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公开(公告)号：US20060292133A1
公开(公告)日：2006-12-28
申请号：US11311632
申请日：2005-12-20
CPC分类号： C12R1/01 , A23C9/1234 , A23L33/135 , A23V2002/00 , A23Y2220/77 , A61K39/09 , A61K2039/52 , A61K2039/542 , C12N1/20 , Y10S435/822 , Y10S435/853 , A23V2200/3204 , A23V2200/324
摘要： Lactobacillus salivarius is useful in the prophylaxis or treatment of undesirable inflammatory activity, especially gastrointestinal inflammatory activity such as inflammatory bowel disease or irritable bowel syndrome. The inflammatory activity may also be due to cancer. The Lactobacillus salivarius is of human origin isolated from resected and washed human gastrointestinal tract. One such strain is UCC 118 described in WO-A-9835014.
摘要翻译： 唾液乳杆菌可用于预防或治疗不希望的炎性活动，特别是胃肠炎症活动，如炎性肠病或肠易激综合征。 炎症活动也可能是由于癌症。 唾液乳杆菌是从切除和洗涤的人类胃肠道分离的人源。 一种这样的菌株是在WO-A-9835014中描述的UCC 118。
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公开(公告)号：US07390519B2
公开(公告)日：2008-06-24
申请号：US11105590
申请日：2005-04-14
申请人： John Kevin Collins , Gerald Christopher O'Sullivan , Liam O'Mahony , Fergus Shanahan , Barry Kiely
发明人： John Kevin Collins , Gerald Christopher O'Sullivan , Liam O'Mahony , Fergus Shanahan , Barry Kiely
CPC分类号： A61K35/747 , A23L33/135 , A23Y2220/79 , C12N1/20 , C12R1/225
摘要： A Lactobacillus salivarius strain, AH102, AH103, AH105, AH109 or AH110 or mutants or variants thereof are useful in the prophylaxis and/or treatment of inflammatory activity especially undesirable gastrointestinal inflammatory activity, such as inflammatory bowel disease or irritable bowel syndrome.
摘要翻译： A唾液乳杆菌菌株AH102，AH103，AH105，AH109或AH110或其突变体或变体可用于预防和/或治疗炎性活动，特别是不期望的胃肠炎症活动，例如炎性肠病或肠易激综合征。
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公开(公告)号：US20080311080A1
公开(公告)日：2008-12-18
申请号：US12123052
申请日：2008-05-19
CPC分类号： C12R1/01 , A23C9/1234 , A23L33/135 , A23V2002/00 , A23Y2220/77 , A61K39/09 , A61K2039/52 , A61K2039/542 , C12N1/20 , Y10S435/822 , Y10S435/853 , A23V2200/3204 , A23V2200/324
摘要： A strain of Bifidobacterium isolated from resected and washed human gastrointestinal tract is significantly immunomodulatory following oral consumption in humans. The strain is useful in the prophylaxis and/or treatment of undesirable inflammatory activity, especially gastrointestinal inflammatory activity such as inflammatory bowel disease or irritable bowel syndrome. The inflammatory activity may also be due to cancer.
摘要翻译： 从切除和洗涤的人类胃肠道分离的双歧杆菌菌株在人类口服消费后是显着的免疫调节。 该菌株可用于预防和/或治疗不期望的炎性活动，特别是胃肠道炎症活动，如炎性肠病或肠易激综合征。 炎症活动也可能是由于癌症。
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公开(公告)号：US20100112003A1
公开(公告)日：2010-05-06
申请号：US12479364
申请日：2009-06-05
CPC分类号： C12R1/01 , A23C9/1234 , A23L33/135 , A23V2002/00 , A23Y2220/77 , A61K39/09 , A61K2039/52 , A61K2039/542 , C12N1/20 , Y10S435/822 , Y10S435/853 , A23V2200/3204 , A23V2200/324
摘要： A strain of Bifidobacterium isolated from resected and washed human gastrointestinal tract is significantly immunomodulatory following oral consumption in humans. The strain is useful in the prophylaxis and/or treatment of undesirable inflammatory activity, especially gastrointestinal inflammatory activity such as inflammatory bowel disease or irritable bowel syndrome. The inflammatory activity may also be due to cancer.
