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公开(公告)号：US20100152219A1
公开(公告)日：2010-06-17
申请号：US12712659
申请日：2010-02-25
Applicant: Michael Howard Block , John W. Lee , David Scott , Haixia Wang , Tao Wang , Dingwei Yu , Yongxin Han , John Anthony Josey , Bin Wang
Inventor： Michael Howard Block , John W. Lee , David Scott , Haixia Wang , Tao Wang , Dingwei Yu , Yongxin Han , John Anthony Josey , Bin Wang
IPC: A61K31/506 , C07D403/12
CPC classification number: C07D401/14 , C07D403/12 , C07D403/14 , C07D409/14 , C07D413/14 , C07D417/04 , C07D471/04 , C07D487/04 , C07D495/04
Abstract: Compounds of formula (I): and their use in the inhibition of Trk activity are described.
Abstract translation: 描述式（I）化合物及其在抑制Trk活性中的用途。
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12.发明授权公开(公告)号：US08114989B2
公开(公告)日：2012-02-14
申请号：US12713777
申请日：2010-02-26
IPC: C07D401/04
CPC classification number: C07D401/14
Abstract: This invention relates to novel compounds having the formula (I): and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment for cancer.
Abstract translation: 本发明涉及具有式（I）的新化合物及其药物组合物及其使用方法。 这些新型化合物为癌症提供治疗。
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13.发明申请公开(公告)号：US20100210648A1
公开(公告)日：2010-08-19
申请号：US12713777
申请日：2010-02-26
IPC: A61K31/5377 , C07D401/14 , A61K31/506 , A61P35/00 , A61P35/02 , C07D413/14
CPC classification number: C07D401/14
Abstract: This invention relates to novel compounds having the formula (I): and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment for cancer.
Abstract translation: 本发明涉及具有式（I）的新化合物及其药物组合物及其使用方法。 这些新型化合物为癌症提供治疗。
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公开(公告)号：US20070142413A1
公开(公告)日：2007-06-21
申请号：US10595807
申请日：2004-11-15
Applicant: Michael Block , John Lee , David Scott , Haixia Wang , Tao Wang , Dingwei Yu , Yongxin Han , John Josey , Bin Wang
Inventor： Michael Block , John Lee , David Scott , Haixia Wang , Tao Wang , Dingwei Yu , Yongxin Han , John Josey , Bin Wang
IPC: A61K31/506 , C07D403/14 , C07D413/14
CPC classification number: C07D401/14 , C07D403/12 , C07D403/14 , C07D409/14 , C07D413/14 , C07D417/04 , C07D471/04 , C07D487/04 , C07D495/04
Abstract: Compounds of formula (I): and their use in the inhibition of Trk activity are described.
Abstract translation: 描述式（I）化合物及其在抑制Trk活性中的用途。
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15.发明授权4-(3-aminopyrazole) pyrimidine derivatives for use as tyrosine kinase inhibitors in the treatment of cancer 失效用作酪氨酸激酶抑制剂治疗癌症的4-（3-氨基吡唑）嘧啶衍生物公开(公告)号：US08088784B2
公开(公告)日：2012-01-03
申请号：US12713695
申请日：2010-02-26
Applicant: Xiaomei Feng , Huiping Guan , Ying Kang , Stephanos Ioannidis , Bo Peng , Mei Su , Bin Wang , Tao Wang , Hai-Jun Zhang
Inventor： Xiaomei Feng , Huiping Guan , Ying Kang , Stephanos Ioannidis , Bo Peng , Mei Su , Bin Wang , Tao Wang , Hai-Jun Zhang
IPC: C07D403/14 , A61K31/506
CPC classification number: C07D403/14
Abstract: This invention relates to novel compounds having the formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment for cancer.
Abstract translation: 本发明涉及具有式（I）的新化合物及其药物组合物及其使用方法。 这些新型化合物为癌症提供治疗。
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Patent Agency Ranking
公开(公告)号：US20080139561A1
公开(公告)日：2008-06-12
申请号：US11815140
申请日：2006-02-01
Applicant: Audrey Davies , Michelle Lamb , Paul Lyne , Tao Wang , Dingwei Yu , Peter Mohr , Bin Wang
Inventor： Audrey Davies , Michelle Lamb , Paul Lyne , Tao Wang , Dingwei Yu , Peter Mohr , Bin Wang
IPC: A61K31/4439 , A61P35/00 , C07D401/14 , C07D413/14 , C07D409/14 , A61K31/5377 , C07D401/12
CPC classification number: C07D401/12 , C07D401/04 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14
Abstract: This invention relates to novel compounds having the Formula (I) to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment for cancer.
