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30 条记录 (耗时 0.029 秒)

    Respiratory nitrate reductase alpha subunit
    11.
    发明授权
    Respiratory nitrate reductase alpha subunit 失效
    呼吸道硝酸还原酶α亚基

    公开(公告)号：US06316237B1

    公开(公告)日：2001-11-13

    申请号：US09579376

    申请日：2000-05-26

    申请人： Thomas B Mathie ,  Christopher M Traini ,  Stephanie Van Horn ,  Richard L Warren

    发明人： Thomas B Mathie ,  Christopher M Traini ,  Stephanie Van Horn ,  Richard L Warren

    IPC分类号： C12N900

    CPC分类号： C12N9/0044

    摘要： The invention provides respiratory nitrate reductase alpha subunit polypeptides and polynucleotides encoding respiratory nitrate reductase alpha subunit polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing respiratory nitrate reductase alpha subunit polypeptides to screen for antibacterial compounds.

    摘要翻译： 本发明提供了呼吸性硝酸还原酶α亚基多肽和编码呼吸性硝酸还原酶α亚单位多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用呼吸性硝酸还原酶α亚基多肽筛选抗菌化合物的方法。

    cDNA clone HDPB130 that encodes a novel human 7-transmembrane receptor
    13.
    发明授权
    cDNA clone HDPB130 that encodes a novel human 7-transmembrane receptor 失效
    编码新型人7-跨膜受体的cDNA克隆HDPB130

    公开(公告)号：US06221627B1

    公开(公告)日：2001-04-24

    申请号：US08806263

    申请日：1997-02-24

    申请人： Ganesh Sathe ,  Stephanie Van Horn

    发明人： Ganesh Sathe ,  Stephanie Van Horn

    IPC分类号： C12N1512

    CPC分类号： C07K14/705 ,  G01N2333/726

    摘要： HDPBI30 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HDPBI30 polypeptides and polynucleotides in the design of protocols for the treatment of infections such as bacterial, fungal, protozoan and viral infections, particularly infections caused by HIV-1 or HIV-2; pain; cancers; anorexia; bulimia; asthma; Parkinson's disease; acute heart failure; hypotension; hypertension; urinary retention; osteoporosis; angina pectoris; myocardial infarction; ulcers; asthma; allergies; benign prostatic hypertrophy; and psychotic and neurological disorders, including anxiety, schizophrenia, manic depression, delirium, dementia, severe mental retardation and dyskinesias, such as Huntington's disease or Gilles dela Tourett's syndrome, among others and diagnostic assays for such conditions.

    摘要翻译： 公开了HDPBI30多肽和多核苷酸以及通过重组技术产生此类多肽的方法。 还公开了在设计用于治疗感染例如细菌，真菌，原生动物和病毒感染，特别是由HIV-1或HIV-2引起的感染的方案中使用HDPBI30多肽和多核苷酸的方法; 疼痛; 癌症; 厌食症 贪食 哮喘; 帕金森病 急性心力衰竭 低血压 高血压; 尿潴留 骨质疏松症 心绞痛; 心肌梗死; 溃疡 哮喘; 过敏 良性前列腺肥大; 以及精神病和神经障碍，包括焦虑，精神分裂症，躁狂抑郁症，del妄，痴呆，严重的精神发育迟滞和运动障碍，如亨廷顿病或Gilles dela Tourett综合征以及这些病症的诊断测定。