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公开(公告)号:US20250114593A1
公开(公告)日:2025-04-10
申请号:US18933759
申请日:2024-10-31
Applicant: MAGENTA MEDICAL LTD
Inventor: Yosi TUVAL , Gad LUBINSKY , Yuri SUDIN , Avi ROZENFELD , Shaul MUSTACCHI , Ran TAMIR , David LINSKY
IPC: A61M60/855 , A61M60/13 , A61M60/17 , A61M60/216 , A61M60/408 , A61M60/833
Abstract: Apparatus and methods are described including a delivery catheter and a delivery tube configured to extend from outside a subject's body into the subject's left ventricle via the delivery catheter. A locking unit is configured to couple to a proximal end of the delivery catheter and the delivery tube is configured to pass through the locking unit. The locking unit includes at least one internal seal configured to surround the delivery tube and to inhibit backflow of blood of the subject, from the delivery catheter, through the locking unit. The locking unit also includes a clip, which has only two states, which consist of a closed state, in which the clip grips the delivery tube so as to inhibit movement of the delivery tube relative to the delivery catheter, and an open state, in which the clip does not grip the delivery tube. Other applications are also described.
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公开(公告)号:US20240277990A1
公开(公告)日:2024-08-22
申请号:US18635275
申请日:2024-04-15
Applicant: MAGENTA MEDICAL LTD
Inventor: Yosi TUVAL , Gad LUBINSKY , Yuri SUDIN , Avi ROZENFELD , Shaul MUSTACCHI , Ran TAMIR
IPC: A61M60/178 , A61M60/216 , A61M60/408 , A61M60/419 , A61M60/497 , A61M60/508 , A61M60/531 , A61M60/818 , A61M60/829 , A61M60/865
CPC classification number: A61M60/178 , A61M60/216 , A61M60/408 , A61M60/419 , A61M60/497 , A61M60/508 , A61M60/531 , A61M60/818 , A61M60/829 , A61M60/865
Abstract: Apparatus and methods are provided, including a left-ventricular assist device that includes an impeller configured for insertion into a subject's left ventricle. A delivery tube passes through the subject's aorta, from outside the subject into the left ventricle. The delivery tube includes an outer layer that varies along a length of the delivery tube such that a flexural rigidity of the delivery tube at a first portion of the delivery tube, which is configured to traverse the aortic valve, is less than the flexural rigidity at a second portion, which is configured to traverse at least a portion of the aortic arch, and the flexural rigidity at the second portion is less than the flexural rigidity at a third portion, which is configured to traverse the descending aorta. Other applications are also described.
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公开(公告)号:US20180228951A1
公开(公告)日:2018-08-16
申请号:US15888771
申请日:2018-02-05
Applicant: MAGENTA MEDICAL LTD.
Inventor: Ehud SCHWAMMENTHAL , Yosi TUVAL , Daniel GLOZMAN
CPC classification number: A61M1/1018 , A61B17/12136 , A61B17/12168 , A61B2017/12127 , A61M1/1008 , A61M1/1024 , A61M1/1031 , A61M1/125 , A61M2205/505 , A61M2205/52 , A61M2205/80 , A61M2230/005 , A61M2230/20 , A61M2230/30
Abstract: Apparatus and methods are described including a catheter, a first pump disposed on the catheter, and a second pump disposed on the catheter, proximally to the first pump. A control unit is configured to control activation of the first and second pumps. The first and second pumps are configured, when activated, to pump fluid in opposite directions from one another. Other applications are also described.
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公开(公告)号:US20160051741A1
公开(公告)日:2016-02-25
申请号:US14931363
申请日:2015-11-03
Applicant: MAGENTA MEDICAL LTD.
Inventor: Ehud SCHWAMMENTHAL , Yosi TUVAL , Daniel GLOZMAN
CPC classification number: A61M1/125 , A61B5/02055 , A61F2/07 , A61M1/1008 , A61M1/101 , A61M1/1018 , A61M1/1024 , A61M1/1031 , A61M1/1034 , A61M1/1037 , A61M1/106 , A61M1/1086 , A61M1/1098 , A61M1/122 , A61M2207/00 , A61M2210/1082 , A61M2210/12
Abstract: Apparatus and methods are described including identifying a subject as suffering from a condition selected from the group consisting of: cardiac dysfunction, congestive heart failure, reduced renal blood flow, increased renal vascular resistance, arterial hypertension, and kidney dysfunction. In response thereto, blood pressure within a renal vein of the subject is reduced, by placing a blood pump inside the subject's renal vein and activating the impeller to pump blood from the renal vein into the subject's vena cava. Other applications are also described.
