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    Dermocosmetic Preparations
    11.
    发明申请
    Dermocosmetic Preparations 审中-公开
    皮肤科药物制剂

    公开(公告)号：US20080220031A1

    公开(公告)日：2008-09-11

    申请号：US11996424

    申请日：2006-07-14

    申请人： Thomas Wunsch ,  Sylke Haremza ,  Axel Jentzsch ,  Gerhard Wagenblast

    发明人： Thomas Wunsch ,  Sylke Haremza ,  Axel Jentzsch ,  Gerhard Wagenblast

    IPC分类号： A61K8/49 ,  A61Q5/00 ,  A61Q19/00 ,  A61K8/06

    CPC分类号： A61K8/4926 ,  A61K8/817 ,  A61K2800/522 ,  A61Q1/02 ,  A61Q5/02 ,  A61Q5/06 ,  A61Q5/12 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/002 ,  A61Q19/004 ,  A61Q19/10

    摘要： The present invention relates to dermocosmetic compositions comprising a compound comprising the structural element of the formula I where the radical Z has the following meaning: H, C1-C22alkyl group, C6-C10-aryl group, C1-C22-alkoxy group or a C6-C10-O-aryl group substituted by a C1-C22-alkyl or C-C22-alkoxy group,and the radicals R1 to R6, independently of one another, have the following meaning: H, C1-C22-alkyl group, C6-C10-aryl group, O, OH, C1-C22-alkoxy group or a C6-C10-O-aryl group substituted by a C1-C22-alkyl or C1-C22-alkoxy group,it being possible for R5 and R6 to be bridged in such a way that a five- to eight-membered ring is formed and, in the case of a five-membered ring, this ring may be part of an oligomer as a result of covalent bonds at positions 3 and 4.The invention furthermore relates to the use of said compounds in dermocosmetic formulations and the use of the dermocosmetics according to the invention for reducing skin or hair damage caused by free radicals. The invention furthermore relates to the use of the compounds according to the invention for increasing the stability of dermocosmetic formulations.

    摘要翻译： 本发明涉及皮肤科药物组合物，其包含包含式I结构元素的化合物，其中基团Z具有以下含义：H，C 1 -C 22烷基 C 6 -C 10 - 芳基，C 1 -C 22 - 烷氧基或C 1 -C 12 - 被C 1 -C 22 -C 22 - 烷基取代的芳基或CC 22个 - 烷氧基，基团R 1至R 6彼此独立地具有如下含义：H，C 1 C 22 - - - 烷基，C 6 -C 10 - 芳基，O，OH，C 1 -C 22 - 烷氧基或被C 1 -C 6烷基取代的C 6 -C 10 -C 10 -O-芳基， C 1 -C 22烷基或C 1 -C 22 - 烷氧基，可以是R 5 和R 6以桥接形式形成五至八元环，并且在五元环的情况下， 由于位置3和4的共价键，s环可以是低聚物的一部分。本发明还涉及所述化合物在皮肤科药物制剂中的用途以及根据本发明的皮肤用品用于减少皮肤或毛发损伤的用途 由自由基。 本发明还涉及根据本发明的化合物用于增加皮肤科药物制剂的稳定性的用途。

    Cosmetic or pharmaceutical preparations which comprise enaminotriazines as light protection agents, and novel enaminotriazines
    12.
    发明申请
    Cosmetic or pharmaceutical preparations which comprise enaminotriazines as light protection agents, and novel enaminotriazines 失效
    包含氨基三嗪作为防晒剂的化妆品或药物制剂，以及新的氨基三嗪

