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公开(公告)号：US07754057B2
公开(公告)日：2010-07-13
申请号：US10902681
申请日：2004-07-29
CPC分类号： C25B1/26
摘要： A chlorine dioxide solution generator, which injects a chlorine dioxide solution into a pressurized fluid system, including an absorption loop for effecting the dissolution of chlorine dioxide into a liquid stream. The chlorine dioxide gas source can include an anolyte loop and a catholyte loop. The generator avoids or eliminates the introduction of air or other gases that can cause corrosion in the process distribution system.
摘要翻译： 二氧化氯溶液发生器，其将二氧化氯溶液注入加压流体系统中，包括用于将二氧化氯溶解到液体流中的吸收回路。 二氧化氯气体源可以包括阳极电解液回路和阴极电解液回路。 发电机避免或消除引入可能在过程分配系统中引起腐蚀的空气或其他气体。
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12.发明申请PRESSURE-ASSISTED MOLECULAR RECOVERY (PAMR) OF BIOMOLECULES, PRESSURE-ASSISTED ANTIGEN RETRIEVAL (PAAR), AND PRESSURE-ASSISTED TISSUE HISTOLOGY (PATH) 有权生物分子的压力辅助分子恢复（PAMR），压力辅助抗体检索（PAAR）和压力协助组织学（PATH）公开(公告)号：US20100136613A1
公开(公告)日：2010-06-03
申请号：US12630746
申请日：2009-12-03
IPC分类号： G01N1/28
CPC分类号： A01N1/0231 , G01N1/30
摘要： A method is disclosed for reversing fixation-induced cross-linking in tissue specimens that have been preserved for histological examination. The method involves placing the fixed tissue in a liquid under elevated temperature and pressure conditions that are sufficient to reverse the fixation-induced cross-linking, restore antigenicity to proteins, and permit improved molecular and proteomic analysis of the preserved tissue specimen. Methods are also disclosed for processing tissues for histological examination under elevated pressure conditions that enhance the perfusion of liquid reagents into the tissue and reduce overall processing times.
摘要翻译： 公开了一种用于逆转已经保留用于组织学检查的组织标本中固定诱导交联的方法。 该方法包括将固定组织置于液体中，该温度和压力条件足以逆转固定诱导的交联，恢复对蛋白质的抗原性，并允许改进保藏组织标本的分子和蛋白质组学分析。 还公开了用于处理在升高的压力条件下进行组织学检查的组织的方法，其增强液体试剂灌注到组织中并减少总体加工时间。
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13.发明申请REPOSITIONABLE ADHESIVE-BACKED PHOTOGRAPHS AND PHOTO MEDIA AND METHODS OF MAKING 审中-公开可记录的粘合背景照片和照片媒体及制作方法公开(公告)号：US20080087379A1
公开(公告)日：2008-04-17
申请号：US11854633
申请日：2007-09-13
CPC分类号： G03C11/14 , B32B37/1207 , C09J7/35 , C09J7/385 , C09J2201/128 , C09J2201/134 , C09J2423/00 , C09J2433/00 , C09J2477/00 , G03G7/004 , G03G7/0046 , Y10T156/10
摘要： A method of making a repositionable adhesive backed photo media is provided. The method includes the steps of (a) providing an imageable substrate or providing a photograph; (b) providing an attachment mechanism having a carrier film with opposing first and second surfaces; a thermally activating adhesive disposed on the first surface; a repositionable adhesive disposed on the second surface; and a liner disposed on the repositionable adhesive; (c) stacking the imageable substrate or stacking the photograph with the attachment mechanism; and (4) exposing the stack to heat causing the thermally activating adhesive to bond to the imageable substrate or the photograph.
摘要翻译： 提供了一种制备可重新定位的粘合剂背衬的照相介质的方法。 该方法包括以下步骤：（a）提供可成像的基底或提供照片; （b）提供具有相对的第一和第二表面的载体膜的附接机构; 设置在所述第一表面上的热活化粘合剂; 设置在所述第二表面上的可重新定位的粘合剂; 和设置在可重定位粘合剂上的衬垫; （c）堆叠可成像的基板或将照片与附着机构堆叠; 和（4）将堆叠暴露于热，导致热活化粘合剂结合到可成像的基底或照片上。
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公开(公告)号：US06910667B2
公开(公告)日：2005-06-28
申请号：US10172962
申请日：2002-06-17
申请人： Timothy J. O'Leary , Eiji Mizuno
发明人： Timothy J. O'Leary , Eiji Mizuno
CPC分类号： B42F21/06 , B32B7/02 , B42F21/00 , C09J7/22 , C09J7/29 , C09J7/38 , C09J2201/162 , C09J2201/618 , Y10T428/28 , Y10T428/2848 , Y10T428/2861 , Y10T428/2891
摘要： A stretch releasable adhesive strip includes an extensible backing layer including a first adhesive region and a flexible support layer attached to the backing layer adjacent the first adhesive region that includes a second adhesive region of a repositionable pressure sensitive adhesive. To make the adhesive strip easier to handle and write on, the support layer is stiffer than the backing layer.
