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公开(公告)号：US10433955B2
公开(公告)日：2019-10-08
申请号：US15797394
申请日：2017-10-30
Applicant: Boston Scientific Scimed, Inc.
Inventor： Peter G. Edelman , Scott Fisher , Huisun Wang , Richard Charles Gunderson , Horng-Ban Lin , Jeffrey S. Lindquist
IPC: A61F2/24 , B05D1/02 , A61L27/18 , A61L27/34 , B05D7/22 , B05B7/04 , B05B12/00 , B05B13/02 , B05B13/06 , B05B12/14 , B33Y80/00
Abstract: A prosthetic heart valve includes a base and a plurality of polymeric leaflets. Each leaflet has a root portion coupled to the base, and each leaflet has an edge portion substantially opposite the root portion and movable relative to the root portion to coapt with a respective edge portion of at least one of the other leaflets of the plurality of leaflets. Each leaflet includes) at least two polymers along at least one portion of the leaflet, and each leaflet has a composition gradient of each of the at least two polymers along at least one portion of the leaflet.
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公开(公告)号：US10299915B2
公开(公告)日：2019-05-28
申请号：US15082293
申请日：2016-03-28
Applicant: Boston Scientific SciMed, Inc.
Inventor： Peter G. Edelman , Mark W. Boden , Joseph Thomas Delaney, Jr.
Abstract: A prosthetic heart valve includes a plurality of synthetic polymeric leaflets. Each leaflet has a base polymer and a polymer coating at least partially disposed over the base polymer, wherein the polymer coating includes polymerized units of a monomer comprising a zwitterionic group when the polymer coating is exposed to an aqueous environment at a pH of about 7.4.
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公开(公告)号：US10219792B2
公开(公告)日：2019-03-05
申请号：US14720105
申请日：2015-05-22
Applicant: Boston Scientific Scimed, Inc.
Inventor： Peter G. Edelman , Laura Elizabeth Christakis , Colby Harris , Paul E. Zarembo
Abstract: The present disclosure is directed to a delivery catheter with a mechanism of discharging an adhesive during and/or immediately prior to deployment of the medical device by the delivery catheter.
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公开(公告)号：US20180049869A1
公开(公告)日：2018-02-22
申请号：US15797394
申请日：2017-10-30
Applicant: Boston Scientific Scimed, Inc.
Inventor： Peter G. Edelman , Scott Fisher , Huisun Wang , Richard Charles Gunderson , Horng-Ban Lin , Jeffrey S. Lindquist
IPC: A61F2/24
CPC classification number: A61F2/2412 , A61F2/24 , A61F2/2415 , A61F2/2418 , A61F2210/0076 , A61F2250/0014 , A61F2250/0018 , A61F2250/0028 , A61F2250/0036 , A61F2250/0037 , A61L27/18 , A61L27/34 , A61L2430/20 , B05B7/0408 , B05B7/0416 , B05B7/0433 , B05B7/0466 , B05B12/00 , B05B12/1454 , B05B13/0207 , B05B13/0627 , B05D1/02 , B05D7/222 , B05D2254/02 , B33Y80/00 , Y10T29/49405 , C08L75/04 , C08L83/04
Abstract: A prosthetic heart valve includes a base and a plurality of polymeric leaflets. Each leaflet has a root portion coupled to the base, and each leaflet has an edge portion substantially opposite the root portion and movable relative to the root portion to coapt with a respective edge portion of at least one of the other leaflets of the plurality of leaflets. Each leaflet includes) at least two polymers along at least one portion of the leaflet, and each leaflet has a composition gradient of each of the at least two polymers along at least one portion of the leaflet.
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公开(公告)号：US20160296325A1
公开(公告)日：2016-10-13
申请号：US15082239
申请日：2016-03-28
Applicant: Boston Scientific SciMed, Inc.
Inventor： Peter G. Edelman , Joseph Thomas Delaney, JR.
CPC classification number: A61F2/2418 , A61F2/2409 , A61F2/2412 , A61F2/2415 , A61F2210/0071 , A61F2210/0076 , A61F2250/0018 , A61F2250/0028 , A61L27/48 , A61L27/50 , A61L27/507 , B29C70/30 , B29K2995/0046 , B29L2031/7532
Abstract: A prosthetic heart valve includes a composite material that has a first plurality of fibers embedded in a polymer matrix. Each fiber can have a first extending direction and a plurality of undulations.
Abstract translation: 假体心脏瓣膜包括具有嵌入聚合物基质中的第一多个纤维的复合材料。 每个纤维可以具有第一延伸方向和多个起伏。
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Patent Agency Ranking
公开(公告)号：US20150182332A1
公开(公告)日：2015-07-02
申请号：US14656044
申请日：2015-03-12
Applicant: Boston Scientific SciMed, Inc.
Inventor： Peter G. Edelman , Horng-Ban Lin , Scott Fisher , Jeffrey S. Lindquist , Huisun Wang , Richard C. Gunderson
IPC: A61F2/24
CPC classification number: A61F2/2412 , A61F2/24 , A61F2/2415 , A61F2/2418 , A61F2210/0076 , A61F2250/0014 , A61F2250/0018 , A61F2250/0028 , A61F2250/0036 , A61F2250/0037 , A61L27/18 , A61L27/34 , A61L2430/20 , B05B7/0408 , B05B7/0416 , B05B7/0433 , B05B7/0466 , B05B12/00 , B05B12/1454 , B05B13/0207 , B05B13/0627 , B05D1/02 , B05D7/222 , B05D2254/02 , B33Y80/00 , Y10T29/49405 , C08L75/04 , C08L83/04
Abstract: A prosthetic heart valve includes a base and a plurality of polymeric leaflets. Each leaflet has a root portion coupled to the base, and each leaflet has an edge portion substantially opposite the root portion and movable relative to the root portion to coapt with a respective edge portion of at least one of the other leaflets of the plurality of leaflets. Each leaflet includes) at least two polymers along at least one portion of the leaflet, and each leaflet has a composition gradient of each of the at least two polymers along at least one portion of the leaflet.
