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11.发明授权公开(公告)号：US08709148B2
公开(公告)日：2014-04-29
申请号：US13131344
申请日：2009-11-24
IPC分类号： C04B14/04
CPC分类号： C09C1/0051 , C01P2004/03 , C01P2004/04 , C01P2004/51 , C03C12/00 , C03C17/23 , C09C1/0015 , C09C1/0018 , C09C1/0021 , C09C1/0024 , C09C1/0039 , C09C1/0057 , C09C1/0066 , C09C2200/301 , C09C2200/502 , C09C2200/505
摘要： Particles colored with at least one colorant, where the colored glass particles are glass platelets with an average diameter of 1 to 500 μm and the colorants at least include at least one of metallic nanoparticles and metal oxides. The glass platelets are planar and the colorants are present in a concentration from 1% to 55% by weight, based on the total weight of the colored glass platelets. The disclosure further relates to a method to a method for producing the colored glass particles and to the use thereof.
摘要翻译： 用至少一种着色剂着色的颗粒，其中着色玻璃颗粒是平均直径为1至500μm的玻璃片，并且着色剂至少包括金属纳米颗粒和金属氧化物中的至少一种。 玻璃片是平面的，并且着色剂以基于有色玻璃片的总重量的1重量％至55重量％的浓度存在。 本发明还涉及一种生产有色玻璃颗粒的方法及其用途。
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公开(公告)号：US20100003317A1
公开(公告)日：2010-01-07
申请号：US12412206
申请日：2009-03-26
申请人： Akin Akinc , Tomoko Nakayama , David Konys , Markus Stoffel , Christian Wolfrum
发明人： Akin Akinc , Tomoko Nakayama , David Konys , Markus Stoffel , Christian Wolfrum
IPC分类号： A61K9/127 , A61K31/7052 , A61P43/00
CPC分类号： A61K47/69 , A61K47/554
摘要： This invention relates to new formulated lipid particles (FLiPs) comprising at least one of a single or double stranded oligonucleotide, where the oligonucleotide has been conjugated to a lipophile and at least one of an emulsion or liposome to which the conjugated oligonucleotide has been aggregated, admixed or associated. These particles have surprisingly been shown to effectively deliver oligonucleotides to heart, lung and muscle where they effect gene silencing.
摘要翻译： 本发明涉及包含单链或双链寡核苷酸中的至少一种的新配制的脂质颗粒（FLiP），其中所述寡核苷酸已经与亲脂体共轭，并且已经聚合了缀合的寡核苷酸的乳剂或脂质体中的至少一种， 混合或相关。 这些颗粒令人惊讶地被证明可以有效地将寡核苷酸递送到心脏，肺和肌肉，在那里它们影响基因沉默。
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公开(公告)号：US06784219B2
公开(公告)日：2004-08-31
申请号：US09482990
申请日：2000-01-15
申请人： Peter Heitkämper , Klaus Jost , Eduard Mayer , Thomas Münzmay , Joachim Wagner , Christian Wolfrum
发明人： Peter Heitkämper , Klaus Jost , Eduard Mayer , Thomas Münzmay , Joachim Wagner , Christian Wolfrum
IPC分类号： C08G1810
CPC分类号： C08G18/7614 , C08G18/10 , C08G18/3206
摘要： The present invention relates to polyurethane cast elastomers which are prepared from higher molecular weight polyhydroxy compounds, durene diisocyanate and low molecular weight chain-lengthening and/or crosslinking agents. These elastomers are particularly useful for the production of moldings exposed to high mechanical stresses.
摘要翻译： 本发明涉及由较高分子量的多羟基化合物，杜烯二异氰酸酯和低分子量链延长和/或交联剂制备的聚氨酯浇铸弹性体。 这些弹性体对于暴露于高机械应力的模制品的生产特别有用。
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14.发明授权Coating method using special powdered coating materials and use of such coating materials 有权使用特殊粉末涂料的涂布方法和使用这种涂料公开(公告)号：US09580787B2
公开(公告)日：2017-02-28
申请号：US14234872
申请日：2012-07-25
CPC分类号： C23C4/08 , C23C4/04 , C23C4/06 , C23C4/067 , C23C4/10 , C23C4/12 , C23C4/123 , C23C4/129 , C23C4/134 , C23C24/04
摘要： The invention relates to the use of a particle-containing powdered coating material in a coating method selected from the group consisting of cold gas spraying, flame spraying, high-speed flame spraying, thermal plasma spraying and non-thermal plasma spraying, wherein the particles have a relative deformability factor Vm of at most 0.1 and the relative deformability factor is defined according to Formula (I): V m = d D 50 , ( I ) wherein d is the average smallest thickness of the particles, measured vertical to and in the middle half of the longitudinal axis of the particles, and D50 is the average diameter of the volume-averaged particle-size distribution. The invention furthermore relates to a method for coating.
