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公开(公告)号:US11357904B2
公开(公告)日:2022-06-14
申请号:US16671460
申请日:2019-11-01
Applicant: KCI Licensing, Inc.
Inventor: Larry D. Swain , Michael E. Manwaring , Braden King-fung Leung , Douglas A. Cornet
Abstract: An apparatus and system for providing reduced pressure to a defect in a nerve is disclosed. The apparatus comprises a nerve conduit having a generally tubular shape that has walls including a luminal wall surrounding the tissue site to contain fluids within a luminal space between the tissue site to contain fluids within a luminal space between the tissue site and the luminal wall. The apparatus further comprises a manifold having a porous body and a connector for receiving reduced pressure, wherein the manifold is positioned within the luminal space adjacent the tissue site to distribute the reduced pressure to the defect. Additionally, a method for providing reduced pressure to a defect in a nerve is disclosed that includes implanting the nerve conduit and manifold at a site of damaged nerve tissue and applying a reduced pressure to the manifold thereby stimulating repair or regrowth of nerve tissue.
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公开(公告)号:US10946125B2
公开(公告)日:2021-03-16
申请号:US16171069
申请日:2018-10-25
Applicant: KCI Licensing, Inc.
Inventor: Michael E. Manwaring , Douglas A. Cornet
Abstract: An apparatus, system, and method for treating an incisional wound having incisional walls. The apparatus includes a conduit having a first end for receiving reduced pressure and a second end. The apparatus further includes a scaffold. The scaffold has opposing surfaces for positioning adjacent the incisional walls and is fluidly coupled to the second end of the conduit for receiving the reduced pressure. The scaffold is generally elongated in shape and has a thickness between the opposing surfaces that is sufficiently thin for positioning within the incisional wound. The apparatus further includes an internal manifold that has a primary flow channel extending generally longitudinally within the scaffold and between the opposing surfaces of the scaffold. The internal manifold is fluidly coupled to the second end of the conduit. The application of the reduced pressure through the scaffold and the internal manifold induces tissue apposition between the incisional walls.
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公开(公告)号:US09918733B2
公开(公告)日:2018-03-20
申请号:US14708109
申请日:2015-05-08
Applicant: KCI Licensing, Inc.
Inventor: Shannon C. Ingram , Christopher Brian Locke , Peter Arnold , Timothy Mark Robinson , Christopher A. Carroll , Michael E. Manwaring
CPC classification number: A61B17/32 , A61B17/22004 , A61B2017/22008 , A61B2017/22089 , A61B2017/320008 , A61B2017/32006 , A61B2017/320064 , A61F13/00068 , A61M1/0084 , A61M1/0088 , A61M27/00
Abstract: A method and apparatus for disrupting material at a tissue site is described. A contact layer may be selected for use on the tissue site and positioned adjacent to the tissue site. The contact layer may include walls defining a plurality of through-holes. A sealing member may be positioned over the contact layer and sealed to tissue surrounding the tissue site to form a sealed space enclosing the contact layer. A negative-pressure source may be fluidly coupled to the sealed space. The negative-pressure source may supply negative pressure to the sealed space and the contact layer to draw tissue into the through-holes to form nodules. The negative pressure may be vented from the sealed space to release the nodules.
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公开(公告)号:US09381284B2
公开(公告)日:2016-07-05
申请号:US14088027
申请日:2013-11-22
Applicant: KCI Licensing, Inc.
Inventor: Douglas A. Cornet , Michael E. Manwaring
CPC classification number: A61M1/0088 , A61B17/08 , A61B17/085 , A61B2017/00004 , A61B2017/00893 , A61B2017/081 , A61B2017/306 , A61B2090/065 , A61F13/00068 , A61F2013/00221 , A61F2013/00455 , A61F2013/00536 , A61F2013/0054 , A61M1/0084
Abstract: An apparatus, system, and method for treating an incisional wound having incisional walls is disclosed. The apparatus includes a conduit having a first end for receiving reduced pressure and a second end. The apparatus further includes a scaffold. The scaffold has opposing surfaces for positioning adjacent the incisional walls and is fluidly coupled to the second end of the conduit for receiving the reduced pressure. The scaffold is generally elongated in shape and has a thickness between the opposing surfaces that is sufficiently thin for positioning within the incisional wound. The apparatus further includes an internal manifold that has a primary flow channel extending generally longitudinally within the scaffold and between the opposing surfaces of the scaffold. The internal manifold is fluidly coupled to the second end of the conduit. The application of the reduced pressure through the scaffold and the internal manifold induces tissue apposition between the incisional walls.
