摘要:
A device for the propulsion and eccentric braking of a vehicle having a pedal drive, which includes a first shaft, a drive mechanism including one or a plurality of chain wheels, belt pulleys or elements of a Cardan drive, a second hollow shaft arranged concentrically about the first shaft mounted into a rear wheel, a freewheel clutch mounted between the first shaft and the drive mechanism, and an optionally engageable reverse gear mechanism mounted between the first and the second shaft. The first and the second shafts are connected to each other in a torsionally rigid manner when the reverse gear mechanism is in the engaged and disengaged state. The freewheel clutch prevents a rotation of the drive mechanism relative to the first shaft in a clockwise direction and is in a freewheeling state when the drive mechanism rotates in a counter-clockwise direction relative to the first shaft.
摘要:
A device for foaming liquid foods in a container, particularly milk, is provided having a vapor generator for generating vapors, particularly steam, and a vapor lance to be at least partially inserted into the container, with the vapor lance being connected to the vapor generator in a fluid-guiding fashion and including at least one vapor outlet opening such that steam can be discharged from the vapor generator via the vapor lance out of the vapor outlet opening. The device further includes at least one motion element which is connected to the vapor lance and/or a holder for the container such that the vapor lance and the container are movable relative to each other via the motion element.
摘要:
A device for foaming liquid foods in a container, particularly milk, is provided having a vapor generator for generating vapors, particularly steam, and a vapor lance to be at least partially inserted into the container, with the vapor lance being connected to the vapor generator in a fluid-guiding fashion and including at least one vapor outlet opening such that steam can be discharged from the vapor generator via the vapor lance out of the vapor outlet opening. The device further includes at least one motion element which is connected to the vapor lance and/or a holder for the container such that the vapor lance and the container are movable relative to each other via the motion element.
摘要:
A method for obtaining a Staphylococcus carnosus bacterium expressing at its membrane surface a recombinant polypeptide derived from RSV protein G, said polypeptide having a sequence which is a modification of SEQ ID No. 1 and SEQ ID No. 2 (sequence encompassed between residues 130 and 230 of RSV A and RSV B protein G respectively) wherein at least one of position 44 and 57 is serine is disclosed.
摘要:
Preparation of 5-cyanovalerates (I) by the carbonylation of a 1-cyanobutene with carbon monoxide and an alkanol (II) corresponding to the ester radical at an elevated temperature and under superatmospheric pressure in the presence of a cobalt catalyst as well as in the presence of an activating solvent, in which the activating solvent used is an effective amount of a carbonic diester, a carbamate, or a urea of the general formula IIIa, IIIb, or IIIcR--O--CO--O--R (IIIa)R.sub.2 N--CO--O--R (IIIb)R.sub.2 N--CO--NR.sub.2 (IIIc)or a mixture of these compounds (R's same or different, C.sub.1 -C.sub.6 alkyl, C.sub.5 -C.sub.7 cycloalkyl groups or together form 5-membered to 7-membered rings).The end products I serve as intermediates, chiefly for the preparation of .epsilon.-caprolactam.
摘要:
The invention relates to a device (1, 10) for the production of cooled coffee, comprising a brewing unit (4) for the production of coffee, a cooling assembly (11) and a coffee cooler (14) formed as a heat exchanger, wherein the coffee cooler (14) has at least one first and one second flow path that are connected thermally but not in a fluid-conducting manner, wherein a coolant can flow through the first flow path and the second flow path is connected in a fluid-conducting manner with a coffee outlet (5) of the brewing unit (4). It is essential that the device furthermore has a fresh-water supply (2) and a fresh-water cooler (13) formed as an additional heat exchanger, wherein the fresh-water cooler (13) has at least one first and one second flow path that are connected thermally but not in a fluid conducting manner and the fresh-water supply (2) is connected in a fluid-conducting manner downstream with the second flow path of the fresh-water cooler (13), further downstream with the first flow path of the coffee cooler (14), and further downstream with the brewing unit (4) and the first flow path of the fresh-water cooler (13) is connected in a fluid-conducting manner with a coolant circuit of the cooling assembly. The invention further relates to a method for the production of cooled coffee.
摘要:
A container for holding and dispensing a liquid and/or dissolved active substance, for example a pharmaceutical or cosmetic active substance, has at least one dispensing organ (5) for dispensing, preferably in a portioned manner, the one active substance. Provision is also made for at least two holding chambers (9, 11) separated from one another, at least one of which contains the one active substance and at least one of which contains an at least largely active-substance-free liquid and/or a further active substance differing from the one active substance, wherein the dispensing organ is connected to the at least one chamber containing the active substance for dispensing purposes.
摘要:
The present invention relates to flexible facilities for supplying documents where the index to the documents is stored in a central archive but the documents themselves are stored in an external archiving system. The solution according to the invention is based on management of the addresses in the external archiving systems which is undertaken at the central archive. The approach adopted supports the specifying of any desired number of backup servers and, by allowing the configurable supply either of the address relation itself and/or of server address information attached to the list of search results, it provides a facility which supports the full range of document supply capabilities available when a central archive system is being used.
摘要:
The present invention relates to a process for improving the immunogenicity of an immunogen, an antigen or a hapten, when it is administered to a host, independently of the mode of administration, characterized in that the said antigen or hapten is coupled covalently to a support molecule in order to form a complex, and in that this support molecule is a polypeptide fragment which is able to bind specifically to mammalian serum albumin. The invention also relates to the use, as a medicament, of the product which can be obtained in this way.
摘要:
A process for preparing isoxazole-3,4-dicarboxylic acid derivatives of the formula I ##STR1## where R.sup.1 is hydrogen, alkyl, cycloalkyl or phenyl, or a 5- to 6-membered heterocyclic radical, and the organic radicals can have substituents which are inert under the reaction conditions;R.sup.2 is hydrogen, alkyl, cycloalkyl, benzyl or C.sub.3 -C.sub.6 -alkenyl;A is NR.sup.3 R.sup.4 where R.sup.3 is hydrogen or an aliphatic or cycloaliphatic radical and R.sup.4 is an aliphatic or cycloaliphatic radical or unsubstituted or substituted phenyl, or R.sup.3 forms together with R.sup.4 a 4- to 7-membered alkylene chain which can be interrupted by oxygen, sulfur or N-methyl, or is OR.sup.5 where R.sup.5 is alkyl, cycloalkyl, benzyl or alkenyl;by deprotonation of a CH-acid compound of the formula II ##STR2## using a base and reacting with hydroximyl chlorides of the formula III ##STR3## wherein a magnesium alcoholate of the formula IVMg(OR.sup.6 ).sub.2 IVwhere R.sup.6 is an aliphatic or cycloaliphatic radical is used for the deprotonation.