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    Valve prosthesis and method for delivery
    11.
    发明授权
    Valve prosthesis and method for delivery 有权

    公开(公告)号：US10945841B2

    公开(公告)日：2021-03-16

    申请号：US16248564

    申请日：2019-01-15

    Applicant: MEDTRONIC, INC.

    Inventor： Igor Kovalsky ,  Ilia Hariton ,  Yossi Tuval ,  Nadav Yellin

    IPC: A61F2/24

    Abstract: Heart valve prostheses are provided for replacing a cardiac valve. The heart valve prosthesis includes a self-expanding frame including a first portion and a second portion. In the collapsed configuration, the first portion is positioned adjacent to the second portion. In the expanded configuration, the first portion moves to be positioned within an interior area of the second portion.

    Heart valve prostheses having multiple support arms and methods for percutaneous heart valve replacement
    12.
    发明授权
    Heart valve prostheses having multiple support arms and methods for percutaneous heart valve replacement 有权

    公开(公告)号：US10321992B2

    公开(公告)日：2019-06-18

    申请号：US15012533

    申请日：2016-02-01

    Applicant: Medtronic, Inc.

    Inventor： Jason Quill ,  Padraig Savage ,  Joshua Dwork ,  Kshitija Garde ,  Sarah Ahlberg ,  Igor Kovalsky

    IPC: A61F2/24

    Abstract: Prosthetic heart valve devices and associated methods for percutaneous or transcatheter heart valve replacement are disclosed herein. A heart valve prosthesis configured in accordance herewith includes a frame having a valve support and a plurality of support arms extending therefrom. The plurality of support arms may include a main support arm configured to extend from the valve support for capturing at least a portion of a valve leaflet of a native heart valve therebetween when the valve prosthesis is in an expanded configuration and deployed within the native heart valve. In addition, the plurality of support arms may include multiple supplemental support arms disposed about the circumference of the valve support that when deployed in the expanded configuration are configured to at least partially engage subannular tissue at the native heart valve.

    HEART VALVE PROSTHESIS
    13.
    发明申请
    HEART VALVE PROSTHESIS 审中-公开
    心脏瓣膜预防

    公开(公告)号：US20150119982A1

    公开(公告)日：2015-04-30

    申请号：US14519793

    申请日：2014-10-21

    Applicant: Medtronic, Inc

    Inventor： Jason Quill ,  Igor Kovalsky

    IPC: A61F2/24

    CPC classification number: A61F2/2409 ,  A61F2/2418 ,  A61F2230/005 ,  A61F2230/008

    Abstract: Mitral valve prosthesis are disclosed that include a frame or support structure having an inflow portion, a valve-retaining tubular portion and a pair of support arms. The inflow portion radially extends from a first end of the valve-retaining tubular portion and the pair of support arms are circumferentially spaced apart and radially extend from an opposing second end of the valve-retaining tubular portion. The inflow portion is formed from a plurality of struts that outwardly extend from the first end of the valve-retaining tubular portion with adjacent struts of the plurality of struts being joined, wherein each strut of the plurality of struts has a substantially s-shaped profile and at least one twisted area.

    Abstract translation: 公开了二尖瓣假体，其包括具有流入部分，阀保持管状部分和一对支撑臂的框架或支撑结构。 流入部分从阀保持管状部分的第一端径向延伸，并且一对支撑臂沿圆周间隔开并且从阀保持管状部分的相对的第二端径向延伸。 流入部分由多个支柱形成，多个支柱从阀保持管状部分的第一端向外延伸，多个支柱的相邻支柱被连接，其中多个支柱中的每个支柱具有基本上S形的轮廓 和至少一个扭曲区域。

    Anti-paravalvular leakage component for a transcatheter valve prosthesis
    14.
    发明授权
    Anti-paravalvular leakage component for a transcatheter valve prosthesis 有权
    用于经导管瓣膜假体的抗瓣膜泄漏组件

    公开(公告)号：US08986375B2

    公开(公告)日：2015-03-24

    申请号：US13795066

    申请日：2013-03-12

    Applicant: Medtronic, Inc.

    Inventor： Kshitija Garde ,  Philip Haarstad ,  Igor Kovalsky ,  Stephen Nash ,  Gianfranco Pellegrini ,  Finn Rinne ,  Matthew Rust ,  Jeffrey Sandstrom ,  Padraig Savage ,  William Steinberg

    IPC: A61F2/24

    CPC classification number: A61F2/2445 ,  A61F2/2403 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2250/0069

    Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the stent which includes a plurality of self-expanding struts and an annular sealing membrane. Each strut has a first end coupled to a distal end of the stent and a second end not coupled to the stent. Each anti-paravalvular leakage component is moveable between a compressed configuration and a deployed configuration. In the compressed configuration, each strut extends distally away from the distal end of the stent. In the deployed configuration, each strut extends proximally away from the distal end of the stent. In an embodiment hereof, the deployed strut has a C-shape and is twisted such that the C-shape lies in a plane substantially along or tangential with the outer surface of the stent. In another embodiment hereof, the deployed strut is rolled-up and extends radially away from the outer surface of the stent.

