公开(公告)号：US20240261565A1

公开(公告)日：2024-08-08

申请号：US18637667

申请日：2024-04-17

Applicant: MAGENTA MEDICAL LTD

Inventor： Yuri TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/859 ,  A61L29/02 ,  A61M60/13 ,  A61M60/174 ,  A61M60/242 ,  A61M60/414 ,  A61M60/806 ,  A61M60/81 ,  A61M60/825

CPC classification number: A61M60/859 ,  A61L29/02 ,  A61M60/13 ,  A61M60/174 ,  A61M60/242 ,  A61M60/414 ,  A61M60/806 ,  A61M60/81 ,  A61M60/825

Abstract: Apparatus and methods are described including an axial shaft configured for insertion into, and rotation within, a subject's body. A delivery tube extends to the axial shaft, from outside the subject's body, while the axial shaft is within the subject's body. An impeller is coupled to the axial shaft such that, as the axial shaft rotates, the impeller pumps blood of the subject. Proximal and distal radial bearings surround the axial shaft, proximally and distally to the impeller respectively, the proximal and distal radial bearings being configured to radially stabilize the axial shaft while the axial shaft rotates. A proximal bearing housing houses the proximal radial bearing and is coupled to the delivery tube. A drive cable rotates the axial shaft while extending through the delivery tube, and is coupled to the axial shaft within the proximal bearing housing. Other applications are also described.

公开(公告)号：US20240252808A1

公开(公告)日：2024-08-01

申请号：US18632557

申请日：2024-04-11

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/178 ,  A61M60/216 ,  A61M60/295 ,  A61M60/408 ,  A61M60/818

CPC classification number: A61M60/178 ,  A61M60/216 ,  A61M60/295 ,  A61M60/408 ,  A61M60/818

Abstract: Apparatus and methods are described including a left-ventricular assist device that includes a pump-outlet tube shaped to define one or more laterally-facing blood-outlet openings and including a first section and a second section that overlap one another between the laterally-facing blood-outlet openings. The pump-outlet tube is configured for insertion, through an aorta of a subject, into a left ventricle of a heart of the subject such that the pump-outlet tube traverses an aortic valve of the subject with the lateral blood-outlet openings being disposed within the aorta. An impeller is disposed within the first section of the pump-outlet tube and is configured to pump blood of the subject, through the laterally-facing blood-outlet openings, from the left ventricle into the aorta. Other applications are also described.

公开(公告)号：US20180169313A1

公开(公告)日：2018-06-21

申请号：US15574948

申请日：2016-05-18

Applicant: MAGENTA MEDICAL LTD.

Inventor： Ehud SCHWAMMENTHAL ,  Yosi TUVAL ,  Daniel GLOZMAN ,  Tom SHTENDEL ,  Gad LUBINSKY

IPC: A61M1/10 ,  A61M1/12

CPC classification number: A61M1/1012 ,  A61M1/101 ,  A61M1/1013 ,  A61M1/1018 ,  A61M1/1024 ,  A61M1/1029 ,  A61M1/1034 ,  A61M1/1086 ,  A61M1/122 ,  A61M1/125

Abstract: Apparatus and methods are described, including a catheter (20) configured to be placed inside a blood vessel of a subject. A first impeller (28) is disposed on the catheter, and a second impeller (28) is disposed on the catheter, proximally to the first impeller. A support structure (160) is disposed upon the catheter such that a longitudinal center of the support structure is disposed between the first and second impellers, the support structure being configured to support an inner wall of the blood vessel in an open configuration in a region between the first and second impellers. Other applications are also described.

