摘要:
Microfluidic devices provide substances to a mass spectrometer. The microfluidic devices include first and second surfaces, at least one microchannel formed by the surfaces, and an outlet at an edge of the surfaces which is recessed back from an adjacent portion of the edge. Hydrophilic surfaces and/or hydrophobic surfaces guide substances out of the outlet. A source of electrical potential can help move substances through the microchannel, separate substances and/or provide electrospray ionization.
摘要:
In an example embodiment, a bundle loader is run in response to a communication from an application. The communication may indicate that the plurality of bundles of components in the application is to be executed. The plurality of bundles may include at least one bundle having a component that depends on a dependency component in another of the plurality of bundles. A configuration file indicating a set of the plurality of bundles to load in the bundle loader is received. The bundle loader is operated to load a bundle manifest for each bundle in the set of the plurality of bundles to load. Then, for each of the bundles in the set of plurality of bundles to load, the bundle is activated if no unactivated dependency component exists for any component in the bundle.
摘要:
The present disclosure involves systems, software, and computer implemented methods for operating on type instances. One example method includes identifying a reference to a type instance during execution of a child control flow. The child control flow is associated with one or more ancestor control flows. One or more stack frames associated with the ancestor control flows are searched for a prior instantiation of the type instance. Access to the prior instantiation of the type instance in an identified stack frame associated with an identified ancestor control flow is provided in response to determining that the prior instantiation of the type instance exists in the identified stack frame. A new instance of the type instance is instantiated in a stack frame associated with the child control flow in response to determining that the prior instantiation of the type instance does not exist in the one or more stack frames.
摘要:
Systems, methods and techniques relating to managing execution of applications in a runtime environment are described. A described technique includes identifying logic for executing an application code, identifying a first portion of the application code associated with the identified logic and executed by a first runtime container, identifying a second portion of the application code associated with the identified logic, determining, based on a policy or a characteristic associated with the application code, a second runtime container to execute the second portion of the application code, and dispatching a request and the identified logic to the second runtime container for executing the second portion of the application code.
摘要:
The present invention provides for compositions, kits and methods for treatment of intraepithelial neoplasia, where the compositions include catecholic butanes, which include NDGA derivatives.
摘要:
The present invention provides kits, methods and compositions for the treatment of obesity. The compositions herein contain a substantially pure preparation of at least one catecholic butane, including, for example, NDGA compounds in a pharmaceutically acceptable carrier or excipient. The catecholic butane such as NDGA or its derivatives are administered to one or more subjects in need of treatment.
摘要:
An automated electrospray ionization (ESI) device and related methods to optimize electrospray interface conditions for mass spectrometric analysis. The optimization process can be performed with calibration or optimization solutions that produce expected ESI parameters such as an ESI signal or an ion current. The ESI device may include an input/output (I/O) controller that is coupled to an electrospray assembly including an XYZ stage for positioning an electrospray emitter relative to a mass spectrometer orifice. The I/O controller may be connected to a power supply for applying an adjustable electrospray ionization voltage, and an adjustable flow regulator that alters the flow of solution by modifying applied voltage and/or pressure. A central processing unit instructs the I/O controller to control selectively the electrospray assembly based on the resultant signals from the mass spectrometer or the ion currents within the mass spectrometer in accordance with a predetermined optimization algorithm. The resulting ESI signal or ion currents are monitored and provide feedback to the I/O controller which can automatically instruct selected system components to make adjustments as needed to attain optimal settings that produce expected ESI signals or ion currents in the mass spectrometer for selected solutions.
摘要:
Usage patterns of structure model are utilized to determine a personalized structure model associated with a user. The personalized structure model is constructed such that retrieval of data associated with the personalized structure model is expected to improve performance of retrieving data from the data provider. The personalized structure model may be arranged based on an order of retrieval, based on groups of structure objects that may be retrieved together or the like. The personalized structure model may be a flat structure model to further improve performance of retrieving data from the data provider.
摘要:
The present disclosure involves systems, software, and computer implemented methods for operating on type instances. One example method includes identifying a reference to a type instance during execution of a child control flow. The child control flow is associated with one or more ancestor control flows. One or more stack frames associated with the ancestor control flows are searched for a prior instantiation of the type instance. Access to the prior instantiation of the type instance in an identified stack frame associated with an identified ancestor control flow is provided in response to determining that the prior instantiation of the type instance exists in the identified stack frame. A new instance of the type instance is instantiated in a stack frame associated with the child control flow in response to determining that the prior instantiation of the type instance does not exist in the one or more stack frames.
摘要:
The present invention relates to managing a multi-directional advertising value chain and effectively managing a very large number of partnerships where each partner can, over time, fulfill any and all of the piece of that value chain simultaneously. According to the present invention, tracking, accounting, controlling and netting out of compensation for the various pieces of the is flexible enough to dynamically adjust any piece of the advertising value chain as business relationships evolve.