摘要翻译： 从切除和洗涤的人类胃肠道分离的双歧杆菌菌株在人类口服消费后是显着的免疫调节。 该菌株可用于预防和/或治疗不期望的炎性活动，特别是胃肠道炎症活动，如炎性肠病或肠易激综合征。 炎症活动也可能是由于癌症。
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15.发明申请Modulation of Tissue Fatty Acid Composition of a Host by Human Gut Bacteria 审中-公开通过人肠细菌调节宿主的组织脂肪酸组成公开(公告)号：US20100284979A1
公开(公告)日：2010-11-11
申请号：US12681045
申请日：2008-09-30
申请人： Liam O'Mahony , Fergus Shanahan , Eamonn Quigley , Paul Ross , Catherine Stanton
发明人： Liam O'Mahony , Fergus Shanahan , Eamonn Quigley , Paul Ross , Catherine Stanton
CPC分类号： C12N1/20 , A23L33/135 , A61K31/201 , A61K35/74 , A61K35/744 , A61K35/745 , A61K35/747 , C12P7/6427 , C12P7/6472 , C12R1/01
摘要： The current invention provides use of a CLA-producing bacterium for the in vivo conversion in the gut of polyunsaturated fatty acids to CLA. The CLA-producing bacterium is selected from one or more of the group consisting of propionibacteria, lactobacilli, lactococci and streptococci, and bifidobacteria.
摘要翻译： 本发明提供了使CLA产生细菌用于多不饱和脂肪酸肠内体内转化成CLA的用途。 产生CLA的细菌选自丙酸杆菌属，乳杆菌属，乳球菌属和链球菌属中的一种或多种，以及双歧杆菌。
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公开(公告)号：US07195906B2
公开(公告)日：2007-03-27
申请号：US10783020
申请日：2004-02-23
CPC分类号： C12R1/01 , A23C9/1234 , A23L33/135 , A23V2002/00 , A23Y2220/77 , A61K39/09 , A61K2039/52 , A61K2039/542 , C12N1/20 , Y10S435/822 , Y10S435/853 , A23V2200/3204 , A23V2200/324
摘要： A strain of Bifidobacterium isolated from resected and washed human gastrointestinal tract is significantly immunomodulatory following oral consumption in humans. The strain is useful in the prophylaxis and/or treatment of undesirable inflammatroy activity, especially gastrointestinal inflammatory activity such as inflammatory bowel disease or irritable bowel syndrome. The inflammatory activity may also be due to cancer.
摘要翻译： 从切除和洗涤的人类胃肠道分离的双歧杆菌菌株在人类口服消费后是显着的免疫调节。 该菌株可用于预防和/或治疗不期望的炎症活性，特别是胃肠炎症活动如炎性肠病或肠易激综合征。 炎症活动也可能是由于癌症。
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17.发明申请公开(公告)号：US20130217600A1
公开(公告)日：2013-08-22
申请号：US13524020
申请日：2012-06-15
申请人： Ker-Sang Chen , John Kevin Collins , Barry Pius Kiely , Fangyi Luo , Liam Diarmuid O'Mahony , Ross Peter Phillipson , Fergus Shanahan
发明人： Ker-Sang Chen , John Kevin Collins , Barry Pius Kiely , Fangyi Luo , Liam Diarmuid O'Mahony , Ross Peter Phillipson , Fergus Shanahan
IPC分类号： G01N33/68
CPC分类号： G01N33/6869 , G01N33/5008 , G01N33/5023 , G01N33/5044 , G01N33/5091 , G01N33/6863 , G01N33/6866 , G01N2333/52 , G01N2800/065 , G01N2800/52
摘要： Novel methods of determining efficacy of a treatment of inflammatory diseases of the bowel in mammals are provided. The methods are of use in screening and determining the efficacy of treatments of inflammatory diseases of the bowel, and for determining the efficacy response of individual sufferers of inflammatory diseases of the bowel to a given regime. Kits for carrying out the method are also provided.
