公开(公告)号：US20070014573A1

公开(公告)日：2007-01-18

申请号：US10570181

申请日：2003-09-01

Applicant: Xueqin Wei ,  Bing Zhu ,  Zhifeng Wang

Inventor： Xueqin Wei ,  Bing Zhu ,  Zhifeng Wang

IPC: H04B10/20

CPC classification number: H04B10/271 ,  H04B10/27 ,  H04B10/275

Abstract: The invention discloses an interconnection structure and a method for configuring path between the optical networks. The optical network includes a first network and a second network, the first network and the second network each has a number of nodes, a first node of the first network connects with a third node of the second network, a second node of the first network connects with a fourth node of the second network. The method comprises the steps of: setting-up a first path between one of the first node and the second node and another node of the first network; and at least by one link of the link between the first node and the third node and that between the second node and the fourth node, and by the first path, said another node of the first network communicates for path with another node of the second network. By the dual-node interconnection structure and the path configuration shceme of this invention between a ring network and a mesh network, and between mesh networks, the respective advantages of the ring network and the mesh metwork in regard to protection and restoration can be combined effectively, and the existing internetworking schemes between the rings are also compatible.

Abstract translation: 本发明公开了一种用于配置光网络之间的路由的互连结构和方法。 光网络包括第一网络和第二网络，第一网络和第二网络各自具有多个节点，第一网络的第一节点与第二网络的第三节点连接，第一网络的第二节点 与第二网络的第四节点连接。 该方法包括以下步骤：在第一节点和第二节点之一以及第一网络的另一个节点之间建立第一路径; 以及所述第一节点和所述第三节点之间的链路以及所述第二节点和所述第四节点之间的链路的至少一个链路，并且通过所述第一路径，所述第一网络的所述另一个节点与所述第二节点的另一个节点进行通信 网络。 通过环形网络和网状网络之间以及网状网络之间的本发明的双节点互连结构和路径配置，可以有效地组合环网和网状网络在保护和恢复方面的各自优点 ，并且环之间的现有互联方案也是兼容的。

公开(公告)号：US20060277509A1

公开(公告)日：2006-12-07

申请号：US11422314

申请日：2006-06-05

Applicant: Tung-sun Tung ,  Tsair-Chin Lin ,  Bing Zhu

Inventor： Tung-sun Tung ,  Tsair-Chin Lin ,  Bing Zhu

IPC: G06F17/50

CPC classification number: G06F17/5022 ,  G06F17/5027 ,  G06F2217/78

Abstract: The invention described here is the methods of using a hardware-based functional verification system to mimic a design under test (DUT), under intended application environment and software, to record or derive the transition activities of all circuits of the DUT, then calculate the total or partial power consumption during the period of interest. The period of interest is defined by the user in terms of “events” which are the arbitrary states of the DUT. Furthermore, the user can specify the number of sub-divisions required between events thus vary the apparent resolution of the power consumption profile.

Abstract translation: 这里描述的发明是使用基于硬件的功能验证系统在预期的应用环境和软件下模拟被测设计（DUT）来记录或导出DUT的所有电路的转换活动的方法，然后计算 在兴趣期间的全部或部分功耗。 感兴趣的时期由用户根据DUT的任意状态的“事件”定义。 此外，用户可以指定事件之间所需的子分割的数量，从而改变功耗简档的视在分辨率。

公开(公告)号：US09961142B2

公开(公告)日：2018-05-01

申请号：US13818360

申请日：2012-02-15

Applicant: Hui Li ,  Xianxia Huang ,  Hanxu Hou ,  Tai Zhou ,  Bing Zhu ,  Changmin Chen ,  Jingbang Zhou

Inventor： Hui Li ,  Xianxia Huang ,  Hanxu Hou ,  Tai Zhou ,  Bing Zhu ,  Changmin Chen ,  Jingbang Zhou

IPC: H04L29/08 ,  H03M13/15 ,  H03M13/03 ,  G06F11/10

CPC classification number: H04L67/1097 ,  G06F11/1092 ,  H03M13/033 ,  H03M13/1515 ,  H04L67/1095

Abstract: A method, device and system disclosed used in storage technique, comprising: splitting a file of size M into k blocks, that is to say, each block is of size M/k; issuing the above k blocks across k different storage nodes in the distributed network storage system in a distributed manner; using the k blocks, constructing n−k independent blocks via linear coding method, and satisfying the property that any k of the n encoded blocks can be used to reconstruct the original data in the file, which means the linear coding method is a kind of Maximum-Distance Separable (MDS) code; distribute the n−k encoded blocks to the rest n−k different storage codes in the distributed network storage systems.

