公开(公告)号：US08390924B2

公开(公告)日：2013-03-05

申请号：US13237197

申请日：2011-09-20

Applicant: Daisuke Akiyama ,  Takeshi Suga ,  Satoshi Takekoshi ,  Kazuhiro Gono

Inventor： Daisuke Akiyama ,  Takeshi Suga ,  Satoshi Takekoshi ,  Kazuhiro Gono

IPC: G02B21/06 ,  G02B23/26

CPC classification number: A61B1/0646 ,  A61B1/00096 ,  A61B1/00186 ,  G02B23/2423

Abstract: An endoscope includes: a first illumination optical system which emits illuminating light in a first linear polarization direction to an object from a distal end face of an insertion portion; and a first objective optical system which allows return light from the object to enter through an objective window provided in the distal end face; wherein the first illumination optical system and the first objective optical system are placed in a positional relationship such that on the distal end face, a line segment connecting an optical axis of the first illumination optical system and an optical axis of the first objective optical system is parallel or perpendicular to a polarization direction which results when the illuminating light emitted from the first illumination optical system is projected to the distal end face, and no polarizing element is provided between the object and the objective window.

Abstract translation: 内窥镜包括：第一照明光学系统，其从插入部的远端面向物体照射第一线偏振方向的照明光; 以及第一物镜光学系统，其允许来自物体的返回光通过设置在远端面中的物镜窗进入; 其特征在于，所述第一照明光学系统和所述第一物镜光学系统的位置关系使得在所述前端面上连接所述第一照明光学系统的光轴和所述第一物镜光学系统的光轴的线段为 平行或垂直于当从第一照明光学系统发射的照明光被投射到远端面时产生的偏振方向，并且在物体和物镜窗之间不设置偏振元件。

公开(公告)号：US20090124853A1

公开(公告)日：2009-05-14

申请号：US11937185

申请日：2007-11-08

Applicant: Kazuhiro Gono ,  Takeshi Suga

Inventor： Kazuhiro Gono ,  Takeshi Suga

IPC: A61B1/04 ,  G12B13/00

CPC classification number: A61B1/041 ,  A61B1/00057 ,  A61B1/00147 ,  A61B1/042 ,  A61B5/06 ,  A61B5/065 ,  A61B5/073 ,  A61B2560/0223

Abstract: A capsule for determining the blood content of living tissue in vivo in a patient to detect tumors. The capsule includes a light source and a light detector for directing light onto the tissue and for receiving interacted light therefrom. By analyzing the interacted lights a determination can be made of the blood content of that tissue. There are various ways of positioning the capsule so that it contacts the tissue in the desired orientation of the light source and light detector. There is also a system for determining the actual contact between the capsule and the tissue. A calibration system is also used that allows a self calibration that can be carried out easily and accurately just prior to the use of the capsule.

Abstract translation: 一种胶囊，用于确定患者体内活体组织的血液含量以检测肿瘤。 胶囊包括光源和用于将光引导到组织上并用于从其接收相互作用的光的光检测器。 通过分析相互作用的光，可以确定该组织的血液含量。 存在定影胶囊的各种方式，使得其以光源和光检测器的期望定向接触组织。 还有一种用于确定胶囊和组织之间的实际接触的系统。 还使用校准系统，其允许在使用胶囊之前容易且准确地进行自校准。

公开(公告)号：US20090123043A1

公开(公告)日：2009-05-14

申请号：US11937153

申请日：2007-11-08

Applicant: Kazuhiro Gono ,  Takeshi Suga

Inventor： Kazuhiro Gono ,  Takeshi Suga

IPC: A61B5/00

CPC classification number: A61B5/073 ,  A61B1/041 ,  A61B1/2736 ,  A61B1/31 ,  A61B5/14539 ,  A61B5/14546

Abstract: Capsule type endoscopes generate large amounts of in-vivo image data that requires review and analysis by a doctor or clinician. By not reviewing the images gathered from healthy tissue, and only focusing on images indicating potential abnormalities, the time it takes to review the data can be greatly reduced. By correlating the tissue images with a characteristic known to indicate a potential abnormality, only the suspect images need to be reviewed.

