公开(公告)号：US20050046944A1

公开(公告)日：2005-03-03

申请号：US10911926

申请日：2004-08-05

申请人： Olga Shenderova ,  Gary McGuire ,  Alexander Shenderov

发明人： Olga Shenderova ,  Gary McGuire ,  Alexander Shenderov

IPC分类号： G02B27/44 ,  G06K9/40

CPC分类号： G02B5/1842 ,  G02B5/188 ,  G02B27/4205

摘要： An imaging device consistent with one of numerous embodiments has an opaque planar sheet with a plurality of pinholes defining a photon sieve in the sheet, wherein, the photon sieve comprises at least first and second regions. The first region exhibits a first focal length, a first field of view, a first transmissivity, a first resolution and a first wavelength, and the second region exhibiting a second focal length, a second field of view, a second transmissivity, a second resolution and a second wavelength. At least one of the first focal length, the first wavelength, the first transmissivity, the first resolution and the first field of view is different from the second focal length, the second wavelength, the second transmissivity, the second resolution and the second field of view. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.

摘要翻译： 与许多实施例之一相一致的成像装置具有不透明平板，其具有在片材中限定光子筛的多个针孔，其中，光子筛包括至少第一和第二区域。 第一区域呈现第一焦距，第一视场，第一透射率，第一分辨率和第一波长，第二区域呈现第二焦距，第二视场，第二透射率，第二分辨率 和第二波长。 第一焦距，第一波长，第一透射率，第一分辨率和第一视场中的至少一个不同于第二焦距，第二波长，第二透射率，第二分辨率和第二场 视图。 该摘要不被认为是限制性的，因为其他实施例可能偏离本摘要中描述的特征。

公开(公告)号：US20100130369A1

公开(公告)日：2010-05-27

申请号：US12596897

申请日：2008-03-24

申请人： Alexander Shenderov ,  Richard Kouri ,  Varvara Grichko

发明人： Alexander Shenderov ,  Richard Kouri ,  Varvara Grichko

IPC分类号： C40B30/00 ,  C40B50/08

CPC分类号： C12Q1/6837 ,  C12Q2563/179 ,  C12Q2563/155 ,  C12Q2531/125

摘要： Various methods, such as a method of detecting SNPs, involving (a) introducing onto a droplet actuator a solution comprising genomic DNA, extension oligos and suspension array beads; (b) dispensing on the droplet actuator one bead per droplet; (c) cleaving DNA from the bead in each droplet; (d) amplifying the cleaved DNA; (e) detecting SNP signals and barcode signals from the amplified DNA.

摘要翻译： 各种方法，例如检测SNP的方法，涉及（a）向液滴致动器引入包含基因组DNA，延伸寡核苷酸和悬浮阵列珠的溶液; （b）在液滴致动器上分配每个液滴一个珠; （c）在每个液滴中从珠中切割DNA; （d）扩增切割的DNA; （e）从扩增的DNA检测SNP信号和条形码信号。

公开(公告)号：US06773566B2

公开(公告)日：2004-08-10

申请号：US09943675

申请日：2001-08-30

申请人： Alexander Shenderov

发明人： Alexander Shenderov

IPC分类号： G01N2726

CPC分类号： B01L3/502784 ,  B01L2200/0673 ,  B01L2300/0829 ,  B01L2300/0874 ,  B01L2300/089 ,  B01L2400/0415 ,  B01L2400/0427 ,  F04B19/006

摘要： An apparatus for inducing movement of an electrolytic droplet includes: a housing having an internal volume filled with a liquid immiscible with an electrolytic droplet; a distribution plate positioned within the chamber having an aperture and dividing the housing into upper and lower chambers; a lower electrode positioned below the lower chamber and the aperture in the distribution plate and being separated from the lower chamber by an overlying hydrophobic insulative layer; an upper electrode located above the upper chamber and the aperture of the distribution plate and being separated from the upper chamber by an underlying hydrophobic insulative layer; and first, second and third voltage generators that are electrically connected to, respectively, the lower and upper electrodes and the distribution plate. The voltage generators are configured to apply electrical potentials to the lower and upper electrodes and the distribution plate, thereby inducing movement of the electrolytic droplet between the hydrophobic layers.

摘要翻译： 用于引起电解液滴运动的装置包括：壳体，其具有填充有与电解液滴不混溶的液体的内部体积; 位于所述腔室内的分配板具有孔，并将所述壳体分成上腔室和下腔室; 位于下腔室下方的下电极和分配板中的孔，并通过上覆的疏水绝缘层与下室隔开; 位于上室上方的上电极和分配板的孔，并通过下面的疏水绝缘层与上室隔离; 以及分别电连接到下电极和上电极以及分配板的第一，第二和第三电压发生器。 电压发生器被配置为向下电极和上电极和分配板施加电势，从而引起电解液滴在疏水层之间的移动。

公开(公告)号：US20100206094A1

公开(公告)日：2010-08-19

申请号：US12596898

申请日：2008-04-23

申请人： Alexander Shenderov

发明人： Alexander Shenderov

IPC分类号： G01N1/22

CPC分类号： G01N1/4005 ,  G01N2001/4016

摘要： An apparatus and a method for concentrating a target substance in a liquid has been invented. The apparatus comprises a first reservoir with inlet openings for introducing a fluid comprising a target substance into the first reservoir and a second reservoir separated from the first reservoir by a partition permeable to permit the fluid to traverse the partition while retaining the target substance in the first reservoir.

摘要翻译： 已经发明了用于将目标物质浓缩在液体中的装置和方法。 该装置包括具有入口开口的第一储存器，用于将包含目标物质的流体引入到第一储存器中;以及第二储存器，其与第一储存器分隔开，所述第二储存器具有可渗透的隔板，以允许流体横过隔板，同时将目标物质保持在第一储存器中 水库

公开(公告)号：US20070267294A1

公开(公告)日：2007-11-22

申请号：US11833576

申请日：2007-08-03

申请人： Alexander Shenderov

发明人： Alexander Shenderov

IPC分类号： G01N27/00

CPC分类号： B01L3/502792 ,  B01F13/0071 ,  B01F13/0076 ,  B01F2005/0017 ,  B01L3/502738 ,  B01L3/502746 ,  B01L3/502784 ,  B01L2200/0673 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2300/0819 ,  B01L2300/0867 ,  B01L2300/089 ,  B01L2400/0415 ,  B01L2400/0427 ,  F04B17/00 ,  F04B19/006 ,  F16K99/0001 ,  F16K99/0017 ,  G02B26/005

摘要： A series of microactuators for manipulating small quantities of liquids, and methods of using these for manipulating liquids, are disclosed. The microactuators are based on the phenomenon of electrowetting and contain no moving parts. The force acting on the liquid is a potential-dependent gradient of adhesion energy between the liquid and a solid insulating surface.

摘要翻译： 公开了一系列用于操作少量液体的微致动器以及使用它们来操纵液体的方法。 微致动器基于电润湿现象，不含运动部件。 作用在液体上的力是液体和固体绝缘表面之间的粘附能的电势梯度。