公开(公告)号：US09933565B2

公开(公告)日：2018-04-03

申请号：US15211728

申请日：2016-07-15

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Steve Swihart ,  Evan Thrush ,  Yochanan Uri ,  Boaz Ran ,  Itay Barak ,  Kevin McDonald

IPC: G02B6/08 ,  G02B5/22 ,  G01N21/64 ,  G02B5/28 ,  G01N27/447

CPC classification number: G02B6/08 ,  G01N21/6454 ,  G01N27/44721 ,  G01N2021/6484 ,  G02B5/22 ,  G02B5/28

Abstract: Devices, systems, methods, and kits for contact imaging are provided. A contact imaging device includes an imaging sensor, a fixed fiber faceplate mechanically coupled to the imaging sensor, and an optical filtering layer mechanically coupled to the fixed fiber faceplate. The optical filtering layer can include an interference filter, an absorptive filter, and/or a removable fiber faceplate. The contact imaging device can be used to image fluorescent samples by filtering out excitation light on the basis of wavelength and/or angle of incidence.

公开(公告)号：US09794454B2

公开(公告)日：2017-10-17

申请号：US14789717

申请日：2015-07-01

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Yochanan Uri ,  Boaz Ran ,  Itay Barak ,  Steven Swihart ,  Evan Thrush

IPC: H04N5/228 ,  H04N5/225

CPC classification number: H04N5/2252 ,  G01N21/76 ,  G01N21/763 ,  G01N2201/0221

Abstract: Provided herein are imaging cassettes for detecting a luminescent and/or radioactive signals. Such cassettes are useful in common biological assays, e.g., immunoassays, nucleotide detection assays, and other affinity assays.

公开(公告)号：US09774804B2

公开(公告)日：2017-09-26

申请号：US14563411

申请日：2014-12-08

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Boaz Ran ,  Steve Swihart ,  Evan Thrush ,  Itay Barak

IPC: H04N5/361 ,  H04N5/365

CPC classification number: H04N5/361 ,  H04N5/365

Abstract: In one application, an imaging device includes an image sensor having an array of pixels, and a mask coupled with the image sensor. The mask is configured to darken a plurality of isolated pixels or groups of pixels interspersed within the array of pixels. The imaging device also includes a processor coupled with the image sensor and configured to receive image data from the image sensor, and determine a dark current fixed pattern noise based on the image data received from the plurality of darkened pixels or groups of pixels.