公开(公告)号：US20140342994A1

公开(公告)日：2014-11-20

申请号：US14344289

申请日：2011-09-16

Applicant: Shifang Yang ,  Junsheng Cui ,  Bing Zhu ,  Peng Wei

Inventor： Shifang Yang ,  Junsheng Cui ,  Bing Zhu ,  Peng Wei

IPC: A61K38/17 ,  A61K45/06 ,  C07K14/47

CPC classification number: A61K38/1761 ,  A61K38/00 ,  A61K45/06 ,  C07K14/47 ,  C07K14/4747 ,  C07K14/52 ,  C07K14/525 ,  C07K14/70575 ,  C07K14/7151 ,  C07K2319/21 ,  C07K2319/33 ,  C12N15/62 ,  C12N15/63

Abstract: Provided is a fusion protein comprising circularly permuted form of TRAIL, and the fusion protein contains circularly permuted form of TRAIL and oligopeptides located at the N-terminus and/or C-terminus of the permuted form. The oligopeptides contain a repeating sequence consisting of 3-10 histidines. The components of the circularly permuted form of TRAIL from N-terminus to C-terminus are: (a) amino acids 135-281 of TRAIL, (b) a linker, and (c) amino acids 121-135 of TRAIL or amino acids 114-135 of TRAIL or amino acids 95-135 of TRAIL or any fragments of amino acids 95-135 of TRAIL containing amino acids 121-135 of TRAIL. Also provided is a method for treating cancer by using the fusion protein.

Abstract translation: 提供了包含循环形式的TRAIL的融合蛋白，并且融合蛋白包含位于置换形式的N末端和/或C末端的循环形式的TRAIL和寡肽。 寡肽含有由3-10组氨酸组成的重复序列。 从N末端到C末端的循环形式的TRAIL的组分是：（a）TRAIL的氨基酸135-281，（b）接头，和（c）TRAIL或氨基酸的氨基酸121-135 TRAIL的114-135或TRAIL的氨基酸95-135或含有TRAIL的第121-135位氨基酸的TRAIL的任何氨基酸95-135的片段。 还提供了通过使用融合蛋白治疗癌症的方法。

公开(公告)号：US20140206025A1

公开(公告)日：2014-07-24

申请号：US14240311

申请日：2011-08-30

Applicant: Shifang Yang ,  Junsheng Cui ,  Peng Wei ,  Xiangjun Zheng ,  Bing Zhu

Inventor： Shifang Yang ,  Junsheng Cui ,  Peng Wei ,  Xiangjun Zheng ,  Bing Zhu

IPC: G01N33/50

CPC classification number: G01N33/5091 ,  G01N33/57484 ,  G01N2333/904 ,  G01N2333/91188 ,  G01N2800/52

Abstract: The present invention relates to a method for early evaluation of clinical efficacy of antitumor intervention measure, comprising evaluating the efficacy of the antitumor intervention measure by assaying whether the content of a tumor-damaging biomarker(s) in the blood of a patient having tumor rises as compared to the baseline level before treatment within a time window after the patients receives at least one antitumor intervention measure. In preferable embodiments, the tumor-damaging biomarker(s) is selected from a group consisting of Alanine Aminotransferase (ALT), Aspartate Transaminase (AST), Lactate Dehydrogenase (LDH); said tumor is multiple myeloma; said antitumor intervention measure is the administration of CPT alone or the administration of CPT in combination with thalidomide.

