公开(公告)号：US10925998B2

公开(公告)日：2021-02-23

申请号：US15959894

申请日：2018-04-23

Applicant: Boston Scientific Scimed, Inc.

Inventor： Joseph Thomas Delaney, Jr. ,  Patrick Willoughby ,  David Robert Wulfman ,  Andrew J. Ro ,  Niraj Gurung

IPC: C08J3/24 ,  C08J7/04 ,  C08J7/056 ,  C08L23/18 ,  C08L23/22 ,  D01D5/08 ,  D01D5/18 ,  D02G3/36 ,  A61L27/16 ,  C08L53/00 ,  A61L27/48 ,  D01D5/00 ,  D01D5/098

Abstract: Aspects herein relate to biocompatible polyisobutylene-fiber composite materials and related methods. In one aspect a biocompatible composite material is included. The biocompatible composite material can include a network of fibers comprising one or more polymers to form a substrate and a continuous, interpenetrating polyisobutylene matrix that is non-porous and completely surrounds the electrospun fibers. Other aspects are included herein.

公开(公告)号：US10426609B2

公开(公告)日：2019-10-01

申请号：US15082239

申请日：2016-03-28

Applicant: Boston Scientific SciMed, Inc.

Inventor： Peter G. Edelman ,  Joseph Thomas Delaney, Jr.

IPC: A61F2/24 ,  A61L27/50 ,  B29C70/30 ,  A61L27/48 ,  B29L31/00

Abstract: A prosthetic heart valve includes a composite material that has a first plurality of fibers embedded in a polymer matrix. Each fiber can have a first extending direction and a plurality of undulations.

公开(公告)号：US10413403B2

公开(公告)日：2019-09-17

申请号：US15205098

申请日：2016-07-08

Applicant: Boston Scientific SciMed, Inc.

Inventor： Mark W. Boden ,  Peter G. Edelman ,  Joseph Thomas Delaney, Jr.

IPC: A61F2/24 ,  A61L27/20

Abstract: A prosthetic heart valve leaflet is composed of a self-reinforced composite (SRC) structure that includes a first layer. The first layer can include a first plurality of fused fibers composed of a first polymeric material in which each fiber is fused to at least one adjacent fiber by a reflowed fiber domain region.

公开(公告)号：US10314696B2

公开(公告)日：2019-06-11

申请号：US15082382

申请日：2016-03-28

Applicant: Boston Scientific SciMed, Inc.

Inventor： David Robert Wulfman ,  Thomas A. Wrobel ,  Crystal Marie Anderson-Cunanan ,  Joseph Thomas Delaney, Jr. ,  Patrick Willoughby ,  Mark W. Boden ,  Peter G. Edelman ,  Michael Eppihimer

IPC: A61F2/24 ,  A61L27/16 ,  A61L27/18 ,  A61L27/52 ,  A61L27/34

Abstract: A prosthetic heart valve leaflet includes a plurality of electrospun fibers at least partially embedded in a polymer matrix. The plurality of fibers includes a first polyisobutylene urethane copolymer having a first predetermined weight average percentage of hard segment portions and the polymer matrix includes a second polyisobutylene urethane copolymer having a second predetermined weight average percentage of the hard segment portions, wherein the first predetermined weight average percentage of the hard segment portions is greater than the second predetermined weight average percentage of the hard segment portions.

公开(公告)号：US09839725B2

公开(公告)日：2017-12-12

申请号：US14820342

申请日：2015-08-06

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Joseph Thomas Delaney, Jr. ,  Kasyap Seethamraju ,  Paul Vincent Grosso

IPC: A61F2/00 ,  C08L75/00 ,  B05D3/00 ,  C08F2/50 ,  A61L31/10 ,  A61L29/08 ,  A61L31/08 ,  A61L31/14 ,  C09D175/04

CPC classification number: A61L31/10 ,  A61L29/085 ,  A61L31/082 ,  A61L31/14 ,  A61L2400/10 ,  A61L2420/02 ,  A61L2420/06 ,  C09D175/04

Abstract: A lubricious coating for use on an implantable medical device includes a heterochelic component, a homotelechelic polymer and biocompatible initiator. Methods of forming such lubricious coatings are also provided.