Abstract translation: 描述的装置和方法包括将受试者识别为患有选自以下的病症:心脏功能障碍,充血性心力衰竭,肾血流量减少,肾血管阻力增加,动脉高血压和肾功能障碍。 作为响应,通过将血液泵放置在受试者的肾静脉内并激活叶轮以将血液从肾静脉泵送到受试者的腔静脉中,使受试者的肾静脉内的血压降低。 还描述了其它应用。
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公开(公告)号:US20160022890A1
公开(公告)日:2016-01-28
申请号:US14774081
申请日:2014-03-13
Applicant: MAGENTA MEDICAL LTD.
Inventor: Ehud SCHWAMMENTHAL , Yosi TUVAL , Daniel GLOZMAN
IPC: A61M1/12 , A61M1/10 , A61B5/0205 , A61F2/07
CPC classification number: A61M1/125 , A61B5/02055 , A61F2/07 , A61M1/1008 , A61M1/101 , A61M1/1018 , A61M1/1024 , A61M1/1031 , A61M1/1034 , A61M1/1037 , A61M1/106 , A61M1/1086 , A61M1/1098 , A61M1/122 , A61M2207/00 , A61M2210/1082 , A61M2210/12
Abstract: Apparatus and methods are described including identifying a subject as suffering from a condition selected from the group consisting of: cardiac dysfunction, congestive heart failure, reduced renal blood flow, increased renal vascular resistance, arterial hypertension, and kidney dysfunction. In response thereto, blood pressure within a renal vein (32) of the subject is reduced, by placing a blood pump (150) inside the subject's renal vein and activating the impeller to pump blood from the renal vein into the subject's vena cava (26). Other applications are also described.
Abstract translation: 描述的装置和方法包括将受试者识别为患有选自以下的病症:心脏功能障碍,充血性心力衰竭,肾血流量减少,肾血管阻力增加,动脉高血压和肾功能障碍。 作为响应,通过将血液泵(150)放置在受试者的肾静脉内并激活叶轮以将血液从肾静脉泵送到受试者的腔静脉(26)中来减少受试者的肾静脉(32)内的血压 )。 还描述了其它应用。
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公开(公告)号:US20250073445A1
公开(公告)日:2025-03-06
申请号:US18933745
申请日:2024-10-31
Applicant: MAGENTA MEDICAL LTD
Inventor: Yosi TUVAL , Gad LUBINSKY , Yuri SUDIN , Avi ROZENFELD , Shaul MUSTACCHI , Ran TAMIR
IPC: A61M60/216 , A61M60/122 , A61M60/414 , A61M60/825 , A61M60/90
Abstract: Apparatus and methods are described including a blood pump that includes an axial shaft configured for insertion into, and rotation within, a subject's body. The blood pump also includes an impeller coupled to the axial shaft such that, as the axial shaft rotates, the impeller pumps blood of the subject. Proximal and distal radial bearings surround the axial shaft and are configured to radially stabilize the axial shaft while the axial shaft rotates. Proximal and distal sleeves, which are less flexible than the axial shaft, are disposed around the axial shaft, such that the proximal and distal sleeves contact the proximal and distal radial bearings, respectively, as the axial shaft rotates. A ratio between a length of the axial shaft and a combined length of the proximal sleeve and distal sleeve is between 2:1 and 6:1. Other applications are also described.
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公开(公告)号:US20240285928A1
公开(公告)日:2024-08-29
申请号:US18635292
申请日:2024-04-15
Applicant: MAGENTA MEDICAL LTD
Inventor: Yosi TUVAL , Gad LUBINSKY , Yuri SUDIN , Avi ROZENFELD , Shaul MUSTACCHI , Ran TAMIR
IPC: A61M60/237 , A61M60/174 , A61M60/857
CPC classification number: A61M60/237 , A61M60/174 , A61M60/857
Abstract: Apparatus and methods are provided, including inserting an impeller and a delivery tube into a subject's body, the delivery tube including a braid having a pick density that varies along the delivery tube's length such that a flexural rigidity of the delivery tube at a first portion of the delivery tube is less than the flexural rigidity at a second portion of the delivery tube, and the flexural rigidity at the second portion is less than the flexural rigidity at a third portion of the delivery tube. The impeller and delivery tube are positioned such that the impeller is disposed within the subject's left ventricle and the delivery tube passes the subject's aorta into the left ventricle. Using a drive cable, which passes through the delivery tube, the impeller is rotated so as to pump blood from the left ventricle into the aorta. Other applications are also described.