Abstract translation: 本发明涉及一种用于早期评估抗肿瘤干预措施的临床疗效的方法，包括通过测定患有肿瘤的患者的血液中的肿瘤损伤性生物标志物的含量是否上升来评估抗肿瘤干预措施的功效 与患者接受至少一种抗肿瘤干预措施后的时间窗内治疗前的基线水平相比。 在优选的实施方案中，肿瘤破坏性生物标志物选自丙氨酸氨基转移酶（ALT），天冬氨酸转氨酶（AST），乳酸脱氢酶（LDH）; 所述肿瘤是多发性骨髓瘤; 所述抗肿瘤干预措施是单独使用CPT或与沙利度胺组合使用CPT。

公开(公告)号：US08521267B1

公开(公告)日：2013-08-27

申请号：US11771660

申请日：2007-06-29

Applicant: Laleh Jalali ,  Jay Snell ,  Elizabeth Bacon ,  Katie Hoberman ,  Bing Zhu

Inventor： Laleh Jalali ,  Jay Snell ,  Elizabeth Bacon ,  Katie Hoberman ,  Bing Zhu

IPC: A61B5/0472

CPC classification number: A61B5/0472 ,  A61B5/0022 ,  A61B5/0031 ,  A61N1/3622 ,  A61N1/3627 ,  A61N1/36507 ,  A61N1/36585 ,  G06F19/00 ,  G16H40/63

Abstract: A method and system are provided for trending a coronary burden such as an ischemic burden or acute myocardial infarction (AMI) for a patient. Trending provides obtaining cardiac data over a period of time, identifying the onset and the termination of coronary episodes based on a ST segment variation within the cardiac data, recording coronary burden information, and presenting the coronary burden information to a user. The coronary burden information may include the number of coronary episodes occurring over a period of time, the time duration of the coronary episodes, and the maximum ST segment variations for the coronary episodes that occur over a period of time.

Abstract translation: 提供了一种方法和系统，用于对患者的冠状动脉负荷如缺血负担或急性心肌梗塞（AMI）进行趋势。 趋势提供在一段时间内获得心脏数据，基于心脏数据内的ST段变化识别冠状动脉发作的发作和终止，记录冠状动脉负荷信息，以及向使用者呈现冠状动脉负荷信息。 冠状动脉负荷信息可以包括在一段时间内发生的冠状动脉发作次数，冠状动脉发作的持续时间以及在一段时间内发生的冠状动脉发作的最大ST段变化。

公开(公告)号：US08352235B1

公开(公告)日：2013-01-08

申请号：US11966602

申请日：2007-12-28

Applicant: Tsair-Chin Lin ,  Bing Zhu ,  Platon Beletsky

Inventor： Tsair-Chin Lin ,  Bing Zhu ,  Platon Beletsky

IPC: G06G7/54 ,  G06F17/50 ,  G06F9/455

CPC classification number: G06F17/5036 ,  G06F17/5022 ,  G06F2217/78

Abstract: A method for modeling power management in an integrated circuit (IC) includes: specifying a circuit design and a power architecture for the IC, the power architecture including a plurality of power domains for specifying power levels in different portions of the IC; determining an emulation module for the IC by including one or more hardware elements for modeling the power architecture in the emulation module; and using the emulation module to simulate changing power levels in one or more power domains of the IC including a power shutoff in at least one power domain.

Abstract translation: 一种用于对集成电路（IC）中的功率管理进行建模的方法包括：指定IC的电路设计和电源架构，所述电源架构包括用于指定所述IC的不同部分中的功率电平的多个功率域; 通过包括用于对仿真模块中的电力架构进行建模的一个或多个硬件元件来确定IC的仿真模块; 以及使用所述仿真模块来模拟所述IC的一个或多个功率域中的变化功率水平，包括在至少一个功率域中的功率切断。

公开(公告)号：US08108194B2

公开(公告)日：2012-01-31

申请号：US12346004

申请日：2008-12-30

Applicant: Bing Zhu ,  Tsair-Chin Lin ,  Tung-sun Tung ,  Jingbo Gao

Inventor： Bing Zhu ,  Tsair-Chin Lin ,  Tung-sun Tung ,  Jingbo Gao

IPC: G06F17/50 ,  G06F9/455

CPC classification number: G06F17/5027 ,  G06F2217/78

Abstract: A method of analyzing power consumption for a DUT (device under test) that includes an integrated circuit or an electronic system includes: providing emulation data for states of the DUT in one or more time windows; determining operational mode values from the emulation data and a selection of operational modes that characterize circuit behavior in the one or more time windows; dividing each time window into one or more segments based on at least one power criterion; determining power-activity values for the one or more segments; determining power-consumption values for the one or more segments from the power-activity values; using the power-activity values and the power-consumption values to determine relative power activity across the one or more segments and adjusting the one or more segments to target high power activity over operational modes in the one or more time windows; and saving one or more values for power activity of the DUT in a computer-readable medium.

