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公开(公告)号：US20180230233A1
公开(公告)日：2018-08-16
申请号：US15893238
申请日：2018-02-09
Applicant: Genentech, Inc.
Inventor： Xiaocheng CHEN , Mark DENNIS , Janet JACKMAN , James T. KOERBER , Mason LU , Henry R. MAUN , Kathila RAJAPAKSA , Saroja RAMANUJAN , Tracy STATON , Lawren WU , Tangsheng YI
Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.
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公开(公告)号：US20170260292A1
公开(公告)日：2017-09-14
申请号：US15435658
申请日：2017-02-17
Applicant: Genentech, Inc.
Inventor： Mark DENNIS , Ryan Jefferson WATTS , Yunhua Yu ZUCHERO , Yin ZHANG
Abstract: The present invention relates to antibodies that bind blood brain barrier receptors (BBB-R) and methods of using the same.
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公开(公告)号：US20160296634A1
公开(公告)日：2016-10-13
申请号：US14945980
申请日：2015-11-19
Applicant: GENENTECH, INC.
Inventor： Mark DENNIS , William MALLET , Paul POLAKIS
IPC: A61K47/48 , A61K31/555 , C07K16/30 , A61K31/4196 , A61K31/519 , A61K31/517 , A61K31/7068 , A61K31/513
CPC classification number: A61K47/6803 , A61K31/337 , A61K31/4025 , A61K31/4196 , A61K31/513 , A61K31/517 , A61K31/519 , A61K31/537 , A61K31/555 , A61K31/7068 , A61K31/7072 , A61K38/07 , A61K38/08 , A61K45/06 , A61K47/6817 , A61K47/6835 , A61K47/6851 , A61K2039/505 , C07K16/3015 , C07K16/303 , C07K16/3069 , C07K16/3092 , C07K2317/24 , C07K2317/55 , C07K2317/565 , Y10T428/13
Abstract: The invention is directed to antibody drug conjugate compositions of matter useful for the diagnosis and treatment of tumors in mammals and to methods of using those compositions of matter for the same.
Abstract translation: 本发明涉及可用于诊断和治疗哺乳动物肿瘤的物质的抗体药物共轭组合物，以及使用这些物质组合物的方法。
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公开(公告)号：US20160168261A1
公开(公告)日：2016-06-16
申请号：US14953763
申请日：2015-11-30
Applicant: Genentech, Inc.
Inventor： Mark DENNIS , Jan MARIK , Paul POLAKIS , Bonnee RUBINFELD , Simon WILLIAMS
CPC classification number: C07K16/40 , A61K47/6811 , A61K47/6871 , A61K51/1072 , A61K51/1075 , A61K51/1093 , A61K51/1096 , A61K2039/505 , C07B59/008 , C07B2200/05 , C07K16/3069 , C07K2317/24 , C07K2317/565 , C07K2317/92 , G01N33/534 , G01N33/57492 , G01N33/60 , G01N33/6893
Abstract: Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of detecting or determining the presence of STEAP-1 proteins are provided.
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公开(公告)号：US20240309088A1
公开(公告)日：2024-09-19
申请号：US18392623
申请日：2023-12-21
Applicant: Genentech, Inc.
Inventor： Yvonne CHEN , Mark DENNIS , David DORNAN , Kristi ELKINS , Jagath Reddy JUNUTULA , Andrew POLSON , Bing ZHENG
IPC: C07K16/28 , A61K31/537 , A61K38/05 , A61K39/00 , A61K39/395 , A61K45/06 , A61K47/68 , A61K51/10 , C07K16/30 , G01N33/574
CPC classification number: C07K16/2803 , A61K31/537 , A61K38/05 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6811 , A61K47/6849 , A61K47/6867 , A61K51/1027 , C07K16/3061 , G01N33/57492 , A61K2039/505 , C07K2317/24 , C07K2317/34 , C07K2317/40 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92 , Y02A50/30
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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Patent Agency Ranking
公开(公告)号：US20220251197A1
公开(公告)日：2022-08-11
申请号：US17725417
申请日：2022-04-20
Applicant: Genentech, Inc.
