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公开(公告)号:US10155074B2
公开(公告)日:2018-12-18
申请号:US14811355
申请日:2015-07-28
Applicant: KCI Licensing, Inc.
Inventor: Larry D. Swain , Michael E. Manwaring , Douglas A. Cornet , Braden King-fung Leung
Abstract: An apparatus and system for treating a wound having a cavity is disclosed. The apparatus has a scaffold including a scaffold lamina and a tissue lamina wherein the scaffold lamina forms a laminate in fluid communication with the tissue lamina. The laminate is rolled into a generally cylindrical shape having two end surfaces. The apparatus further includes a manifold having a port for coupling to a source of reduced pressure and that is positioned in fluid communication with the scaffold to provide reduced pressure to the scaffold lamina and the wound. A method for treating a wound having a cavity is also disclosed and includes positioning a scaffold lamina adjacent a tissue lamina to form a laminate in fluid communication with the tissue lamina, rolling the laminate into a generally cylindrical shape having two end surfaces, and positioning the scaffold within the cavity of the wound.
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12.
公开(公告)号:US09023113B2
公开(公告)日:2015-05-05
申请号:US14098195
申请日:2013-12-05
Applicant: KCI Licensing, Inc.
Inventor: Larry D. Swain , Michael E. Manwaring , Douglas A. Cornet , Braden K. Leung
CPC classification number: A61F2/28 , A61F2002/2817 , A61F2002/4685 , A61L27/54 , A61M1/0031 , A61M1/0035 , A61M1/0088 , A61M5/16881 , A61M27/00 , A61M39/22 , A61M2205/3334
Abstract: Provided are apparatuses, systems, and methods for treating tissue at a tissue site in a mammal that includes a scaffold adapted to be disposed adjacent to the tissue site and to be fluidly coupled to a blood vessel of the mammal for receiving blood therefrom. Additionally, a scaffold is provided that includes a charged surface comprising a streaming potential.
Abstract translation: 提供了用于在哺乳动物的组织部位处理组织的装置,系统和方法,所述装置,系统和方法包括适于邻近所述组织部位设置并与所述哺乳动物的血管流体耦合以从其接收血液的支架。 另外,提供了一种支架,其包括包含流动电位的带电表面。
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公开(公告)号:US20140276251A1
公开(公告)日:2014-09-18
申请号:US14252644
申请日:2014-04-14
Applicant: KCI Licensing, Inc.
Inventor: Larry D. Swain , Michael E. Manwaring , Douglas A. Cornet , Braden King-Fung Leung
CPC classification number: A61F13/00068 , A61B17/88 , A61F2/2846 , A61F13/00063 , A61F2002/2835 , A61F2002/30784 , A61F2002/368 , A61F2013/00357 , A61F2013/00927 , A61K38/18 , A61K38/19 , A61K38/22 , A61K49/223 , A61M1/0023 , A61M1/0088 , A61M27/00 , A61M37/00 , A61M37/0092 , A61N5/062
Abstract: Provided is an apparatus that includes a scaffold with a gel or liquid composition deposed on at least a portion of a luminal surface, the gel or liquid composition adapted to include microbubbles. Also provided is a system that includes a source of reduced pressure, the above scaffold, a manifold adjacent the scaffold, and a conduit for providing fluid communication between the manifold and the source of reduced pressure. Additionally provided is a method that includes implanting the above scaffold at the tissue site and disrupting a substantial portion of the microbubbles to induce fluid flow to the scaffold. Further provided is an apparatus that includes a scaffold that comprises a slowly degradable material and a quickly degradable material. Additionally provided is a system for coupling nerve tissue and a microchip assembly.
Abstract translation: 提供了一种装置,其包括具有凝胶或液体组合物的支架,所述支架沉积在腔表面的至少一部分上,所述凝胶或液体组合物适于包含微泡。 还提供了一种包括减压源的系统,上述支架,邻近支架的歧管和用于在歧管和减压源之间提供流体连通的导管。 另外提供了一种方法,其包括将上述支架植入组织部位并破坏大部分微泡以诱导流体流入支架。 还提供了一种装置,其包括包含缓慢降解材料和快速可降解材料的支架。 另外提供了一种用于联接神经组织和微芯片组件的系统。
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公开(公告)号:US20130237934A1
公开(公告)日:2013-09-12
申请号:US13870059
申请日:2013-04-25
Applicant: KCI LICENSING, INC.
