Abstract:
Systems, methods, and devices for treating cancer can produce field potentials of between 20 mV and 70 mV. In some cases, systems, methods, and devices provided herein can include a plurality of particles. The particles can include at least a first material and at least a second material, which can have electrode potentials configured to form a galvanic couple in the location of cancerous tissue to form a field potential adapted to preferentially target cancerous tissue over healthy tissue.
Abstract:
A stent delivery catheter comprising at least one catheter shaft, the catheter shaft having an inner surface and an outer surface and a distal end and a proximal end, the catheter shaft defining a guidewire lumen, the guidewire lumen comprising a diameter defined by the inner surface of the catheter shaft, a stent disposed within the distal end of the catheter shaft and in contact with the inner surface of the catheter shaft, and a stylet disposed within the distal end of the catheter shaft, the stylet comprising a wave geometry.
Abstract:
Systems for nerve and tissue modulation are disclosed. An illustrative system may include an intravascular nerve modulation system including a catheter shaft, an expandable basket and one or more electrode assemblies affixed to the expandable basket. The one or more electrode assemblies may be affixed to the expandable basket using one or more covers or coatings.
Abstract:
A clip for reducing a dimension of an opening in tissue may include a continuous member having a plurality of legs and a plurality of preformed bends connecting adjacent legs, wherein the plurality of legs form: a first group having two protrusions; a second group having two protrusions; and a third group having two protrusions, wherein each protrusion of each group includes two legs of the continuous member and a corresponding preformed bend connecting the two legs, and each protrusion of each group extends from a region adjacent a first end of the clip to a region adjacent a second end of the clip.
Abstract:
A sensor device for sensing endoluminal geometry may include an expandable element disposed on the distal region of a shaft. The expandable element may be configured to move a collapsed configuration and an expanded configuration. The expandable element may include one or more sensor elements configured to sense proximity of the sensor element to tissue. The sensor device may include an indicator configured to distinguish between contact of the sensor element with tissue, loss of contact and proximity of the sensor element to tissue.
Abstract:
A medical balloon comprising a balloon wall formed from a polymeric material, the balloon wall having an inner surface and an outer surface, the balloon wall comprising patterned recesses in the outer surface thereof and flexible circuits disposed within the patterned recesses, the flexible circuits are defined by an outer perimeter, and devices and methods for making the same.
Abstract:
Medical devices and methods for making and using the same are disclosed. An example medical device may include a medical device for ablation procedures. The medical device may include an elongate shaft having a distal region. An expandable member may be coupled to the distal region. One or more active electrode assemblies may be coupled to the expandable member. The one or more of the active electrode assemblies may include a resistive element adjacent the expandable member. The electrode assembly may include or may be used with microheaters.
Abstract:
A clip for reducing a dimension of an opening in tissue may include a continuous member having a plurality of legs and a plurality of preformed bends connecting adjacent legs, wherein the plurality of legs form: a first group having two protrusions; a second group having two protrusions; and a third group having two protrusions, wherein each protrusion of each group includes two legs of the continuous member and a corresponding preformed bend connecting the two legs, and each protrusion of each group extends from a region adjacent a first end of the clip to a region adjacent a second end of the clip.
Abstract:
Systems for nerve and tissue modulation are disclosed. An illustrative system may include an intravascular nerve modulation system including a catheter shaft, an expandable basket and one or more electrode assemblies affixed to the expandable basket. The one or more electrode assemblies may be affixed to the expandable basket using one or more covers or coatings.
Abstract:
A catheter including an elongated shaft having a distal end and a proximal end, where the catheter includes a thermal element at the distal end thereof. The thermal element may be used in an ablation procedure or other procedure to heat a tissue adjacent a vessel. In some instances, the thermal element may be positioned in a first vessel and may operate to heat tissue adjacent a second vessel or adjacent an ostium between the first vessel and the second vessel. Further, the catheter may include an expandable portion on which the thermal element may be connected or positioned. The expandable portion(s) may comprise a basket or cage, a balloon, a memory shape and formable portion, and/or other mechanical expanders.