公开(公告)号：US20240359001A1

公开(公告)日：2024-10-31

申请号：US18767628

申请日：2024-07-09

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Ehud Schwammenthal ,  Daniel GLOZMAN ,  Gad LUBINSKY

IPC: A61M60/833 ,  A61M60/13 ,  A61M60/139 ,  A61M60/216 ,  A61M60/414 ,  A61M60/416 ,  A61M60/531 ,  A61M60/585 ,  A61M60/804 ,  A61M60/818

CPC classification number: A61M60/833 ,  A61M60/13 ,  A61M60/139 ,  A61M60/216 ,  A61M60/416 ,  A61M60/531 ,  A61M60/585 ,  A61M60/804 ,  A61M60/818 ,  A61M60/414

Abstract: Apparatus and methods are described including reducing cardiac preload of a subject by partially occluding a vena cava of the subject at an infra-renal location. One or more physiological parameters of the subject are monitored, the one or more physiological parameters including lower body venous pressure, central venous pressure, central venous blood flow, renal venous pressure, cardiac diameter, cardiac volume, arterial pressure, and/or arterial blood flow. An extent to which the vena cava is occluded at the infra-renal location is modulated, responsively to the one or more physiological parameters. Other applications are also described.

公开(公告)号：US20240285934A1

公开(公告)日：2024-08-29

申请号：US18640285

申请日：2024-04-19

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/865 ,  A61M60/13 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/585 ,  A61M60/808 ,  A61M60/816 ,  A61M60/818

CPC classification number: A61M60/865 ,  A61M60/13 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/585 ,  A61M60/808 ,  A61M60/816 ,  A61M60/818 ,  A61M2205/02 ,  A61M2205/04 ,  A61M2205/103 ,  A61M2205/3303 ,  A61M2205/3306 ,  A61M2205/3327 ,  A61M2205/3331 ,  A61M2205/502 ,  A61M2210/125 ,  A61M2230/30

Abstract: Apparatus and methods are described including a blood pump including an axial shaft configured for insertion into, and rotation within, a body of a subject, and an impeller coupled to the axial shaft such that, as the axial shaft rotates, the impeller pumps blood of the subject. A frame surrounds the impeller. One or more steering wires are coupled to the frame and configured to extend from the frame, to outside the body of the subject, while the frame is within the body. Other applications are also described.

公开(公告)号：US20240278002A1

公开(公告)日：2024-08-22

申请号：US18637653

申请日：2024-04-17

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/90 ,  A61M60/13 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/806 ,  A61M60/81 ,  A61M60/818

CPC classification number: A61M60/90 ,  A61M60/13 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/806 ,  A61M60/81 ,  A61M60/818 ,  A61M2205/04 ,  A61M2205/103 ,  A61M2205/3606 ,  A61M2205/50 ,  A61M2207/10

Abstract: Apparatus and methods are described including inserting a drive-cable end of a drive cable, which includes a plurality of coiled wires, and a hollow-shaft end of a hollow shaft, which hollow-shaft end is shaped to define multiple shaft pores, into opposing ends of a coupling tube, which is shaped to define multiple coupling-tube pores. While the drive-cable end and hollow-shaft end are inside the coupling tube, a molten material is flowed between the coiled wires at the drive-cable end via the coupling-tube pores, and into the hollow-shaft end via the coupling-tube pores and shaft pores, such that, upon solidifying, the material bonds the drive cable to the shaft. Other applications are also described.

公开(公告)号：US20240278000A1

公开(公告)日：2024-08-22

申请号：US18639098

申请日：2024-04-18

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/825 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/531 ,  A61M60/585 ,  A61M60/808 ,  A61M60/81 ,  A61M60/829

CPC classification number: A61M60/825 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/531 ,  A61M60/585 ,  A61M60/808 ,  A61M60/81 ,  A61M60/829 ,  A61M2205/04 ,  A61M2205/103 ,  A61M2205/502 ,  A61M2210/125

Abstract: Apparatus and methods are described including a blood pump that includes an axial shaft configured for insertion into, and rotation within, a subject's body, and an impeller coupled to the axial shaft such that, as the axial shaft rotates, the impeller pumps blood of the subject. A frame surrounds the impeller and includes a distal conical portion. A bearing adjacent to the axial shaft is configured to stabilize the axial shaft while the axial shaft rotates. A bearing housing houses the bearing. The bearing housing is disposed at least partly within the distal conical portion of the frame such that at least 50% of the length of the bearing housing is disposed within the frame. Other applications are also described.

