公开(公告)号：US20230133446A1

公开(公告)日：2023-05-04

申请号：US17906701

申请日：2021-01-29

Applicant: GLYCOM A/S

Inventor： Pierre CHASSAGNE

IPC: A23C9/20 ,  C07H3/06 ,  C12P19/18 ,  F26B5/12 ,  F26B15/18 ,  A23C1/03 ,  A23L33/125 ,  A23L3/48 ,  A23P10/22 ,  A23L33/00 ,  A23C9/146 ,  A23C9/142

Abstract: Various methods are provided for providing a solid HMO product, said methods including drum-drying, belt drying, preferably vacuum bed drying, or granulation. Solid HMO products are obtained via said methods, as well as solid HMO products per se. The methods can provide solid HMO products which are different to those achieved via other methods.

公开(公告)号：US20230114668A1

公开(公告)日：2023-04-13

申请号：US17906131

申请日：2021-03-12

Applicant: Glycom A/S

Inventor： Getachew S. MOLLA ,  Pierre CHASSAGNE

IPC: C07H3/06 ,  C07H1/06 ,  C13B30/02

Abstract: The invention relates to a method for selective crystallization of 2′-FL from an aqueous solution comprising 2′-FL and one or more other fucosylated carbohydrates by adding acetic acid to the solution.

公开(公告)号：US20220185837A1

公开(公告)日：2022-06-16

申请号：US17653819

申请日：2022-03-07

Applicant: GLYCOM A/S

Inventor： Martin MATWIEJUK ,  Pierre CHASSAGNE ,  Markus JONDELIUS HEDEROS

IPC: C07H1/06 ,  C07H13/04 ,  A61K31/702 ,  A23L33/125 ,  A23L33/00

Abstract: The invention relates to crystalline polymorphs of lacto-N-tetraose (LNT) and methods for making the same for use in pharmaceutical compositions, nutritional formulations and food supplements.

公开(公告)号：US20220056065A1

公开(公告)日：2022-02-24

申请号：US17415274

申请日：2019-12-19

Applicant: Glycom A/S

Inventor： Nikolay KHANZHIN ,  Markus JONDELIUS HEDEROS ,  Pierre CHASSAGNE

IPC: C07H1/06 ,  C12P19/26 ,  B01D15/12

Abstract: The invention relates to a method for the separation of two hydrophilic neutral oligosaccharides from each other with a chromatography on a bromine functionalized polystyrene cross-linked with divinylbenzene (BPS-DVB) stationary medium.

公开(公告)号：US20200325166A1

公开(公告)日：2020-10-15

申请号：US16913656

申请日：2020-06-26

Applicant: GLYCOM A/S

Inventor： Martin MATWIEJUK ,  Pierre CHASSAGNE ,  Markus JONDELIUS HEDEROS

IPC: C07H1/06 ,  C07H13/04 ,  A61K31/702 ,  A23L33/125 ,  A23L33/00

Abstract: The invention relates to crystalline polymorphs of lacto-N-tetraose (LNT) and methods for making the same for use in pharmaceutical compositions, nutritional formulations and food supplements.

公开(公告)号：US20200157132A1

公开(公告)日：2020-05-21

申请号：US16630372

申请日：2018-07-12

Applicant: GLYCOM A/S

Inventor： Benjámin PODÁNYI ,  Pierre CHASSAGNE ,  Martin MATWIEJUK ,  Markus JONDELIUS HEDEROS

IPC: C07H3/06 ,  C07H3/02 ,  C07H1/00

Abstract: It is provided i) an amorphous carbohydrate with improved chemical stability and/or physical features, ii) a method for producing an amorphous carbohydrate with improved chemical stability and/or physical features, and iii) a method for improving the chemical stability and/or the physical features of an amorphous carbohydrate.

公开(公告)号：US20180362569A1

公开(公告)日：2018-12-20

申请号：US16063367

申请日：2016-12-16

Applicant: Glycom A/S

Inventor： Martin MATWIEJUK ,  Pierre CHASSAGNE ,  Markus HEDEROS

IPC: C07H1/06 ,  C07H13/04 ,  A23L33/00 ,  A23L33/125

Abstract: The invention relates to crystalline polymorphs of lacto-N-tetraose (LNT) and methods for making the same for use in pharmaceutical compositions, nutritional formulations and food supplements.

公开(公告)号：US20170369920A1

公开(公告)日：2017-12-28

申请号：US15536537

申请日：2015-12-16

Applicant: Glycom A/S

Inventor： Gyula DEKANY ,  Györgyi OSZTROVSZKY ,  Martin MATWIEJUK ,  Pierre CHASSAGNE ,  Markus HEDEROS

IPC: C12P19/18 ,  C07H3/06 ,  C07H1/06

Abstract: The invention relates to a method for selective crystallization of 2′-FL from an aqueous solution comprising 2′-FL and one or more other fucosylated carbohydrates by adding acetic acid to the solution.

公开(公告)号：US20170340654A1

公开(公告)日：2017-11-30

申请号：US15532747

申请日：2015-12-04

Applicant: Glycom A/S

Inventor： Pierre CHASSAGNE ,  Martin MATWIEJUK ,  Markus HEDEROS ,  Györgyi OSZTROVSZKY ,  Gyula DEKANY

IPC: A61K31/702 ,  C07H3/06 ,  C07H1/06

CPC classification number: A61K31/702 ,  A61K31/7024 ,  C07H1/06 ,  C07H3/06 ,  C07H15/18 ,  Y02A50/473

Abstract: Crystalline difucosyllactose, useful in a pharmaceutical composition and a nutritional composition, is disclosed.