Inventor: Larry Swain , Michael Manwaring , Braden K. Leung , Douglas A. Cornet
IPC: A61F13/00
CPC classification number: A61M1/0088 , A61B17/11 , A61B17/1128 , A61F13/00063 , A61F13/00068
Abstract: Provided is an apparatus that includes a nerve conduit, a manifold and a support structure for providing a reduced pressure. Also provided is a system that includes a source of reduced pressure, a nerve conduit, a manifold, a support structure and a conduit for providing fluid communication between the manifold support and the source of reduced pressure. Additionally provided is a method that includes implanting the above nerve conduit, manifold and support structure at a site of damaged nerve tissue and applying a reduced pressure to the manifold thereby stimulataing repair or regrowth of nerve tissue.
Abstract translation: 提供了一种包括神经管道,歧管和用于提供减压的支撑结构的装置。 还提供了一种包括减压源的系统,神经管道,歧管,支撑结构和用于在歧管支撑件和减压源之间提供流体连通的导管。 另外提供了一种方法,其包括在损伤的神经组织的位置植入上述神经导管,歧管和支撑结构,并将减压施加到歧管,从而刺激神经组织的修复或再生长。
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15.
公开(公告)号:US11311662B2
公开(公告)日:2022-04-26
申请号:US16352630
申请日:2019-03-13
Applicant: KCI Licensing, Inc.
Inventor: Justin Alexander Long , Michael E. Manwaring , Douglas A. Cornet
Abstract: The illustrative embodiments described herein are directed to systems, methods, and apparatuses for applying a reduced pressure to a subcutaneous tissue site. In one instance, a manifold for applying reduced pressure to a subcutaneous tissue site includes a plurality of first conduits, each of the plurality of first conduits having a wall with at least one first aperture and at least one second aperture. At least one of the plurality of first conduits is operable to deliver reduced pressure to the subcutaneous tissue site. The plurality of first conduits is coupled in a spaced arrangement that forms an interior space. The manifold further includes a second conduit comprising the interior space and formed by a portion of each wall of the plurality of first conduits. The second conduit is in fluid communication with the plurality of first conduits via the at least one second aperture.
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16.
公开(公告)号:US10258722B2
公开(公告)日:2019-04-16
申请号:US14489173
申请日:2014-09-17
Applicant: KCI Licensing, Inc.
Inventor: Justin Alexander Long , Michael E. Manwaring , Douglas A. Cornet
Abstract: The illustrative embodiments described herein are directed to systems, methods, and apparatuses for applying a reduced pressure to a subcutaneous tissue site. In one instance, a manifold for applying reduced pressure to a subcutaneous tissue site includes a plurality of first conduits, each of the plurality of first conduits having a wall with at least one first aperture and at least one second aperture. At least one of the plurality of first conduits is operable to deliver reduced pressure to the subcutaneous tissue site. The plurality of first conduits is coupled in a spaced arrangement that forms an interior space. The manifold further includes a second conduit comprising the interior space and formed by a portion of each wall of the plurality of first conduits. The second conduit is in fluid communication with the plurality of first conduits via the at least one second aperture.
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公开(公告)号:US10137228B2
公开(公告)日:2018-11-27
申请号:US15174451
申请日:2016-06-06
Applicant: KCI Licensing, Inc.
Inventor: Douglas A. Cornet , Michael E. Manwaring
Abstract: An apparatus, system, and method for treating an incisional wound having incisional walls is disclosed. The apparatus includes a conduit having a first end for receiving reduced pressure and a second end. The apparatus further includes a scaffold. The scaffold has opposing surfaces for positioning adjacent the incisional walls and is fluidly coupled to the second end of the conduit for receiving the reduced pressure. The scaffold is generally elongated in shape and has a thickness between the opposing surfaces that is sufficiently thin for positioning within the incisional wound. The apparatus further includes an internal manifold that has a primary flow channel extending generally longitudinally within the scaffold and between the opposing surfaces of the scaffold. The internal manifold is fluidly coupled to the second end of the conduit. The application of the reduced pressure through the scaffold and the internal manifold induces tissue apposition between the incisional walls.