Abstract translation: 假体心脏瓣膜包括基部和多个聚合单张。 每个小叶具有连接到基部的根部分，并且每个小叶具有基本上与根部相对的边缘部分，并且相对于根部部分可移动以与多个传单中的至少一个其他传单中的至少一个的相应边缘部分配合 。 每个小叶包括）沿着小叶的至少一部分的至少两种聚合物，并且每个小叶具有沿着小叶的至少一部分的每种至少两种聚合物的组成梯度。
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公开(公告)号：US11304798B2
公开(公告)日：2022-04-19
申请号：US16413104
申请日：2019-05-15
Applicant: Boston Scientific Scimed, Inc.
Inventor： David Robert Wulfman , Thomas A. Wrobel , Crystal Marie Anderson-Cunanan , Joseph Thomas Delaney, Jr. , Patrick Willoughby , Mark W. Boden , Peter G. Edelman , Michael Eppihimer
Abstract: A prosthetic heart valve leaflet includes a plurality of electrospun fibers at least partially embedded in a polymer matrix. The plurality of fibers includes a first polyisobutylene urethane copolymer having a first predetermined weight average percentage of hard segment portions and the polymer matrix includes a second polyisobutylene urethane copolymer having a second predetermined weight average percentage of the hard segment portions, wherein the first predetermined weight average percentage of the hard segment portions is greater than the second predetermined weight average percentage of the hard segment portions.
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公开(公告)号：US09814572B2
公开(公告)日：2017-11-14
申请号：US14656044
申请日：2015-03-12
Applicant: Boston Scientific SciMed, Inc.
Inventor： Peter G. Edelman , Horng-Ban Lin , Scott Fisher , Jeffrey S. Lindquist , Huisun Wang , Richard C. Gunderson
IPC: A61F2/24 , A61L27/18 , A61L27/34 , B05D7/22 , B05B7/04 , B05B12/00 , B05B13/02 , B05B13/06 , B05B12/14 , B33Y80/00 , B05D1/02
CPC classification number: A61F2/2412 , A61F2/24 , A61F2/2415 , A61F2/2418 , A61F2210/0076 , A61F2250/0014 , A61F2250/0018 , A61F2250/0028 , A61F2250/0036 , A61F2250/0037 , A61L27/18 , A61L27/34 , A61L2430/20 , B05B7/0408 , B05B7/0416 , B05B7/0433 , B05B7/0466 , B05B12/00 , B05B12/1454 , B05B13/0207 , B05B13/0627 , B05D1/02 , B05D7/222 , B05D2254/02 , B33Y80/00 , Y10T29/49405 , C08L75/04 , C08L83/04
Abstract: A prosthetic heart valve includes a base and a plurality of polymeric leaflets. Each leaflet has a root portion coupled to the base, and each leaflet has an edge portion substantially opposite the root portion and movable relative to the root portion to coapt with a respective edge portion of at least one of the other leaflets of the plurality of leaflets. Each leaflet includes) at least two polymers along at least one portion of the leaflet, and each leaflet has a composition gradient of each of the at least two polymers along at least one portion of the leaflet.
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9.发明申请MEDICAL DEVICES HAVING BIOERODABLE LAYERS FOR THE RELEASE OF THERAPEUTIC AGENTS 审中-公开具有生物可降解层的医疗器械用于治疗药物释放公开(公告)号：US20160129165A1
公开(公告)日：2016-05-12
申请号：US14996555
申请日：2016-01-15
Applicant: BOSTON SCIENTIFIC SCIMED, INC.
Inventor： Jeffrey S. Lindquist , Peter G. Edelman
CPC classification number: A61L31/148 , A61F2002/30062 , A61L27/502 , A61L29/141 , A61L31/10 , A61L31/141 , A61L31/16 , A61L33/0052 , A61L2300/204 , A61L2300/604 , A61L2420/08 , C08L67/04
Abstract: According to an aspect of the present invention, medical devices are provided which comprise: (a) a substrate and (b) bioerodable polymeric layer over the substrate that contains (i) one or more biodegradable polymers (ii) one or more therapeutic agents, and (iii) one or more plasticizers.
Abstract translation: 根据本发明的一个方面，提供了医疗装置，其包括：（a）基底和（b）在基底上的生物可蚀塑性聚合物层，其包含（i）一种或多种可生物降解聚合物（ii）一种或多种治疗剂， 和（iii）一种或多种增塑剂。
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公开(公告)号：US10029070B2
公开(公告)日：2018-07-24
申请号：US14609141
申请日：2015-01-29
Applicant: BOSTON SCIENTIFIC SCIMED, INC.
Inventor： Patrick A. Haverkost , Martin R. Willard , Peter G. Edelman , Jonathan S. Stinson , Jacob D. Edick , Joel N. Groff , Anthony F. Tassoni, Jr.
Abstract: An intravascular catheter is disclosed that includes an elongated shaft defined by a wall including at least one port extending through the wall into a lumen. At least one channel may be defined between layers of polymer making up the catheter shaft. The channel extends along at least a portion of the shaft and is in fluid communication with the port. Outer and inner diameters of the catheter may be substantially constant along the length of the catheter.
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