公开(公告)号：US20240277991A1

公开(公告)日：2024-08-22

申请号：US18640260

申请日：2024-04-19

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/178 ,  A61M60/237 ,  A61M60/419 ,  A61M60/531 ,  A61M60/818 ,  A61M60/829

CPC classification number: A61M60/178 ,  A61M60/237 ,  A61M60/419 ,  A61M60/531 ,  A61M60/818 ,  A61M60/829

Abstract: Apparatus and methods are described including a blood pump that includes an axial shaft configured for insertion into, and rotation within, a left ventricle of a subject, and an impeller coupled to the axial shaft such that, as the axial shaft rotates, the impeller pumps blood from the left ventricle. A frame surrounds the impeller and a tip portion is coupled to a distal end of the frame. The tip portion includes a distal curved portion, which, when deployed within the left ventricle, lies in a plane, and a proximal curved portion, which, when deployed within the left ventricle, does not lie in the plane and is curved such that, following the insertion of the axial shaft into the left ventricle via an aorta of the subject, a distal end of the proximal curved portion points toward an apex of the left ventricle. Other applications are also described.

公开(公告)号：US20240261561A1

公开(公告)日：2024-08-08

申请号：US18632569

申请日：2024-04-11

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/178 ,  A61M60/226 ,  A61M60/419 ,  A61M60/531 ,  A61M60/538 ,  A61M60/818 ,  A61M60/829 ,  A61M60/865

CPC classification number: A61M60/178 ,  A61M60/226 ,  A61M60/419 ,  A61M60/531 ,  A61M60/538 ,  A61M60/818 ,  A61M60/829 ,  A61M60/865

Abstract: Apparatus and methods are described including a left-ventricular assist device that includes a pump-outlet tube shaped to define one or more blood-outlet openings and including a narrower section, and a wider section, which is proximal to and wider than the narrower section, and which is shaped to define at least a portion of each of the blood-outlet openings such that a normal vector to the portion has a distally-facing component. The pump-outlet tube is inserted, through the subject's aorta, into the subject's left ventricle such that the pump-outlet tube traverses an aortic valve of the subject with the blood-outlet openings being disposed within the aorta. An impeller is disposed within the narrower section of the pump-outlet tube and is configured to pump blood of the subject, through the blood-outlet openings, from the left ventricle into the aorta. Other applications are also described.

公开(公告)号：US20250010060A1

公开(公告)日：2025-01-09

申请号：US18889744

申请日：2024-09-19

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/90 ,  A61L29/02 ,  A61M39/10 ,  A61M60/13 ,  A61M60/17 ,  A61M60/174 ,  A61M60/178 ,  A61M60/216 ,  A61M60/226 ,  A61M60/237 ,  A61M60/242 ,  A61M60/295 ,  A61M60/408 ,  A61M60/414 ,  A61M60/419 ,  A61M60/497 ,  A61M60/508 ,  A61M60/531 ,  A61M60/538 ,  A61M60/554 ,  A61M60/585 ,  A61M60/806 ,  A61M60/808 ,  A61M60/81 ,  A61M60/816 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/859 ,  A61M60/865

Abstract: Apparatus and methods are described including a blood pump that includes a pump-outlet tube shaped to define one or more blood-outlet openings and configured for insertion into a heart of a subject. An impeller is disposed within a distal portion of the pump-outlet tube and is configured to pump blood of the subject proximally through the pump-outlet tube, such that the blood exits the pump-outlet tube through the blood-outlet openings. A delivery tube extends, from outside a body of the subject, through the pump-outlet tube to the distal portion. A drive cable passes through the delivery tube and is configured to rotate the impeller. A proximal portion of the pump-outlet tube includes multiple strips adhered to the delivery tube. Other embodiments are also described.