Abstract translation: 胶囊型内窥镜产生大量的体内图像数据，需要医生或临床医生进行检查和分析。 通过不检查从健康组织收集的图像，只关注指示潜在异常的图像，可以大大减少检查数据所需的时间。 通过将组织图像与已知表示潜在异常的特征相关联，仅需要检查可疑图像。

公开(公告)号：US20090088601A1

公开(公告)日：2009-04-02

申请号：US12277898

申请日：2008-11-25

Applicant: Nobuyuki Doguchi ,  Hironobu Ichimura ,  Hideyasu Takato ,  Azusa Noguchi ,  Kazuhiro Gono ,  Kiyoshi Miyake

Inventor： Nobuyuki Doguchi ,  Hironobu Ichimura ,  Hideyasu Takato ,  Azusa Noguchi ,  Kazuhiro Gono ,  Kiyoshi Miyake

IPC: A61B1/00

CPC classification number: A61B1/0125 ,  A61B1/015 ,  A61B2090/3912 ,  A61B2090/395 ,  G02B23/2423

Abstract: An endoscope has an insertion portion, a contact portion, an observation portion and a marking portion. The insertion portion can be inserted into a body cavity. The contact portion is provided at a distal end portion of the insertion portion. The contact portion provided at the distal end portion can be in contact with a subject. The observation portion is provided at the contact portion. The marking portion is provided at the contact portion. The marking portion applies a marker to the subject with which the contact portion is in contact.

Abstract translation: 内窥镜具有插入部，接触部，观察部和标记部。 插入部分可插入体腔。 接触部设置在插入部的前端部。 设置在前端部的接触部可以与被检体接触。 观察部设置在接触部。 标记部分设置在接触部分处。 标记部分将标记施加到与接触部分接触的对象。

公开(公告)号：US20090082626A1

公开(公告)日：2009-03-26

申请号：US12323065

申请日：2008-11-25

Applicant: Hironobu Ichimura ,  Hideyasu Takato ,  Azusa Noguchi ,  Kiyoshi Miyake ,  Nobuyuki Doguchi ,  Kazuhiro Gono

Inventor： Hironobu Ichimura ,  Hideyasu Takato ,  Azusa Noguchi ,  Kiyoshi Miyake ,  Nobuyuki Doguchi ,  Kazuhiro Gono

IPC: A61B1/00 ,  A61B1/04

CPC classification number: G02B23/2438 ,  A61B1/00082 ,  A61B1/0125 ,  A61B5/6886 ,  G02B23/2446 ,  G02B23/2484

Abstract: An endoscope has an insertion portion, an abutment portion, an increasing device and an observation portion. The insertion portion is an insertion portion which can be inserted into a subject. The abutment portion is provided at a distal end portion of the insertion portion. The abutment portion provided at the distal end portion can contact with the subject. The increasing device increases the abutment area of the abutment portion. The observation portion performs observation of the subject on the abutment portion provided at the distal end portion and having been increased by the increasing device, or performs observation of the subject spaced by a predetermined distance by the increased abutment portion.

Abstract translation: 内窥镜具有插入部，抵接部，增大装置和观察部。 插入部是能够插入到被检体内的插入部。 该抵接部设置在插入部的前端部。 设置在前端部的抵接部可以与被检体接触。 增加的装置增加邻接部分的邻接面积。 观察部在被设置在前端部的抵接部上进行被检体的观察，并且通过增大装置增加，或者通过增大的邻接部进行间隔了规定距离的被检体。

公开(公告)号：US20080294105A1

公开(公告)日：2008-11-27

申请号：US12169185

申请日：2008-07-08

Applicant: Kazuhiro Gono ,  Tetsuo Nonami

Inventor： Kazuhiro Gono ,  Tetsuo Nonami

IPC: A61B1/045

CPC classification number: A61B1/0669 ,  A61B1/043 ,  A61B1/063 ,  A61B1/0638 ,  A61B1/0646 ,  A61B5/0071 ,  A61B5/0084

Abstract: An endoscope device obtains tissue information of a desired depth near the tissue surface. A xenon lamp (11) in a light source (4) emits illumination light. A diaphragm (13) controls a quantity of the light that reaches a rotating filter. The rotating filter has an outer sector with a first filter set, and an inner sector with a second filter set. The first filter set outputs frame sequence light having overlapping spectral properties suitable for color reproduction, while the second filter set outputs narrow-band frame sequence light having discrete spectral properties enabling extraction of desired deep tissue information. A condenser lens (16) collects the frame sequence light coming through the rotating filter onto the incident face of a light guide (15). The diaphragm controls the amount of the light reaching the filter depending on which filter set is selected.

