公开(公告)号：US09291566B2

公开(公告)日：2016-03-22

申请号：US14170349

申请日：2014-01-31

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Joseph Bartel ,  Yongfen Chen ,  Eric Tulsky ,  Joseph Treadway

IPC: A61K9/14 ,  G01N21/64 ,  B82Y5/00 ,  B82Y15/00 ,  C01B25/08 ,  C30B7/00 ,  C30B29/40 ,  C30B29/48 ,  C30B29/60 ,  G01N33/58 ,  H01L33/06 ,  C09K11/02 ,  C09K11/56 ,  C09K11/70 ,  H01L21/02

CPC classification number: G01N21/6486 ,  B82Y5/00 ,  B82Y15/00 ,  C01B25/082 ,  C09K11/02 ,  C09K11/565 ,  C09K11/70 ,  C30B7/00 ,  C30B29/40 ,  C30B29/48 ,  C30B29/60 ,  G01N33/588 ,  H01L21/02392 ,  H01L21/02557 ,  H01L21/02601 ,  H01L21/02628 ,  H01L33/06

Abstract: Nanocrystals having an indium-based core and methods for making them and using them to construct core-shell nanocrystals are described. These core-shell nanocrystals are highly stable and provide higher quantum yields than known nanocrystals of similar composition, and they provide special advantages for certain applications because of their small size.

Abstract translation: 描述了具有铟基核的纳米晶体及其制备方法和用于构建核壳纳米晶体的方法。 这些核 - 壳纳米晶体是高度稳定的并且提供比已知具有类似组成的纳米晶体更高的量子产率，并且由于它们的小尺寸，它们为某些应用提供了特殊的优点。

公开(公告)号：US20150233936A1

公开(公告)日：2015-08-20

申请号：US14590840

申请日：2015-01-06

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Eric TULSKY ,  Kari Haley ,  Imad Naasani ,  John Mauro ,  Roman Rozhkov ,  Joseph Treadway

IPC: G01N33/58 ,  G01N21/64 ,  G01N1/30

CPC classification number: G01N33/588 ,  B01J13/14 ,  B22F1/0022 ,  B22F1/02 ,  B82Y30/00 ,  G01N1/30 ,  G01N21/64 ,  G01N2001/302 ,  Y10S977/773 ,  Y10S977/81 ,  Y10S977/834 ,  Y10S977/902

Abstract: Provided herein are methods for making water-soluble nanoparticles comprising a core/shell nanocrystal that is coated with a surface layer comprising enough hydrophilic ligands to render the nanoparticle water soluble or water dispersable. Methods for crosslinking molecules on the surface of a nanoparticle, which methods can be used on the above water-soluble nanoparticles also are provided. Nanoparticle compositions resulting from these methods are also provided.

Abstract translation: 本文提供了制备包含核/壳纳米晶体的水溶性纳米颗粒的方法，其被包覆有包含足够亲水性配体的表面层以使纳米颗粒水溶性或水分散。 还提供了在纳米颗粒表面上交联分子的方法，该方法可用于上述水溶性纳米颗粒。 还提供了由这些方法得到的纳米颗粒组合物。