摘要翻译： 拉伸可剥离粘合剂条包括可延伸背衬层，其包括第一粘合区域和附接到邻近第一粘合剂区域的背衬层的柔性支撑层，该第一粘合剂区域包括可重新定位的压敏粘合剂的第二粘合剂区域。 为了使粘合带易于处理和写入，支撑层比背衬层更硬。
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公开(公告)号：US5524929A
公开(公告)日：1996-06-11
申请号：US432824
申请日：1995-05-02
申请人： John J. Emmel , Glen H. Bayer, Jr. , David C. Windorski , Timothy J. O'Leary , Mary K. Miller-Bruns
发明人： John J. Emmel , Glen H. Bayer, Jr. , David C. Windorski , Timothy J. O'Leary , Mary K. Miller-Bruns
摘要： A binding assembly including (1) a plurality of support strips; (2) layers of pressure sensitive adhesive (which could be repositionable, removable or permanent pressure sensitive adhesive) along front surfaces of the support strips; and (3) layers of release material on a rear surfaces of the support strips. The support strips are adhered together to form a support strip stack with inner edges of the support strips in alignment, with the layers of pressure sensitive adhesive on the support strips adhered to the layers of release material on adjacent support strips, and with the front surfaces of the support strips uppermost in the support strip stack. The binding assembly further includes binding means along the inner edges of the support strips that affords separation of the support strips and revolving of the support strips relative to each other around axes generally parallel to their inner edges. Only tension applied through a paper sheet adhered along the full length of the layer of pressure sensitive adhesive on the uppermost one of the support strips adhered in the support strip stack can be used to separate that one support strip from an adjacent support strip adhered to the layer of release material on the front surface of that one support strip and cause revolving of that one support strip away from the support strip from which that one support strip was separated.
摘要翻译： 一种装订组件，包括（1）多个支撑条; （2）压敏粘合剂层（其可以是可重新定位的，可移除的或永久的压敏粘合剂）沿支撑条的前表面; 和（3）在支撑条的后表面上的释放材料层。 支撑条粘合在一起以形成支撑条叠层，其中支撑条的内边缘对齐，支撑条上的压敏粘合剂层粘附到相邻支撑条上的释放材料层上，并且与前表面 的支撑条最上面的支撑条堆叠。 装订组件还包括沿着支撑条的内边缘的装订装置，其提供支撑条的分离并且支撑条相对于彼此围绕大致平行于其内边缘的轴线旋转。 只有沿着压敏粘合剂层全长附着的纸张施加在附着在支撑条堆叠中的最上面的一个支撑条上的张力可用于将一个支撑条与附接到 在该一个支撑条的前表面上的释放材料层，并且使得该一个支撑条的旋转远离支撑条，该支撑条从该支撑条分离。
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公开(公告)号：US4964662A
公开(公告)日：1990-10-23
申请号：US498414
申请日：1990-03-26
申请人： Timothy J. O'Leary , Roger R. Brown
发明人： Timothy J. O'Leary , Roger R. Brown
IPC分类号： E05C19/18
CPC分类号： E05C19/182 , Y10T292/388
摘要： A press fitted stud on one end of a metal strip is hooked into the opening of a striker plate in a door jamb and the strip extends in the space between the jamb and the edge of the door past the jamb and closed door. The extended end of the plate has holes for receiving a knurled locking pin which holds a locking plate tightly against the closed door and the door jamb to keep the door securely closed. Resilient pads of different thickness and compressibility on the locking plate facing the door keep the door tightly closed.
摘要翻译： 在金属条的一端上的压配螺栓被钩在门边框中的撞针板的开口中，并且该条在门和边缘之间的空间中延伸通过侧板和闭门。 板的延伸端具有用于接收滚花锁定销的孔，其将锁定板紧紧地保持在闭合的门和门侧柱上，以保持门牢固地关闭。 在面向门的锁定板上具有不同厚度和压缩性的弹性垫保持门紧密关闭。
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17.发明授权Pressure-assisted molecular recovery (PAMR) of biomolecules, pressure-assisted antigen retrieval (PAAR), and pressure-assisted tissue histology (PATH) 有权生物分子的压力辅助分子回收（PAMR），压力辅助抗原回收（PAAR）和压力辅助组织组织学（PATH）公开(公告)号：US08481283B2
公开(公告)日：2013-07-09
申请号：US13613618
申请日：2012-09-13
IPC分类号： G01N1/30
CPC分类号： A01N1/0231 , G01N1/30
摘要： A method is disclosed for reversing fixation-induced cross-linking in tissue specimens that have been preserved for histological examination. The method involves placing the fixed tissue in a liquid under elevated temperature and pressure conditions that are sufficient to reverse the fixation-induced cross-linking, restore antigenicity to proteins, and permit improved molecular and proteomic analysis of the preserved tissue specimen. Methods are also disclosed for processing tissues for histological examination under elevated pressure conditions that enhance the perfusion of liquid reagents into the tissue and reduce overall processing times.