Abstract translation: 内窥镜装置获取组织表面附近的期望深度的组织信息。 光源（4）中的氙灯（11）发射照明光。 光圈（13）控制到达旋转滤光器的光量。 旋转滤波器具有带有第一滤波器组的外部扇区和具有第二滤波器组的内部扇区。 第一滤波器组输出具有适于颜色再现的重叠光谱特性的帧序列光，而第二滤波器组输出具有能够提取期望的深层组织信息的离散光谱特性的窄带帧序列光。 聚光透镜（16）将通过旋转滤光器的框架序列光收集到光导（15）的入射面上。 根据所选择的滤波器组，光圈控制到达滤光器的光量。

公开(公告)号：US07172553B2

公开(公告)日：2007-02-06

申请号：US10146389

申请日：2002-05-14

Applicant: Hitoshi Ueno ,  Takeshi Ozawa ,  Kazunari Nakamura ,  Isami Hirao ,  Hiroshi Ibe ,  Koichi Yoshimitsu ,  Yuichi Morizane ,  Mamoru Kaneko ,  Shunya Akimoto ,  Masaki Terakubo ,  Katsuichi Imaizumi ,  Nobuyuki Doguchi ,  Sakae Takehana ,  Kazuhiro Gono

Inventor： Hitoshi Ueno ,  Takeshi Ozawa ,  Kazunari Nakamura ,  Isami Hirao ,  Hiroshi Ibe ,  Koichi Yoshimitsu ,  Yuichi Morizane ,  Mamoru Kaneko ,  Shunya Akimoto ,  Masaki Terakubo ,  Katsuichi Imaizumi ,  Nobuyuki Doguchi ,  Sakae Takehana ,  Kazuhiro Gono

IPC: A61B1/06 ,  A61B6/00

CPC classification number: A61B1/00059 ,  A61B1/00009 ,  A61B1/00186 ,  A61B1/043 ,  A61B1/045 ,  A61B1/0638 ,  A61B1/0646 ,  A61B1/0669 ,  A61B5/0071 ,  A61B5/0084

Abstract: In the light source unit 3A, a switching filter section 14, which can switch the RGB filter for normal-light observation and a filter for fluorescent observation on the optical path, is installed in front of the lamp 12, where if the fluorescent image mode is selected, the excitation light in a part of the blue wavelength band is supplied to the electronic endoscope 2A, and the excitation light reflected by the subject side is shielded by the excitation light cut filter 27 in front of the CCD 28 so as to obtain the fluorescent image, and also the signal of the fluorescent image and the signals of the two reflected light images which are set in a predetermined wavelength band are passed through the image processing circuit 38, where a matrix circuit for appropriately allocating the color signals of the R, G and B channels is installed, and as a result, the images can be displayed on the monitor 5 in pseudo-colors in hues which allow easy identification of a normal tissue and a pathologically affected tissue.

Abstract translation: 在光源单元3A中，在灯12的前方安装可以切换用于普通光观察的RGB滤光器的开关滤波器部分14和用于荧光观察的滤光器，其中如果荧光图像 选择蓝色波长带的一部分中的激发光被供给到电子内窥镜2A，并且由CCD 28反射的激励光被CCD28前方的激发光截止滤光器27遮蔽，从而 以获得荧光图像，并且将荧光图像的信号和设置在预定波长带中的两个反射光图像的信号通过图像处理电路38，其中用于适当地分配颜色信号的矩阵电路 安装了R，G和B通道，结果，图像可以以色调的伪色显示在监视器5上，这允许容易地识别正常组织和病态 在逻辑上影响组织。

公开(公告)号：US09017248B2

公开(公告)日：2015-04-28

申请号：US11937185

申请日：2007-11-08

Applicant: Kazuhiro Gono ,  Takeshi Suga

Inventor： Kazuhiro Gono ,  Takeshi Suga

IPC: A61B1/06 ,  A61B1/04 ,  A61B1/00 ,  A61B5/06 ,  A61B5/07

CPC classification number: A61B1/041 ,  A61B1/00057 ,  A61B1/00147 ,  A61B1/042 ,  A61B5/06 ,  A61B5/065 ,  A61B5/073 ,  A61B2560/0223

Abstract: A capsule for determining the blood content of living tissue in vivo in a patient to detect tumors. The capsule includes a light source and a light detector for directing light onto the tissue and for receiving interacted light therefrom. By analyzing the interacted light, a determination can be made of the blood content of that tissue. There are various ways of positioning the capsule so that it contacts the tissue in the desired orientation of the light source and light detector. There is also a system for determining the actual contact between the capsule and the tissue. A calibration system is also used that allows a self calibration that can be carried out easily and accurately just prior to the use of the capsule.

