公开(公告)号：US20230190466A1

公开(公告)日：2023-06-22

申请号：US18113552

申请日：2023-02-23

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Michael R. Bialas ,  Kristen Hicks ,  Michael C. Murad ,  Gil Senesh ,  Quang Ngoc Vu ,  Gonzalo German Angelico ,  Carla Susana Cerqueira ,  Victoria Mariko Low ,  Andrea Fernandez ,  Karl J. Britzman ,  Shannon Nicole Ash (formerly Hoye) ,  Haley Nicole Whitehead

IPC: A61F2/24

CPC classification number: A61F2/2433 ,  A61F2/2436 ,  A61F2/2418 ,  A61F2250/0098 ,  A61F2002/9583

Abstract: Methods and systems for rotationally aligning a commissure of a prosthetic heart valve with a commissure of a native valve are disclosed. In some examples, a delivery apparatus can include a first shaft configured to rotate around a central longitudinal axis of the delivery apparatus to rotationally align a prosthetic valve mounted on the delivery apparatus with native anatomy, a second shaft extending through the first shaft and having a distal end portion extending distally beyond a distal end portion of the first shaft, an inflatable balloon coupled to the distal end portion of the first shaft, and a distal shoulder mounted on the distal end portion of the second shaft and arranged within a distal end portion of the balloon. The distal shoulder comprises a base portion and a flared portion that extends radially outward from the base portion, and a radiopaque marker is disposed on the flared portion.

公开(公告)号：US12290436B2

公开(公告)日：2025-05-06

申请号：US17316885

申请日：2021-05-11

Applicant: Edwards Lifesciences Corporation

Inventor： Nikolai Gurovich ,  Michael Bukin ,  Elena Sherman ,  Tamir S. Levi ,  Ziv Yohanan ,  Gil Senesh ,  Dikla Kersh ,  Alexey Tsypenyuk ,  Waina Michelle Chu ,  Alexander Barash

IPC: A61F2/24 ,  A61F2/90

Abstract: A prosthetic heart valve can include a radially expandable and compressible frame having an inflow end portion and an outflow end portion, the frame comprising a plurality of struts defining openings between them. The prosthetic valve can further include a valvular structure comprising a plurality of leaflets, each leaflet comprising a main body, opposing tabs on opposite sides of the main body, a coaptation edge portion, and a cusp edge portion. Each tab can be paired with an adjacent tab of an adjacent leaflet to form a plurality of commissures that are fixed relative to the frame, and each leaflet can have opposing edge portions between the opposing tabs and the cusp edge portion that are unattached to the frame, each unattached edge portion defining a gap that extends radially into the main body of the leaflet.

公开(公告)号：US12226312B2

公开(公告)日：2025-02-18

申请号：US18316942

申请日：2023-05-12

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Nikolai Gurovich ,  Michael Bukin ,  Elena Sherman ,  Tamir S. Levi ,  Ziv Yohanan ,  Gil Senesh ,  Dikla Kersh ,  Alexey Tsypenyuk ,  Waina Michelle Chu ,  Alexander Barash

IPC: A61F2/24 ,  A61F2/90

Abstract: A prosthetic heart valve can include a radially expandable and compressible frame having an inflow end, an outflow end, and a plurality of struts. The prosthetic valve can further include a valvular structure comprising a plurality of leaflets, each leaflet comprising a coaptation edge portion and a cusp edge portion. The cusp edge portion of each leaflet can be folded toward the outflow end of the frame along a bending axis and a reinforcing member extends along an outflow surface of the cusp edge portion along the bending axis. The prosthetic heart valve can include a plurality of connecting skirts, each disposed between the cusp edge portion of an adjacent leaflet and the frame. First stitching secures the reinforcing member and the connecting skirts to the cusp edge portions and second stitching secures the connecting skirts to selected struts of the frame.