摘要翻译： 本发明还涉及一种涂覆方法。
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15.发明申请Methods for Substrate Coating and Use of Additive-Containing Powdered Coating Materials in Such Methods 审中-公开在这种方法中基质涂层和添加剂粉末涂料的使用方法公开(公告)号：US20140230692A1
公开(公告)日：2014-08-21
申请号：US14234851
申请日：2012-07-25
摘要： The present invention relates to the use of a particle-containing powdered coating material, wherein an additive has been at least partially applied to the surface of the particles, in coating methods, in particular in cold gas spraying, flame spraying, high-speed flame spraying, thermal plasma spraying and non-thermal plasma spraying. Furthermore, the present invention relates to coating methods, in particular the above-named methods, using the powdered coating material according to the invention.
摘要翻译： 本发明涉及包覆粉末涂料的用途，其中添加剂至少部分地施加到颗粒的表面，在涂覆方法中，特别是在冷气喷涂，火焰喷涂，高速火焰 喷涂，热等离子喷涂和非等离子喷涂。 此外，本发明涉及使用根据本发明的粉末涂料的涂布方法，特别是上述方法。
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公开(公告)号：US20130112912A1
公开(公告)日：2013-05-09
申请号：US13808964
申请日：2011-07-05
申请人： Christian Wolfrum , Stefan Trummer , Marco Greb
发明人： Christian Wolfrum , Stefan Trummer , Marco Greb
IPC分类号： H01F1/01
CPC分类号： H01F1/01 , C01P2004/20 , C01P2004/54 , C01P2006/42 , C09C1/62 , C10M125/04 , C10M171/00 , C10M171/06 , C10M173/00 , C10M2201/064 , C10M2203/1025 , C10M2205/0285 , C10M2207/2855 , C10M2229/025 , C10N2210/08 , C10N2220/022 , C10N2220/082 , C10N2220/084 , C10N2230/02 , C10N2240/02 , C10N2240/04 , C10N2240/08 , C10N2240/205 , H01F1/447 , Y10T428/2982
摘要： The invention relates to lamina-like iron pigments produced by deformation of carbonyl iron powder, the lamina-like iron pigments having a size distribution with a D50 value in a range of from 3 to 16 μm and a size/thickness ratio in a range of from 2 to 50. The invention furthermore relates to a magnetorheological fluid which contains the lamina-like iron pigments according to the invention, as well as to a device which contains the magnetorheological fluid.
摘要翻译： 本发明涉及由羰基铁粉的变形产生的层状铁颜料，层状铁颜料的D50值在3〜16μm的范围内，尺寸/厚度比在 本发明还涉及一种含有根据本发明的层状铁颜料的磁流变流体，以及包含磁流变流体的装置。
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公开(公告)号：US08318860B1
公开(公告)日：2012-11-27
申请号：US12679274
申请日：2008-09-17
申请人： Christian Wolfrum , Wolfgang Prinz
发明人： Christian Wolfrum , Wolfgang Prinz
IPC分类号： C08L71/02
摘要： The invention relates to a method for the fluid-phase synthesis of a polymer formed from n monomers.
摘要翻译： 本发明涉及由n种单体形成的聚合物的流相合成方法。
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18.发明申请METHOD AND DEVICE FOR AUTHENTICATING OBJECTS PROVIDED WITH A MARKER, THE SPECIFICATION OF WHICH: 审中-公开用于认证提供标记的对象的方法和设备，其规格如下：公开(公告)号：US20110300640A1
公开(公告)日：2011-12-08
申请号：US12307107
申请日：2007-07-03
申请人： Andre Josten , Christian Wolfrum
发明人： Andre Josten , Christian Wolfrum
CPC分类号： C12Q1/68 , C12Q2563/185 , C12Q2563/179 , C12Q2565/1015 , C12Q2545/101
摘要： The invention relates to a method for authenticating objects provided with a marker that contains nucleic acid.
摘要翻译： 本发明涉及一种用于认证具有含有核酸的标记物的物体的方法。
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19.发明申请公开(公告)号：US20070166710A1
公开(公告)日：2007-07-19
申请号：US10551392
申请日：2004-03-31
CPC分类号： C12Q1/6897 , A61K38/1709 , A61K48/00 , C12Q1/485 , G01N33/5044 , G01N2333/47 , G01N2500/10 , G01N2800/044
摘要： The present invention relates to methods for inhibiting adieogenesis and methods for treating obesity, metabolic syndrome and non-insulin dependent diabetes mellitus by administering an agent that increases Foxa-2 or Fxr, or an agent that activates Fxr. The invention is further related to methods for identifying agents that increase Foxa-2 or Fxr, or activate Fxr, and the use of such agents for treatment of obesity, metabolic syndrome and non-insulin dependent diabetes mellitus. Methods of identifying agents that mediate the phosphorylation of the transcription factor Foxa-2 are provided. Such agents are useful in methods of treating Type 2 diabetes.
摘要翻译： 本发明涉及通过施用增加Foxa-2或Fxr的药剂或活化Fxr的药剂来抑制增殖的方法和治疗肥胖症，代谢综合征和非胰岛素依赖性糖尿病的方法。 本发明进一步涉及用于鉴定增加Foxa-2或Fxr或激活Fxr的药剂的方法，以及用于治疗肥胖症，代谢综合征和非胰岛素依赖性糖尿病的药物的用途。 提供介导介导转录因子Foxa-2磷酸化的试剂的方法。 这些药物可用于治疗2型糖尿病的方法。
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