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公开(公告)号:US20240277999A1
公开(公告)日:2024-08-22
申请号:US18639094
申请日:2024-04-18
Applicant: MAGENTA MEDICAL LTD
Inventor: Yosi TUVAL , Gad LUBINSKY , Yuri SUDIN , Avi ROZENFELD , Shaul MUSTACCHI , Ran TAMIR
IPC: A61M60/825 , A61M60/13 , A61M60/174 , A61M60/242 , A61M60/414 , A61M60/808 , A61M60/81 , A61M60/865
CPC classification number: A61M60/825 , A61M60/13 , A61M60/174 , A61M60/242 , A61M60/414 , A61M60/808 , A61M60/81 , A61M60/865
Abstract: Apparatus and methods are described including a blood pump that includes an axial shaft configured for insertion, over a guidewire, into a subject's body, and for rotation within the subject's body. The axial shaft is shaped to define a shaft lumen for passage of the guidewire therethrough. An impeller is coupled to the axial shaft such that, as the axial shaft rotates, the impeller pumps blood of the subject. A thrust bearing is disposed distally from the axial shaft so as to inhibit distal movement of the axial shaft beyond the thrust bearing. The thrust bearing is shaped to define a bearing lumen that is configured to be continuous with the shaft lumen. At least a portion of the bearing lumen is frustoconically-shaped, a wider end of the frustoconically-shaped portion of the bearing lumen facing distally. Other applications are also described.
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公开(公告)号:US20240252808A1
公开(公告)日:2024-08-01
申请号:US18632557
申请日:2024-04-11
Applicant: MAGENTA MEDICAL LTD
Inventor: Yosi TUVAL , Gad LUBINSKY , Yuri SUDIN , Avi ROZENFELD , Shaul MUSTACCHI , Ran TAMIR
IPC: A61M60/178 , A61M60/216 , A61M60/295 , A61M60/408 , A61M60/818
CPC classification number: A61M60/178 , A61M60/216 , A61M60/295 , A61M60/408 , A61M60/818
Abstract: Apparatus and methods are described including a left-ventricular assist device that includes a pump-outlet tube shaped to define one or more laterally-facing blood-outlet openings and including a first section and a second section that overlap one another between the laterally-facing blood-outlet openings. The pump-outlet tube is configured for insertion, through an aorta of a subject, into a left ventricle of a heart of the subject such that the pump-outlet tube traverses an aortic valve of the subject with the lateral blood-outlet openings being disposed within the aorta. An impeller is disposed within the first section of the pump-outlet tube and is configured to pump blood of the subject, through the laterally-facing blood-outlet openings, from the left ventricle into the aorta. Other applications are also described.
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公开(公告)号:US20180169313A1
公开(公告)日:2018-06-21
申请号:US15574948
申请日:2016-05-18
Applicant: MAGENTA MEDICAL LTD.
Inventor: Ehud SCHWAMMENTHAL , Yosi TUVAL , Daniel GLOZMAN , Tom SHTENDEL , Gad LUBINSKY
CPC classification number: A61M1/1012 , A61M1/101 , A61M1/1013 , A61M1/1018 , A61M1/1024 , A61M1/1029 , A61M1/1034 , A61M1/1086 , A61M1/122 , A61M1/125
Abstract: Apparatus and methods are described, including a catheter (20) configured to be placed inside a blood vessel of a subject. A first impeller (28) is disposed on the catheter, and a second impeller (28) is disposed on the catheter, proximally to the first impeller. A support structure (160) is disposed upon the catheter such that a longitudinal center of the support structure is disposed between the first and second impellers, the support structure being configured to support an inner wall of the blood vessel in an open configuration in a region between the first and second impellers. Other applications are also described.
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