Abstract translation: 一种胶囊，用于确定患者体内活体组织的血液含量以检测肿瘤。 胶囊包括光源和用于将光引导到组织上并用于从其接收相互作用的光的光检测器。 通过分析相互作用的光，可以确定该组织的血液含量。 存在定影胶囊的各种方式，使得其以光源和光检测器的期望定向接触组织。 还有一种用于确定胶囊和组织之间的实际接触的系统。 还使用校准系统，其允许在使用胶囊之前容易且准确地进行自校准。

公开(公告)号：US08888680B2

公开(公告)日：2014-11-18

申请号：US12168418

申请日：2008-07-07

Applicant: Kazuhiro Gono ,  Takeshi Suga

Inventor： Kazuhiro Gono ,  Takeshi Suga

IPC: A61B1/04 ,  A61B1/06 ,  A61B1/12 ,  A61B5/00 ,  A61B1/00 ,  A61B5/07

CPC classification number: A61B1/041 ,  A61B1/00009 ,  A61B1/00057 ,  A61B1/0638 ,  A61B1/126 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/073

Abstract: Apparatus and methods for detecting foreign material obstructing a blood content sensor window to facilitate higher data accuracy from such sensors, in accordance with one embodiment of the invention for detecting foreign matter with the blood content sensor when the blood content sensor is not contacted with living tissue, an illuminator for blood content detection and the blood content sensor share a common outer window. When the window is at a distance from tissue and in absence of foreign matter on the window, all or most of the emitted light will be dispersed and little or no light will be reflected back into the sensor. Conversely, when the window is at a distance from tissue and foreign matter is present on the window, a substantial portion of the emitted light will be reflected back into the sensor indicating the presence of the foreign matter.

Abstract translation: 根据本发明的一个实施例，当血液含量传感器不与生物组织接触时，用于检测异物的阻挡血液含量传感器窗口以便于更高数据精度的装置和方法， ，用于血液含量检测的照明器和血液含量传感器共享共同的外窗。 当窗口距离组织一定距离并且在窗口上没有异物时，所有或大部分发射的光将被分散，很少或没有光将被反射回到传感器中。 相反，当窗口距离组织一定距离并且异物存在于窗口上时，发射的光的大部分将被反射回到传感器中，指示异物的存在。

公开(公告)号：US08836939B2

公开(公告)日：2014-09-16

申请号：US13482730

申请日：2012-05-29

Applicant: Kazuhiro Gono

Inventor： Kazuhiro Gono

IPC: G01J1/02 ,  A61B1/12 ,  A61B1/00

CPC classification number: A61B1/0017 ,  A61B1/00057 ,  A61B1/12

Abstract: A probe detachably connected to an optical measurement apparatus includes: a fiber that emits light by the optical measurement apparatus, and outputs reflected light and/or scattered light from an object to be measured; a covering member that covers a side face of the fiber; a cap that covers a distal end of the probe; a standard object that is provided on a surface of the cap facing the distal end of the fiber and that is used in calibration measurement by light emitted from the distal end of the fiber; an adhesive member that adheres the cap to the distal end of the probe and is made of an adhesive material; a heat-generating portion that generates heat to be applied to the adhesive member; and a thermal conduction portion that conducts heat that decreases the adhesive strength of the adhesive material with respect to the covering member.

Abstract translation: 可拆卸地连接到光学测量装置的探针包括：由光学测量装置发射光并从被测量物体输出反射光和/或散射光的光纤; 覆盖所述纤维的侧面的覆盖部件; 盖子覆盖探头的远端; 提供在面向所述纤维的远端的所述帽的表面上并且用于通过从所述纤维的远端发射的光进行校准测量的标准物体; 粘合剂构件，其将盖粘附到探针的远端并由粘合材料制成; 发热部，其产生施加于所述粘接部件的热量; 以及传导热量的导热部分，其降低粘合剂材料相对于覆盖部件的粘合强度。