Inventor： Yvonne CHEN , Mark DENNIS , David DORNAN , Kristi ELKINS , Jagat Reddy JUNUTULA , Andrew POLSON , Bing ZHENG
IPC: C07K16/28 , A61K51/10 , A61K47/68 , A61K39/395 , A61K45/06 , A61K31/537 , A61K38/05 , C07K16/30 , G01N33/574
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US20220023437A1
公开(公告)日：2022-01-27
申请号：US17234695
申请日：2021-04-19
Applicant: Genentech, Inc.
Inventor： Yvonne CHEN , Mark DENNIS , Kristi ELKINS , Jagath Reddy JUNUTULA , Andrew POLSON , Bing ZHENG
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US20180344864A1
公开(公告)日：2018-12-06
申请号：US15846083
申请日：2017-12-18
Applicant: Genentech, Inc.
Inventor： Mark DENNIS , William MALLET , Paul POLAKIS
IPC: A61K47/68 , A61K31/7068 , A61K31/337 , C07K16/30 , A61K45/06 , A61K38/08 , A61K38/07 , A61K31/7072 , A61K31/555 , A61K31/537 , A61K31/519 , A61K31/517 , A61K31/513 , A61K31/4196 , A61K31/4025 , A61K39/00
CPC classification number: A61K31/7068 , A61K31/337 , A61K31/4025 , A61K31/4196 , A61K31/513 , A61K31/517 , A61K31/519 , A61K31/537 , A61K31/555 , A61K31/7072 , A61K38/07 , A61K38/08 , A61K45/06 , A61K47/6803 , A61K47/6817 , A61K47/6835 , A61K47/6851 , A61K2039/505 , C07K16/3015 , C07K16/303 , C07K16/3069 , C07K16/3092 , C07K2317/24 , C07K2317/55 , C07K2317/565 , Y10T428/13
Abstract: The invention is directed to antibody drug conjugate compositions of matter useful for the diagnosis and treatment of tumors in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US20170369869A1
公开(公告)日：2017-12-28
申请号：US15690544
申请日：2017-08-30
Applicant: Genentech, Inc.
Inventor： Devin TESAR , Xiaocheng CHEN , Mark DENNIS , Isidro HOTZEL
CPC classification number: C12N15/1037 , C07K16/00 , C07K2319/02 , C07K2319/40 , C07K2319/735 , C12N15/70 , C12N15/74 , C12N15/85 , C12N2820/10 , C12N2820/55 , C12N2820/85 , C12N2830/42 , C12N2830/55 , C12N2830/85 , C12P21/02
Abstract: The invention provides an expression and secretion system, and methods of using the same, for the expression and secretion of one fusion protein in prokaryotic cells and a second fusion protein in eukaryotic cells. Also provided herein are nucleic acid molecules, vectors and host cells comprising such vectors and nucleic acid molecules.
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公开(公告)号：US20170121424A1
公开(公告)日：2017-05-04
申请号：US15289485
申请日：2016-10-10
Applicant: Genentech, Inc.
Inventor： Mark DENNIS , Jan MARIK , Paul POLAKIS , Bonnee RUBINFELD , Simon WILLIAMS
IPC: C07K16/40 , C07B59/00 , G01N33/574 , G01N33/534 , G01N33/60 , A61K51/10 , C07K16/30
CPC classification number: C07K16/40 , A61K47/6811 , A61K47/6871 , A61K51/1072 , A61K51/1075 , A61K51/1093 , A61K51/1096 , A61K2039/505 , C07B59/008 , C07B2200/05 , C07K16/3069 , C07K2317/24 , C07K2317/565 , C07K2317/92 , G01N33/534 , G01N33/57492 , G01N33/60 , G01N33/6893
Abstract: Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of detecting or determining the presence of STEAP-1 proteins are provided.
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