Abstract translation: 公开了一种用于治疗具有切口壁的切口伤口的装置,系统和方法。 该设备包括具有用于接收减压的第一端和第二端的导管。 该装置还包括支架。 支架具有用于邻近切口壁定位的相对表面,并且流体地联接到管道的第二端以接收减压。 支架通常为细长形状,并且在相对表面之间具有足够薄的厚度,用于定位在切口伤口内。 该装置还包括内部歧管,其具有在支架内大体上纵向延伸并且在支架的相对表面之间延伸的主流动通道。 内部歧管流体地联接到导管的第二端。 减压通过支架和内部歧管的应用导致切口壁之间的组织结合。
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公开(公告)号:US20140094928A1
公开(公告)日:2014-04-03
申请号:US14098195
申请日:2013-12-05
Applicant: KCI Licensing, Inc.
Inventor: Larry D. Swain , Michael E. Manwaring , Douglas A. Cornet , Braden K. Leung
CPC classification number: A61F2/28 , A61F2002/2817 , A61F2002/4685 , A61L27/54 , A61M1/0031 , A61M1/0035 , A61M1/0088 , A61M5/16881 , A61M27/00 , A61M39/22 , A61M2205/3334
Abstract: Provided are apparatuses, systems, and methods for treating tissue at a tissue site in a mammal that includes a scaffold adapted to be disposed adjacent to the tissue site and to be fluidly coupled to a blood vessel of the mammal for receiving blood therefrom. Additionally, a scaffold is provided that includes a charged surface comprising a streaming potential.
Abstract translation: 提供了用于在哺乳动物的组织部位处理组织的装置,系统和方法,所述装置,系统和方法包括适于邻近所述组织部位设置并与所述哺乳动物的血管流体耦合以从其接收血液的支架。 另外,提供了一种支架,其包括包含流动电位的带电表面。
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公开(公告)号:US11311662B2
公开(公告)日:2022-04-26
申请号:US16352630
申请日:2019-03-13
Applicant: KCI Licensing, Inc.
Inventor: Justin Alexander Long , Michael E. Manwaring , Douglas A. Cornet
Abstract: The illustrative embodiments described herein are directed to systems, methods, and apparatuses for applying a reduced pressure to a subcutaneous tissue site. In one instance, a manifold for applying reduced pressure to a subcutaneous tissue site includes a plurality of first conduits, each of the plurality of first conduits having a wall with at least one first aperture and at least one second aperture. At least one of the plurality of first conduits is operable to deliver reduced pressure to the subcutaneous tissue site. The plurality of first conduits is coupled in a spaced arrangement that forms an interior space. The manifold further includes a second conduit comprising the interior space and formed by a portion of each wall of the plurality of first conduits. The second conduit is in fluid communication with the plurality of first conduits via the at least one second aperture.
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公开(公告)号:US10258722B2
公开(公告)日:2019-04-16
申请号:US14489173
申请日:2014-09-17
Applicant: KCI Licensing, Inc.
Inventor: Justin Alexander Long , Michael E. Manwaring , Douglas A. Cornet
Abstract: The illustrative embodiments described herein are directed to systems, methods, and apparatuses for applying a reduced pressure to a subcutaneous tissue site. In one instance, a manifold for applying reduced pressure to a subcutaneous tissue site includes a plurality of first conduits, each of the plurality of first conduits having a wall with at least one first aperture and at least one second aperture. At least one of the plurality of first conduits is operable to deliver reduced pressure to the subcutaneous tissue site. The plurality of first conduits is coupled in a spaced arrangement that forms an interior space. The manifold further includes a second conduit comprising the interior space and formed by a portion of each wall of the plurality of first conduits. The second conduit is in fluid communication with the plurality of first conduits via the at least one second aperture.