摘要翻译： 提供了确定哺乳动物肠道炎性疾病治疗功效的新方法。 该方法可用于筛选和确定肠炎性疾病治疗的功效，并用于确定个体炎症性疾病患者对给定方案的疗效反应。 还提供了用于执行该方法的套件。
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公开(公告)号：US08216563B2
公开(公告)日：2012-07-10
申请号：US13036109
申请日：2011-02-28
申请人： Ker-Sang Chen , John Kevin Collins , Barry Pius Kiely , Fangyi Luo , Liam Diarmuid O'Mahony , Ross Peter Phillipson , Fergus Shanahan
发明人： Ker-Sang Chen , John Kevin Collins , Barry Pius Kiely , Fangyi Luo , Liam Diarmuid O'Mahony , Ross Peter Phillipson , Fergus Shanahan
CPC分类号： G01N33/6869 , G01N33/5008 , G01N33/5023 , G01N33/5044 , G01N33/5091 , G01N33/6863 , G01N33/6866 , G01N2333/52 , G01N2800/065 , G01N2800/52
摘要： Novel methods of determining efficacy of a treatment of inflammatory diseases of the bowel in mammals are provided. The methods are of use in screening and determining the efficacy of treatments of inflammatory diseases of the bowel, and for determining the efficacy response of individual sufferers of inflammatory diseases of the bowel to a given regime. Kits for carrying out the method are also provided.
摘要翻译： 提供了确定哺乳动物肠道炎性疾病治疗功效的新方法。 该方法可用于筛选和确定肠炎性疾病治疗的功效，并用于确定个体炎症性疾病患者对给定方案的疗效反应。 还提供了用于执行该方法的套件。
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19.发明授权公开(公告)号：US07923000B2
公开(公告)日：2011-04-12
申请号：US10810358
申请日：2004-03-26
申请人： Ker-Sang Chen , John Kevin Collins , Barry Pius Kiely , Fangyi Luo , Liam Diarmuid O'Mahony , Ross Peter Phillipson , Fergus Shanahan
发明人： Ker-Sang Chen , John Kevin Collins , Barry Pius Kiely , Fangyi Luo , Liam Diarmuid O'Mahony , Ross Peter Phillipson , Fergus Shanahan
CPC分类号： G01N33/6869 , G01N33/5008 , G01N33/5023 , G01N33/5044 , G01N33/5091 , G01N33/6863 , G01N33/6866 , G01N2333/52 , G01N2800/065 , G01N2800/52
摘要： Novel methods of determining efficacy of a treatment of inflammatory diseases of the bowel in mammals are provided. The methods are of use in screening and determining the efficacy of treatments of inflammatory diseases of the bowel, and for determining the efficacy response of individual sufferers of inflammatory diseases of the bowel to a given regime. Kits for carrying out the method are also provided.
摘要翻译： 提供了确定哺乳动物肠道炎性疾病治疗功效的新方法。 该方法可用于筛选和确定肠炎性疾病治疗的功效，并用于确定个体炎症性疾病患者对给定方案的疗效反应。 还提供了用于执行该方法的套件。
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公开(公告)号：US20110152117A1
公开(公告)日：2011-06-23
申请号：US13036109
申请日：2011-02-28
申请人： Ker-Sang Chen , John Kevin Collins , Barry Pius Kiely , Fangyi Luo , Liam Diarmuid O'Mahony , Ross Peter Phillipson , Fergus Shanahan
发明人： Ker-Sang Chen , John Kevin Collins , Barry Pius Kiely , Fangyi Luo , Liam Diarmuid O'Mahony , Ross Peter Phillipson , Fergus Shanahan
CPC分类号： G01N33/6869 , G01N33/5008 , G01N33/5023 , G01N33/5044 , G01N33/5091 , G01N33/6863 , G01N33/6866 , G01N2333/52 , G01N2800/065 , G01N2800/52
摘要： Novel methods of determining efficacy of a treatment of inflammatory diseases of the bowel in mammals are provided. The methods are of use in screening and determining the efficacy of treatments of inflammatory diseases of the bowel, and for determining the efficacy response of individual sufferers of inflammatory diseases of the bowel to a given regime. Kits for carrying out the method are also provided.
摘要翻译： 提供了确定哺乳动物肠道炎性疾病治疗功效的新方法。 该方法可用于筛选和确定肠炎性疾病治疗的功效，并用于确定个体炎症性疾病患者对给定方案的疗效反应。 还提供了用于执行该方法的套件。
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