Abstract translation: 一种分析包括集成电路或电子系统的DUT（被测设备）的功耗的方法包括：在一个或多个时间窗口中提供DUT的状态的仿真数据; 从所述仿真数据确定操作模式值，以及表征所述一个或多个时间窗口中的电路行为的操作模式的选择; 基于至少一个功率标准将每个时间窗分成一个或多个片段; 确定所述一个或多个段的功率活动值; 从所述功率活动值确定所述一个或多个片段的功耗值; 使用功率活动值和功率消耗值来确定跨越所述一个或多个段的相对功率活动并且调整所述一个或多个段以在所述一个或多个时间窗中的操作模式为目标高功率活动; 并且在计算机可读介质中保存DUT的功率活动的一个或多个值。

公开(公告)号：US20110245699A1

公开(公告)日：2011-10-06

申请号：US13049805

申请日：2011-03-16

Applicant: Jay Snell ,  Bing Zhu ,  Katie Hoberman ,  Harish Krishnaswamy

Inventor： Jay Snell ,  Bing Zhu ,  Katie Hoberman ,  Harish Krishnaswamy

IPC: A61B5/0452

CPC classification number: A61B5/0452 ,  A61B5/7264

Abstract: Cardiac activity is sensed over a plurality of heart beats defining a beat set. For each beat in the set, it is determined whether the beat is a non-classified beat (e.g., paced beat, a beat outside of a specified heart rate range or a PVC), or a classified beat. For each classified beat, it is determined whether the beat is a non-detect beat, a minor beat or a major beat. Counts of classified beats, non-classified beats, major beats, minor beats, and non-detect beats are maintained. The beat set is declared to be one of a non-classified set, a major set, a minor set or a non-detect set based on the relative counts of classified beats, non-classified beats, major beats, minor beats, and non-detect beats. Over a period of time, counts of beat-set types are maintained and entry into and exit from ST episodes are determined based on these beat-set counts.

Abstract translation: 在定义拍子组的多个心跳上感测到心脏活动。 对于集合中的每个节拍，确定节拍是否是非分类节拍（例如，节奏拍子，指定的心率范围或PVC之外的节拍）或分类节拍。 对于每个分类的节拍，确定节拍是否是非检测节拍，小节奏或主要节拍。 维持分类节拍，非分类节拍，主要节拍，次要节拍和非检测节拍的数量。 基于分类节拍，非分类节拍，主要节拍，次要节拍和非节奏组合的相对计数，节拍组被宣布为非分类组，主要组，未成年组或未检测组之一 检测节拍 在一段时间内，基于这些节拍设置计算确定节拍类型的计数，并且进入和退出ST剧集。

公开(公告)号：US07930017B1

公开(公告)日：2011-04-19

申请号：US11753759

申请日：2007-05-25

Applicant: Eric S. Fain ,  Jay Snell ,  Katie Hoberman ,  Laleh Jalali ,  Bing Zhu ,  Jeffery D. Snell

Inventor： Eric S. Fain ,  Jay Snell ,  Katie Hoberman ,  Laleh Jalali ,  Bing Zhu ,  Jeffery D. Snell

IPC: A61B5/04

CPC classification number: A61B5/0402 ,  A61B5/024 ,  A61B5/02405 ,  A61B5/6846

Abstract: A method and system are provided for trending variation in coronary burden across multiple heart rate ranges. The method and system include obtaining cardiac signals having a segment of interest over a period of time where each cardiac signal has an associated heart rate that falls within at least one heart rate range. Segment variations of the segment of interest are determined and grouped based on the associated heart rates to produce distributions of segment variations that are associated with the heart rate ranges. Trending information is produced by automatically comparing the distributions of segment variations between different heart rate ranges.

Abstract translation: 提供了一种方法和系统，用于跨越多个心率范围的冠状动脉负荷的趋势变化。 所述方法和系统包括在一段时间内获得具有感兴趣区段的心脏信号，其中每个心脏信号具有落入至少一个心率范围内的相关心率。 基于相关的心率来确定和分组感兴趣区段的区段变化，以产生与心率范围相关联的区段变化的分布。 通过自动比较不同心率范围之间的段变化的分布来产生趋势信息。