公开(公告)号：US12004947B1

公开(公告)日：2024-06-11

申请号：US18316056

申请日：2023-05-11

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Jeanette Jasmine Corona ,  Brendan Michael Dalbow ,  Gil Senesh

IPC: A61F2/24

CPC classification number: A61F2/2415 ,  A61F2/2412 ,  A61F2220/0075

Abstract: Methods and assemblies for attaching leaflets to a frame of a prosthetic heart valve using a connecting skirt are disclosed. As one example, a prosthetic heart valve can include an annular frame comprising a plurality of struts and a valvular structure mounted within the frame and comprising a plurality of leaflets. A cusp edge portion of each leaflet can be connected to the frame by a connecting skirt, where each connecting skirt comprises a central portion and opposing side base portions on opposite sides of the central portion that are connected to each of and disposed between the frame and the cusp edge portion of the leaflet and each connecting skirt can further comprise side extension portions that extend outward from the cusp edge portion of the leaflet and across struts of the frame that are disposed between cusp edge portions of two adjacent leaflets.

公开(公告)号：US20240058129A1

公开(公告)日：2024-02-22

申请号：US18112455

申请日：2023-02-21

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Shaun Fetherston ,  Alexander H. Siemons ,  Blake W. Axelrod ,  Gil Senesh ,  Tomer Saar ,  Oren Cohen ,  Elazar Levi Schwarcz ,  Tamir S. Levi ,  Michael Bukin ,  Michael R. Bialas ,  Timothy A. Geiser ,  Sudarsan Pranatharthikaran ,  Carla Susana Cerqueira

IPC: A61F2/24 ,  A61B8/00 ,  A61B8/08

CPC classification number: A61F2/2496 ,  A61B8/445 ,  A61B8/0883 ,  A61F2/2433 ,  A61B2090/064

Abstract: A medical balloon sensing assembly constituted of: a handle; a first catheter extending distally from the handle; an inflatable medical balloon, the inflatable medical balloon secured by the first catheter; at least one sensor position member; and at least one sensor secured to the at least one sensor position member, wherein the at least one sensor position member is arranged to contact an outer face of the inflatable medical balloon.

公开(公告)号：US20230255756A1

公开(公告)日：2023-08-17

申请号：US18114070

申请日：2023-02-24

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Jeanette Jasmine Corona ,  Taylor Michael Winters ,  Ashley Akemi Ishigo ,  Lien Huong Thi Hoang ,  Gil Senesh ,  Vicky Hong Do ,  Quang Ngoc Vu ,  Kim D. Nguyen ,  Brendan Michael Dalbow

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2250/0098 ,  A61F2220/0075

Abstract: Methods and systems for attaching a radiopaque marker to a prosthetic heart valve to indicate a location of a commissure of the prosthetic heart valve are disclosed. As one embodiment, a prosthetic heart valve can include a frame including a plurality of struts forming a plurality of cells of the frame arranged between an inflow end and an outflow end of the frame, a plurality of leaflets arranged within the frame, at least one commissure comprising an attachment member arranged across a selected cell of the plurality of cells of the frame and attached to struts of the frame forming the selected cell, and commissure tabs of two adjacent leaflets coupled to the attachment member, and a radiopaque marker arranged on the attachment member of the commissure. The marker is configured to indicate a location of the commissure of the prosthetic heart valve.

公开(公告)号：US20220241071A1

公开(公告)日：2022-08-04

申请号：US17659577

申请日：2022-04-18

Applicant: Edwards Lifesciences Corporation

Inventor： Nikolay Gurovich ,  Michael Bukin ,  Elena Sherman ,  Tamir S. Levi ,  Ziv Yohanan ,  Gil Senesh ,  Dikla Kersh ,  Alexey Tsypenyuk ,  Waina Michelle Chu ,  Alexander Barash

IPC: A61F2/24

Abstract: A system can include a delivery catheter comprising a balloon and an implantable prosthetic heart valve. The prosthetic valve can have a plastically expandable and compressible unitary frame comprising first, second, and third rows of angled struts that define two circumferentially extending rows of diamond-shaped cells that extend continuously around the frame, and a valvular structure comprising a plurality of leaflets. A cusp edge portion of each leaflet is connected to the frame by a skirt that is connected to and disposed between the frame and the cusp edge portions of the leaflets, the skirt being connected to consecutive struts in the first, second, and third rows of struts with sutures. The compressed prosthetic heart valve can be mounted around the balloon and radially expanded to the expanded configuration with the balloon inside a patient's body.

