摘要:
Improved Pseudomonas exotoxins of low animal toxicity and high cytocidal activity are described. Substitution of positively charged amino acid residues with an amino acid residue without a positive charge provides markedly changed exotoxins. Conjugation of the new exotoxins with suitable targeting agents provides cytocidal specificity for killing desired cellular entities.
摘要:
A waterboard with externally adjustable stiffness includes a stringer assembly having a rotatable beam to modulate the stiffness of the beam in a selected direction to impart a desired stiffness to the waterboard.
摘要:
A method of testing a semiconductor circuit including a pair of contact pads, a biasing circuit for applying a voltage to the pair of contact pads, and a sensing circuit for providing a signal indicative of the voltage applied across the contact pads. The method includes determining a voltage gain and voltage offset of the sensing circuit while the biasing circuit is disabled. The method also includes enabling the biasing circuit to produce a voltage across the contact pads and determining, from the resulting output voltage produced by the sensing circuit, an actual output voltage produced by the biasing circuit at the contact pads based on the determined voltage gain and voltage offset of the sensing circuit.
摘要:
An embodiment of the present invention may provide a method and system for event notification, performance and/or risk assessment based on mission impact that may be due to actual and/or potential info-structure disruptions. In one embodiment of the present invention, one or more network event messages may be received from a source or multiple sources. An operational mission impacted by a network event may be identified based on a received network event message and mapping with an operational architecture task identifier associated with the impacted operational mission and an element identifier associated with a source element.
摘要:
A chimeric gene directing the synthesis of hybrid recombinant fusion protein in a suitable expression vector has been constructed. The fusion protein possesses the property of selective cytotoxicity against specific virus-infected cells. A CD4(178)-PE40 hybrid fusion protein has been made for selectively killing HIV-infected cells.
摘要:
A chimeric gene directing the synthesis of hybrid recombinant fusion protein in a suitable expression vector has been constructed. The fusion protein possesses the property of selective cytotoxicity against specific virus-infected cells. A CD4(178)-PE40 hybrid fusion protein has been made for selectively killing HIV-infected cells.
摘要:
Various embodiments of the present invention provide systems and methods for determining contact with a storage medium. As an example, a data storage system is disclosed that includes: a head assembly and a data processing circuit. The head includes a head disk interface sensor operable to provide a contact signal indicating contact between the head and a storage medium disposed in relation to the head. The data processing circuit is operable to process the contact signal to yield an indication of a contact between the storage medium and the head.
摘要:
Various embodiments of the present invention provide systems and methods for determining contact with a storage medium. As an example, a data storage system is disclosed that includes: a head assembly and a data processing circuit. The head includes a head disk interface sensor operable to provide a contact signal indicating contact between the head and a storage medium disposed in relation to the head. The data processing circuit is operable to process the contact signal to yield an indication of a contact between the storage medium and the head.
摘要:
A collapsible stroller like device is described. The device includes a base portion to permit a child to be pushed or pulled across the snow or other surface.
摘要:
The present invention includes a children's toy waterslide incorporating a sliding surface, an obstacle region, a splash zone, and an obstacle or obstacles. The sliding surface extends through the obstacle region and into the splash zone. Water may be sprayed along the length of the sliding surface by a sprinkler tube. The obstacle or obstacles may be placed on or over the sliding surface in the obstacle region. The obstacle may be a “limbo stick” bar, a water tunnel with dump bucket, and/or inflatable bowling-pin-type objects.