    公开(公告)号：US20050089487A1

    公开(公告)日：2005-04-28

    申请号：US10984241

    申请日：2004-11-10

    申请人： Thomas Heidenfelder ,  Kristin Tiefensee ,  Thomas Wunsch

    发明人： Thomas Heidenfelder ,  Kristin Tiefensee ,  Thomas Wunsch

    IPC分类号： A61K8/00 ,  A61K8/49 ,  A61K31/53 ,  A61P17/16 ,  A61Q17/04 ,  A61Q19/00 ,  C07D251/70 ,  A61K7/42

    CPC分类号： A61Q17/04 ,  A61K8/4966 ,  C07D251/70

    摘要： The invention relates to the use of enaminotriazines of the formula I in which the radicals Y, independently of one another, are hydrogen, an optionally substituted aliphatic, cycloaliphatic, araliphatic or aromatic radical having in each case up to 18 carbon atoms, the radicals X are identical or different, where at least one of the radicals X is the ethenyl radical of the formula II and X may also have the meanings of Y, and where in the formula II the radicals R are identical or different and are cyano, optionally esterified carboxyl, substituted carbonyl, optionally substituted aminocarbonyl, optionally esterified sulfo, substituted sulfonyl or optionally esterified phosphono, and where two adjacent radicals R may optionally form a ring and the radicals R′ are identical or different and are hydrogen, an optionally substituted aliphatic, cycloaliphatic or aromatic radical having in each case up to 18 carbon atoms, as UV filters in cosmetic or pharmaceutical preparations for protecting human skin or human hair against solar rays, alone or together with compounds which absorb in the UV region and which are known per se for cosmetic preparations.

    摘要翻译： 本发明涉及式I的氨基三嗪的用途，其中基团Y彼此独立地为氢，任选取代的脂族，脂环族，芳脂族或芳族基团，其中每种情况最多可达18个碳原子，基团X 相同或不同，其中基团X中的至少一个是式II的乙烯基，X也可以具有Y的含义，并且其中在式II中，基团R相同或不同并且是氰基，任选地被酯化 羧基，取代的羰基，任选取代的氨基羰基，任选酯化的磺基，取代的磺酰基或任选酯化的膦酰基，并且其中两个相邻的基团R可以任选地形成环，并且基团R'相同或不同，并且是氢，任选取代的脂族，脂环族 或在每种情况下最多18个碳原子的芳族基团，作为化妆品中的UV过滤剂或用于保护的药物制剂 人类皮肤或人类头发抵抗太阳光线，单独或与在UV区域吸收的化合物一起，并且本身已知本身用于化妆品制剂。

    Materials suitable as crosslinkable binder components
    13.
    发明授权
    Materials suitable as crosslinkable binder components 失效
    适合作为可交联粘合剂组分的材料

    公开(公告)号：US5473042A

    公开(公告)日：1995-12-05

    申请号：US370608

    申请日：1995-01-10

    申请人： Gregor Brodt ,  Thomas Wunsch ,  August Lehner ,  Albert Kohl

    发明人： Gregor Brodt ,  Thomas Wunsch ,  August Lehner ,  Albert Kohl

    IPC分类号： C08G18/12 ,  C08G18/65 ,  C09D5/23 ,  G11B5/702 ,  C08G18/10

    CPC分类号： G11B5/7021 ,  C08G18/12 ,  C08G18/6517 ,  C08G18/6535

    摘要： A material suitable as crosslinking binder component for pigment-containing coatings and having an average molecular weight of from 25,000 to 150,000, obtainable by reacting a polyurethane comprising a diol having a molecular weight between 400 and 4,000, an aliphatic or cycloaliphatic diol of 2-18 carbon atoms, an aromatic diol of 8-36 carbon atoms, a trihydric or polyhydric alcohol of 3-18 carbon atoms, a polyhydric alcohol of 3-40 carbon atoms containing a tertiary amino group, and a diisocyanate of 3-34 carbon atoms with a compound containing one or more hydroxyl groups and one or more amino groups reactive toward isocyanate groups. The materials may be used as crosslinkable binder components for pigment-containing coatings, in particular for the production of magnetic recording materials.