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公开(公告)号:US09918880B2
公开(公告)日:2018-03-20
申请号:US14252644
申请日:2014-04-14
Applicant: KCI Licensing, Inc.
Inventor: Larry D. Swain , Michael E. Manwaring , Douglas A. Cornet , Braden King-Fung Leung
IPC: A61M1/00 , A61M27/00 , A61F13/00 , A61K38/18 , A61K38/19 , A61K38/22 , A61M37/00 , A61N5/06 , A61M31/00 , A61M3/00 , A61F13/20 , A61F5/44 , A61F2/28 , A61F2/30 , A61B17/88 , A61F2/36 , A61K49/22
CPC classification number: A61F13/00068 , A61B17/88 , A61F2/2846 , A61F13/00063 , A61F2002/2835 , A61F2002/30784 , A61F2002/368 , A61F2013/00357 , A61F2013/00927 , A61K38/18 , A61K38/19 , A61K38/22 , A61K49/223 , A61M1/0023 , A61M1/0088 , A61M27/00 , A61M37/00 , A61M37/0092 , A61N5/062
Abstract: Provided is an apparatus that includes a scaffold with a gel or liquid composition deposed on at least a portion of a luminal surface, the gel or liquid composition adapted to include microbubbles. Also provided is a system that includes a source of reduced pressure, the above scaffold, a manifold adjacent the scaffold, and a conduit for providing fluid communication between the manifold and the source of reduced pressure. Additionally provided is a method that includes implanting the above scaffold at the tissue site and disrupting a substantial portion of the microbubbles to induce fluid flow to the scaffold. Further provided is an apparatus that includes a scaffold that comprises a slowly degradable material and a quickly degradable material. Additionally provided is a system for coupling nerve tissue and a microchip assembly.
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公开(公告)号:US08992552B2
公开(公告)日:2015-03-31
申请号:US13870059
申请日:2013-04-25
Applicant: KCI Licensing, Inc.
Inventor: Larry Swain , Michael Manwaring , Braden K. Leung , Douglas A. Cornet
CPC classification number: A61M1/0088 , A61B17/11 , A61B17/1128 , A61F13/00063 , A61F13/00068
Abstract: Provided is an apparatus that includes a nerve conduit, a manifold and a support structure for providing a reduced pressure. Also provided is a system that includes a source of reduced pressure, a nerve conduit, a manifold, a support structure and a conduit for providing fluid communication between the manifold support and the source of reduced pressure. Additionally provided is a method that includes implanting the above nerve conduit, manifold and support structure at a site of damaged nerve tissue and applying a reduced pressure to the manifold thereby stimulating repair or regrowth of nerve tissue.
Abstract translation: 提供了一种包括神经管道,歧管和用于提供减压的支撑结构的装置。 还提供了一种包括减压源的系统,神经管道,歧管,支撑结构和用于在歧管支撑件和减压源之间提供流体连通的导管。 另外提供了一种方法,其包括在损伤的神经组织的位置处植入上述神经导管,歧管和支撑结构,并将减压施加到歧管,从而刺激神经组织的修复或再生长。
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20.
公开(公告)号:US10369269B2
公开(公告)日:2019-08-06
申请号:US14569436
申请日:2014-12-12
Applicant: KCI Licensing, Inc.
Inventor: Carl Joseph Santora , Michael E. Manwaring , Douglas A. Cornet , Justin Alexander Long , Larry D. Swain
IPC: A61M1/00 , A61M25/00 , A61M27/00 , A61M3/02 , A61B17/88 , A61F2/36 , A61F2/30 , A61B17/135 , A61B17/80
Abstract: Systems, methods, and apparatuses are provided for delivering reduced pressure to a subcutaneous tissue site, such as a bone tissue site. In one instance, a manifold for providing reduced pressure to a subcutaneous tissue includes a longitudinal manifold body formed with at least one purging lumen and a reduced-pressure lumen. The manifold further includes a plurality of manifolding surface features or slits formed on the second, tissue-facing side of the longitudinal manifold body and a plurality of apertures formed in the longitudinal manifold body on the second, tissue-facing side. The plurality of apertures fluidly couple the reduced-pressure lumen and the manifolding surface features or slits. The manifold further includes an end cap fluidly coupling the reduced-pressure lumen and the at least one purging lumen. Other systems, apparatuses, and methods are presented.
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