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公开(公告)号:US10137228B2
公开(公告)日:2018-11-27
申请号:US15174451
申请日:2016-06-06
Applicant: KCI Licensing, Inc.
Inventor: Douglas A. Cornet , Michael E. Manwaring
Abstract: An apparatus, system, and method for treating an incisional wound having incisional walls is disclosed. The apparatus includes a conduit having a first end for receiving reduced pressure and a second end. The apparatus further includes a scaffold. The scaffold has opposing surfaces for positioning adjacent the incisional walls and is fluidly coupled to the second end of the conduit for receiving the reduced pressure. The scaffold is generally elongated in shape and has a thickness between the opposing surfaces that is sufficiently thin for positioning within the incisional wound. The apparatus further includes an internal manifold that has a primary flow channel extending generally longitudinally within the scaffold and between the opposing surfaces of the scaffold. The internal manifold is fluidly coupled to the second end of the conduit. The application of the reduced pressure through the scaffold and the internal manifold induces tissue apposition between the incisional walls.
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公开(公告)号:US09918880B2
公开(公告)日:2018-03-20
申请号:US14252644
申请日:2014-04-14
Applicant: KCI Licensing, Inc.
Inventor: Larry D. Swain , Michael E. Manwaring , Douglas A. Cornet , Braden King-Fung Leung
IPC: A61M1/00 , A61M27/00 , A61F13/00 , A61K38/18 , A61K38/19 , A61K38/22 , A61M37/00 , A61N5/06 , A61M31/00 , A61M3/00 , A61F13/20 , A61F5/44 , A61F2/28 , A61F2/30 , A61B17/88 , A61F2/36 , A61K49/22
CPC classification number: A61F13/00068 , A61B17/88 , A61F2/2846 , A61F13/00063 , A61F2002/2835 , A61F2002/30784 , A61F2002/368 , A61F2013/00357 , A61F2013/00927 , A61K38/18 , A61K38/19 , A61K38/22 , A61K49/223 , A61M1/0023 , A61M1/0088 , A61M27/00 , A61M37/00 , A61M37/0092 , A61N5/062
Abstract: Provided is an apparatus that includes a scaffold with a gel or liquid composition deposed on at least a portion of a luminal surface, the gel or liquid composition adapted to include microbubbles. Also provided is a system that includes a source of reduced pressure, the above scaffold, a manifold adjacent the scaffold, and a conduit for providing fluid communication between the manifold and the source of reduced pressure. Additionally provided is a method that includes implanting the above scaffold at the tissue site and disrupting a substantial portion of the microbubbles to induce fluid flow to the scaffold. Further provided is an apparatus that includes a scaffold that comprises a slowly degradable material and a quickly degradable material. Additionally provided is a system for coupling nerve tissue and a microchip assembly.
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公开(公告)号:US10743900B2
公开(公告)日:2020-08-18
申请号:US15884149
申请日:2018-01-30
Applicant: KCI Licensing, Inc.
Inventor: Shannon C. Ingram , Christopher Brian Locke , Peter Arnold , Timothy Mark Robinson , Christopher A. Carroll , Michael E. Manwaring
Abstract: A method and apparatus for disrupting material at a tissue site is described. A contact layer may be selected for use on the tissue site and positioned adjacent to the tissue site. The contact layer may include walls defining a plurality of through-holes. A sealing member may be positioned over the contact layer and sealed to tissue surrounding the tissue site to form a sealed space enclosing the contact layer. A negative-pressure source may be fluidly coupled to the sealed space. The negative-pressure source may supply negative pressure to the sealed space and the contact layer to draw tissue into the through-holes to form nodules. The negative pressure may be vented from the sealed space to release the nodules.
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