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29 条记录 (耗时 0.025 秒)

    REMOTE NON-INVASIVE PARAMETER SENSING SYSTEM AND METHOD
    13.
    发明申请
    REMOTE NON-INVASIVE PARAMETER SENSING SYSTEM AND METHOD 审中-公开
    远程非入侵参数传感系统及方法

    公开(公告)号：US20120283575A1

    公开(公告)日：2012-11-08

    申请号：US13501081

    申请日：2010-10-12

    申请人： Govind Rao ,  Yordan Kostov ,  Leah Tolosa ,  Hung Lam

    发明人： Govind Rao ,  Yordan Kostov ,  Leah Tolosa ,  Hung Lam

    IPC分类号： A61B5/01 ,  A61B6/00

    CPC分类号： A61B5/015

    摘要： A remote parameter sensing system is provide that includes a gel sensor, a light source, a detector and a controller 140. The gel sensor is in contact with a surface where the parameter is to be measured, and is preferably a gel that is embedded with a chemical that emits light 160 (via, for example, fluorescence) when it is excited by excitation light from the light source at an appropriate excitation frequency. The chemical properties of the gel sensor are such that at least one characteristic of the emission light (such as, for example, emission intensity) varies as a function of variations in the parameter being measured. The system is particularly suited for use as remote body temperature sensing system in incubators and radiant warmers for infant and neonatal care.

    摘要翻译： 提供了一种远程参数感测系统，其包括凝胶传感器，光源，检测器和控制器140.凝胶传感器与要测量参数的表面接触，并且优选地是嵌入 当通过来自光源的激发光以适当的激发频率激发时，发出光160（通过例如荧光）的化学品。 凝胶传感器的化学性质使得发射光（例如发光强度）的至少一个特性随着被测参数的变化而变化。 该系统特别适用于孵化器中的远程体温感测系统和用于婴儿和新生儿护理的辐射加热器。

    NON-INVASIVE SENSING OF BIOPROCESS PARAMETERS
    14.
    发明申请
    NON-INVASIVE SENSING OF BIOPROCESS PARAMETERS 有权
    生物参数的非入侵感知

    公开(公告)号：US20120171760A1

    公开(公告)日：2012-07-05

    申请号：US13378033

    申请日：2010-06-21

    申请人： Govind Rao ,  Yordan Kostov ,  Leah Tolosa

    发明人： Govind Rao ,  Yordan Kostov ,  Leah Tolosa

    IPC分类号： C12M1/34

    CPC分类号： C12M23/00 ,  C12M23/20 ,  C12M41/00 ,  C12M41/26 ,  C12M41/34

    摘要： A system and method for measuring at least one bioprocess parameter utilizes a barrier that separates an external sensor from a culture medium. The barrier allows analytes to diffuse in and out of the culture vessel, thereby allowing the bioprocess parameter to be measured non-invasively by the external sensor.

    摘要翻译： 用于测量至少一个生物过程参数的系统和方法利用将外部传感器与培养基分离的屏障。 屏障允许分析物扩散进出培养容器，从而允许外部传感器非侵入性地测量生物过程参数。

    Bioreactor and bioprocessing technique
    15.
    发明授权
    Bioreactor and bioprocessing technique 有权

    公开(公告)号：US06673532B2

    公开(公告)日：2004-01-06

    申请号：US09928662

    申请日：2001-08-14

    申请人： Govind Rao

    发明人： Govind Rao

    IPC分类号： C12Q100

    CPC分类号： G01N21/253 ,  C12M23/12 ,  C12M41/26 ,  C12M41/32 ,  C12M41/34 ,  G01N21/643 ,  G01N21/6452 ,  G01N21/76 ,  G01N21/82 ,  G01N33/52 ,  G01N2021/6482

    摘要： The inventive bioprocessing system (and technique) relies on non-invasive optical chemical sensing technology wherein an optical excitation source excites an optical chemical sensor. The optical chemical sensor then emits luminescence or absorbs light which is measured by a detector. The luminescence emitted from the chemical sensor or the amount of light absorbed by the chemical sensor is related to the concentration of an analyte, such as oxygen. If the luminescence emitted changes, or if the amount of light absorbed changes, then the concentration of the analyte has changed. Using such a system to measure and adjust multiple parameters at one time allows one to efficiently and cost-effectively determine optimal conditions for a given cell type and/or cell environment, for example. By combining cell cultivation with optical chemical sensing technology, cultivation can be successfully and rapidly performed, controlled and monitored in small volumes in an automated, parallel fashion at less expense than current bioprocess techniques.

    NON-INVASIVE ANALYTE SENSING SYSTEM AND METHOD
    18.
    发明申请
    NON-INVASIVE ANALYTE SENSING SYSTEM AND METHOD 有权
    非入侵分析仪感测系统及方法

    公开(公告)号：US20130281806A1

    公开(公告)日：2013-10-24

    申请号：US13823903

    申请日：2011-09-30

    申请人： Govind Rao ,  Yordan Kostov ,  Xudong Ge ,  Leah Tolosa ,  Hyung Woo ,  Rose Viscardi

    发明人： Govind Rao ,  Yordan Kostov ,  Xudong Ge ,  Leah Tolosa ,  Hyung Woo ,  Rose Viscardi

    IPC分类号： A61B5/1455

    CPC分类号： A61B5/14552 ,  A61B5/6807 ,  A61B5/6829

    摘要： A non-invasive gas analyte sensing and monitoring system and method is provided that is particularly applicable to transcutaneous monitoring of arterial blood gases in a mammal. The system and method relies on diffusion of the analyte to be measured into a diffusion chamber and remote sensing of the analyte in the diffusion chamber using optical chemical sensors and associated optoelectronics.

    摘要翻译： 提供一种非侵入性气体分析物感测和监测系统和方法，其特别适用于哺乳动物的动脉血气的经皮监测。 该系统和方法依赖于待测量分析物扩散到扩散室中，并使用光学化学传感器和相关联的光电子学来远程检测扩散室中的分析物。

    INTEGRATED OXYGEN MEASUREMENT AND CONTROL FOR STATIC CULTURE VESSELS
    20.
    发明申请
    INTEGRATED OXYGEN MEASUREMENT AND CONTROL FOR STATIC CULTURE VESSELS 审中-公开
    一体化氧气测量和静态文化船的控制

    公开(公告)号：US20110065084A1

    公开(公告)日：2011-03-17

    申请号：US12991947

    申请日：2009-05-12

    申请人： Govind Rao ,  Yordan Kostov

    发明人： Govind Rao ,  Yordan Kostov

    IPC分类号： C12Q3/00 ,  C12M1/36

    CPC分类号： C12M27/16 ,  C12M23/08 ,  C12M41/34

    摘要： A system and method for measuring and controlling oxygen in a culture vessel utilizes a non-invasive oxygen sensor and an agitator. A controller controls the agitator based on feedback supplied by the oxygen sensor. The agitator is used to increase oxygen transport into the liquid phase thereby raising the level of oxygen in the culture medium. The agitator driven equilibration results in precise control of the culture medium oxygen.

    摘要翻译： 用于测量和控制培养容器中的氧气的系统和方法利用非侵入性氧传感器和搅拌器。 控制器根据氧传感器提供的反馈来控制搅拌器。 搅拌器用于增加氧气输送到液相中，从而提高培养基中的氧气含量。 搅拌器驱动的平衡导致培养基氧气的精确控制。