公开(公告)号：US10295545B2

公开(公告)日：2019-05-21

申请号：US15922082

申请日：2018-03-15

Applicant: Cambridge Enterprise Limited

Inventor： Emma Yates ,  Christopher Dobson ,  Therese Herling ,  Tuomas Knowles

IPC: B01L3/00 ,  G01N33/50 ,  G01N27/447 ,  B01J19/00 ,  G01N33/52 ,  G01N33/68 ,  G01N15/02 ,  G01N1/10 ,  G01N15/00

Abstract: Flow apparatuses comprising a separation channel, a downstream flow separator, a detection zone, an observation zone, and a waste channel. The separation channel has first and second flows in contact and allows lateral movement of components between contacting first and second flows. The downstream flow separator is in communication with the separation channel and diverts a part of the first fluid flow, the second fluid flow, or both, from the separation channel. The detection zone comprises a detection channel downstream of and in communication with the flow separator and configured to receive a plurality of diverted flows from the flow separator and a label channel configured to label the diverted flows from the flow separator. The observation zone is configured to record an analytical signal indicative of the quantity and the electrical properties of the component. The waste channel is at the downstream end of the observation zone.

公开(公告)号：US09952222B2

公开(公告)日：2018-04-24

申请号：US15036455

申请日：2014-11-14

Applicant: CAMBRIDGE ENTERPRISE LIMITED

Inventor： Emma Yates ,  Christopher Dobson ,  Therese Herling ,  Tuomas Knowles

IPC: B01L3/00 ,  G01N33/68 ,  G01N33/50 ,  B01J19/00 ,  G01N33/52 ,  G01N27/447 ,  G01N15/02 ,  G01N1/10 ,  G01N15/00

CPC classification number: G01N33/6845 ,  B01L3/502753 ,  B01L2200/0631 ,  B01L2200/0636 ,  B01L2300/0816 ,  B01L2300/0861 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/0883 ,  B01L2400/0421 ,  G01N15/0266 ,  G01N27/447 ,  G01N33/50 ,  G01N33/52 ,  G01N2015/0038 ,  G01N2015/0288

Abstract: A method for analyzing a component using a fluidic device. The method includes the steps of providing a distribution of the component across contacting first and second fluid flows; diverting a part of the first fluid flow, a part of the second fluid flow, or parts of the first fluid flow and the second fluid flow, wherein the diverted part includes the component; and analyzing the component in the diverted part of the fluid flow. Optionally the component may be labelled prior to the analyzing step. A flow apparatus for use in the method is also provided.

公开(公告)号：US20150285724A1

公开(公告)日：2015-10-08

申请号：US14438145

申请日：2013-10-22

Applicant: CAMBRIDGE ENTERPRISE LIMITED

Inventor： Samuel Cohen ,  Tuomas Knowles ,  Christopher Dobson ,  Luke Rajah ,  Duncan White

IPC: G01N13/00 ,  G01N33/487

CPC classification number: G01N13/00 ,  B01F5/045 ,  B01F5/0647 ,  B01F13/0093 ,  G01N33/487 ,  G01N2013/003

Abstract: A method for determining the diffusion of one or more components, the method includes the steps of (i) providing a component fluid flow having one or more components; (ii) providing a blank fluid flow; (iii) bringing the flow (i) into contact with the flow (ii) in a large cross section channel, thereby to generate two laminar flows; (iv) permitting the laminar flows generated in (iii) to flow from the large cross section channel into a small cross section channel; measuring the lateral diffusion of the one or more components from the component flow into the blank fluid flow in the small cross section channel. Also provided is a diffusion method having the steps of measuring the lateral diffusion of the one or more components from the component flow into the blank fluid flow at a plurality of diffusion times.

Abstract translation: 一种用于确定一种或多种组分的扩散的方法，所述方法包括以下步骤：（i）提供具有一个或多个组分的组分流体流; （ii）提供空白流体流; （iii）使流动（i）在大截面通道中与流体（ii）接触，从而产生两个层流; （iv）允许（iii）中产生的层流从大截面通道流入小横截面通道; 测量所述一个或多个部件从所述部件流向所述小截面通道中的所述空白流体流的侧向扩散。 还提供了一种扩散方法，其具有以下步骤：在多个扩散时间测量一种或多种组分从组分流向空气流体流中的横向扩散。