    Abstract translation: 经导管瓣膜假体包括可扩张的管状支架，支架内的假体瓣膜，以及耦合到环绕支架并包围多个自膨胀支柱和环形密封膜的抗瓣膜泄漏部件。 每个支柱具有联接到支架的远端的第一端和未联接到支架的第二端。 每个反paravalvular泄漏组件可在压缩配置和部署配置之间移动。 在压缩构型中，每个支柱远离支架远端延伸。 在展开的构造中，每个支柱向近端延伸远离支架的远端。 在本发明的一个实施例中，所展开的支柱具有C形并且被扭曲，使得C形位于与支架的外表面基本上沿或相切的平面中。 在本发明的另一个实施例中，部署的支柱被卷起并且从支架的外表面径向延伸。

    Valve Prosthesis and Method for Delivery
    16.
    发明申请
    Valve Prosthesis and Method for Delivery 有权
    瓣膜假体和交付方法

    公开(公告)号：US20140194983A1

    公开(公告)日：2014-07-10

    申请号：US13736494

    申请日：2013-01-08

    Applicant: MEDTRONIC, INC.

    Inventor： Igor Kovalsky ,  Ilia Hariton ,  Yossi Tuval ,  Nadav Yellin

    IPC: A61F2/24

    CPC classification number: A61F2/2445 ,  A61F2/2418 ,  A61F2210/0061 ,  A61F2230/0065 ,  A61F2250/0039 ,  A61F2250/006

    Abstract: Heart valve prostheses are provided for replacing a cardiac valve. The heart valve prosthesis includes a self-expanding frame including a first portion and a second portion. In the collapsed configuration, the first portion is positioned adjacent to the second portion. In the expanded configuration, the first portion moves to be positioned within an interior area of the second portion.

    Abstract translation: 提供心脏瓣膜假体以更换心脏瓣膜。 心脏瓣膜假体包括包括第一部分和第二部分的自扩张框架。 在折叠构造中，第一部分定位成与第二部分相邻。 在扩展配置中，第一部分移动以定位在第二部分的内部区域内。

    Valve Prosthesis and Method for Delivery
    17.
    发明申请
    Valve Prosthesis and Method for Delivery 有权
    瓣膜假体和交付方法

    公开(公告)号：US20140194982A1

    公开(公告)日：2014-07-10

    申请号：US13736460

    申请日：2013-01-08

    Applicant: MEDTRONIC, INC.

    Inventor： Igor Kovalsky ,  Jason Quill ,  Daniel Glozman ,  Ilia Hariton ,  Yossi Tuval ,  Nadav Yellin

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2/2412 ,  A61F2230/001 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0078 ,  A61F2230/008

    Abstract: In some embodiments, a valve prosthesis includes an inlet portion that is substantially s-shaped and configured to engage the floor of the outflow tract of the native heart atrium. In some embodiments, a valve prosthesis includes a chordae guiding element configured to reduce bending of the chordae to reduce stress on the chordae during the cardiac cycle. In some embodiments, a valve prosthesis includes a central portion having an hourglass shape configured to pinch a native annulus in order to provide axial fixation of the valve prosthesis within a valve site. In some embodiments, a valve prosthesis includes a frame having an outflow end that is flared to provide a gap between an outflow end of the frame and an outflow end of prosthetic leaflets when the prosthetic leaflets are fully opened.

    Abstract translation: 在一些实施例中，瓣膜假体包括入口部分，其基本上为S形并且构造成接合天然心脏心房的流出道的底部。 在一些实施例中，瓣膜假体包括腱索引导元件，其被配置为减少腱索的弯曲以减少在心脏周期期间腱索上的应力。 在一些实施例中，瓣膜假体包括具有沙漏形状的中心部分，其构造成夹住天然环带，以便在瓣膜部位内提供瓣膜假体的轴向固定。 在一些实施例中，瓣膜假体包括具有流出端的框架，所述流出端在所述假体叶片完全打开时，所述流出端被展开以在所述框架的流出端和假体叶片的流出端之间提供间隙。

    Heart valve prostheses having multiple support arms and methods for percutaneous heart valve replacement
    19.
    发明授权
    Heart valve prostheses having multiple support arms and methods for percutaneous heart valve replacement 有权

    公开(公告)号：US11278397B2

    公开(公告)日：2022-03-22

    申请号：US16403769

    申请日：2019-05-06

    Applicant: Medtronic, Inc.

    Inventor： Jason Quill ,  Padraig Savage ,  Joshua Dwork ,  Kshitija Garde ,  Sarah Ahlberg ,  Igor Kovalsky

    IPC: A61F2/24

    Abstract: Prosthetic heart valve devices and associated methods for percutaneous or transcatheter heart valve replacement are disclosed herein. A heart valve prosthesis configured in accordance herewith includes a frame having a valve support and a plurality of support arms extending therefrom. The plurality of support arms may include a main support arm configured to extend from the valve support for capturing at least a portion of a valve leaflet of a native heart valve therebetween when the valve prosthesis is in an expanded configuration and deployed within the native heart valve. In addition, the plurality of support arms may include multiple supplemental support arms disposed about the circumference of the valve support that when deployed in the expanded configuration are configured to at least partially engage subannular tissue at the native heart valve.

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