Gi Baeg NAM ,  Dong Hyun KIM ,  Yong Deog HONG ,  Cheng Yi ZHANG ,  Jun Seong PARK

IPC: A61K8/63 ,  A61Q17/00 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/08

CPC classification number: A61K8/63 ,  A61K8/60 ,  A61Q17/005 ,  A61Q19/00 ,  A61Q19/007 ,  A61Q19/02 ,  A61Q19/08

Abstract: The present invention relates to a cosmetic composition comprising a compound represented by Formula 1 below as an active ingredient. in the above Formula 1, R1 is -glc(2-1)glc, R2 is -glc, or R1 is -glc, R2 is -glc(6-1)ara(pyr).

公开(公告)号：US20210308166A1

公开(公告)日：2021-10-07

申请号：US17266567

申请日：2019-07-02

Applicant: AMOREPACIFIC CORPORATION

Inventor： Yong Deog HONG ,  Hyun Woo JEONG

IPC: A61K31/7048 ,  A61K36/258 ,  A61K31/7016 ,  A61K8/9789 ,  A23L33/105 ,  A61P39/06 ,  A61Q19/00

Abstract: The present specification relates to a composition comprising (20S,24R)-6-O-β-D-glucopyranosyl(1->2)-β-D-glucopyranoside-dammar-3-one-20,24-epoxy-6a,12b,25-triol, which is a novel ginsenoside, and pharmaceutically acceptable salts thereof, a hydrate thereof or a solvate thereof as an active ingredient. The composition exhibits an excellent antioxidant effect.