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公开(公告)号:US20240342317A1
公开(公告)日:2024-10-17
申请号:US18402399
申请日:2024-01-02
Applicant: CHDI Foundation, Inc.
Inventor: Longbin Liu , Matthew Lee , Celia Dominguez , Peter David Johnson , Catherine Jane Greenaway , Kanika Khurana , Matthew Robert Mills , Filippo Rota
IPC: A61K51/04 , C07B59/00 , C07D231/12 , C07D471/04 , C07D487/04 , C07D487/14 , C07D519/00
CPC classification number: A61K51/0459 , A61K51/0455 , A61K51/0463 , C07B59/002 , C07D231/12 , C07D471/04 , C07D487/04 , C07D487/14 , C07D519/00 , C07B2200/05
Abstract: Provided herein are certain compounds and imaging agents useful for detecting a disease or condition associated with protein aggregation, compositions thereof, and methods of their use.
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公开(公告)号:US11918662B2
公开(公告)日:2024-03-05
申请号:US17344582
申请日:2021-06-10
Applicant: CHDI Foundation, Inc.
Inventor: Longbin Liu , Matthew Lee , Celia Dominguez , Peter David Johnson , Catherine Jane Greenaway , Kanika Khurana , Matthew Robert Mills , Filippo Rota
IPC: A61K51/04 , C07B59/00 , C07D231/12 , C07D471/04 , C07D487/04 , C07D487/14 , C07D519/00
CPC classification number: A61K51/0459 , A61K51/0455 , A61K51/0463 , C07B59/002 , C07D231/12 , C07D471/04 , C07D487/04 , C07D487/14 , C07D519/00 , C07B2200/05
Abstract: Provided herein are certain compounds and imaging agents useful for detecting a disease or condition associated with protein aggregation, compositions thereof, and methods of their use.
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公开(公告)号:US20220339302A1
公开(公告)日:2022-10-27
申请号:US17715661
申请日:2022-04-07
Applicant: CHDI Foundation, Inc.
Inventor: Longbin Liu , Celia Dominguez , Jonathan Bard , Christopher John Brown , Xuemei Chen , Daniel Clark-Frew , Matthew Robert Mills , Peter David Johnson , Elise Gadouleau
IPC: A61K51/04 , A61P25/28 , C07D401/14
Abstract: Provided herein are certain isoindolinone compounds and imaging agents useful for detecting a disease or condition associated with protein aggregation, compositions thereof, and methods of their use.
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公开(公告)号:US20210393812A1
公开(公告)日:2021-12-23
申请号:US17344582
申请日:2021-06-10
Applicant: CHDI Foundation, Inc.
Inventor: Longbin Liu , Matthew Lee , Celia Dominguez , Peter David Johnson , Catherine Jane Greenaway , Kanika Khurana , Matthew Robert Mills , Filippo Rota
IPC: A61K51/04 , C07B59/00 , C07D487/04 , C07D487/14 , C07D519/00 , C07D231/12 , C07D471/04
Abstract: Provided herein are certain compounds and imaging agents useful for detecting a disease or condition associated with protein aggregation, compositions thereof, and methods of their use.
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公开(公告)号:US10907197B2
公开(公告)日:2021-02-02
申请号:US15507217
申请日:2015-08-28
Applicant: CHDI Foundation, Inc.
Inventor: Celia Dominguez , John Wityak , Jonathan Bard , Christopher John Brown , Michael Edward Prime , Derek Alexander Weddell , Daryl Simon Walter , Paul Richard Giles , Ian James Wigginton , Malcolm George Taylor , Sébastien René Gabriel Galan , Peter David Johnson , Thomas Martin Krülle , Inaki Morao , Daniel Clark-Frew
IPC: C07D253/08 , C07D401/04 , C07D473/00 , C12Q1/6823 , A61K51/04
Abstract: Provided are imaging agents comprising a compound of Formula (I), or a pharmaceutically acceptable salt thereof, and methods of their use.
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公开(公告)号:US10479802B2
公开(公告)日:2019-11-19
申请号:US15507208
申请日:2015-08-28
Applicant: CHDI Foundation, Inc.
Inventor: Celia Dominguez , Samuel Coe , Jonathan Bard , Peter David Johnson , Michael Edward Prime , Christopher John Brown , Sébastien René Gabriel Galan , Paul Richard Giles , Elise Luciennen Paulette Gadouleau , Thomas Martin Krülle , Daniel Clark-Frew , John Wityak , Alex Kiselyov , Sarah Hayes
IPC: C07D513/04 , C07D413/14 , C07D471/04 , A61K51/04 , C07D413/12 , C07D263/57 , C07D498/04 , C07D405/14 , C07D413/04
Abstract: Provided are imaging agents comprising a compound of Formula (I), or a pharmaceutically acceptable salt thereof, and methods of their use.
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公开(公告)号:US20170283439A1
公开(公告)日:2017-10-05
申请号:US15507203
申请日:2015-08-28
Applicant: CHDI Foundation, Inc.
Inventor: Celia Dominguez , John Wityak , Jonathan Bard , Alex Kiselyov , Christopher John Brown , Michael Edward Prime , Peter David Johnson , Daniel CLark-Frew
IPC: C07D519/00 , A61K51/04 , C07D471/04
CPC classification number: C07D519/00 , A61K51/0455 , A61K51/0459 , C07D471/04
Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
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公开(公告)号:US11992535B2
公开(公告)日:2024-05-28
申请号:US17125905
申请日:2020-12-17
Applicant: CHDI Foundation, Inc.
Inventor: Longbin Liu , Matthew Lee , Celia Dominguez , Peter David Johnson , Christopher John Brown , Sarah Hayes , Adrian Kotey , Matthew Robert Mills , Michael Edward Prime
IPC: A61K51/04 , C07B59/00 , C07D401/06 , C07D401/12 , C07D401/14 , C07D413/14 , C07D471/04 , C07D487/04 , C07D491/107
CPC classification number: A61K51/0455 , A61K51/0459 , A61K51/0468 , C07B59/00 , C07D401/06 , C07D401/12 , C07D401/14 , C07D413/14 , C07D471/04 , C07D487/04 , C07D491/107 , C07B2200/05
Abstract: Provided herein are certain compounds and imaging agents useful for detecting a condition or disorder associated with protein aggregation, compositions thereof, and methods of their use.
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公开(公告)号:US11851446B2
公开(公告)日:2023-12-26
申请号:US17353627
申请日:2021-06-21
Applicant: CHDI Foundation, Inc.
Inventor: Celia Dominguez , John Wityak , Jonathan Bard , Alex Kiselyov , Christopher John Brown , Michael Edward Prime , Peter David Johnson , Daniel Clark-Frew
IPC: C07D519/00 , C07D471/04 , A61K51/04
CPC classification number: C07D519/00 , A61K51/0455 , A61K51/0459 , C07D471/04
Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
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公开(公告)号:US20210380608A1
公开(公告)日:2021-12-09
申请号:US17353627
申请日:2021-06-21
Applicant: CHDI Foundation, Inc.
Inventor: Celia Dominguez , John Wityak , Jonathan Bard , Alex Kiselyov , Christopher John Brown , Michael Edward Prime , Peter David Johnson , Daniel Clark-Frew
IPC: C07D519/00 , C07D471/04 , A61K51/04
Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
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