摘要翻译： 公开了一种用于逆转已经保留用于组织学检查的组织标本中固定诱导交联的方法。 该方法包括将固定组织置于液体中，该温度和压力条件足以逆转固定诱导的交联，恢复对蛋白质的抗原性，并允许改进保藏组织标本的分子和蛋白质组学分析。 还公开了用于处理在升高的压力条件下进行组织学检查的组织的方法，其增强液体试剂灌注到组织中并减少总体加工时间。
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18.发明申请PRESSURE-ASSISTED MOLECULAR RECOVERY (PAMR) OF BIOMOLECULES, PRESSURE-ASSISTED ANTIGEN RETRIEVAL (PAAR), AND PRESSURE-ASSISTED TISSUE HISTOLOGY (PATH) 有权生物分子的压力辅助分子恢复（PAMR），压力辅助抗体检索（PAAR）和压力协助组织学（PATH）公开(公告)号：US20130011854A1
公开(公告)日：2013-01-10
申请号：US13613618
申请日：2012-09-13
IPC分类号： G01N1/30
CPC分类号： A01N1/0231 , G01N1/30
摘要： A method is disclosed for reversing fixation-induced cross-linking in tissue specimens that have been preserved for histological examination. The method involves placing the fixed tissue in a liquid under elevated temperature and pressure conditions that are sufficient to reverse the fixation-induced cross-linking, restore antigenicity to proteins, and permit improved molecular and proteomic analysis of the preserved tissue specimen. Methods are also disclosed for processing tissues for histological examination under elevated pressure conditions that enhance the perfusion of liquid reagents into the tissue and reduce overall processing times.
摘要翻译： 公开了一种用于逆转已经保留用于组织学检查的组织标本中固定诱导交联的方法。 该方法包括将固定组织置于液体中，该温度和压力条件足以逆转固定诱导的交联，恢复对蛋白质的抗原性，并允许改进保藏组织标本的分子和蛋白质组学分析。 还公开了用于处理在升高的压力条件下进行组织学检查的组织的方法，其增强液体试剂灌注到组织中并减少总体加工时间。
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19.发明授权Pressure-assisted molecular recovery (PAMR) of biomolecules, pressure-assisted antigen retrieval (PAAR), and pressure-assisted tissue histology (PATH) 有权生物分子的压力辅助分子回收（PAMR），压力辅助抗原回收（PAAR）和压力辅助组织组织学（PATH）公开(公告)号：US08288122B2
公开(公告)日：2012-10-16
申请号：US12630746
申请日：2009-12-03
IPC分类号： G01N1/30
CPC分类号： A01N1/0231 , G01N1/30
摘要： A method is disclosed for reversing fixation-induced cross-linking in tissue specimens that have been preserved for histological examination. The method involves placing the fixed tissue in a liquid under elevated temperature and pressure conditions that are sufficient to reverse the fixation-induced cross-linking, restore antigenicity to proteins, and permit improved molecular and proteomic analysis of the preserved tissue specimen. Methods are also disclosed for processing tissues for histological examination under elevated pressure conditions that enhance the perfusion of liquid reagents into the tissue and reduce overall processing times.
摘要翻译： 公开了一种用于逆转已经保留用于组织学检查的组织标本中固定诱导交联的方法。 该方法包括将固定组织置于液体中，该温度和压力条件足以逆转固定诱导的交联，恢复对蛋白质的抗原性，并允许改进保藏组织标本的分子和蛋白质组学分析。 还公开了用于处理在升高的压力条件下进行组织学检查的组织的方法，其增强液体试剂灌注到组织中并减少总体加工时间。
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公开(公告)号：US07662568B2
公开(公告)日：2010-02-16
申请号：US12399060
申请日：2009-03-06
IPC分类号： C12Q1/68
CPC分类号： A61K9/127 , C12Q1/6806 , C12Q2563/161
摘要： Immunoliposomes and use thereof in highly specific and sensitive nucleic acid amplification assays relying on amplification of specific nucleic acid sequences released from encapsulation within a liposome after a receptor on the liposome couples with a targeted analyte/antigen immobilized on a select surface. The immunoliposome nucleic acid amplification assay permits both quantitative and qualitative analyte detection.
摘要翻译： 免疫脂质体及其在高度特异性和灵敏的核酸扩增测定中的应用，其依赖于在脂质体上的受体之后从包封在脂质体内释放的特异性核酸序列的扩增与固定在选择表面上的靶向分析物/抗原相结合。 免疫脂质体核酸扩增测定允许定量和定性分析物检测。
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