公开(公告)号：US20220241070A1

公开(公告)日：2022-08-04

申请号：US17659169

申请日：2022-04-13

Applicant: Edwards Lifesciences Corporation

Inventor： Nikolay Gurovich ,  Michael Bukin ,  Elena Sherman ,  Tamir S. Levi ,  Ziv Yohanan ,  Gil Senesh ,  Dikla Kersh ,  Alexey Tsypenyuk ,  Waina Michelle Chu ,  Alexander Barash

IPC: A61F2/24

Abstract: A system can include a delivery catheter comprising a balloon and an implantable prosthetic heart valve. The prosthetic valve can have a plastically expandable and compressible unitary frame comprising a plurality of circumferentially extending rows of angled struts, including first, second, and third rows of angled struts forming rows of diamond-shaped cells, and a valvular structure comprising a plurality of leaflets. A cusp edge portion of each leaflet is connected to the frame by a skirt that is disposed between the frame and the cusp edge portions, the skirt being sutured to selected struts of the frame along diagonal paths extending from an inflow end portion toward an outflow end portion. Each diagonal path along which the skirt is sutured to the frame extends along the first, second, and third rows of angled struts.

公开(公告)号：US20200069415A1

公开(公告)日：2020-03-05

申请号：US16551634

申请日：2019-08-26

Applicant: Edwards Lifesciences Corporation

Inventor： Michael R. Bialas ,  Robert James Gerard ,  Gil Senesh

IPC: A61F2/24

Abstract: A method of implanting a prosthetic heart valve includes selecting a prosthetic heart valve. The selected prosthetic heart valve has a nominal diameter that is greater than a native annulus diameter of a native annulus by up to forty percent. The method further comprises compressing the selected prosthetic heart valve to a radially compressed configuration in which the selected prosthetic heart valve has a first diameter that is less than the nominal diameter, positioning the selected prosthetic heart valve within the native annulus, and expanding the selected prosthetic heart valve from the radially compressed configuration to a radially expanded configuration in which the selected prosthetic heart valve has a second diameter which is less than the nominal diameter by up to ten percent and which is greater than the first diameter.

公开(公告)号：US12171655B2

公开(公告)日：2024-12-24

申请号：US18113552

申请日：2023-02-23

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Michael R. Bialas ,  Kristen Hicks ,  Michael C. Murad ,  Gil Senesh ,  Quang Ngoc Vu ,  Gonzalo German Angelico ,  Carla Susana Cerqueira ,  Victoria Mariko Low ,  Andrea Fernandez ,  Karl J. Britzman ,  Shannon Nicole Ash ,  Haley Nicole Whitehead

IPC: A61F2/24 ,  A61B50/30 ,  A61M25/10 ,  A61F2/95 ,  A61F2/958

Abstract: Methods and systems for rotationally aligning a commissure of a prosthetic heart valve with a commissure of a native valve are disclosed. In some examples, a delivery apparatus can include a first shaft configured to rotate around a central longitudinal axis of the delivery apparatus to rotationally align a prosthetic valve mounted on the delivery apparatus with native anatomy, a second shaft extending through the first shaft and having a distal end portion extending distally beyond a distal end portion of the first shaft, an inflatable balloon coupled to the distal end portion of the first shaft, and a distal shoulder mounted on the distal end portion of the second shaft and arranged within a distal end portion of the balloon. The distal shoulder comprises a base portion and a flared portion that extends radially outward from the base portion, and a radiopaque marker is disposed on the flared portion.