    摘要翻译： 适合作为含颜料的涂料的交联粘合剂组分的材料，其平均分子量为25,000至150,000，可通过使包含分子量为400至4000的二醇的聚氨酯，2-18的脂族或脂环族二醇 碳原子，8-36个碳原子的芳族二醇，3-18个碳原子的三元或多元醇，含有叔氨基的3-40个碳原子的多元醇和3-34个碳原子的二异氰酸酯与 含有一个或多个羟基和一个或多个对异氰酸酯基团反应的氨基的化合物。 这些材料可以用作含颜料的涂料的可交联粘合剂组分，特别是用于生产磁记录材料。

    Materials suitable as crosslinkable binder components
    18.
    发明授权
    Materials suitable as crosslinkable binder components 失效
    适合作为可交联粘合剂组分的材料

    公开(公告)号：US5922469A

    公开(公告)日：1999-07-13

    申请号：US839703

    申请日：1997-04-15

    申请人： Thomas Wunsch ,  Gregor Brodt ,  Ria Kress ,  Norbert Schneider ,  Albert Kohl ,  August Lehner ,  Werner Balz

    发明人： Thomas Wunsch ,  Gregor Brodt ,  Ria Kress ,  Norbert Schneider ,  Albert Kohl ,  August Lehner ,  Werner Balz

    IPC分类号： C08G18/12 ,  C08G18/61 ,  C08G18/65 ,  C08G18/66 ,  C09D5/23 ,  C09D175/00 ,  C09D175/04 ,  G11B5/702 ,  B32B27/40

    CPC分类号： G11B5/7021 ,  C08G18/12 ,  C08G18/61 ,  C08G18/6517 ,  C08G18/6535 ,  C08G18/6637 ,  Y10S428/90 ,  Y10T428/31609

    摘要： Preparation of materials (I) having an average molecular weight from 4000 to 30,000, obtainable by reacting1) a polyurethane (II) comprisinga) 1 mol of a diol (III) having an average molecular weight of from 400 to 4000,b) from 0.3 to 9 mol of an aliphatic or cycloaliphatic diol (IV) of 2 to 18 carbon atoms,c) from 0.3 to 9 mol of an aromatic diol (V) of 8 to 30 carbon atoms,d) from 0.01 to 1 mol of a trihydric alcohol (VI) of 3 to 18 carbon atoms,e) from 0.001 to 1 mol of a polyhydric alcohol (VII) of 3 to 14 carbon atoms which contains a tertiary amino group andf) an amount of a diisocyanate (VIII) of 6 to 30 carbon atoms such that the molar ratio of the isocyanate groups to the total number of hydroxyl groups in (III) to (VII) is from 1.05:1 to 1.4:1with2) a compound (IX) which contains one or more hydroxyl groups and one or more amino groups reactive toward isocyanate groups, the amount of (IX) being such that the number of reactive amino groups corresponds to the number of isocyanate groups in the polyurethane (II).The materials may be used as crosslinkable binder components for pigment-containing coatings, in particular for the production of magnetic recording materials.

    摘要翻译： 制备平均分子量为4000〜30,000的材料（I），其可通过使1）包含a）1摩尔平均分子量为400至4000的二醇（III）的聚氨酯（II）得到，b） 2〜18个碳原子的脂肪族或脂环族二醇（Ⅳ）为0.3〜9摩尔，c）0.3〜9摩尔碳原子数为8〜30的芳香族二醇（Ⅴ），d）0.01〜1摩尔 3〜18个碳原子的三元醇（Ⅵ），e）0.001〜1摩尔含有叔氨基的3〜14个碳原子的多元醇（Ⅶ），f）二异氰酸酯（Ⅷ） （III）至（VII）中的异氰酸酯基团与羟基的总摩尔比为1.05:1至1.4:1，其中2）含有一个或多个的化合物（IX） 或更多的羟基和一个或多个对异氰酸酯基反应的氨基，（IX）的量使得反应性氨基的数量对应于数目o 聚氨酯（II）中的异氰酸酯基团。 这些材料可以用作含颜料的涂料的可交联粘合剂组分，特别是用于生产磁记录材料。