Abstract translation: 本发明涉及具有式（I）的新化合物及其药物组合物及其使用方法。 这些新型化合物为癌症提供治疗。
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公开(公告)号：US09975967B2
公开(公告)日：2018-05-22
申请号：US13409735
申请日：2012-03-01
Applicant: Charles Michael Buchanan , Michael Eugene Donelson , Elizabeth Guzman-Morales , Peter Borden Mackenzie , Bin Wang
Inventor： Charles Michael Buchanan , Michael Eugene Donelson , Elizabeth Guzman-Morales , Peter Borden Mackenzie , Bin Wang
IPC: G02F1/1335 , C08B3/16 , C08J5/18 , C08L1/14 , G02B1/04 , C08B3/00 , C08B3/06 , C08B3/08 , G02F1/13363
CPC classification number: C08B3/16 , B32B2457/202 , C08B3/00 , C08B3/06 , C08B3/08 , C08J5/18 , C08J2301/14 , C08L1/14 , G02B1/04 , G02F1/13363 , G02F2001/133631 , Y10T428/10 , Y10T428/1036 , Y10T428/105
Abstract: Regioselectively substituted cellulose esters having a plurality of aryl-acyl substituents and a plurality of alkyl-acyl substituents are disclosed along with methods for making the same. Such cellulose esters may be suitable for use in optical films, such as optical films having certain Nz values, −A optical films, and/or +C optical films. Optical films prepared employing such cellulose esters have a variety of commercial applications, such as, for example, as compensation films in liquid crystal displays and/or waveplates in creating circular polarized light used in 3-D technology.
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公开(公告)号：US09956340B2
公开(公告)日：2018-05-01
申请号：US14307063
申请日：2014-06-17
Applicant: Bin Wang , Jason Shih , Gregory Harbers , Fukang Jiang , Sean Caffey
Inventor： Bin Wang , Jason Shih , Gregory Harbers , Fukang Jiang , Sean Caffey
CPC classification number: A61M5/155 , A61L31/048 , A61L31/14 , A61M5/14212 , A61M5/14276 , A61M5/14593 , A61M31/002 , A61M2005/14204
Abstract: An implantable device has an outer shell that includes an aperture through the housing of the device and, spanning the aperture, a membrane structure permeable to gas but not to liquid. In this way, excess gas may be vented from the device. The membrane and aperture are designed to discourage or even prevent tissue ingrowth.
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公开(公告)号：US09917874B2
公开(公告)日：2018-03-13
申请号：US12887483
申请日：2010-09-21
Applicant: Michael G. Luby , Mark Watson , Payam Pakzad , Bin Wang
Inventor： Michael G. Luby , Mark Watson , Lorenzo Vicisano , Payam Pakzad , Bin Wang
IPC: G06F15/16 , H04L29/06 , H04N21/231 , H04N21/234 , H04N21/2343 , H04N21/235 , H04N21/258 , H04N21/2662 , H04N21/435 , H04N21/44 , H04N21/4402 , H04N21/442 , H04N21/84 , H04N21/845 , H04N21/24
CPC classification number: H04L65/604 , H04L65/4084 , H04L65/602 , H04L65/607 , H04L65/80 , H04N21/23106 , H04N21/23406 , H04N21/234327 , H04N21/235 , H04N21/2401 , H04N21/25808 , H04N21/2662 , H04N21/435 , H04N21/44004 , H04N21/440227 , H04N21/44209 , H04N21/84 , H04N21/8456
Abstract: A block-request streaming system provides for improvements in the user experience and bandwidth efficiency of such systems, typically using an ingestion system that generates data in a form to be served by a conventional file server (HTTP, FTP, or the like), wherein the ingestion system intakes content and prepares it as files or data elements to be served by the file server. A client device can be adapted to take advantage of the ingestion process. The client device might be configured to optimize use of resources, given the information available to it from the ingestion system. This may include configurations to determine the sequence, timing and construction of block requests based on monitoring buffer size and rate of change of buffer size, use of variable sized requests, mapping of block requests to underlying transport connections, flexible pipelining of requests, and/or use of whole file requests based on statistical considerations.
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